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Conjunctivitis – allergy or dry eye syndrome?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article is a guide proposition first of all for general practitioners, but also for other specialists. It consists of two steps: the questions which should be asked to the patient, and basic examination of the eye. In this way most mild allergic conjunctivitis can be diagnosed and treated successfully. The differential diagnosis of “red eye” and the urgent causes of this sign are also presented in this article. (Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house)
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Contact eczemaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
is one of the most common clinical pictures seen in general practice. This is not a defined disease, but rather an umbrella term for a group of diseases with various aetiology that share common features in the clinical picture and course of the disease. The term itself implies that the causative factor provokes disease through direct contact with the skin. The following diseases fit into the spectrum of contact eczema: 1) Allergic contact eczema (allergic contact dermatitis), in which a low-molecular weight chemical compound (hapten) penetrates into the skin, and binds to an autologous protein to form an antigen that can ...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Reccurent infections and asthma and allergic diseases in childrenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The relationships between recurrent infections, asthma and allergic diseases have been analyzed for many years. Suggestions for practice seem important and expected. Quite often it is not easy to differentiate an allergic reaction and infection, especially in the case of viral infection with mild symptoms. Sometimes both pathologies are completely independent. The main discussion focuses on the role of infection in the development of diseases and its role as a triggering factor of asthma exacerbation. For many years the concept of promotion of asthma and allergy in the course of viral infection has dominated and has been s...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Application of antihistamines in ear, nose and throat disordersEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study was a review of the antihistamines (AH) in allergic rhinitis (AR). Most patients had comorbid ocular symptoms, asthma and anxiety. Fifty-five percent consulting for the first time were diagnosed with AR, of whom 2/3 also had conjunctivitis and 1/3 asthma. In other study 3/4 asthma patients had AR and 1/4 did not. Every five required in the preceding year a treatment in emergency departments. The routine use of antihistamines for treating otitis exudativa in children cannot be recommended. Antihistamines were the most commonly prescribed or recommended symptomatic medicines in sinusitis (1/4 of the patients). Abo...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

The food allergy in medical practiceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The food protein triggering the allergic response is termed a food allergen. Six to eight percent of children under the age of three have food allergies and nearly four percent of adults have them. The most common food allergies in adults are shellfish, peanuts, tree nuts, fish, and eggsand the most common food allergies in children are milk, eggs, peanuts, and tree nus. Conditions caused by food allergies are classified into 3 groups according to the mechanism of the allergic response. The reaction may progress to anaphylactic shock: a systemic reaction involving several different bodily systems including hypotension (low...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Sesje plakatoweEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house)
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Non-allergic rhinitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(NAR) can be defined as a chronic nasal inflammation which is not caused by systemic IgE-dependent mechanisms. Non-allergic rhinitis is common and probably affects far more than 200 million people worldwide, both children and adults. Asthma was more frequently associated with NAR than with AR. Non-allergic rhinitis was more frequently associated with older age, perennial symptoms and female gender. More NAR than AR patients also had drug allergy, pharyngitis, sinusitis (CRS) and urticaria. Chronic rhinosinusitis was not significantly different in allergic and non-allergic patients. Nasal polyps were found equally in both ...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Asthma in children older than 5 yearsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
High-risk birth cohorts continue to point to atopy as the main risk factor for developing asthma. However, rising trends in non-IgE-dependent asthma, such as viral-induced and exercise-induce asthma, are visible. There is a strong temporal association between viral respiratory infections and acute obstructive/asthmatic episodes. Nevertheless, the role of viral infections in the pathogenesis of asthma remains poorly characterized. The factors that could explain this association are heterogeneous and sometimes contradictory. While exercise-induced asthma seems to be less controversial, such symptoms attract attention and sho...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

