Archives of Oral Biology
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Effect of a dentifrice containing the peptide of streptococcal antigen I/II on the adherence of mutans streptococcus
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The objective of this study was to study the effect of a peptide corresponding to residues 1025–1044 of antigen I/II and a dentifrice containing peptide on the adherence of MS.Methods: The peptide was synthesized and included into dentifrice. Anti-adherence experiments of the peptide and a dentifrice containing it were processed in vitro and in vivo.Results: The results showed that the adherence of MS to hydroxyapatite was inhibited by synthetic antigen I/II peptide and also by a dentifrice containing the peptide in vitro. The numbers of MS in plaque from subjects treated with dentifrices containing the peptide for 1 mon...
Source: Archives of Oral Biology - October 9, 2009 Category: Dentistry Authors: Ming-Yu Li, Jun Wang, Guang-Yun Lai Tags: Microbial biofilms Source Type: journals
The effects of nicotine and cotinine on Porphyromonas gingivalis colonisation of epithelial cellsEmail this article to a colleague.
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Abstract: Smoking is a risk factor for development of periodontitis. Porphyromonas gingivalis is an important colonizer of the subgingival crevice and is a major pathogenic agent in the initiation and progression of severe forms of periodontal disease. However, the effect of major cigarette's derivatives on P. gingivalis is poorly understood. The purpose of this study was to determine the influence of nicotine and cotinine on bacterial colonisation to epithelial cells. KB cells monolayers and P. gingivalis ATCC 33277 were exposed to 0.1, 10 and 100μg/mL of nicotine and cotinine concentrations. The epithelial cells were in...
Source: Archives of Oral Biology - October 9, 2009 Category: Dentistry Authors: Karina Cogo, Bruna Maria Calvi, Flávia Sammartino Mariano, Gilson Cesar Nobre Franco, Reginaldo Bruno Gonçalves, Francisco Carlos Groppo Tags: Microbial biofilms Source Type: journals
Architectural analysis, viability assessment and growth kinetics of Candida albicans and Candida glabrata biofilmsEmail this article to a colleague.
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Abstract: The human fungal pathogen Candida is able to form biofilms in almost all the medical devices in current use. Indeed, biofilm formation is a major virulence attribute of microorganisms and account for a majority of human infections. Therefore, understanding processes appertaining to biofilm development is an important prerequisite for devising new strategies to prevent or eradicate biofilm-related infections. In the present study we used an array of both conventional and novel analytical tools to obtain a comprehensive view of Candida biofilm development. Enumeration of colony forming units, colorimetric (XTT) ass...
Source: Archives of Oral Biology - October 9, 2009 Category: Dentistry Authors: C.J. Seneviratne, W.J. Silva, L.J. Jin, Y.H. Samaranayake, L.P. Samaranayake Tags: Microbial biofilms Source Type: journals
Effect of nonsurgical periodontal therapy on crevicular fluid levels of Cathepsin K in periodontitisEmail this article to a colleague.
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Conclusions: GCF CTSK levels increased in periodontitis and correlated negatively with clinical parameters like GI, PPD and CAL. CTSK levels decreased after nonsurgical treatment of periodontitis. Thus, CTSK can be considered as a ‘marker of osteoclastic activity’ in periodontal disease and also deserves further consideration as a therapeutic target. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - October 9, 2009 Category: Dentistry Authors: Garima Garg, A.R. Pradeep, Manoj Kumar Thorat Tags: Periodontitis Source Type: journals
Functional alterations in mechanical loading of condylar cartilage induces changes in the bony subcondylar regionEmail this article to a colleague.
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Abstract: Bone remodeling is orchestrated by cells of the osteoblast lineage and involves an intricate network of cell–cell and cell–matrix interactions. This dynamic process engages systemic hormones, locally produced cytokines and growth factors, as well as the mechanical environment of the cells. In growing subjects, the mandibular condyle consists of both articular and growth components and the presence of progenitor cells is verified by their anabolic responses to growth hormones. The pathways of chondrocyte and osteoblast differentiation during endochondral bone formation are interconnected and controlled by key ...
Source: Archives of Oral Biology - October 9, 2009 Category: Dentistry Authors: Dionysios J. Papachristou, Katerina K. Papachroni, George A. Papavassiliou, Pertti Pirttiniemi, Vassilis G. Gorgoulis, Christina Piperi, Efthimia K. Basdra Tags: Bone biology Source Type: journals
Effects of phytoestrogen genistein on genioglossus function and oestrogen receptors expression in ovariectomized ratsEmail this article to a colleague.
