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Preparation and evaluation of 186/188Re-labeled antibody (A7) for radioimmunotherapy with rhenium(I) tricarbonyl core as a chelate siteEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion 186/188Re-labeled A7 showed high uptakes in the tumor. However, further modification of the labeling method would be necessary to improve radiochemical yields and their biodistribution. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s12149-009-0319-4Authors Kazuma Ogawa, Kanazawa University Graduate School of Natural Science and Technology Kakuma-machi Kanazawa 920-1192 JapanHidekazu Kawashima, Kyoto University Hospital Kyoto JapanSeigo Kinuya, Kanazawa University Graduate School of Medical Sciences Kanazawa JapanKazuhiro Shiba, Kanazawa University Advanced Science Resear...
Source: Annals of Nuclear Medicine - November 17, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

The relationship between reverse redistribution of 99mTc-tetrofosmin in sub-acute phase and left ventricular functional recovery in chronic phase in patients with acute myocardial infarctionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion These findings suggested that quantitative evaluation of RRD by gated 99mTc-tetrofosmin SPECT in the sub-acute phase can predict recovery of left ventricular function in the chronic phase with higher accuracy in patients with AMI who underwent direct PCI. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s12149-009-0318-5Authors Sei Fujiwara, Kobe University Graduate School of Medicine Division of Cardiovascular Medicine, Department of Internal Medicine 7-5-1 Kusunoki-cho, Chuo-ku Kobe Hyogo 650-0017 JapanHideyuki Shiotani, Kobe University Graduate School of Health Sciences Ko...
Source: Annals of Nuclear Medicine - November 17, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Prognostic value of myocardial perfusion SPECT images in combination with the maximal heart rate at exercise testing in Japanese patients with suspected ischemic heart disease: a sub-analysis of J-ACCESSEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion The combination of SSS using Ex-SPECT and the maximal heart rate is a useful predictor of cardiac events in patients with suspected coronary artery disease. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s12149-009-0315-8Authors Kenji Ueshima, Kyoto University Graduate School of Medicine EBM Research Center Yoshida-Konoecho, Sakyo-ku Kyoto 606-8501 JapanAkira Yamashina, Tokyo Medical University Second Department of Internal Medicine Tokyo JapanSatoru Usami, Kyoto University Graduate School of Medicine Department of Medicine and Clinical Science Kyoto JapanShinji Yasuno, Kyo...
Source: Annals of Nuclear Medicine - November 6, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Diagnostic performance of fluorodeoxyglucose-positron emission tomography/computed tomography of breast cancer in detecting axillary lymph node metastasis: comparison with ultrasonography and contrast-enhanced CTEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions PET/CT showed poor sensitivity and high specificity in the detection of axillary lymph node metastasis of breast cancer. Diagnostic performance of PET/CT was not superior to that of ultrasonography and contrast-enhanced CT. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s12149-009-0314-9Authors Shuichi Monzawa, Hyogo Cancer Center Department of Radiology Kitaohji 13-70 Akashi Hyogo 673-8558 JapanShuji Adachi, Hyogo Cancer Center Department of Radiology Kitaohji 13-70 Akashi Hyogo 673-8558 JapanKayo Suzuki, Hyogo Cancer Center Department of Radiology Kitaohji 13-70 Akashi H...
Source: Annals of Nuclear Medicine - October 29, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

FDG PET findings in a case with acute pulmonary silicosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract A 21-year-old male having a history of 4 years of working at a denim factory as a sandblaster was diagnosed with pulmonary silicosis and he was also an active smoker. Productive cough, dyspnea on effort, night sweats, and weight loss in a short period of time were his complaints. Chronic occupational exposure to tiny particles of silicon dioxide can stimulate parenchymal inflammation, collagen synthesis and, ultimately pulmonary fibrosis called silicosis. A typical history of exposure and chest X-ray is usually enough for diagnosis. No effective treatment exists except supportive care. Although...
Source: Annals of Nuclear Medicine - October 29, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Intense accumulation of 18F-FDG, not enhancement on MRI, helps to guide the surgical biopsy accurately in soft tissue tumorsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Soft tissue sarcomas are a highly heterogeneous group of malignancies that arise from mesenchymal tissues. Grading of soft tissue sarcomas is an important prerequisite for the choice of therapy and estimation of prognosis. However, incisional biopsy of huge soft tissue sarcoma lesions frequently fails to provide an accurate diagnosis when there is a benign component, cystic changes and/or necrosis. MRI is helpful in evaluating the extent of the sarcoma lesion, vascularization, invasiveness and integrity of surrounding tissue, but definitive differentiation of benignity and malignancy is not possible...
