Arteriosclerosis, Thrombosis and Vascular Biology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Spatial Atlas for Mapping Vascular Microcalcification Using 18F-NaF PET/CT: Application in Hyperphosphatemic Familial Tumoral Calcinosis
CONCLUSIONS: This technique affords the ability to visualize spatial patterns of the active microcalcification process in the peripheral vasculature. Further, this technique affords the ability to track microcalcifications at precise locations not only across time but also across subjects. This technique is readily adaptable to other diseases of vascular calcification and may represent a significant advance in the field of vascular biology.PMID:38660800 | DOI:10.1161/ATVBAHA.123.320455 (Source: Arteriosclerosis, Thrombosis and Vascular Biology)
Source: Arteriosclerosis, Thrombosis and Vascular Biology - April 25, 2024 Category: Cardiology Authors: Aaron J Sheppard Elizabeth H Theng Sriram S Paravastu Natalia M Wojnowski Faraz Farhadi Michael A Morris Iris R Hartley Rachel I Gafni Kelly L Roszko Michael T Collins Babak Saboury Source Type: research

Mild Hypoxia Accelerates Cerebral Cavernous Malformation Disease Through CX3CR1-CX3CL1 Signaling
CONCLUSIONS: Our study reveals that interactions between CX3CR1 and CX3CL1 can modify CCM neuropathology when lesions are accelerated by environmental hypoxia. Moreover, a hypoxic environment or hypoxia signaling caused by CCM disease influences the balance between neuroinflammation and neuroprotection mediated by CX3CR1-CX3CL1 signaling. These results establish CX3CR1 as a genetic marker for patient stratification and a potential predictor of CCM aggressiveness.PMID:38660801 | DOI:10.1161/ATVBAHA.123.320367 (Source: Arteriosclerosis, Thrombosis and Vascular Biology)
Source: Arteriosclerosis, Thrombosis and Vascular Biology - April 25, 2024 Category: Cardiology Authors: Eduardo Frias-Anaya Helios Gallego-Gutierrez Brendan Gongol Shantel Weinsheimer Catherine Chinhchu Lai Marco Orecchioni Aditya Sriram Cassandra M Bui Bliss Nelsen Preston Hale Angela Pham Robert Shenkar Dorothy DeBiasse Rhonda Lightle Romuald Girard Ying Source Type: research

Wnt Signaling Inhibition Prevents Postnatal Inflammation and Disease Progression in Mouse Congenital Myxomatous Valve Disease
CONCLUSIONS: Wnt signaling is involved in the initiation of mitral valve abnormalities and inflammation but is not responsible for later-stage valve disease progression once it has been initiated. Thus, Wnt signaling contributes to MVD progression in a time-dependent manner and provides a promising therapeutic target for the early treatment of congenital MVD in Marfan syndrome.PMID:38660802 | DOI:10.1161/ATVBAHA.123.320388 (Source: Arteriosclerosis, Thrombosis and Vascular Biology)
Source: Arteriosclerosis, Thrombosis and Vascular Biology - April 25, 2024 Category: Cardiology Authors: Na Xu Christina M Alfieri Yang Yu Minzhe Guo Katherine E Yutzey Source Type: research

Effects of a Global < em > Rab27a < /em > Null Mutation on Murine PVAT and Cardiovascular Function
CONCLUSIONS: Global RAB27A loss impacted perivascular adipose tissue and thoracic aorta proteomic signatures, altered vasocontractile responses, and decreased left ventricular ejection fraction in mice.PMID:38660803 | DOI:10.1161/ATVBAHA.124.320969 (Source: Arteriosclerosis, Thrombosis and Vascular Biology)
Source: Arteriosclerosis, Thrombosis and Vascular Biology - April 25, 2024 Category: Cardiology Authors: Ashley Soucy Christian Potts Abigail Kaija Anne Harrington Marissa McGilvrey George L Sutphin Ron Korstanje Benjamin Tero Jacob Seeker Ilka Pinz Calvin Vary Larisa Ryzhova Lucy Liaw Source Type: research