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Conclusion: The results indicated that genistein increased muscle fatigue resistance in addition to effects on receptors, and the up-regulation of receptors expression may be a possible mechanism by which genistein improved fatigue. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - October 9, 2009 Category: Dentistry Authors: Wen Li, Yue-hua Liu Tags: Muscle biology Source Type: journals
Regional differences in blood flow variation in rat masseter muscleEmail this article to a colleague.
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Abstract: Regions of a belly in a masseter muscle have been suggested to be activated independently in order to enable complex jaw-movements. However a regional difference of the masseter blood flow (MBF) is still unclear although the blood flow is one of the most important factors during activation of the muscle. The present study examined regional differences in blood flow in rat masseter muscle by comparing blood flow values at the inferior, centre, superior, anterior, and posterior regions of the muscle belly using a laser speckle imaging flowmeter with or without sympathetic and parasympathetic stimulation. Regional d...
Source: Archives of Oral Biology - October 9, 2009 Category: Dentistry Authors: Takeharu Niioka, Hisayoshi Ishii, Hiroshi Izumi Tags: Muscle biology Source Type: journals
Regional distribution of interglobular dentine in human teethEmail this article to a colleague.
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This study aimed to find out the regional distribution of IGD in human teeth to observe any association between the extent of OP and the pattern of distribution of IGD.Ground sections were prepared from 52 extracted permanent teeth and the presence of IGD was observed in different regions of the crown and the root.The highest occurrence of IGD was found in the cervical and middle thirds followed by intercuspal, and coronal third in the crown. Statistical analysis of data depicted that the occurrence of IGD differed according to the region of the tooth. In roots, the highest occurrence of IGD was seen in the cervical third ...
Source: Archives of Oral Biology - October 9, 2009 Category: Dentistry Authors: Chantha Jayawardena, Tharanga Nandasena, Anushka Abeywardena, Deepthi Nanayakkara Tags: Tooth biology and development Source Type: journals
Morphological characterization of rat incisor fluorotic lesionsEmail this article to a colleague.
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In conclusion, the white bands of fluorotic rat enamel represent hypomineralized superficial areas and are not subsurface lesions. The detailed description of these lesions is important to understand dental fluorosis. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - October 9, 2009 Category: Dentistry Authors: Regina Aparecida Saiani, Isabel Maria Porto, Elcio Marcantonio Junior, Jaime Aparecido Cury, Frederico Barbosa de Sousa, Raquel Fernanda Gerlach Tags: Tooth biology and development Source Type: journals
Family-with-sequence-similarity-46, member A (Fam46a) gene is expressed in developing tooth budsEmail this article to a colleague.
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Conclusion: We have shown that Fam46a is expressed in ameloblasts’ nuclei of tooth germs and hypothesise that it might act together with morphogenetic factors important for the formation of enamel in mouse tooth. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - October 9, 2009 Category: Dentistry Authors: Godfrey E. Etokebe, Axel M. Küchler, Guttorm Haraldsen, Maria Landin, Harald Osmundsen, Zlatko Dembic Tags: Tooth biology and development Source Type: journals
Effect of fluoride varnish and gel on dental erosion in primary and permanent teethEmail this article to a colleague.
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Abstract: Objective: To assess the effect of a fluoride varnish and gel on the erosive wear of primary and permanent teeth.Design: Sixty human primary (n=30) and permanent (n=30) enamel specimens were randomly assigned to one of the following groups: APF gel (1.23% F), NaF varnish (2.26% F), and control (no treatment). Fluoride gel was applied for 4min and fluoride varnish for 24h. Six daily demineralisation–remineralization cycles of 5min of immersion in a cola drink (pH 2.3) and 30min in artificial saliva were conducted during 7 days. All specimens were stored in artificial saliva between and after cycles. Surface Knoo...
Source: Archives of Oral Biology - October 9, 2009 Category: Dentistry Authors: Christiana Murakami, Marcelo Bönecker, Maria Salete Nahás Pires Corrêa, Fausto Medeiros Mendes, Célia Regina Martins Delgado Rodrigues Tags: Tooth biology and development Source Type: journals
Activation of the extrinsic apoptotic pathway by TNF-α in Human Salivary Gland (HSG) cells in vitro, suggests a role for the TNF receptor (TNF-R) and Intercellular Adhesion Molecule-1 (ICAM-1) in Sjögren's Syndrome-associated autoimmune sialadenitisEmail this article to a colleague.