The significance of allergology in family medicineEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A family doctor plays a crucial role in prevention, early diagnosis and treatment of allergic diseases, in children as well as in adults. In the population of patients under control of a family doctor are many people suffering from allergic diseases and the doctor has an influence on diagnosis, treatment and control of the progress of a disease. In the case of symptoms appearing or worsening, a patient goes to his family doctor to seek advice and release from suffering. It is essential to set plain algorithms of proceedings in individual allergic diseases, which are addressed especially at family doctors, because not all o...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Difficult asthma in childrenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The assessment of patients with difficult asthma comprises three major issues: 1) does the patient really have asthma, 2) is the patient compliant with prescribed therapy, and 3) are there any environmental or co-morbid factors worsening asthma? (Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house)
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Anaphylaxis in childrenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Anaphylaxis, though rare, is an increasing emergency especially in children and remains under-diagnosed and undertreated. Boys outnumber girls by 3 : 2 in preschool children, but from the age of 15 females predominate. Food is the main trigger of anaphylaxis in children with the commonest being nuts and milk. The diagnosis is primarily based on the clinical history and clinical criteria. The most to less frequent symptoms concern dermatological, respiratory, gastrointestinal and cardiovascular ones, respectively. Emergency management requires the life support ABCDE approach. Intramuscular adrenalin, repeated as required, i...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

The importance of small airways inflammation control in the course and therapy of bronchial asthmaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Changes in the structure and function of the small airways (< 2 mm diameter) play a major role in airflow limitation in bronchial asthma. Features of cellular inflammation, consisting of an infiltrate rich in lymphocytes and eosinophils, are present in the small airways of patients with asthma. It is suggested that inflammation in the small airways may be responsible for severe asthma and symptoms of nocturnal asthma. It was documented that applied inhaled therapy did not give sufficient control of inflammation in the small airways, because anti-inflammatory medicines were able to penetrate only into the middle bronchi. Fo...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

What’s new in the treatment of atopic dermatitis?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Atopic dermatitis (AD, atopic eczema) is one of the most common inflammatory skin diseases, with a chronic or relapsing course and strong itching. The prevalence of AD has increased over the last years tremendously. Atopic dermatitis impacts negatively the quality of life of both patients and their families. Largely on the basis of the recently described association of atopic dermatitis and the genetically inherited abnormalities in filaggrin expression, atopic dermatitis is considered at least partially a primary disorder of stratum corneum structure and function. Treatments improving this function may reduce the likeliho...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

PhotoallergiesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Photoallergic diseases – solar urticaria and photoallergic contact dermatitis – are encountered in every allergist’s practice. Unfortunately, most such cases are treated non-specifically as “sun allergy” and remain undiagnosed. Focused diagnostic procedures – photoprovocation and photopatch testing – would enable the managing physician to find the actual cause and select the most adequate treatment. Solar urticaria (SU) is an IgE-dependent photoallergic disease. The suspicion of SU should always be taken into account when the following features are observed: 1) development of pruri...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

What’s new in contact allergy?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Allergic contact dermatitis is a frequent, chronic skin disease, mainly of occupational origin. It affects younger and younger individuals, involves some economic costs and causes a decrease in quality of life. In the nineteen seventies and eighties the distribution of contact allergy in Poland was significantly different in comparison with Western Europe. The most frequent allergens were chromates, aromatic amines, turpentine and epoxy resins, while the frequency of sensitization to nickel, acrylic plastics and neomycin was lower than in other European countries. At present, there are only slight differences in occurrence...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Skin barrier dysfunction as a risk factor for development of allergic disordersEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The outermost layer of the skin, the stratum corneum, primarily mediates permeability barrier function. The formation of corneocytes is considered to be the result of a finely regulated differentiation process. During the terminal differentiation process structural change of the keratinocyte is associated with the sequential formation of differentiation marker proteins keratin 5 and 14 present in the stratum basale, keratin 1 and 10 in the stratum spinosum, and late differentiation marker proteins filaggrin, loricrin and involucrin in the granular layer. The granular layer is composed of secretory cells producing polar lip...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Selected problems of immunotherapy in childrenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
As one of the causal treatment methods in patients with allergic diseases immunotherapy has almost a 100-year history. In spite of such a long period of practice, observation and research in this field, not all relevant problems have been solved. This concerns mainly immunotherapy in treatment of children. Indications for immunotherapy during development age are the same as in maturity. While qualifying for this form of treatment a possibility of allergic disease natural evolution in this age should always be taken into consideration, as well as the greater part of atopy in pathogenesis of asthma in children. Therefore the...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Immunotherapy in adults and seniors – clinical aspectsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Specific allergen immunotherapy (SIT) is a broadly used and highly effective therapeutic method of treating respiratory allergies and insect venom allergy (venom immunotherapy – VIT). Specific allergen immunotherapy is generally recommended for adults > 60, but the age criterion does not apply to VIT since venom allergy is a life-threatening condition. The frequency of the occurrence of anaphylactic events during SIT is comparable in both groups of younger and older patients, but if the events do occur, they tend to be more severe in the latter group. The higher risk of a severe anaphylactic reaction occurring in old...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Should all children with asthma be treated with antileukotrienes – a review of clinical trialsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In the treatment of persistent asthma, randomized controlled trials have shown leukotriene inhibitors to be more effective than placebo but less effective than inhaled corticosteroids. The use of leukotriene inhibitors has shown an inhaled-steroid-sparing effect, a reduction in need for systemic steroid treatment, or cost savings. In the light of the results of our study montelukast seems to be the best therapeutic option for exercise-induced asthma. Interestingly, montelukast may have some preventive activity against viral-induced asthma exacerbations. There is strong evidence for clinical effectiveness of montelukast in ...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