Source: Annals of Nuclear Medicine - October 27, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Bibliometric study of radiation application on microdose useful for new drug developmentEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract In spite of the sharp increase in both private and government R&D fund, the number of newly approved medicines for market had decreased since the 1990s. This is attributed to a large extent to the bottleneck in the critical path arising from the great disparity between animal model in pre-clinical trial and human model in clinical trial. This bottleneck may be expected to be gotten rid of by change in paradigm of drug development based on microdosing, which is enabled by radiation-related imaging technology. However, this is impossible without being accompanied by interdisciplinary joint researches,...
Source: Annals of Nuclear Medicine - October 27, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Gamma scintigraphy of111In-labelled branched chain polypeptides (BCP) with a poly(L-lysine) backbone in mice with mammary carcinoma: Effect of charge on biodistribution and tumour imaging potentialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Radiolabelled synthetic branched chain polypeptides (BCP) represent a new and novel range of materials with potential as radiopharmaceuticals. Preliminary imaging studies have been under-taken with111In-labelled BCP in mice with subcutaneously transplanted mammary carcinoma. Four polypeptides each with a poly(L-lysine) backbone and side chains of DL-alanine residues were studied. These were AK, which is polycationic, EAK which is amphoteric, having additional glutamic acid residues at the end of the side chains, and AcEAK (anionic) and SucEAK (highly polyanionic) where the terminal glutamic acid ami...
Source: Annals of Nuclear Medicine - October 26, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Award of the best A.N.M. paperEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Content Type Journal ArticleCategory AnnouncementDOI 10.1007/BF03168410Authors Junji Konishi, The Japanese Society of Nuclear Medicine Japan Journal Annals of Nuclear MedicineOnline ISSN 1864-6433Print ISSN 0914-7187 Journal Volume Volume 9 Journal Issue Volume 9, Number 4 / December, 1995 (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - October 26, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

The “Fisherman’s Waders” sign in a bone scan of inferior vena cava thrombosis associated with nephrotic syndromeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract This paper presents a 61-year-old male patient with nephrotic syndrome, hypercoagulability and IVC thrombosis. Increased soft tissue uptake below the level of the mid chest was seen in his bone scan. The term “Fisherman’s Waders” sign is suggested for this finding, whose recognition may permit the identification of inferior vena cava obstruction in bone scans. The existence of a cavoportal shunt was also confirmed by dynamic scintigraphy. Content Type Journal ArticleCategory Case ReportDOI 10.1007/BF03168407Authors Lee-shing Chu, Taipei Veterans General Hospital, National Defence Medical C...
Source: Annals of Nuclear Medicine - October 26, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Morphine-augmented cholescintigraphy enhances duodenogastric refluxEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Morphine intervention in cholescintigraphy decreases imaging time to diagnose acute cholecystitis. Not infrequently we observe duodenogastric reflux during scintigraphy with and without morphine intervention. To evaluate occurrence of duodenogastric reflux related to morphine, we reviewed 55 patients who underwent cholescintigraphy with (32) and without (23) morphine intervention. Morphine was injected when there was bowel activity with non-visualization of the gallbladder at 60 min. Duodenogastric reflux was identified by the appearance of activity in the area just below or immediately adjacent to ...
Source: Annals of Nuclear Medicine - October 26, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

New design of N-isopropyl-p-[123I]iodoamphetamphetamine (123I-IMP) lung imaging in the patient with lung cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Content Type Journal ArticleCategory Original ArticlesDOI 10.1007/BF03168403Authors Eiko Tanaka Journal Annals of Nuclear MedicineOnline ISSN 1864-6433Print ISSN 0914-7187 Journal Volume Volume 9 Journal Issue Volume 9, Number 4 / December, 1995 (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - October 26, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Transit through the distal quarter of the oesophagus in young childrenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract The transit time of 800 individual boluses through the distal quarter of the oesophagus was measured in 33 scintigraphic oesophageal studies which had been selected as typifying normal swallows in children. The results show that, in children, transit time through the distal quarter including the lower oesophageal sphincter is normally less than 2 seconds and that transit tends to be slower during the first 4 seconds after onset of swallowing. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/BF03168401Authors Michael Cronin, University of Cape Town and Red Cross War Memorial Child...