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Conclusion: The apoptotic pathway controls morphological, structural and functional properties of apoptotic bodies. Collectively, TNF-α-dependent activation of the extrinsic apoptotic pathway leads to upregulation of ICAM-1 and CCL20 in HSG in vitro. This suggests that pathogenesis in Sjögren's Syndrome may involve a TNF-controlled cross-talk between apoptotic ductal and CCL20-attracted dendritic cells via the CD137/CD137L signalling pathway. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - October 9, 2009 Category: Dentistry Authors: Yan Wang, Alexander Shnyra, Charlene Africa, Christopher Warholic, Carole McArthur Tags: Saliva and salivary glands Source Type: journals
Availability of saliva for the assessment of alterations in the autonomic nervous system caused by physical exercise trainingEmail this article to a colleague.
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Conclusion: Physical exercise under diet control induced alterations in saliva secretion, while exercise training alone did not affect the content of saliva. The results demonstrate the availability of saliva and suggest that the present experimental situation is a suitable experimental model for sports activity performed under diet control. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - October 9, 2009 Category: Dentistry Authors: Yoko Yoshino, Akira Yamane, Masashige Suzuki, Yoichi Nakagawa Tags: Saliva and salivary glands Source Type: journals
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(Source: Archives of Oral Biology)
Source: Archives of Oral Biology - October 9, 2009 Category: Dentistry Source Type: journals
Stimulated saliva flow rate patterns in children: A six-year longitudinal studyEmail this article to a colleague.
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Conclusions: These findings indicate that a high or low SSFR is a constant individual trait in children. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - September 7, 2009 Category: Dentistry Authors: Sánchez-Pérez Leonor, Saénz-Martínez Laura, Irigoyen-Camacho Esther, Zepeda-Zepeda Marco, Acosta-Gío A. Enrique, Méndez-Ramírez Ignacio Tags: Saliva and salivary glands Source Type: journals
Influences of interferon-gamma on cell proliferation and interleukin-6 production in Down syndrome derived fibroblastsEmail this article to a colleague.
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Conclusion: Taken together, our results are consistent with hypersensitive reactions to IFN-γ seen in patients with Down syndrome and may provide useful information to elucidate the mechanisms of IFN-γ activities in those individuals. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - September 7, 2009 Category: Dentistry Authors: Tsutomu Iwamoto, Aya Yamada, Kenji Yuasa, Emiko Fukumoto, Takashi Nakamura, Taku Fujiwara, Satoshi Fukumoto Tags: Fibroblast function Source Type: journals
The transmembrane transport of metformin by osteoblasts from rat mandibleEmail this article to a colleague.
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In this study, the osteoblasts from rat mandible were cultured with 5.5mM (control) or 16.5mM d-glucose, then the uptake of metformin by osteoblasts was detected with high performance liquid chromatography (HPLC). Rat organic cation transporter (rOct) expression was characterized by immunocytochemistry, RT-PCR and Western blotting. It was found that, the uptake of metformin was saturable, Na+-dependent, affected by extracellular pH and inhibited by both phenformin and cimetidine (an inhibitor of Octs). rOct1 but no rOct2 was expressed extensively in osteoblasts and the protein level of rOct1 could be up-regulated by metfor...
Source: Archives of Oral Biology - September 7, 2009 Category: Dentistry Authors: Long Ma, Xia Wu, E. Ling-Ling, Dong-Sheng Wang, Hong-Chen Liu Tags: Tissue engineering and bone biology Source Type: journals
Recombinant adeno-associated virus serotype 2 (rAAV2)—An efficient vector for gene delivery in condylar cartilage, glenoid fossa and TMJ disc in an experimental study in vivoEmail this article to a colleague.
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Conclusion: Recombinant AAV2 could be considered as a promising vector for gene therapy in TMJ which can mediate therapeutic gene expression in glenoid fossa, articular disc and condylar cartilage in vivo. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - September 7, 2009 Category: Dentistry Authors: Qianfeng Li, Juan Dai, A. Bakr. M. Rabie Tags: Tissue engineering and bone biology Source Type: journals
Up-regulation of vascular endothelial growth factor expression by adenosine through adenosine A2 receptors in the rat tongue treated with endotoxinEmail this article to a colleague.
