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168 records returned

Chemical profile of Plomin Bay sediments.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Granulometric, chemical, and leaching properties of sediments dredged in the Plomin Bay (Northern Adriatic Sea, Croatia) were investigated in order to asses the risk of remobilisation of heavy metals into the water column. In total 65 samples from 65 sampling sites were taken from different sediment depths within the bay. Analysis of variance confirmed the homogeneity of granulometric and elemental composition of the investigated sediment throughout its volume. Granulometric analysis showed that all samples corresponded to a pelitic fraction (<0.063 mm). Bulk elemental mass fractions in the sediments were similar to...
Source: Arhiv za Higijenu Rada i Toksikologiju - August 31, 2009 Category: Occupational Health Authors: Orescanin V, Nad K, Bartolincić A, Valković V Tags: Arh Hig Rada Toksikol Source Type: journals

In vitro genotoxicity of wastewaters from the town of Settat, Morocco.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study demonstrated significant pollution of Boumoussa valley groundwater and of the local wells. Sampled water induced a clear increase in the frequency of micronucleated cells and a lower cell proliferation in human peripheral blood lymphocytes in vitro. PMID: 19789158 [PubMed - in process] (Source: Arhiv za Higijenu Rada i Toksikologiju)
Source: Arhiv za Higijenu Rada i Toksikologiju - August 31, 2009 Category: Occupational Health Authors: El Asslouj J, Amahdar L, Glouib K, Kholtei S, El Amrani Paaza N, Verschaeve L, Hilali A Tags: Arh Hig Rada Toksikol Source Type: journals

Comparison of ethanol and acetaldehyde toxicity in rat astrocytes in primary culture.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study compared the effects of toxicity of ethanol and its first metabolite acetaldehyde in rat astrocytes through cell viability and cell proliferation. The cells were treated with different concentrations of ethanol in the presence or absence of a catalase inhibitor 2-amino-1,2,4 triazole (AMT) or with different concentrations of acetaldehyde. Cell viability was assessed using the trypan blue test. Cell proliferation was assessed after 24 hours and after seven days of exposure to either ethanol or acetaldehyde.We showed that both ethanol and acetaldehyde decreased cell viability in a dose-dependent manner. In prolife...
Source: Arhiv za Higijenu Rada i Toksikologiju - August 31, 2009 Category: Occupational Health Authors: Sarc L, Lipnik-Stangelj M Tags: Arh Hig Rada Toksikol Source Type: journals

Comet assay in evaluating DNA damage associated with ischaemia-reperfusion injury in patients undergoing coronary surgery.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Ischaemia-reperfusion (I/R) injury is responsible for a number of conditions such as coronary bypass and myocardial infarction, and deaths. Oxygen-free radicals formed during I/R have been proposed as the leading causes of tissue injury, and they play an important role in I/R injury. I/R induces oxidative DNA damage (such as purinic and pyrimidinic base lesions). Comet assay is a suitable and sensitive method for early detection of low-level DNA damage. We used modified alkaline comet assay in peripheral blood lymphocytes and evaluated I/R-induced DNA damage in patients undergoing coronary artery bypass graft (CABG) op...
Source: Arhiv za Higijenu Rada i Toksikologiju - August 31, 2009 Category: Occupational Health Authors: Karahalil B, Gumus T, Emerce E, Izdes S, Kanbak O, Kesimci E Tags: Arh Hig Rada Toksikol Source Type: journals

Potentiation of bleomycin lethality in HeLa and V79 cells by bee venom.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study investigated possible growth-inhibiting effects of bee venom applied alone or in combination with a cytotoxic drug bleomycin on HeLa and V79 cells in vitro based on clone formation, cell counting, and apoptosis. Melittin, the key component of bee venom, is a potent inhibitor of calmodulin activity, and also a potent inhibitor cell growth and clonogenicity. Intracellular accumulation of melittin correlates with the cytotoxicity of antitumour agents. Previous studies indicated that some calcium antagonists and calmodulin inhibitors enhanced intracellular levels of antitumor agents by inhibiting their outward trans...
Source: Arhiv za Higijenu Rada i Toksikologiju - August 31, 2009 Category: Occupational Health Authors: Orsolić N Tags: Arh Hig Rada Toksikol Source Type: journals

Effects of passive smoking at work on respiratory symptoms, lung function, and bronchial responsiveness in never-smoking office cleaning women.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study provides evidence of adverse respiratory effects in office cleaning women associated with passive smoking in the workplace. Our findings support a stricter implementation of the current national law to protect respiratory health of all workers. PMID: 19789162 [PubMed - in process] (Source: Arhiv za Higijenu Rada i Toksikologiju)
Source: Arhiv za Higijenu Rada i Toksikologiju - August 31, 2009 Category: Occupational Health Authors: Minov J, Karadzinska-Bislimovska J, Vasilevska K, Risteska-Kuc S, Stoleski S Tags: Arh Hig Rada Toksikol Source Type: journals