Source: Annals of Nuclear Medicine - October 26, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Error analysis of autoradiography method for measurement of cerebral blood flow by123I-IMP brain SPECT: A comparison study with table look-up method and microsphere model methodEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract N-isopropyl-p-[123I]iodoamphetamine (IMP) has been commonly used as a cerebral blood flow tracer, but, significant clearance of IMP from the brain to the blood causes underestimation of cerebral blood flow (CBF) as compared with true CBF when the conventional microsphere model method is applied. Previously, we reported an “Autoradiography method” (ARG method) for measuring CBF by using IMP in which this clearance effect was corrected. This method was based on a two-compartment model (influx: K1 efflux: k2, K1/k2 = distribution volume of IMP (Vd)), the K1 (corresponding to CBF) being obtained from...
Source: Annals of Nuclear Medicine - October 26, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Clinical studies of alveolar-capillary permeability using technetium-99m DTPA aerosolEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Soluble radioaerosols such as technetium-99m diethylene triamine pentacetate (DTPA) permit simple quantitative studies of alveolar-capillary permeability to be performed, since the submicronic aerosols are deposited mainly at the lung periphery and are cleared across the alveolar-capillary membrane. Regional alterations in permeability can also be noted using this radionuclide technique. We have measured the pulmonary epithelial permeability in normal subjects and the alteration in smokers, in glue-sniffers, in patients with inhalation burns, in chronic obstructive pulmonary disease (COPD) and in pa...
Source: Annals of Nuclear Medicine - October 26, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Abnormal extrapulmonary accumulation of99mTc-MAA during lung perfusion scanningEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present fourteen patients with an abnormal extrapulmonary accumulation on lung perfusion scintigraphy with99mTc-macroaggregated albumin (MAA), who were examined during the last decade. These included six patients with lung cancer, four with pulmonary arterio-venous fistula, two with congenital heart disease, one with inferior vena cava (IVC) syndrome and one with congenital bronchogenic cyst. All six patients with lung cancer had superior vena cava (SVC) syndrome, and the tumor invaded the thoracic wall. As causes of abnormal accumulation, fourteen patients had a right-to-left shunt, and one patient with IVC syndr...
Source: Annals of Nuclear Medicine - October 26, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Parametric imaging in nuclear medicineEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Content Type Journal ArticleCategory ReviewDOI 10.1007/BF03168396Authors Niels A. Lassen, Bispebjerg Hospital Department of Clinical Physiology and Nuclear Medicine DK-2400 Copenhagen, NV DenmarkHidehiro Iida, Akita Research Institute of Brain and Blood Vessels Department of Radiology and Nuclear Medicine 6-10, Senshu-kubota-machi 010 Akita JapanIwao Kanno, Akita Research Institute of Brain and Blood Vessels Department of Radiology and Nuclear Medicine 6-10, Senshu-kubota-machi 010 Akita Japan Journal Annals of Nuclear MedicineOnline ISSN 1864-6433Print ISSN 0914-7187 Journal Volume Volume 9 Journal Issu...
Source: Annals of Nuclear Medicine - October 26, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Validation of noninvasive quantification of rCBF compared with dynamic/integral method by using positron emission tomography and oxygen-15 labeled waterEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study proposes a new solution for the quantification of rCBF pixel-by-pixel using PET and15O-H2O. The method represents an application of weighted integration that uses PET image only, requiring no input function of arterial blood. It generates the rCBF image quickly and automatically. Simulation studies revealed that the calculation of rCBF was fairly stable as long as a relatively shorter scan frame time and longer scan time were selected. Calculated images of actual PET study by this method correlated significantly with those identified by the dynamic/integral method. Because this procedure could detect whole b...
Source: Annals of Nuclear Medicine - October 26, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

The functional hepatic volume assessed by99mTc-GSA hepatic scintigraphyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract The accuracy of measurement of the functional hepatic volume by single photon emission computed tomography (SPECT) with99mTc-galactosyl serum albumin (99mTc-GSA) was evaluated.99mTc-GSA planar scintigraphic images were obtained dynamically and the hepatic SPECT imaging was then performed in 25 patients with hepatobiliary tumors. The patients were divided into 4 groups with normal hepatic function, and mild, moderate and severe hepatic dysfunction. The functional hepatic volume determined by SPECT was compared with the morphological hepatic volume determined by computed tomography. The ratio of the he...