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Abstract: The main focus of the present investigation is to evaluate a differential effect of adenosine on the up-regulation of vascular endothelial growth factor (VEGF) expression through adenosine A2 receptors in the rat tongue treated with endotoxin (lipopolysaccharide: LPS). Angiogenesis in the rat tongue treated with LPS/incomplete Freund's adjuvant (IFA) or endotoxin/IFA/adenosine A2 receptor (A2R) antagonists was examined using immunohistochemistry for LYVE-1, ED1, ED2, OX6, langerin and VEGF, and real-time polymerase chain reaction (PCR) for VEGF. The distributional density of both blood vessels and OX6+ cells was ...
Source: Archives of Oral Biology - September 7, 2009 Category: Dentistry Authors: Yaiko Hara, Noriyuki Kuroda, Kouji Inoue, Tetsuji Sato Tags: Oral epithelial biology and cancer Source Type: journals
Cancer progression is associated with increased expression of basement membrane proteins in three-dimensional in vitro models of human oral cancerEmail this article to a colleague.
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Conclusions: These findings, obtained in a 3D in vitro model that closely mirrors the in vivo human oral cancer progression, show an enhanced basement membrane protein expression during human oral cancer progression that is dependent on the epithelial–mesenchymal environment, respectively the existence of fibroblasts. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - September 7, 2009 Category: Dentistry Authors: Keerthi K. Kulasekara, Ochiba M. Lukandu, Evelyn Neppelberg, Olav K. Vintermyr, Anne Christine Johannessen, Daniela Elena Costea Tags: Oral epithelial biology and cancer Source Type: journals
Cyclin D1 expression and its possible regulation in chewing tobacco mediated oral squamous cell carcinoma progressionEmail this article to a colleague.
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Abstract: Objective: Proto-oncogene cyclin D1 is a G1 phase specific cell cycle regulator and known for its role in various cancers. The aim of the study was to understand oral cancer progression by observing the mRNA and protein expression of cyclin D1.Methods: Different oral tissue samples were selected as a model to study oral cancer progression. Those include healthy oral mucosa, premalignant lesions (Leukoplakia, Erythroplakia, Oral SubMucous Fibrosis) and oral cancer (OSCC) samples. Cyclin D1 mRNA and protein expression were detected by slot-blot and by immunohistochemical methods, respectively.Results: Premalignant ...
Source: Archives of Oral Biology - September 7, 2009 Category: Dentistry Authors: Rajakishore Mishra, Bibhu Ranjan Das Tags: Oral epithelial biology and cancer Source Type: journals
Involvement of vasoactive intestinal polypeptide in the parasympathetic vasodilatation of the rat masseter muscleEmail this article to a colleague.
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Abstract: The parasympathetic vasodilatory fibres are known to innervate vessels in a rat masseter muscle via both cholinergic and non-cholinergic mechanisms. However, the non-cholinergic mechanisms are still unclear. Recently, vasoactive intestinal polypeptide (VIP) was convincingly shown to be involved in the parasympathetic vasodilatation in orofacial areas, such as submandibular glands and lower lip. However, very little is known about the rat masseter muscle. The present study was designed in the rat masseter muscle to assess (1) whether the parasympathetic nerve innervating vessels have VIP immunoreactivities, (2) wh...
Source: Archives of Oral Biology - September 7, 2009 Category: Dentistry Authors: Takeharu Niioka, Hisayoshi Ishii, Hiroshi Izumi Tags: Masseter muscle blood flow Source Type: journals
Phenotype and behaviour of dental pulp cells during expansion cultureEmail this article to a colleague.
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Conclusions: The present study characterizes conditions for primary pulp cell isolation and expansion and indicates that both earlier and later passages maintain differentiation capacity. Continued passage however may result in selection for cells with a pericyte/myofibroblast phenotype. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - September 7, 2009 Category: Dentistry Authors: Minal Patel, Anthony J. Smith, Alastair J. Sloan, Gay Smith, Paul R. Cooper Tags: Tooth pulp biology Source Type: journals
Methylation frequencies of cell-cycle associated genes in epithelial odontogenic tumoursEmail this article to a colleague.
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Conclusions: Epithelial odontogenic tumours show a distinct methylation profile in cell-cycle associated genes. In addition to this, the current findings show that epigenetic alterations are common events in epithelial odontogenic tumours. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - September 7, 2009 Category: Dentistry Authors: Paula Rocha Moreira, Mariana Moreira Guimarães, Carolina Cavaliéri Gomes, Marina Gonçalves Diniz, João Artur Ricieri Brito, Wagner Henriques de Castro, Ricardo Santiago Gomez Tags: Tooth development and odontogenic tumours Source Type: journals
Expression of typical calpains in mouse molarEmail this article to a colleague.