The molecular traits of food allergensEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Allergens are defined as environmental agents that induce IgE-mediated immediate hypersensitivity reactions following inhalation, ingestion or injection. Purified allergens are named using the systematic nomenclature of the Allergen Nomenclature Sub-Committee of the World Health Organization and International Union of Immunological Societies. Major allergens may have special aerobiological properties and allergenic structures. Allergens are derived from proteins with a variety of biological functions, including proteases, ligand-binding proteins, structural proteins, pathogenesis-related proteins, lipid transfer proteins, ...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Allergic rhinitis and lower airwaysEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A close relation between allergic rhinitis (AR) and asthma has been reported by many epidemiological and clinical studies. However, the nature of this relation remains unclear. Asthma and AR most frequently coexist in children and adults. AR is a strong risk factor for non-specific bronchial hyperreactivity and is also an independent risk factor for development of asthma. Uncontrolled AR worsens the clinical course of asthma. (Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house)
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Food-related asthma – proEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Some foods are capable of provoking asthmatic symptoms. In over 8% of children, the aetiology of asthma was food-related. Children admitted to intensive care were significantly more likely to report food allergy (FA) – 7 times more at least one FA compared with children seen in the ambulatory setting. The association was stronger among children with multiple or severe FA. Children with FA developed asthma earlier and at higher prevalence. Asthma mortality in children and young adults: FA and inadequate treatment were the major risk factors. An alarming finding was that 11 of the 37 deaths were probably caused by FA. ...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Can asthma control be achieved?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
International guidelines for asthma management and prevention – GINA 2006 (Global Strategy for Asthma) currently recommend low-dose ICS as a first line therapy for patients with mild persistent asthma (the second step of therapy), and medium-dose of ICS or combination therapy with LABAs as the preferred therapy for moderate asthma (the third step of therapy). Achieving asthma control is a main therapeutic goal. Although combination of ICS and LABA is generally effective pharmacotherapy, many patients fail to achieve partial or full control with available therapies. Experiments have led to the development of a fixed c...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Cardiovascular safety in treatment of bronchial asthmaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nowadays interdisciplinary problems become more and more important in medicine. Most, if not all the patients in real world are treated not on one isolated disease but two or more serious concomitant diseases. Therefore, it happens more and more often that medications used in treatment of one disease have adverse effects or are even harmful in the treatment of another disease. In the patients with cardiovascular and respiratory diseases medications acting on beta receptors are problematic. It is known that b-blockers, one of the main group of cardiac drugs, have beneficial effects on the heart but might cause bronchospasm ...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Allergen immunotherapy in polysensitized patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Allergen immunotherapy (AIT) is effective in treatment of allergic diseases including allergic rhinoconjunctivitis and allergic asthma. The majority of allergic patients are sensitized to at least two non-related allergens. Only a few controlled clinical studies report results concerning efficacy of AIT in polysensitized patients. Allergen immunotherapy with a single allergen in polysensitized patients is effective during AIT. In patients sensitized to two non-related allergens AIT with two non-related allergens seems to be more effective than AIT with any allergen alone. Before starting AIT it is very important to establi...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Original paper Urban-rural differences in the prevalence of atopic diseases in the general population in Lodz Province (Poland)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The study revealed a difference in the prevalence of atopic diseases between city and rural areas. The high prevalence of atopic dermatitis in the rural area may be a portent of an increase in other atopic diseases and the disappearance of the differences between city and rural areas. (Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house)
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Spirometry in healthy and diseased. How it looks and how it should look like?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Spirometry is most widely used pulmonary function test. Good quality of a test is essential for reliable assessment of lung function and interpretation of the results. Spirometry is usually performed in seated position, because of safety reasons. Age, height and weight, sex, and race must be recorded for calculating reference values. The forced exhalation maneuver to measure FVC and FEV1 has three phases: full inhalation, initial blast, and smooth completion of exhalation. Application of a nose clip is recommended. The ATS/ERS set specific criteria that must be met in order for the test to be considered valid. To be accept...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Local allergic reaction in the conjunctiva – therapeutic implicationsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The eye is exposed to many foreign substances, and ocular tissues have a complete array of immune cells to initiate an immunological response. The external eye represents an ideal site for allergic reactions because of the high number of mast cells and potential local synthesis of IgE. Mild allergic diseases such as IAC and PAC are classical example of type I hypersensitivity. The central mechanism in the pathogenesis of these diseases is IgE-mediated reactions and then T lymphocytes, eosinophils and conjunctival structural cells activation. But the severest forms of ocular allergy are more complicated and involve a cellul...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Dry eye in an allergic patient – how to avoid, how to treat?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Allergic conjunctivitis and dry eye are major ocular surface disorders affecting millions of people. Although neither of them is a sight-threatening disease, they have a serious impact on patients’ quality of life. A typical clinical symptom of allergic conjunctivitis is itching, whereas the symptoms of dry eye are burning sensation, irritation or ocular fatigue, but allergic conjunctivitis and dry eye sometimes share very similar symptoms. Allergies are often associated with ocular surface diseases and in particular with dry eye syndrome. Reduced quantity or quality of tears increases the number of allergens, limits...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