Effects of traffic noise on sleep in an urban population.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Urban noise is an important environmental stressor, and sleep disturbance is its major health effect. Substantial inter-individual variance in these effects might partly be explained by different sensitivity to noise. The aim of this study was to assess the effects of urban noise on sleep and the relation between self-estimated sensitivity to noise and sleep disturbance. A cross-sectional questionnaire survey was performed on 911 adult residents of Nis, Serbia, of whom 388 were men (42.6 %) and 523 women (57.4 %). The streets were regarded as noisy if night equivalent noise level (Leq) was higher than 45 dB(A) and quie...
Source: Arhiv za Higijenu Rada i Toksikologiju - August 31, 2009 Category: Occupational Health Authors: Stosić L, Belojević G, Milutinović S Tags: Arh Hig Rada Toksikol Source Type: journals

Workplace noise exposure after modernisation of an aluminium processing complex.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The aim of this study was to assess to which extent modernisation of an aluminium production complex reduced occupational noise hazard for jobs with the highest potential of exposure. Periodical measurements of noise level were taken at the same workplaces using the same method, before and after modernisation of all plants. The results were compared with the recommended standard. After modernisation, the noise was significantly reduced in all sections of all plants. The greatest reduction was measured in the foundry. After modernisation, the portion of workplaces with excessive noise level dropped significantly (chisqu...
Source: Arhiv za Higijenu Rada i Toksikologiju - August 31, 2009 Category: Occupational Health Authors: Doko-Jelinić J, Lukić J, Udovicić R, Zuskin E, Nola IA, Zajec Z Tags: Arh Hig Rada Toksikol Source Type: journals

Environmental noise and annoyance in adult population of skopje: a cross-sectional study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study has shown that environmental noise is a significant hazard in urban environments, and assessment of annoyance may prove a useful tool for town planners and public health policy makers. PMID: 19789165 [PubMed - in process] (Source: Arhiv za Higijenu Rada i Toksikologiju)
Source: Arhiv za Higijenu Rada i Toksikologiju - August 31, 2009 Category: Occupational Health Authors: Ristovska G, Gjorgjev D, Polozhani A, Kocubovski M, Kendrovski V Tags: Arh Hig Rada Toksikol Source Type: journals

Nitrofurantoin-induced acute liver damage in pregnancy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article presents a rare case of acute toxic hepatitis in thirty-one-year old primigravida. In the 36th week of gestation, the patient was introduced nitrofurantoin 100 mg a day due to symptoms of dysuria and enterococcus isolated from urine culture. After induced delivery at term because of hypertension, repeated laboratory findings showed increased aspartate aminotransferase (AST) and alanine aminotransferase (ALT) and negative hepatitis C and B markers. The patient was subicteric at the time. Coagulation and complete blood count values were within the normal range. Nitrofurantoin therapy was discontinued. Abdominal ...
Source: Arhiv za Higijenu Rada i Toksikologiju - August 31, 2009 Category: Occupational Health Authors: Aksamija A, Horvat G, Habek D, Zalac D, Jendris E Tags: Arh Hig Rada Toksikol Source Type: journals

[Sex hormones and cognitive functioning of women]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This paper discusses the organisational and activational effects of sex hormones, and their influence on cognitive functioning. Previous studies have shown gender differences in specific cognitive abilities. Women generally show an advantage in verbal fluency, perceptual speed and accuracy, as well as in fine motor skills, while men generally show an advantage in spatial and mathematical abilities. These differences in cognitive functioning are thought to occur as a result of foetal brain exposure to different levels of sex hormones during prenatal life. Additional evidence of organisational effects of sex hormones on ...
Source: Arhiv za Higijenu Rada i Toksikologiju - August 31, 2009 Category: Occupational Health Authors: Simić N, Gregov L Tags: Arh Hig Rada Toksikol Source Type: journals

[Human lifespan: to live and outlive 100 years?]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article mentions a few individuals who outlived 100 years in the world, Croatia, and neighbouring countries. Although some argue that the limits of human life cannot be extended over the age of 120 years, for now we cannot predict the actual limits of human life. PMID: 19789168 [PubMed - in process] (Source: Arhiv za Higijenu Rada i Toksikologiju)
Source: Arhiv za Higijenu Rada i Toksikologiju - August 31, 2009 Category: Occupational Health Authors: Roksandić ST, Zuskin E, Duraković Z, Smolej-Narancić N, Mustajbegović J, Pucarin-Cvetković J, Duraković MM, Jelinić JD, Turcić N, Milosević M Tags: Arh Hig Rada Toksikol Source Type: journals

Report of the Poison Control Centre for the period 1 January-31 December 2008.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19588596 [PubMed - in process] (Source: Arhiv za Higijenu Rada i Toksikologiju)
Source: Arhiv za Higijenu Rada i Toksikologiju - May 31, 2009 Category: Occupational Health Authors: Varnai VM, Ljubicić Calusić A, Sabolić-Pipinić I, Macan J, Turk R Tags: Arh Hig Rada Toksikol Source Type: journals