Differential Impact In Vivo of Pf4- ΔCre-Mediated and Gp1ba-ΔCre-Mediated Depletion of Cyclooxygenase-1 in Platelets in Mice
CONCLUSIONS: Both approaches to Cox-1 deletion similarly restrain thrombogenesis, but a differential impact on Cox-1-dependent prostanoid formation by the vasculature may contribute to an inflammatory phenotype and accelerated atherogenesis in Pf4-ΔCre mice.PMID:38660804 | DOI:10.1161/ATVBAHA.123.320295 (Source: Arteriosclerosis, Thrombosis and Vascular Biology)
Source: Arteriosclerosis, Thrombosis and Vascular Biology - April 25, 2024 Category: Cardiology Authors: Soon Yew Tang Ronan Lordan Hu Meng Benjamin J Auerbach Elizabeth J Hennessy Arjun Sengupta Ujjalkumar S Das Robin Joshi Oscar A Marcos-Contreras Ryan McConnell Gregory R Grant Emanuela Ricciotti Vladimir R Muzykantov Tilo Grosser Aalim M Weiljie Garret A Source Type: research

Potential Influence of Risk Factor Control on the Association Between Lipoprotein(a) and Atherosclerotic Cardiovascular Disease
Arterioscler Thromb Vasc Biol. 2024 Apr 25. doi: 10.1161/ATVBAHA.124.320990. Online ahead of print.NO ABSTRACTPMID:38660805 | DOI:10.1161/ATVBAHA.124.320990 (Source: Arteriosclerosis, Thrombosis and Vascular Biology)
Source: Arteriosclerosis, Thrombosis and Vascular Biology - April 25, 2024 Category: Cardiology Authors: Jonas Ghouse Gustav Ahlberg S øren Albertsen Rand Morten Salling Olesen Bjarni Vilhjalmsson Stefan Stender Henning Bundgaard Source Type: research

Immunoproteasomal Inhibition With ONX-0914 Attenuates Atherosclerosis and Reduces White Adipose Tissue Mass and Metabolic Syndrome in Mice
CONCLUSIONS: We propose that immunoproteasomal inhibition reduces 3 major causes underlying cardiovascular disease, dyslipidemia, metabolic syndrome, and inflammation and is a new target in drug development for atherosclerosis treatment.PMID:38660806 | DOI:10.1161/ATVBAHA.123.319701 (Source: Arteriosclerosis, Thrombosis and Vascular Biology)
Source: Arteriosclerosis, Thrombosis and Vascular Biology - April 25, 2024 Category: Cardiology Authors: Frank H Schaftenaar Andrea D van Dam Gerjan de Bruin Marie A C Depuydt Jill de Mol Jacob Amersfoort Hidde Douna Menno Meijer Mara J Kr öner Peter J van Santbrink Mireia N A Bernab é Kleijn Gijs H M van Puijvelde Bogdan I Florea Bram Sl ütter Amanda C F Source Type: research

Interactions Between HDL and CD4+ T Cells: A Novel Understanding of HDL Anti-Inflammatory Properties
We present a model where HDL may modulate T cells through both direct and indirect mechanisms.PMID:38660807 | DOI:10.1161/ATVBAHA.124.320851 (Source: Arteriosclerosis, Thrombosis and Vascular Biology)
Source: Arteriosclerosis, Thrombosis and Vascular Biology - April 25, 2024 Category: Cardiology Authors: Laura Atehortua W Sean Davidson Claire A Chougnet Source Type: research

Global Health Burden of Venous Thromboembolism
Arterioscler Thromb Vasc Biol. 2024 May;44(5):1007-1011. doi: 10.1161/ATVBAHA.124.320151. Epub 2024 Apr 24.NO ABSTRACTPMID:38657032 | DOI:10.1161/ATVBAHA.124.320151 (Source: Arteriosclerosis, Thrombosis and Vascular Biology)
Source: Arteriosclerosis, Thrombosis and Vascular Biology - April 24, 2024 Category: Cardiology Authors: Aaron Wendelboe Jeffrey I Weitz Source Type: research