When are glucocorticoids harmful for the eye?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The glucocorticosteroids are medications showing high effectiveness in the treatment of many systemic diseases having an immunological basis, in particular of allergic diseases. Cataract and glaucoma are serious complications of taking local and general GKS. Both these diseases cause considerable visual impairment, and glaucoma can lead to permanent damage of the optic nerve. The adverse reactions depend on several factors: the kind of preparation, the dose, the duration of treatment of disease, and individual factors including age, sex, genetic predisposition and interaction with different medications. Glaucoma or lenticu...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Allergy and contact lensesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Ocular allergy and contact lens wear affect a large percentage of the population, the implications for interaction of allergy and changes induced by contact lens wear are significant. To present all about allergic conditions in general and ophthalmic allergies in particular, and how these can affect contact lens wear. It suggests solutions that can be followed in order to alleviate problems that can arise during contact lens use and suggests ways of overcoming the allergic symptoms and signs. Studies proving the healthiest and the most comfortable way of contact lens wear is the daily disposables are also presented. Nowada...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Status asthmaticus in the past and nowadaysEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The problem of status asthmaticus in the past and nowadays is discussed. This phenomenon in the recent period has diminished markedly. (Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house)
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Severe persistent allergic asthmaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Asthma is a chronic inflammatory disease of the airways. Approximately 60% of asthma cases can be attributed to allergic asthma. The aim of this article is to present the current results concerning the problem of severe persistent allergic asthma, the use of anti-IgE treatment (omalizumab) as well as our own results determining the clinical efficacy and anti-inflammatory activity of Xolair (omalizumab) in patients with severe allergic asthma. (Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house)
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Chronic urticaria – difficult clinical problem. What more can be done?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Numerous factors are proposed to be responsible for chronic urticaria (CU) manifestation. No aetiology is fund in many cases of the diseases in spite of many diagnostic tests available. Chronic urticaria and particularly idiopathic one is extremely disabling and can be difficult to treat. Although it is unusual to identify underlying specific precipitating factors mast cell degranulation is of central importance in the pathogenesis of CU. Update consensus highlights the current achievements in this field concerning both diagnostic procedures and methods of management. The cornestone of CU therapy are antihistaminics which ...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