Source: Annals of Nuclear Medicine - October 26, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Sequential subtraction scintigraphy with99mTc-RBC for the early detection of gastrointestinal bleedingEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract To improve the early detectability of gastrointestinal (GI) bleeding, we have developed a new subtraction scintigraphic technique usingin vivo labeled99mTc red blood cells (RBC). Use of this new sequential subtraction method every 5 min makes it possible to detect early the bleeding site and calculate the bleeding rate. In phantom experiments, focal activity was detected on subtraction images at pump rates of more than 0.20 ml/min at any urethane thickness, but was negative on conventional scintigrams. The calculated pump rate by the subtraction method correlated well with the actual syringe pump ra...
Source: Annals of Nuclear Medicine - October 26, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

The relevance of interictal rCBF brain SPECT in temporal lobe epilepsy: Diagnostical value and effects of spatial resolutionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, the interictal rCBF-SPECT revealed reasonable sensitivity and PPV in pt. suffering from focal temporal lobe epilepsy and modern SPECT systems showed significantly improved results. Since there is a variety of possible reasons for regional cortical hypoperfusion, the interictal SPECT could add significant information prior to the application of ECoG. This specially appeared to be useful in patients with a normal MRI scan. Furthermore, in patients presenting with a clear pathology on MRI and a corresponding EEG focus, ECoG could be avoided if the interictal rCBF-SPECT additionally showed localized and sin...
Source: Annals of Nuclear Medicine - October 26, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

The 6th Asia and Oceania Congress of Nuclear Medicine and Biology A conjoint meeting with the 36th Annual Meeting of the Japanese Society of Nuclear MedicineEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Content Type Journal ArticleDOI 10.1007/BF03168411 Journal Annals of Nuclear MedicineOnline ISSN 1864-6433Print ISSN 0914-7187 Journal Volume Volume 9 Journal Issue Volume 9, Number 4 / December, 1995 (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - October 26, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Intense accumulation of Tc-99m MDP and Ga-67 in multiple periapical cemental dysplasiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract A case of multiple periapical cementai dysplasia is presented and intensive accumulation of Tc-99m MDP and Ga-67 is described. A 53-year-old woman was admitted with an intermittent pain and swelling of the left buccal region. The radiograph showed multiple sclerotic masses covering entire periapical regions of the teeth, in both the maxilla and mandibula. Biopsy of the maxilla facilitated a definitive diagnosis of multiple periapical cementai dysplasia. Content Type Journal ArticleCategory Case ReportDOI 10.1007/BF03168408Authors Suzuka Taki, Tonami General Hospital Department of Radiology 1-61 ...
Source: Annals of Nuclear Medicine - October 26, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Correlation of left ventricular dyssynchrony with myocardial stunning using dual single photon emission computed tomography of 123iodine-β-methyl iodophenyl pentadecanoic acid and 201thallium scintigraphy after reperfusion therapyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion LV dyssynchrony after reperfusion therapy correlates positively with Tl–BMIPP discrepancy, reflecting acute myocardial stunning, in which ventricular contraction improves during the chronic phase. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s12149-009-0312-yAuthors Yoshiaki Maruyama, Saitama Medical University Department of Health Promotion, Saitama Medical Center 1981 Kamoda Kawagoe Saitama 350-8550 JapanNobuyuki Masaki, Saitama Medical University Department of Cardiology, Saitama Medical Center Kawagoe Saitama 350-8550 JapanYuji Shimizu, Saitama Medical University De...
Source: Annals of Nuclear Medicine - October 23, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Esophageal transit scintigraphy and structured questionnaire in patients with systemic sclerosis with endoscopically proven reflux esophagitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion A combination of esophageal scintigraphy and structured questionnaire demonstrated different aspects of esophageal dysfunction, namely dysmotility and GER. Patients with high QS and dysmotility may be indicated for further evaluation including endoscopic examination and medical treatment. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s12149-009-0310-0Authors Kenichi Nakajima, Kanazawa University Hospital Department of Nuclear Medicine 13-1 Takara-machi Kanazawa 920-8641 JapanAnri Inaki, Kanazawa University Hospital Department of Nuclear Medicine 13-1 Takara-machi Kanazawa...