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Conclusions: In this study the temporal transition of calpain1, calpain2 and calpastatin mRNA and the immunolocalization are identified during tooth development. Our results indicate that the calcium-dependent proteases may play an important role in mouse molar development and extracellular calpain and calpastatin may be involved in molar mineralization. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - September 7, 2009 Category: Dentistry Authors: T. Matsunaga, G. Yamamoto, T. Tachikawa Tags: Tooth development and odontogenic tumours Source Type: journals
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(Source: Archives of Oral Biology)
Source: Archives of Oral Biology - September 7, 2009 Category: Dentistry Source Type: journals
Reproducible effects of subjectively assessed muscle fatigue on an inhibitory jaw reflex in humansEmail this article to a colleague.
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Abstract: Objective: To evaluate the effects of exercise-induced, subjectively assessed muscle fatigue on an inhibitory jaw reflex, evoked by electrical stimulation of the upper lip. In addition, the reproducibility of these effects was assessed.Design: Eight subjects participated in two experimental sessions that were two weeks apart. During each session, a baseline recording, a post-conditioning recording, and two recovery recordings were obtained. The post-conditioning recording was obtained immediately after provocation of jaw muscle fatigue by intense chewing. The endpoint of provocation was reached 30s after a subjec...
Source: Archives of Oral Biology - July 28, 2009 Category: Dentistry Authors: Nicoline C.W. van der Kaaij, Pauline Maillou, Jacobus J. van der Weijden, Machiel Naeije, Frank Lobbezoo Tags: Jaw muscle function Source Type: journals
Immunohistochemical detection of nerve growth factor and its receptors in the rat periodontal ligament during tooth movementEmail this article to a colleague.
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Conclusion: Data suggest that orthodontic injury induces NGF production, leading to sprouting and invasion by CGRP-positive nerve fibers and that injection of anti-NGF reduces NGF tissue levels and prevents innervation by CGRP-positive fibers. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - July 28, 2009 Category: Dentistry Authors: Akbar H. O’Hara, Wayne J. Sampson, Craig W. Dreyer, Angela M. Pierce, Ian A. Ferguson Tags: Periodontal ligament Source Type: journals
Cyclic stretching force induces apoptosis in human periodontal ligament cells via caspase-9Email this article to a colleague.
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Abstract: The response of periodontal ligament (PDL) cells to mechanical stimulation is important in the periodontal tissue remodelling. Our previous study showed that cyclic stretching force on PDL cells induced early apoptosis. However, the mechanism of stretching force-induced cell death is unclear. In the present study, we examined whether PDL cells undergo apoptosis by stretching force using the terminal deoxynucleotidyl transferase (TdT)-mediated dUTP-biotin nick-end-labellling method (TUNEL) and investigated the mechanism by which cyclic stretching force initiated apoptosis. We found that PDL cells became aligned re...
Source: Archives of Oral Biology - July 28, 2009 Category: Dentistry Authors: Yi Hao, Chun Xu, Shu-yang Sun, Fu-qiang Zhang Tags: Periodontal ligament Source Type: journals
Periodontal histomorphometry and status of aged sheep subjected to ovariectomy, malnutrition and glucocorticoid applicationEmail this article to a colleague.
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Conclusions: Together these findings suggest that in sheep, the cumulating effects of ageing, hypogonadism, malnutrition and glucocorticoid application can cause substantial catabolic changes of the periodontium. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - July 28, 2009 Category: Dentistry Authors: G. Dvorak, K. Reich, S. Tangl, C.A. Lill, M. Gottschalk-Baron, G. Watzek, R. Gruber, R. Haas Tags: Periodontal ligament Source Type: journals
Zoledronic acid decreases bone formation without causing osteocyte death in miceEmail this article to a colleague.
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Abstract: Bisphosphonates have been associated with osteonecrosis of the jaw. The purpose of this study was to examine the effect of a potent bisphosphonate, zoledronic acid (ZA) on osteocyte viability and bone formation. Ten experimental C57BL/6 mice were administered ZA (0.1mg/kg-i.p.) weekly for 9 weeks while four control mice did not receive the drug. A pair of calcein (30mg/kg) labels was administered 10 and 3 days prior to sacrifice of the 34-week-old mice. Fresh mandibular and femoral sections were obtained to evaluate osteocyte viability using a lactate dehydrogenase (LDH) assay. In addition, sections from the femu...