X MIĘDZYNARODOWY KONGRES POLSKIEGO TOWARZYSTWA ALERGOLOGICZNEGO Reminiscence on the polish allergologyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house)
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Review paper The most common diseases of scalp in childhoodEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The total and partial lack of hair growth occurs in the form of several clinical forms, either as an isolated defect or in connection with many kinds of abnormalities. Logical classification should be based on careful histopathological and genetic studies, but such studies are, unfortunately, rarely carried out. Hair microscopic examination is necessary in cases of abnormal hair, regardless of the quantitative which was on the scalp and it should be carefully sought for other ektodermal defects and examination of the patients relatives. Congenital alopecia may be partial or total. I the moment of the damage the condition o...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Review paper Skin tests with native alimentary allergens in the diagnostics of food allergyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Despite continuous progress in the field of medical sciences, diagnostics of food allergy remains a difficult issue. First of all in order to diagnose food allergy specific elimination diet should be applied to the patient and accurate clinical examination followed by various diagnostic tests should be performed in order to exclude more probable causes of symptoms observed and decrease the risk of unnecessary, strict elimination diets. Double blind placebo controlled food challenge (DBPCFC) remains a golden standard in the diagnostics of food allergy. In cases when DBPCFC is difficult to perform, tests with native food all...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Case report Erythema nodosum coexisting with ascariasis and pulmonary Chlamydia pneumoniae infection – case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Erythema nodosum belongs to a group of relatively common hypodermis inflammation. It occurs mainly among women and particularly affects young ones. The etiology of the disease is not clear. Most frequently the changes appear on the surface of the front part of shank. Initially, red nodules change their color into dark brown and then into yellow and green color. Exanthema undergo neither dissolution nor cicatrisation. Regression is frequent. The case of erythema nodosum we presented, caused by Ascaris lumbricoides infection as well as by an early Chlamydia pneumoniae infection, is numbered as rarely described in literature....
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - October 19, 2009 Category: Dermatology Source Type: journals

Case report Urticaria vasculitis in the course of subacute cutaneous erythematosus – case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Subacute cutaneous lupus erythematosus (SCLE) is a non-scarring, non-atrophy-producing disease, with significant photosensitization. Even though during the course of the disease systemic symptoms are observed (subfebrile body temperature, myalgia, arthralgia), SCLE usually does not involve the kidneys. Furthermore, in some patients SCLE may be induced by drugs (antihypertensive agents, terbinafine). Urticarial vasculitis is a sort of chronic autoimmune urticaria resulting from vascular disorders, associated with immune complexes deposition and inflammatory cell infiltration around vessels (type III immune reaction accordin...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - August 30, 2009 Category: Dermatology Source Type: journals

Case report Transient manifestation of dermatitis herpetiformis in a female with familial predisposition induced by propafenoneEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Dermatitis herpetiformis (DH) is an autoimmune blistering disorder pathogenetically associated with a gluten-dependent enteropathy. It is characterized by intensively pruritic, symmetrically distributed papulovesicular lesions found mainly on the extensor surfaces of the forearms, elbows, knees and gluteal region. Familial occurrence is frequently observed. Many drugs and chemical substances are triggers of the disease. In the paper the case of a 29-year-old woman with DH induced by propafenone and a positive familial history of DH is described. (Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house)
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - August 30, 2009 Category: Dermatology Source Type: journals

Case report Reccurrent neurotrophic ulcerations in a patient with meningomyelocele – case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present a case of a 29-year old woman with spina bifida and inherent myelomeningocele of the lumbo-sacral region of the spinal column, in whom from early childhood non-painful and non-healing erosions and deep ulcerations appeared within the left foot due to small injuries. Multi-annual inefficacious treatment and lack of proper diagnosis precluded the correct causal treatment and led to amputation of the 5th toe of the left foot, osteolytic changes in the metatarsal bones, and finally to a life-threatening condition (Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house)
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - August 30, 2009 Category: Dermatology Source Type: journals

Case report Conglobate acne in a pregnant woman – an important therapeutic problem. A case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A case of a 29-year-old pregnant woman suffering from conglobate acne that appeared in the 1st trimester is presented. The influence of pregnancy on the course of acne as well as limitation of anti-acne treatment is discussed. The severe course of acne in this patient required systemic antibiotic treatment followed by laser therapy to correct post-inflammatory lesions. (Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house)
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - August 30, 2009 Category: Dermatology Source Type: journals

Case report Behçet disease – case report and reviewEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a rare case of Behçet’s disease in a Caucasian man. Behçet’s disease is a chronic recurrent generalized vasculitis whose manifestation seems to be dependent on genetic predisposition triggered by environmental factors. It occurs endemically in central and eastern Asia. Dermatological symptoms are most common, including recurrent oral and genital aphthous ulcers. Severe ocular inflammation can lead to permanent impairment of vision. The involvement of other organ systems can potentially lead to life-threatening complications. We discuss the course of the disease, the clinical symptoms, the diagnostic...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - August 30, 2009 Category: Dermatology Source Type: journals