[In process citation]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19588598 [PubMed - in process] (Source: Arhiv za Higijenu Rada i Toksikologiju)
Source: Arhiv za Higijenu Rada i Toksikologiju - May 31, 2009 Category: Occupational Health Authors: Piasek M Tags: Arh Hig Rada Toksikol Source Type: journals

Radioprotective effects of quercetin and ethanolic extract of propolis in gamma-irradiated mice.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The aim of this study was to assess radioprotective effects of quercetin and the ethanolic extract of propolis (EEP) in CBA mice exposed to a single radiation dose 4 Gy (60Co). The mice were treated with 100 mg kg-1 quercetin or EEP a day for three consecutive days either before (pre-treatment) or after gamma-irradiation (therapy). Leukocyte count was determined in blood drawn from the tail vein, and DNA damage in leukocytes was assessed using the alkaline comet assay. Genotoxic effects of the test compounds were also evaluated in non-irradiated mice. The levels of radioprotection provided by both test compounds were c...
Source: Arhiv za Higijenu Rada i Toksikologiju - May 31, 2009 Category: Occupational Health Authors: Benković V, Knezević AH, Dikić D, Lisicić D, Orsolić N, Basić I, Kopjar N Tags: Arh Hig Rada Toksikol Source Type: journals

D-amphetamine toxicity in freshly isolated rat hepatocytes: a possible role of CYP3A.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The aim of this study was to trace D-amphetamine toxicity in isolated rat hepatocytes and to elucidate a possible involvement of CYP3A in the mechanisms of its toxicity. To this end, male Wistar rats were treated with nifedipine (5 mg kg(-1) i.p., 5 days), a substrate and inducer of CYP3A. Hepatocytes isolated from nifedipine-treated and control rats were incubated with D-amphetamine at a concentration of 100 micromol L(-1), which was determined to be an average toxic concentration (TC50) for the compound. To evaluate the possible toxic effects of D-amphetamine on freshly isolated rat hepatocytes, we assessed the follo...
Source: Arhiv za Higijenu Rada i Toksikologiju - May 31, 2009 Category: Occupational Health Authors: Vitcheva V, Kondeva-Burdina M, Mitcheva M Tags: Arh Hig Rada Toksikol Source Type: journals

Rat serum carboxylesterase partly hydrolyses gamma-butyrobetaine esters.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Although described some time ago, gamma-butyrobetaine esters and related compounds have not gained much attention from researchers, and their physiological function remains obscure. Formerly we detected GBB-esterase enzymatic activity in rat blood serum using phenylated gamma-butyrobetaine as an artificial substrate of the enzyme and HPLC. The aim of the present work was to develop an assay that would enable spectrophotometric or colorimetric determination of the reaction products of GBB-esterase activity and to reveal individual proteins performing GBB-esterase activity in rat blood serum. For this purpose gamma-butyr...
Source: Arhiv za Higijenu Rada i Toksikologiju - May 31, 2009 Category: Occupational Health Authors: Bagdoniene L, Labeikyte D, Kalviņs I, Borutinskaite V, Prokofjevs A, Trapencieris P, Juodka B, Sjakste N Tags: Arh Hig Rada Toksikol Source Type: journals

Comparative effects of calcium channel blockers, autonomic nervous system blockers, and free radical scavengers on diazinon-induced hyposecretion of insulin from isolated islets of Langerhans in rats.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study was designed to compare the effects of calcium channel blockers, alpha-adrenergic, beta-adrenergic, and muscarinic receptor blockers, and of free radical scavengers on insulin secretion from diazinon-treated islets of Langerhans isolated from the pancreas of rats using standard collagenase digestion, separation by centrifugation, and hand-picking technique. The islets were then cultured in an incubator at 37 degrees C and 5 % CO2. In each experimental set 1 mL of 8 mmol L(-1) glucose plus 125 microg mL(-1) or 625 microg mL(-1) of diazinon were added, except for the control group, which received 8 mmol L(-1) gluc...
Source: Arhiv za Higijenu Rada i Toksikologiju - May 31, 2009 Category: Occupational Health Authors: Pourkhalili N, Pournourmohammadi S, Rahimi F, Vosough-Ghanbari S, Baeeri M, Ostad SN, Abdollahi M Tags: Arh Hig Rada Toksikol Source Type: journals

Biological effects of Echinacea purpurea on human blood cells.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, biological effects observed after administration of Echinacea purpurea preparation suggest that it may be beneficial for the prevention of adverse health effects in workers exposed to ionising radiation. PMID: 19581209 [PubMed - in process] (Source: Arhiv za Higijenu Rada i Toksikologiju)
Source: Arhiv za Higijenu Rada i Toksikologiju - May 31, 2009 Category: Occupational Health Authors: Joksić G, Petrović S, Joksić I, Leskovac A Tags: Arh Hig Rada Toksikol Source Type: journals