Source: Annals of Nuclear Medicine - October 23, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Radioimmunodetection of cancer of gastrointestinal tract and liver metastasis with I-131 anti-CEA and I-131 anti-CA19-9 monoclonal antibody cocktail (IMACIS-1)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract We evaluated the intravenous infusion of a cocktail of I-131 anti-CEA and anti-C A19-9 monoclonal antibody F(ab’)2 (IMACIS-1) in patients with gastrointestinal neoplasm and liver metastases in order to assess its efficacy in detecting the presence of cancer. Seven patients with primary or recurrent gastrointestinal cancer in whom liver metastases were also detected were studied. Accumulation of radioactivity in the primary tumor was seen in only one patient. Visualization of the liver metastases was achieved in all patients. Thus detection of liver metastasis was better than in primary or recurren...
Source: Annals of Nuclear Medicine - October 17, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Potential for qualitative diagnosis of tumors and tumorous lesions in the liver with Tc-99m-GSA SPECT —Correlation with pathological evaluation and MRI findings—Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract To evaluate the effect of technetium-99m-labeled DTPA-galactosyl human serum albumin (Tc-99m-GSA) SPECT imaging for qualitative diagnosis of hepatic lesions. The subjects were 29 patients with pathologically confirmed hepatic lesions (21 malignant and 8 benign lesions). SPECT data were obtained at about 30 minutes after injecting 185 MBq (5 mCi) of Tc-99m-GSA. The GSA SPECT findings were compared with those of pathological evaluation and T2-weighted MR images (T2WI). Of 29 lesions, 17 showed decreased accumulation, and three exhibited increased accumulation. The other nine lesions were unde...
Source: Annals of Nuclear Medicine - October 17, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Comparison between rebinning methods and geometric re-projection for the estimation of missing oblique data in 3D-PETEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions We show that iterative FOREPROJ provides projection data with high accuracy 60% less time than geometric re-projection. Content Type Journal ArticleCategory Technical NoteDOI 10.1007/s12149-009-0306-9Authors Fayçal Ben Bouallègue, Montpellier Science University Department of Mathematics 34095 Montpellier FranceJean-François Crouzet, Montpellier Science University Department of Mathematics 34095 Montpellier FranceDenis Mariano-Goulart, Montpellier Medical University Biophysics and Nuclear Medicine Department 34295 Montpellier France Journal Annals of Nuclear MedicineOnline ISSN 1864...
Source: Annals of Nuclear Medicine - October 16, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Whole-body FDG-PET/CT on rheumatoid arthritis of large jointsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion FDG-PET/CT represents the inflammatory activity in large joints in patients with RA accurately and sensitively and may be helpful for early evaluations of the extent of RA throughout the whole body including high risk lesion of atlanto-axial joint. Furthermore, the visual FDG uptake score may be useful for evaluating arthritis in large joints. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s12149-009-0305-xAuthors Kazuo Kubota, International Medical Center of Japan Toyama Hospital Department of Radiology, Division of Nuclear Medicine 1-21-1 Toyama, Shinjuku-ku Tokyo 162-86...
Source: Annals of Nuclear Medicine - October 15, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

18F-FDG-PET findings of rare case of nonsecretory plasmablastic myelomaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present a rare case of nonsecretory plasmablastic myeloma detected by 18F-FDG-PET. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s12149-009-0300-2Authors Hiroko Kaibara, Kurume University School of Medicine Division of Nuclear Medicine, PET Center and Department of Radiology 67 Asahi-machi Kurume Fukuoka 830-0011 JapanHayato Kaida, Kurume University School of Medicine Division of Nuclear Medicine, PET Center and Department of Radiology 67 Asahi-machi Kurume Fukuoka 830-0011 JapanMasatoshi Ishibashi, Kurume University School of Medicine Division of Nuclear Medicine, PET Center and Department of Radiol...
Source: Annals of Nuclear Medicine - October 8, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Problems of [S-methyl-11C]-L-methionine as a protein synthesis marker in the pancreasEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract To evaluate the possibility of [S-methyl-11C]-L-methionine as a protein synthesis marker in the pancreas, the effect of various labeling positions in the accumulation and metabolism of14C-labeled L-methionines (S-methyl-14C, 1-14C and 3, 4-14C) was studied. In mouse biodistribution studies, the methionines showed differing patterns of labeling position-dependent pancreatic accumulation. In the case of [S-methyl-14C]-L-methionine, protein-incorporation and methyl-transformation equally served as retention mechanisms in the pancreas, indicating [S-methyl-11C]-L-methionme’s unsuitability as a pancreat...