Vaping Versus Smoking: Are Electronic-Cigarettes the Savior?
Arterioscler Thromb Vasc Biol. 2024 May;44(5):1012-1015. doi: 10.1161/ATVBAHA.123.319575. Epub 2024 Apr 24.NO ABSTRACTPMID:38657033 | DOI:10.1161/ATVBAHA.123.319575 (Source: Arteriosclerosis, Thrombosis and Vascular Biology)
Source: Arteriosclerosis, Thrombosis and Vascular Biology - April 24, 2024 Category: Cardiology Authors: David Bernhard Barbara Messner Source Type: research

Cardiac Lymphangiogenesis in CVDs
Arterioscler Thromb Vasc Biol. 2024 May;44(5):1016-1020. doi: 10.1161/ATVBAHA.123.319572. Epub 2024 Apr 24.NO ABSTRACTPMID:38657034 | DOI:10.1161/ATVBAHA.123.319572 (Source: Arteriosclerosis, Thrombosis and Vascular Biology)
Source: Arteriosclerosis, Thrombosis and Vascular Biology - April 24, 2024 Category: Cardiology Authors: Ebba Brakenhielm Ibrahim Sultan Kari Alitalo Source Type: research

Century of Milestones and Breakthroughs Related to the Immune Mechanisms of Atherosclerosis
Arterioscler Thromb Vasc Biol. 2024 May;44(5):1002-1006. doi: 10.1161/ATVBAHA.124.319397. Epub 2024 Apr 24.NO ABSTRACTPMID:38657035 | DOI:10.1161/ATVBAHA.124.319397 (Source: Arteriosclerosis, Thrombosis and Vascular Biology)
Source: Arteriosclerosis, Thrombosis and Vascular Biology - April 24, 2024 Category: Cardiology Authors: Ziad Mallat Alain Tedgui Source Type: research

Correction to: Dysfunctional APPL1-Mediated Epigenetic Regulation in Diabetic Vascular Injury
Arterioscler Thromb Vasc Biol. 2024 May;44(5):e171. doi: 10.1161/ATV.0000000000000171. Epub 2024 Apr 24.NO ABSTRACTPMID:38657036 | DOI:10.1161/ATV.0000000000000171 (Source: Arteriosclerosis, Thrombosis and Vascular Biology)
Source: Arteriosclerosis, Thrombosis and Vascular Biology - April 24, 2024 Category: Cardiology Source Type: research

Role of the Lymphatics in Cardiac Disease
Arterioscler Thromb Vasc Biol. 2024 Apr 18. doi: 10.1161/ATVBAHA.124.319854. Online ahead of print.ABSTRACTCardiovascular diseases remain the largest cause of death worldwide with recent evidence increasingly attributing the development and progression of these diseases to an exacerbated inflammatory response. As a result, significant research is now focused on modifying the immune environment to prevent the disease progression. This in turn has highlighted the lymphatic system in the pathophysiology of cardiovascular diseases owing, in part, to its established function in immune cell surveillance and trafficking. In this ...
Source: Arteriosclerosis, Thrombosis and Vascular Biology - April 18, 2024 Category: Cardiology Authors: Susanna T E Cooper Adam B Lokman Paul R Riley Source Type: research

Atherosclerotic Plaque Epigenetic Age Acceleration Predicts a Poor Prognosis and Is Associated With Endothelial-to-Mesenchymal Transition in Humans
CONCLUSIONS: Plaque EAA is a strong and independent marker of poor outcome in patients with severe atherosclerosis. Plaque EAA was linked to mesenchymal endothelial and smooth muscle cells. Endothelial-to-mesenchymal transition was associated with EAA, which was experimentally validated. Epigenetic aging mechanisms may provide new targets for treatments that reduce atherosclerosis complications.PMID:38634280 | DOI:10.1161/ATVBAHA.123.320692 (Source: Arteriosclerosis, Thrombosis and Vascular Biology)
Source: Arteriosclerosis, Thrombosis and Vascular Biology - April 18, 2024 Category: Cardiology Authors: Ernest Diez Benavente Robin J G Hartman Tim R Sakkers Marian Wesseling Yannicke Sloots Lotte Slenders Arjan Boltjes Barend M Mol Gert J de Borst Dominique P V de Kleijn Koen H M Prange Menno P J de Winther Johan Kuiper Mete Civelek Sander W van der Laan S Source Type: research