Skin decontamination with mineral cationic carrier against sarin determined in vivo.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Our Institute's nuclear, biological, and chemical defense research team continuously investigates and develops preparations for skin decontamination against nerve agents. In this in vivo study, we evaluated skin decontamination efficacy against sarin by a synthetic preparation called Mineral Cationic Carrier (MCC) with known ion exchange, absorption efficacy and bioactive potential. Mice were treated with increasing doses of sarin applied on their skin, and MCC was administered immediately after contamination. The results showed that decontamination with MCC could achieve therapeutic efficacy corresponding to 3 x LD(50...
Source: Arhiv za Higijenu Rada i Toksikologiju - May 31, 2009 Category: Occupational Health Authors: Vucemilović A, Hadzija M, Jukić I Tags: Arh Hig Rada Toksikol Source Type: journals

In vitro genotoxicity of Settat town landfill leachate, Morocco.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
With the increasing use of landfill sites, leachates produced by uncontrolled waste disposal have became a serious threat for the aquatic environment. The aim of this study was to evaluate the genotoxicity of leachate and of well water sampled close to the town of Settat in Morocco using the micronucleus test and proliferation kinetics of human peripheral blood lymphocytes in vitro. We also analysed a number of physical and chemical parameters, including pH, % O2, chemical oxygen demand (COD), HCO3(-), Ca2+, Mg2+, Cl(-), and conductivity. The analysis showed much higher levels of nearly all parameters than the Moroccan...
Source: Arhiv za Higijenu Rada i Toksikologiju - May 31, 2009 Category: Occupational Health Authors: Amahdar L, Anouar A, Ababou B, Verschaeve L, Hilali A Tags: Arh Hig Rada Toksikol Source Type: journals

Antinuclear antibody and rheumatoid factor in silica-exposed workers.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A lot of workers in industries such as foundry, stonecutting, and sandblasting are exposed to higher than permissible levels of crystalline silica. Various alterations in humoral immune function have been reported in silicosis patients and workers exposed to silica dust. The aim of this study was to measure antinuclear antibody (ANA) and rheumatoid factor (RF) levels in foundry workers exposed to silica and to compare them with a control group without such exposure. ANA and RF were measured in 78 exposed and 73 non-exposed workers, and standard statistical methods were used to compare them. The two groups did not signi...
Source: Arhiv za Higijenu Rada i Toksikologiju - May 31, 2009 Category: Occupational Health Authors: Aminian O, Sharifian SA, Mehrdad R, Haghighi KS, Mazaheri M Tags: Arh Hig Rada Toksikol Source Type: journals

Interobserver variations in diagnosing asbestosis according to the ILO classification.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study has revealed a significant disagreement in the estimated degree of pleural and parenchymal asbestos pulmonary disease. This is why we believe high-resolution computed tomography (HRCT) should also be used as a part of international classification. PMID: 19581213 [PubMed - in process] (Source: Arhiv za Higijenu Rada i Toksikologiju)
Source: Arhiv za Higijenu Rada i Toksikologiju - May 31, 2009 Category: Occupational Health Authors: Perić I, Novak K, Barisić I, Mise K, Vucković M, Janković S, Tocilj J Tags: Arh Hig Rada Toksikol Source Type: journals

Prevalence of infection with Neisseria gonorrhoeae or Chlamydia trachomatis in acute mucopurulent cervicitis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The aim of this study was to determine the incidence of N. gonorrhoae (NG) and/or C. trachomatis (CT) in acute mucopurulent cervicitis (MPC). The study included 617 non-pregnant women with MPC, who had not been receiving any antimicrobial treatment. The average age of patients was 22.2 years. There were no statistically significant differences according to place of residence, education, and marital status. Samples for laboratory analysis were collected using a routine procedure; NG was identified using the cytochrome oxidase test and Gram staining. CT was isolated on McCoy cell culture and stained with Lugol solution. ...
Source: Arhiv za Higijenu Rada i Toksikologiju - May 31, 2009 Category: Occupational Health Authors: Ujević B, Habek JC, Habek D Tags: Arh Hig Rada Toksikol Source Type: journals

The eye--a neglected organ in environmental and occupational medicine: an overview of known environmental and occupational non-traumatic effects on the eyes.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article also discusses the influence of light exposure on retinal damage. It shows that very little information is available about the influence of environmental and occupational factors on the eye, and retina and retinal vessels in particular. PMID: 19581215 [PubMed - in process] (Source: Arhiv za Higijenu Rada i Toksikologiju)
Source: Arhiv za Higijenu Rada i Toksikologiju - May 31, 2009 Category: Occupational Health Authors: Rozanova E, Heilig P, Godnić-Cvar J Tags: Arh Hig Rada Toksikol Source Type: journals

Genetic polymorphism of metabolic enzymes P450 (CYP) as a susceptibility factor for drug response, toxicity, and cancer risk.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article brings a review of current knowledge on the relations between the polymorphisms of some CYPs and drug activity/toxicity and cancer risk. PMID: 19581216 [PubMed - in process] (Source: Arhiv za Higijenu Rada i Toksikologiju)
Source: Arhiv za Higijenu Rada i Toksikologiju - May 31, 2009 Category: Occupational Health Authors: Bozina N, Bradamante V, Lovrić M Tags: Arh Hig Rada Toksikol Source Type: journals