Source: Annals of Nuclear Medicine - October 4, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Gallium-67 uptake in fibrous dysplasia of the boneEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract In a 43-year-old woman with fibrous dysplasia of the ribs and facial bone and in a 40-year-old man with fibrous dysplasia of the facial bone, there were considerable increases in the uptake of Tc-99m methylenediphosphonate (Tc-99m MDP) and Gallium-67 citrate. Fibrous dysplasia should be added to differential diagnosis of high Gallium-67 citrate uptake in the bone lesions. Content Type Journal ArticleCategory Case ReportDOI 10.1007/BF03165658Authors Hiroaki Hoshi, Miyazaki Medical College Department of Radiology 5200, Kihara, Kiyotake-cho, Miyazaki-gun 88916 Miyazaki-ken JapanShigemi Futami, Miyaz...
Source: Annals of Nuclear Medicine - October 4, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

The japanese society of nuclear medicineEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Content Type Journal ArticleDOI 10.1007/BF03165657 Journal Annals of Nuclear MedicineOnline ISSN 1864-6433Print ISSN 0914-7187 Journal Volume Volume 4 Journal Issue Volume 4, Number 1 / April, 1990 (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - October 4, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Influence of age on left ventricular performance during exercise in normal Japanese subject: Assessment by radionuclide ventriculographyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract To assess the effects of age on left ventricular performance, multistage supine ergometer exercise radionuclide ventriculography (RNV) was performed in 92 normal subjects. The subjects ranged in age from 24 to 86 years and were free of cardiopulmonary disease and diabetes. Age-related changes in exercise duration, left ventricular end-diastolic volume (LVEDV), left ventricular end-systolic volume (LVESV), cardiac output (CO) left ventricular ejection fraction (LVEF), left ventricular dv/dt, systolic and diastolic time indexes of dv/dt, and peak systolic pressure/left ventricular end-systolic volume ...
Source: Annals of Nuclear Medicine - October 4, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Differentiation of bronchogenic carcinoma from secondary changes, obstructive pneumonitis and/or collapse by I-123 IMP lung imagingEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Serial lung images with N-isopropyl-p-[I-123]-iodoamphetamine (I-123 IMP) were obtained to assess the imaging findings and to clarify the lesion to uptake relationships in 74 lesions in 73 patients with various histological types of bronchogenic carcinoma. A decreased uptake area was observed in all 74 lesions in the initial one or two-min I-123 IMP image. The initial image was analogous to a Tc-99m MAA lung perfusion image in 70 patients in whom both lung imaging procedures were performed. The imaging findings changed following this initial phase. At 4 hr, the lesion was depicted as either areas of...
Source: Annals of Nuclear Medicine - October 4, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Visualization of the bone/bone marrow of lower extremities in Ga-67 whole-body imagesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, the pattern of Ga-67 uptake by the bone/bone marrow of the lower extremities fairly closely reflects the status of iron metabolism. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/BF03165654Authors Kiyoshi Koizumi, Yamanashi Medical College Department of Radiology Tamaho-cho, Nakakoma-gun 409-38 Yamanashi-ken JapanGuio Uchiyama, Yamanashi Medical College Department of Radiology Tamaho-cho, Nakakoma-gun 409-38 Yamanashi-ken JapanTsutomu Araki, Yamanashi Medical College Department of Radiology Tamaho-cho, Nakakoma-gun 409-38 Yamanashi-ken JapanToshihiko Hihara, Yamanashi Medical College ...
Source: Annals of Nuclear Medicine - October 4, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Methodological aspects for free hormone estimation using microencapsulated antibody method—The effects of hormone binding protein on permeability of microcapsule membraneEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract The effect of T4 non-carrying thyroxine binding globulin (TBG) on free thyroxine determination using the microencapsulated antibody method was studied, to investigate the precise reliability of the membrane and to find possible applications for estimating other free steroid hormones. When increased amounts of purified TBG were added to a test tube containing microcapsule suspension, it affected the accuracy of the results. We found that with higher amounts,125I-T4 leaked through the membrane into the medium, thereby giving a falsely increased free T4 result. Our finding indicates that further improve...