Source: Archives of Oral Biology - July 28, 2009 Category: Dentistry Authors: S.S. Huja, S.A. Fernandez, Christina Phillips, Y. Li Tags: Osteogenesis Source Type: journals
Expression patterns of the Fam83h gene during murine tooth developmentEmail this article to a colleague.
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Conclusion: Fam83h was detected in the ameloblasts from the presecretory to the secretory stage, and also the odontoblasts layer and surrounding alveolar bone. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - July 28, 2009 Category: Dentistry Authors: Min-Jung Lee, Sook-Kyung Lee, Kyung-Eun Lee, Hee-Yun Kang, Han-Sung Jung, Jung-Wook Kim Tags: Tooth development Source Type: journals
Influence of ADAM28 on biological characteristics of human dental follicle cellsEmail this article to a colleague.
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Conclusions: ADAM28 might actively participate in the network regulation which associates HDFCs proliferation, differentiation, apoptosis with matrix mineralisation during tooth development by interacting with multiple signal molecules. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - July 28, 2009 Category: Dentistry Authors: Zheng Zhao, Hongchen Liu, Yan Jin, E. Lingling Tags: Tooth development Source Type: journals
Thickness and microhardness of deciduous tooth enamel with known DLX3 mutationEmail this article to a colleague.
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Conclusion: This study shows that enamel affected by a 2-bp deletion in DLX3 has reduced thickness as well as diminished microhardness. These data may explain the severe attrition and interdental spacing observed in affected individuals. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - July 28, 2009 Category: Dentistry Authors: Hong-Keun Hyun, Jung-Wook Kim Tags: Tooth mineralization Source Type: journals
Influence of fluoride concentration and ethanol pre-treatment on the reduction of the acid susceptibility of enamelEmail this article to a colleague.
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Abstract: Objective: To determine the association between KOH-soluble and structurally bound fluoride uptake and the erosion resistance of enamel, respectively. Additionally, the effect of enamel pre-treatment with ethanol before fluoridation was assessed.Methods: Sixty bovine incisors (4 specimens/tooth) were randomly allocated to six groups (A–F). Samples 1 and 2 remained untreated, serving as control at baseline. Pre-treatment of the samples was performed for 5min with 99% ethanol (groups A, B and C) or physiologic saline (groups D, E and F). Samples 3 and 4 were treated either with 0.5% (groups A and D), 1.0% (groups...
Source: Archives of Oral Biology - July 28, 2009 Category: Dentistry Authors: Florian J. Wegehaupt, Barbara Solt, Beatrice Sener, Annette Wiegand, Patrick R. Schmidlin, Thomas Attin Tags: Tooth mineralization Source Type: journals
Effects of Galla chinensis on inhibition of demineralization of regular bovine enamel or enamel disposed of organic matrixEmail this article to a colleague.
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Abstract: Objective: This in vitro study was undertaken to assess the effects of Galla chinensis extract on inhibition of enamel caries-like demineralization and to elucidate the role of the organic matrix of enamel in this process.Design: Either regular or enamel disposed of its organic matrix both of bovine origin were exposed to a demineralizing solution for 3 days (pH 4.5). Specimes were additionally treated with either 4g/L of G. chinensis extraction (GCE) or double distilled water (DDW) four times daily for 5min each time. Regular enamel exposed accordingly to sodium fluoride (1g/L) during the demineralizing period s...
Source: Archives of Oral Biology - July 28, 2009 Category: Dentistry Authors: Linglin Zhang, Jing Xue, Jiyao Li, Ling Zou, Yuqing Hao, Xuedong Zhou, Wei Li Tags: Tooth mineralization Source Type: journals
Evaluation of the remineralising capacities of modified saliva substitutes in vitroEmail this article to a colleague.
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Abstract: Objective: In this in vitro study the effects of various calcium and phosphate additions to a commercially available saliva substitute on remineralisation of demineralised dentin were investigated.Design: Bovine dentin specimens (n=70) were prepared. Before and after demineralisation (37°C, pH 5.0, 5 days), one-quarter of each specimens surface was covered with nail varnish (control sound/demineralised tissue). Specimens were exposed either to original Saliva natura (SN 0) or to three modified versions (SN 1, SN 2 and SN 3) formulated with different degrees of saturation with respect to octacalciumphosphate (OCP...