[Analysis of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in soil and sediment]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This review presents methods for the analysis of polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs), called dioxins, in soil and sediment. These compounds are produced as by-products of different combustion processes, and because of their persistency and toxicity they present a threat for animal and human health. Due to their high organic matter content, soil and sediment can accumulate dioxins and have become important secondary emission sources. Determining dioxins in these samples is complex because dioxins are present in trace levels and have to be separated from interferences where...
Source: Arhiv za Higijenu Rada i Toksikologiju - May 31, 2009 Category: Occupational Health Authors: Kozul D, Romanić SH Tags: Arh Hig Rada Toksikol Source Type: journals

Hypersensitivity to the pollen of olea europea in the mediterranean area.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19581218 [PubMed - in process] (Source: Arhiv za Higijenu Rada i Toksikologiju)
Source: Arhiv za Higijenu Rada i Toksikologiju - May 31, 2009 Category: Occupational Health Authors: Skitarelić N, Skitarelić N Tags: Arh Hig Rada Toksikol Source Type: journals

Andrija stampar and the institute for medical research and occupational health.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19329370 [PubMed - in process] (Source: Arhiv za Higijenu Rada i Toksikologiju)
Source: Arhiv za Higijenu Rada i Toksikologiju - March 1, 2009 Category: Occupational Health Authors: Sarić M Tags: Arh Hig Rada Toksikol Source Type: journals

Optimal methods of antigen retrieval for organic anion transporters in cryosections of the rat kidney.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To localise antigens by immunocytochemistry (IC), the samples of tissues or cells are usually denatured by fixation, and either frozen and cryosectioned, or embedded in paraffin before sectioning. p-Formaldehyde (PFA; formalin) is a common fixative, which preserves antigenicity of proteins, but damages the tissue/cell morphology and "masks" the antibody binding sites (epitopes). In order to "unmask" epitopes, some kind of antigen retrieval (AR) is used. The aim of this study was: a) to find an optimal AR method in cryosections of in vivo PFA-fixed kidneys for organic anion transporters (Oat) that reside in the basolate...
Source: Arhiv za Higijenu Rada i Toksikologiju - March 1, 2009 Category: Occupational Health Authors: Brzica H, Breljak D, Ljubojević M, Balen D, Micek V, Anzai N, Sabolić I Tags: Arh Hig Rada Toksikol Source Type: journals

Evaluation of oxime k203 as antidote in tabun poisoning.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We studied bispyridinium oxime K203 [(E)-1-(4-carbamoylpyridinium)-4-(4-hydroxyiminomethylpyridinium)-but-2-ene dibromide] with tabun-inhibited human acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) in vitro, and its antidotal effect on tabun-poisoned mice and rats in vivo. We compared it with oximes K048 and TMB-4, which have proven the most efficient oxime antidotes in tabun poisoning by now. Tabun-inhibited AChE was completely reactivated by K203, with the overall reactivation rate constant of 1806 L mol(-1) min(-1). This means that K203 is a very potent reactivator of tabun-inhibited AChE. In addition, ...
Source: Arhiv za Higijenu Rada i Toksikologiju - March 1, 2009 Category: Occupational Health Authors: Kovarik Z, Vrdoljak AL, Berend S, Katalinić M, Kuc K, Musilek K, Radić B Tags: Arh Hig Rada Toksikol Source Type: journals

Evaluation of the cytogenetic status of human lymphocytes after exposure to a high concentration of bee venom in vitro.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Several studies have reported radioprotective, antimutagenic, anti-inflammatory, antinociceptive, and anticancer effects of bee venom both in the cell and the whole organism. The aim of this study was to assess the effects of a single high dose of 100 microg mL(-1) of whole bee venom in human lymphocytes in vitro over a variety of time spans (from 10 min to 24 h). After the treatment, we used the comet assay and micronucleus test to see the effect of bee venom on the cell. The comet assay confirmed that the venom damaged the DNA molecule. Tail length, tail intensity, tail moment showed a significant increase (P < 0....
Source: Arhiv za Higijenu Rada i Toksikologiju - March 1, 2009 Category: Occupational Health Authors: Garaj-Vrhovac V, Gajski G Tags: Arh Hig Rada Toksikol Source Type: journals

Summer ozone concentrations in Zagreb area.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Ozone concentrations were measured at three sites in Zagreb (Croatia) in the summer of 2005. Two measuring sites were in urban areas, while the third site was in a rural area about 30 km to the south from the centre of Zagreb. Hourly ozone averages varied between 1 microg m(-3) and 209 microg m(-3). Average concentrations were the lowest in the rural area, even though elevated concentrations were recorded occasionally. However, the weather conditions during measurements were untypical for that time of the year; over the summer of 2005 there were many rainy and cloudy days. Ozone concentrations at all three sites were t...
Source: Arhiv za Higijenu Rada i Toksikologiju - March 1, 2009 Category: Occupational Health Authors: Pehnec G, Vadić V, Beslić I, Zuzul S Tags: Arh Hig Rada Toksikol Source Type: journals