Source: Annals of Nuclear Medicine - October 4, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

The 6th Asia and Oceania Congress of Nuclear Medicine and Biology a conjoint with the 36th Annual Meeting of the Japanese Society of Nuclear MedicineEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Content Type Journal ArticleDOI 10.1007/BF03165408 Journal Annals of Nuclear MedicineOnline ISSN 1864-6433Print ISSN 0914-7187 Journal Volume Volume 10 Journal Issue Volume 10, Number 2 / June, 1996 (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - September 30, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Award of the best A.N.M. paperEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Content Type Journal ArticleCategory AnnouncementDOI 10.1007/BF03165407Authors Junji Konishi, The Japanese Society of Nuclear Medicine Japan Journal Annals of Nuclear MedicineOnline ISSN 1864-6433Print ISSN 0914-7187 Journal Volume Volume 10 Journal Issue Volume 10, Number 2 / June, 1996 (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - September 30, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Application of Tc-99m-tetrofosmin as a tumor imaging agent: Comparison with Tl-201Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, early uptakes of both the agents were similar but their retention patterns were different. Tc-99m-tetrofosmin may be used for tumor imaging though more studies are required to evaluate diagnostic accuracy and the significance of delayed images. Content Type Journal ArticleCategory Short CommunicationDOI 10.1007/BF03165405Authors Ali S. Arbab, Yamanashi Medical University Department of Radiology Tamaho-cho, Nakakoma-gun 409-38 Yamanashi JapanKiyoshi Koizumi, Yamanashi Medical University Department of Radiology Tamaho-cho, Nakakoma-gun 409-38 Yamanashi JapanTakao Arai, Yamanashi Medical University Depar...
Source: Annals of Nuclear Medicine - September 30, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

A brain uptake study of [1-11C]hexanoate in the mouse: The effect of hypoxia, starvation and substrate competitionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract We evaluated the potential of sodium [1-11C]hexanoate (11C-HA) as a radiopharmaceutical with which to assess oxidative metabolism of the brain by PET.11C-HA, sodium [1-14C]acetate and [3H]deoxyglucose were simultaneously injected into mice under control, hypoxic and starving conditions. In the control, the brain uptake of11C was maximal at 3 min (% ID/g = 2.2–2.5), being twice as high as that of14C, followed by a gradual clearance. The time-radioactivity curve of11C was similar to that of14C. Hypoxia enhanced the brain uptake of3H, but not of either11C or14C. Starvation enhanced the brain uptake of3H...
Source: Annals of Nuclear Medicine - September 30, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Book reviewEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Content Type Journal ArticleDOI 10.1007/BF03165406Authors Keigo Endo, Gunma University, Maebashi 371 Gunma Japan Journal Annals of Nuclear MedicineOnline ISSN 1864-6433Print ISSN 0914-7187 Journal Volume Volume 10 Journal Issue Volume 10, Number 2 / June, 1996 (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - September 30, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Incidental67Ga uptake into an appendiceal mucocele in a patient with sigmoid colon cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a case of sigmoid colon cancer in which visualization of an appendiceal mucocele was unexpectedly found during67Ga scintigraphy, and discuss a proposed mechanism of uptake. Content Type Journal ArticleCategory Case ReportDOI 10.1007/BF03165402Authors Hitoya Ohta, Osaka Red Cross Hospital Department of Laboratories 5-53 Fudegasaki-cho, Tennohji-ku 543 Osaka JapanTomoo Komibuchi, Osaka Red Cross Hospital Department of Laboratories 5-53 Fudegasaki-cho, Tennohji-ku 543 Osaka JapanShoushiro Oe, Osaka Red Cross Hospital Department of Surgery JapanTetsuji Hanafusa, Osaka Red Cross Hospital Department of Surgery Jap...
Source: Annals of Nuclear Medicine - September 30, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Intense and prolonged Tl-201 accumulation in a slow growing bronchioloalveolar carcinomaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Thallium-201 SPECT was performed to evaluate a pulmonary lesion in a 73-year-old male which had been considered to be an inflammatory lesion for two years. The lesion has slowly increased in size on x-CT. Tl-201 was intensely taken up and retained in the lesion, suggesting a malignant lesion. Histological examination revealed that the lesion was bronchioloalveolar carcinoma. This case suggested that Tl-201 uptake of pulmonary carcinoma would not be necessarily related to cell growth rate. Content Type Journal ArticleCategory Case ReportDOI 10.1007/BF03165403Authors Seigo Kinuya, Kanazawa Univers...