Review paper Aetiopathogenesis, clinical picture and treatment of vitiligoEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Vitiligo is a common idiopathic depigmentary skin disorder, characterized by destruction of melanocytes, which has been reported in about 0.5-4% of the global population. The pathogenesis of vitiligo is still unclear. There are some theories regarding the mechanism of melanocyte dysfunction and disappearance (autoimmune, neural, self-destruction, oxidant and melanocytorrhagy). Treatment is difficult, prolonged and usually disappointing. An important part of therapy should involve proper education of the patient concerning not only medical methods, but also camouflage and often psychotherapy. (Source: Articles of Advances i...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - August 30, 2009 Category: Dermatology Source Type: journals

Review paper Genital ulcer diseases as an entry for HIV infectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Genital ulcer diseases (GUDs) are documented agents facilitating HIV-1 infection. The main pathogens causing GUDs are: Herpes simplex virus (HSV), Treponema pallidum and Haemophilus ducreyi. It is suggested that these diseases may increase the risk of HIV transmission even a hundredfold. A few mechanisms facilitating HIV penetration into the organism are considered. The first one is disruption of the epidermis or mucous membranes, creating a physical entry point for an infection. The next one is an increased number of inflammatory infiltration cells such as macrophages and T-lymphocytes. Increased expression (up-regulation...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - August 30, 2009 Category: Dermatology Source Type: journals

Review paper Co-morbidity of depression, anxiety disorders and cognitive function impairment among patients suffering from chronic obstructive pulmonary diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Chronic respiratory system diseases are a serious public health issue all over the world. Chronic obstructive pulmonary disease (COPD) is one of the most frequent pulmonary diseases. Chronic obstructive pulmonary disease limits to a wide extent patients’ everyday functioning in physical, emotional and social aspects. It is the reason for the decrease in patients’ quality of life. Not many reports, especially Polish studies, are concerned with COPD’s influence on emotional and cognitive functioning. The aim of the study is to present the co-morbidity of depression, anxiety disorders and cognitive impairmen...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - August 30, 2009 Category: Dermatology Source Type: journals

Original paper Photodynamic diagnosis of skin cancers – own experiencesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The method of photodynamic diagnostics does not replace the necessity of performing histopathological examinations, which still are of basic importance, but the places of affected skin specimen sampling may be determined by a non-invasive method. Moreover, the method of so-called “optic biopsy”, supplementing diagnostic investigations by determining the precise boundary line of the change, enables first of all total tumour excision, obtaining simultaneously an optimal cosmetic effect, particularly in the case of superficial changes. (Source: Articles of Advances in Dermatology and Allergology - TER...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - August 30, 2009 Category: Dermatology Source Type: journals

Original paper Primary skin cancers – results of photodynamic therapyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Photodynamic diagnosis and therapy of tumours is a new procedure utilizing the combined action of light and a photosensitizing drug. The laser-fibre optic delivery system allows the visualization and treatment of superficial and deeply located neoplasms including malignancies of the skin, head and neck, oesophagus, endobronchial tract, stomach, urinary bladder, female genital tract and other sites. The putative action mechanism depends on evocation of fluorescence of a photosensitizing drug within cancer tissue (important for non-invasive optical diagnosis) and involves photochemical destruction of tumour tissue membranes ...
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - August 30, 2009 Category: Dermatology Source Type: journals

Original paper Health self conciousness of the general practitioner’s and oncologist’s patients in relations to melanocytic lesions and melanomaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The aim of this article is to sum up level of health consciousness of general practitioners and oncologists patients about naevus and malignant melanoma. Although melanomas are rare lesions in many countries worldwide, every 10 years the number of melanoma has doubled. General practitioners and oncologists play a basic role in primary strategy to avoid risk factors to develop lesions and to detect melanoma at an early stage. (Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house)
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - August 30, 2009 Category: Dermatology Source Type: journals

Original paper Angiogenesis assessment in patients with mycosis fungoidesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The studied factor does not fulfil the criteria for a biomarker distinguishing mycosis fungoides and parapsoriasis en grandes plaques, despite being a characteristic feature of advanced mycosis fungoides, and increased angiogenesis measured by CD34 expression is a poor prognostic marker of the disease. (Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house)
Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house - August 30, 2009 Category: Dermatology Source Type: journals