Source: Archives of Oral Biology - July 28, 2009 Category: Dentistry Authors: P. Tschoppe, A.M. Kielbassa, H. Meyer-Lueckel Tags: Tooth mineralization Source Type: journals
SELDI–TOF-MS of gingival crevicular fluid—A methodological approachEmail this article to a colleague.
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Abstract: Human neutrophil peptides (HNPs) and the human cathelicidin LL-37 are antimicrobial peptides secreted by neutrophils, which play a crucial role in innate immune responses. The aim of this study was to establish a new method for ProteinChip® arrays in combination with surface enhanced laser desorption/ionization (SELDI) technology and time-of-flight mass spectrometry to analyze gingival crevicular fluid (GCF) samples. To optimize experimental conditions, four different ProteinChip® arrays (NP20; CM10, pH 4; CM10, pH 7; IMAC) along with corresponding binding buffers were tested. GCF samples were collected from pa...
Source: Archives of Oral Biology - July 28, 2009 Category: Dentistry Authors: H. Dommisch, S. Vorderwülbecke, J. Eberhard, M. Steglich, S. Jepsen Tags: Saliva and crevicular fluid Source Type: journals
Salivary levels of IL-1β, IL-6, IL-8, and TNF-α in patients with burning mouth syndromeEmail this article to a colleague.
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Conclusion: There were no differences in the salivary levels of IL-1β, IL-6, IL-8, and TNF-α in BMS patients compared with controls. Cytokine levels in whole saliva were affected mainly by the amount of blood contamination. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - July 28, 2009 Category: Dentistry Authors: Kyung-Im Suh, Young-Ku Kim, Hong-Seop Kho Tags: Saliva and crevicular fluid Source Type: journals
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(Source: Archives of Oral Biology)
Source: Archives of Oral Biology - July 28, 2009 Category: Dentistry Source Type: journals
TiF4 and NaF at pH 1.2 but not at pH 3.5 are able to reduce dentin erosionEmail this article to a colleague.
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Conclusion: Dentin erosion can be significantly reduced by TiF4 and NaF at pH 1.2, but not at pH 3.5. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - June 25, 2009 Category: Dentistry Authors: Annette Wiegand, Ana Carolina Magalhães, Beatrice Sener, Elena Waldheim, Thomas Attin Tags: Dentin erosion Source Type: journals
Effects of increased occlusal vertical dimension on daily activity and myosin heavy chain composition in rat jaw muscleEmail this article to a colleague.
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Abstract: Mammalian skeletal muscles change their contractile-protein phenotype in response to mechanical loading and/or chronic electrical stimulation, implying that the phenotypic changes in masticatory muscles might result from new masticatory-loading conditions. To analyze the effects of increased occlusal vertical dimension (OVD) on daily activities and fibre-type compositions in jaw muscles, we measured the total duration of daily activity (duty time) and the myosin heavy chain (MyHC) compositions in the masseter and digastric muscles of freely moving control and bite-opened rats. In the control state, the duty time ...
Source: Archives of Oral Biology - June 25, 2009 Category: Dentistry Authors: Yoshiki Ohnuki, Nobuhiko Kawai, Eiji Tanaka, Geerling E.J. Langenbach, Kazuo Tanne, Yasutake Saeki Tags: Jaw muscles Source Type: journals
Jaw and hyolingual muscle activity patterns and bite forces in the herbivorous lizard Uromastyx acanthinurusEmail this article to a colleague.
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Abstract: Uromastyx lizards are basal agamid lizards that are characterized by an herbivorous diet and a robust akinetic skull. Recently, lizards in general, and Uromastyx lizards in particular, have become a model system for mechanical analyses of skull function. However, quantitative models of skull function are hampered by a lack of knowledge on the activation patterns of jaw and hyolingual muscles. Moreover, in vivo bite force or strain data, essential to test the validity of these modelling efforts, are lacking. Here we provide data on the muscle activation patterns and bite forces in the lizard Uromastyx acanthinurus...
Source: Archives of Oral Biology - June 25, 2009 Category: Dentistry Authors: Anthony Herrel, Frits De Vree Tags: Jaw muscles Source Type: journals
Immunolocalization of matrix metalloproteinases-2 and -9 during apical periodontitis developmentEmail this article to a colleague.
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Conclusion: The results observed in this study suggest that MMP-2 and MMP-9 play a critical role in the development of inflammatory periapical lesions, probably involved in the extracellular matrix (ECM) degradation during the initial phase of the lesion development. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - June 25, 2009 Category: Dentistry Authors: Mauro V. Corotti, Willian F. Zambuzzi, Katiúcia B.S. Paiva, Renato Menezes, Lidiane C. Pinto, Vanessa S. Lara, José M. Granjeiro Tags: Periodontitis Source Type: journals
Effects of hyaluronan oligosaccharide on the expression of MMP-1 in periodontal ligament cellsEmail this article to a colleague.