Source: Annals of Nuclear Medicine - September 30, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

99mTc-MIBI accumulation in the parathyroid autograft in a patient with recurrent hyperparathyroidismEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract A case with recurrent hyperparathyroidism secondary to chronic renal insufficiency is reported. The patient had undergone total parathyroidectomy and autotransplantation of parathyroid tissue five years ago. Bone scintigraphy clearly demonstrated skeletal involvement of secondary hyperparathyroidism and99mTc-methoxyisobutylisonitrile scintigraphy clearly demonstrated a hyperfunctioning parathyroid autograft. Content Type Journal ArticleCategory Case ReportDOI 10.1007/BF03165400Authors Hitoya Ohta, Osaka Red Cross Hospital Department of Laboratories 5-53 Fudegasaki-cho Tennohji-ku 543 Osaka JapanT...
Source: Annals of Nuclear Medicine - September 30, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Differences between99mTc-DTPA and99mTc-MAG3 captopril renographies in renovascular hypertensionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Captopril renography (CRS) with99mTc-DTPA and99mTc-MAG3 was performed on a 21-year-old woman with renovascular hypertension due to right renal artery stenosis caused by fibromuscular dysplasia. In the affected kidney, the renogram pattern was substantially changed with99mTc-DTPA and99mTc-MAG3 following the administration of captopril, and the quantitated renal uptake indicating individual renal function was significantly decreased in99mTc-DTPA and slightly decreased in99mTc-MAG3. In the contralateral normal kidney, the renogram showed some minor changes with both radioagents, while the quantitated re...
Source: Annals of Nuclear Medicine - September 30, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

A mural thrombus of an infrarenal aortic aneurysm demonstrated as photon deficiency in a radionuclide studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Radionuclide angiogram (RNA) and aortogram may underestimate external aneurysmal diameter. Photon deficient areas are not uncommon along the abdominal aortic aneurysm (AAA) on RNA. To determine whether or not photon deficient areas along the aneurysm could represent a large thrombus, we studied radionuclide aortic angiography in thirty-eight patients during a preoperative cardiac gated study. All the patients (men, ages from 60 to 78) had CT, US, and/or aortogram for comparison. The presence of a thrombus was determined by CT, US, and/or surgical findings. Twelve of 38 (32%) patients’ RNA and bloo...
Source: Annals of Nuclear Medicine - September 30, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Variable kidney position mimicking renal artery branch stenosis in a Tc-99m-DTPA captopril scintigraphyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Tc-99m-DTPA captopril scintigraphy was performed in a patient with suspected renovascular hypertension. Markedly impaired right renal function (Glomerular filtration rate (GFR) values for the right kidney = 14 ml/min, left kidney = 79 ml/min) was detected in the initial captopril study. Only lower pole activity of the right kidney was observed during the whole study. Since prior ultrasonographic examinations have shown bilateral normal kidney parenchyma, branch stenosis of the right upper pole was suspected. Besides significant function improvement in the following baseline study (GFR values for the...
Source: Annals of Nuclear Medicine - September 30, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Tc-99m tetrofosmin myocardial perfusion SPECT after dipyridamole combined with low-level exercise in the diagnosis of coronary artery diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We examined 42 patients and 10 normal volunteers who also underwent coronary angiography. A one-day protocol was used: in the stress study, 296 MBq of tetrofosmin was injected and in the rest study 888 MBq was injected. After intravenous administration of dipyridamole (0.142 mg/kg/min for 4 minutes), the patient was exercised on a bicycle ergometer for 3 min (25 Watts). Tetrofosmin was injected 2 minutes after dipyridamole infusion during the exercise. Single photon emission computed tomographic images were obtained 30 minutes after the tracer injection. Images were interpreted as abnormal in 36 of 42 patients with co...
Source: Annals of Nuclear Medicine - September 30, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals

Myocardial defect detected by123I-BMIPP scintigraphy and left ventricular dysfunction in patients with idiopathic dilated cardiomyopathyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract The present study examined the role of myocardial fatty acid in patients with idiopathic cardiomyopathy (DCM) by means of123I-β-methyl-p-iodophenyl pentadecanoic acid (123I-BMIPP) scintigraphy. Thirteen patients underwent123I-BMIPP imaging,201Tl imaging and echocardiography. All patients showed defective myocardial uptake of123I-BMIPP and201Tl. The left ventricular end-diastolic dimension (64.1 ± 7.3 mm vs. 55.6 ± 1.5 mm, p < 0.05) and end-systolic dimension (52.4 ± 8.0 mm vs. 40.6 ± 2.1 mm, p < 0.01) were significantly larger in the large defect group (123I-BMIPP defect score (DS) > 8) t...
Source: Annals of Nuclear Medicine - September 30, 2009 Category: Radiology Tags: Annals of Nuclear Medicine Source Type: journals