Effect of organic and mineral soil fractions on sorption behaviour of chlorophenol and triazine micropollutants.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article compares the sorption behaviour of 2,4,6-trichlorophenol, 2,3,4,6-tetrachlorophenol, pentachlorophenol, chlorotriazine atrazine, methylthiotriazine ametryn, methoxytriazine atratone, hydroxyatrazine, and didelakylated atrazine in a topsoil and an aquifer sediment before and after removal of sorbent organic matter and in humic acid. Freundlich isotherm coefficients Kf and 1/n and free energy change (deltaG degrees ) were calculated for all compounds in all sorbents. According to sorbent pH values, chlorophenolate anions and uncharged triazine species dominated in all sorption experiments with topsoil and aquife...
Source: Arhiv za Higijenu Rada i Toksikologiju - March 1, 2009 Category: Occupational Health Authors: Stipicević S, Fingler S, Drevenkar V Tags: Arh Hig Rada Toksikol Source Type: journals

Total occupational exposure during characterisation, conditioning and securing of radioactive sealed sources: a new dosimetric concept using active electronic dosimeters.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article presents a dosimetric study assessing exposure to man-made ionising radiation of local environment and total occupational exposure of two professional workers involved in characterisation, conditioning, and securing of unused radioactive sealed sources. The purpose of the study was to validate a new active electronic dosimeter (AED) of type ALARA OD and to develop a new monitoring method by tracing the external occupational exposure over real time. This method is used to continuously measure and record external radiation doses and, which is a novelty, establish dose rates receiving pattern as a function of rea...
Source: Arhiv za Higijenu Rada i Toksikologiju - March 1, 2009 Category: Occupational Health Authors: Prlić I, Mihić MS, Marović G, Mestrović T Tags: Arh Hig Rada Toksikol Source Type: journals

An overview of the 1969-2007 follow-up study of chronic diseases and healthy ageing in croatia and pertinent publications.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article brings an overview of data collected in a follow-up study of chronic diseases in general adult population residing in inland and coastal Croatia, that was performed from 1969 to 2007. Despite the selection bias, the sample of volunteers examined in the last follow-up (2005 - 2007), now older than 70, remained as representative as in the previous three follow-ups (1969, 1972, and 1982). Here we report on the design of this prospective cohort study and on papers that have been published as a result. The obtained data could help in promoting healthy living and longevity. The results of our survey might also contr...
Source: Arhiv za Higijenu Rada i Toksikologiju - March 1, 2009 Category: Occupational Health Authors: Pavlović M, Corović N Tags: Arh Hig Rada Toksikol Source Type: journals

Prostate-specific antigen (PSA) in serum in relation to blood lead concentration and alcohol consumption in men.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The combined influence of age, smoking, alcohol, blood lead and cadmium concentrations, and serum copper, zinc, and selenium concentrations on prostate-specific antigen (PSA) in serum was investigated in a group of 57 men aged 21 years to 40 years. The subjects had no occupational exposure to metals and no other known reasons suspected of influencing prostate function or metal metabolism. No significant correlation was found between PSA and any of the explanatory variables considered. Nevertheless, when taking into account all of the above-mentioned potentially explanatory variables, the results of stepwise multiple re...
Source: Arhiv za Higijenu Rada i Toksikologiju - March 1, 2009 Category: Occupational Health Authors: Pizent A, Colak B, Kljaković Z, Telisman S Tags: Arh Hig Rada Toksikol Source Type: journals

Differences in peak bone density between male and female students.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
As an important determinant of osteoporotic fracture risk, peak bone density tends to be higher in men than in women. The aim of this study was to see whether young men and women differed in the time and skeletal region of peak bone density. We also investigated the influence of diet and physical activity on bone mass. The study group included 51 male and 75 female students aged 19 to 25 years. Bone mineral density was measured for the spine, total femur, and the distal third of the radius using dual energy x-ray absorptiometry. Dietary data were obtained using a specially designed semiquantitative food frequency quest...
Source: Arhiv za Higijenu Rada i Toksikologiju - March 1, 2009 Category: Occupational Health Authors: Avdagić SC, Barić IC, Keser I, Cecić I, Satalić Z, Bobić J, Gomzi M Tags: Arh Hig Rada Toksikol Source Type: journals