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In this study, we investigated the effect of HAoligo on MMP-1 expression in human PDL (HPDL) cells and the mechanisms in terms of the signal transmission. HAoligo was generated and purified from commercial human umbilical cord HA. HPDL cells were isolated from healthy ligaments, and cultured with HAoligo for 0–24h. The expression of MMP-1, tissue inhibitor of MMPs (TIMP)-1 and TIMP-2 was analyzed by real-time PCR and Western blot analyses. Effects of specific inhibitors of p38 mitogen-activated protein kinase (MAPK) activity, MAPK kinase activity and NFkB activity on HAoligo-induced MMP-1 expression in HPDL cells were al...
Source: Archives of Oral Biology - June 25, 2009 Category: Dentistry Authors: Yuki Nakatani, Kotaro Tanimoto, Nobuaki Tanaka, Yuki Tanne, Takashi Kamiya, Ryo Kunimatsu, Eiji Tanaka, Kazuo Tanne Tags: Periodontitis Source Type: journals
Trehalose inhibits inflammatory cytokine production by protecting IκB-α reduction in mouse peritoneal macrophagesEmail this article to a colleague.
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Conclusion: These results may suggest that trehalose inhibits LPS-induced production of IL-1β and TNF-α in mouse peritoneal macrophages by inhibiting degradation of IκB-α via the trehalose receptor T1R3. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - June 25, 2009 Category: Dentistry Authors: Kahoru Taya, Kimiharu Hirose, Setsuo Hamada Tags: Periodontitis Source Type: journals
Anabolic effects of low-intensity pulsed ultrasound on human gingival fibroblastsEmail this article to a colleague.
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Conclusion: LIPUS treatment at 30mW/cm2 selectively enhanced HGF differentiation but not proliferation. The ability of LIPUS to enhance HGF differentiation is promising for its application in cell-based periodontal therapy. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - June 25, 2009 Category: Dentistry Authors: Nesrine Z. Mostafa, Hasan Uludağ, Douglas N. Dederich, Michael R. Doschak, Tarek H. El-Bialy Tags: Gingival metabolism Source Type: journals
Influence of gender on the metabolism of alcohols in human saliva in vitroEmail this article to a colleague.
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Conclusion: No gender difference in the metabolism of 2-propanol and ethanol in human saliva in vitro were found. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - June 25, 2009 Category: Dentistry Authors: Lena Ernstgård Tags: Salivary glands and saliva Source Type: journals
Influence of antidepressant drugs on Ecto-nucleotide pyrophosphatase/phosphodiesterases (E-NPPs) from salivary glands of ratsEmail this article to a colleague.
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In this study, we have evaluated the effect of three different antidepressants in ecto-nucleotide pyrophosphatase/phosphodiesterase (E-NPP1–3) activities in cultured cells from salivary glands. Rats received imipramine (10mg/ml), fluoxetine (20mg/ml) or moclobemide (30mg/ml) by oral gavage. The drugs were administered once a day for 14 days. Our results have shown that the hydrolysis of p-nitrophenyl-5′-thymidine monophosphate increased in all treatments. These effects were not consequence of transcriptional control of E-NPP1–3 genes. The results reported here can highlight the importance of ectonucleotidases in the ...
Source: Archives of Oral Biology - June 25, 2009 Category: Dentistry Authors: Sandra Liana Henz, Giana de Paula Cognato, Fernanda Cenci Vuaden, Maurício Reis Bogo, Carla Denise Bonan, João José Freitas Sarkis Tags: Salivary glands and saliva Source Type: journals
A single application of hydrogen sulphide induces a transient osteoclast differentiation with RANKL expression in the rat modelEmail this article to a colleague.
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Conclusions: H2S application caused a transient increase of osteoclast differentiation with up-regulation of RANKL expression in osteoblasts. H2S, which is primarily responsible for halitosis, may also contribute to alveolar bone resorption through RANKL expression. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - June 25, 2009 Category: Dentistry Authors: Koichiro Irie, Daisuke Ekuni, Tatsuo Yamamoto, Manabu Morita, Ken Yaegaki, Hisataka Ii, Toshio Imai Tags: Bone biology Source Type: journals