Exhaled breath condensate pH in adult Croatian population without respiratory disorders: how healthy a population should be to provide normative data?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The aim of this study was to obtain preliminary exhaled breath condensate (EBC) pH values for healthy adult Croatian subjects, and to evaluate criteria for defining respiratory health of population providing normal EBC pH values in epidemiologic studies. In 109 adults without a history of lower airway symptoms (AS), four groups were described by narrowing the definition of "health" down to 1) without lower AS; 2) without lower and upper AS; 3) without AS, with normal FEV(1) and bronchial normoreactivity; 4) without AS, with normal FEV(1), bronchial normoreactivity, normal total IgE, and with negative skin prick test. M...
Source: Arhiv za Higijenu Rada i Toksikologiju - March 1, 2009 Category: Occupational Health Authors: Varnai VM, Ljubicić A, Prester L, Macan J Tags: Arh Hig Rada Toksikol Source Type: journals

Is atopy related to neuroticism, stress, and subjective quality of life?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Different psychosocial characteristics have been associated with allergic disorders. The aim of this study was to examine whether atopic constitution and reports of allergic symptoms were related to personality trait of neuroticism, exposure to stressful life events and estimates of quality of life. Atopy was determined by skin prick test and reports of nasal and pulmonary allergy-related symptoms. Actively working individuals of both genders took part in the study (n=145, age range: 20 to 66 years). The participants were divided in three groups. The first group was composed of those with negative skin prick test and w...
Source: Arhiv za Higijenu Rada i Toksikologiju - March 1, 2009 Category: Occupational Health Authors: Radosević-Vidacek B, Kosćec A, Bakotić M, Macan J, Bobić J Tags: Arh Hig Rada Toksikol Source Type: journals

Disturbance of cell proliferation in response to mobile phone frequency radiation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The aim of study was to determine the influence of mobile phone frequency radiation on the proliferation, cytoskeleton structure, and mitotic index of V79 cells after 1 h, 2 h, and 3 h of exposure. V79 cells were cultured in standard laboratory conditions and exposed to continuous-wave (CW) RF/MW radiation of 935 MHz, electric field strength of (8.2+/-0.3) V m(-1), and specific absorption rate (SAR) of 0.12 W kg(-1). To identify proliferation kinetics, the cells were counted for each hour of exposure 24 h, 48 h, 72 h, and 96 h after respective exposures. Microtubule proteins were determined using specific immunocytoche...
Source: Arhiv za Higijenu Rada i Toksikologiju - March 1, 2009 Category: Occupational Health Authors: Trosić I, Pavicić I Tags: Arh Hig Rada Toksikol Source Type: journals

Frontotemporal dementias: update on recent developments in molecular genetics and neuropathology.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Frontotemporal dementias (FTD) are the second most common type of presenile dementias, considered to be clinically and pathologically different from Alzheimer's dementia (AD). FTD differs clinically from AD because memory loss is rarely an early symptom. Instead, FTD is usually denoted by behavioural and language difficulties, and may co-occur with motor neuron disease (MND). Frontotemporal lobar degeneration (FTLD) with ubiquitin-positive, tau-negative inclusions (FTLD-U) is the most common underlying pathology with and without MND. TAR DNA-binding protein 43 (TDP-43), encoded by the TARDBP gene, has been identified a...
Source: Arhiv za Higijenu Rada i Toksikologiju - March 1, 2009 Category: Occupational Health Authors: Liscić RM Tags: Arh Hig Rada Toksikol Source Type: journals

Estimation of stability constants of coordination compounds using models based on topological indices.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The principal aim of our research was to develop theoretical models for estimating stability constants of coordination compounds, focusing on chelates of heavy metals, Cu(II) and Ni(II), with bioligands (amines, amino acids and peptides). We tried to solve the problem using graph-theoretical models. We also encountered a specific problem for coordination compounds--the choice of the constitutional formula, that is graph, of the complex species. PMID: 19329384 [PubMed - in process] (Source: Arhiv za Higijenu Rada i Toksikologiju)
Source: Arhiv za Higijenu Rada i Toksikologiju - March 1, 2009 Category: Occupational Health Authors: Raos N, Milicević A Tags: Arh Hig Rada Toksikol Source Type: journals

[Cytotoxicity of polyphenolic/flavonoid compounds in a leukaemia cell culture]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Flavonoid components of propolis are biologically active substances with antioxidative, immunostimulative, immunomodulative, and anti-inflamatory properties. The aim of the study was to investigate their cytotoxic effect on different leukaemia cell lines. For this purpose we used five different flavonoids (quercetin, caffeic acid, chrysin, naringenin, and naringin) and five types of leukemia cell lines (MOLT, JURKAT, HL-60, RAJI and U937). Cells were cultured at 37 degrees C in the RPMI-1640 medium supplemented with 10% FCS in humified atmosphere with 5% of CO2. Flavonoids were added in the following concentrations: 10...
Source: Arhiv za Higijenu Rada i Toksikologiju - December 1, 2008 Category: Occupational Health Authors: Josipović P, Orsolić N Tags: Arh Hig Rada Toksikol Source Type: journals

[Carbon in particulate matter in the air]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Carbon in Particulate Matter in the AirCarbon (Latin carbo) in elemental form appears as diamond, graphite, fullerene, and black amorphous carbon. Black amorphous carbon can be found in atmospheric aerosols and its main forms are elemental (EC), organic (OC), and carbonate (CC) carbon. Atmospheric carbon particles are transmitted through more than 70 sources of air pollutants. Elemental carbon is the primary pollutant, which results from incomplete combustion of fossil and biomass fuels. It also appears as soot, in sediment, soil, and ice core. Many quantitative determinations of elemental carbon are based on its chemi...
Source: Arhiv za Higijenu Rada i Toksikologiju - December 1, 2008 Category: Occupational Health Authors: Godec R Tags: Arh Hig Rada Toksikol Source Type: journals

Asbestosis and Catalase Genetic Polymorphism.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study investigates whether CAT -262 C>T genetic polymorphism influences the risk of asbestosis in workers occupationally exposed to asbestos.The nested case-control study included 262 cases with asbestosis and 265 controls with no asbestos-related disease. Data on cumulative asbestos exposure and smoking were available. A real-time PCR assay was introduced for genotyping CAT -262 C>T promoter polymorphism.A slightly elevated risk of asbestosis was observed in subjects with the CAT -262 TT genotype compared to others (OR=1.36, CI 0.70-2.62). This risk did not change substantially after adjustment by sex, age, and...
Source: Arhiv za Higijenu Rada i Toksikologiju - December 1, 2008 Category: Occupational Health Authors: Franko A, Dolžan V, Arnerić N, Dodič-Fikfak M Tags: Arh Hig Rada Toksikol Source Type: journals

The Association of OGG1 Ser326Cys Polymorphism and Urinary 8-OHdG Levels With Lung Cancer Susceptibility: A Hospital-Based Case-Control Study in Turkey.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
High incidence and poor prognosis of lung cancer make it a major health problem worldwide. Although smoking is a major cause of lung cancer, only some smokers develop lung cancer, which suggests that there is a genetic predisposition in some individuals. 8-OHG is an important oxidative base lesion and may elevate due to cancer and smoking. It is repaired by 8-hydroxyguanine DNA glycosylase 1 (OGG1), which has several polymorphisms. Although the Ser326Cys polymorphism is consistently associated with a range of cancers, findings about this polymorphism and lung cancer risk are contradictory. To date, no study has examine...
Source: Arhiv za Higijenu Rada i Toksikologiju - December 1, 2008 Category: Occupational Health Authors: Karahalil B, Emerce E, Koçer B, Han S, Alkiş N, Karakaya AE Tags: Arh Hig Rada Toksikol Source Type: journals

Chromosome Aberrations in Peripheral Blood Lymphocytes of Croatian Hospital Staff Occupationally Exposed to Low Levels of Ionising Radiation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study investigated the cytogenetic effects of low-level ionising x-radiation in 48-hour peripheral blood lymphocyte cultures sampled from 765 hospital staff occupationally exposed to several agents known or suspected to induce chromosome damage and compared them with 200 control subjects. The exposed subjects were divided in eight (8) groups according to their specialities and job titles. The exposed groups manifested an increase in all types of chromosome aberrations. Acentric fragments were the most frequent chromosome-type aberration. Dicentric chromosomes were statistically significant only in urologists/gynaecolo...
Source: Arhiv za Higijenu Rada i Toksikologiju - December 1, 2008 Category: Occupational Health Authors: Kašuba V, Rozgaj R, Jazbec A Tags: Arh Hig Rada Toksikol Source Type: journals

Distribution of Lindane in Water, Sediment, and Fish from the Warri River of the Niger Delta, Nigeria.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This paper is the first attempt to quantify the levels and the distribution pattern of lindane in the surface water, sediment and fish (Chrysichthys furcatus and Tilapia zilli). The samples were collected from three stations (Ovwian, Ekakpamre, and Ovu) of the Warri River in the western Niger Delta of Nigeria in 2006: during the dry (January-April) and wet seasons (May-August). The analysis included a total of 96 samples made up of 24 samples each for water, sediment, and fish. The pesticide levels were analysed using high performance liquid chromatography to elucidate its distribution in various environmental compartm...
Source: Arhiv za Higijenu Rada i Toksikologiju - December 1, 2008 Category: Occupational Health Authors: Ezemonye LI, Ikpesu TO, Tongo I Tags: Arh Hig Rada Toksikol Source Type: journals

Arsenic Exposure through Drinking Water and its Effect on Pregnancy Outcome in Bengali Women.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Twelve districts of the state of West Bengal, India are affected by arsenic (As) and millions of individuals are consuming As-contaminated groundwater. The probable adverse effects of As on pregnancy outcome (stillbirth and miscarriage) are yet to be properly studied. The present investigation is an attempt to understand the effects of As exposure on the pregnancy outcome in Bengali women exposed to As through drinking water and residing in different villages in North 24 Parganas District of West Bengal. The results show a significantly higher rate of stillbirths and miscarriages than those in the unexposed population....
Source: Arhiv za Higijenu Rada i Toksikologiju - December 1, 2008 Category: Occupational Health Authors: Sen J, Chaudhuri AB Tags: Arh Hig Rada Toksikol Source Type: journals