Practical considerations for clinicians for transitioning patients on maintenance therapy with olaparib capsules to the tablet formulation of olaparib
AbstractPurposeOlaparib was originally formulated as 50  mg capsules with a recommended dose of 400 mg twice daily which requires patients to take 16 capsules a day. More recently, a tablet formulation with equivalent efficacy has become available and reduces the pill burden for patients to two tablets twice daily which is more convenient for patients. However, it is important to understand the key differences between the olaparib capsule and tablet formulations as they are not bioequivalent, and the doses are not interchangeable. Educating patients when transitioning from capsules to tablets is critical to avoid dosing ...
Source: Asia-Pacific Journal of Clinical Oncology - November 26, 2018 Category: Cancer & Oncology Authors: Michael Friedlander, Catherine Shannon, Jeffrey Goh, Clare Scott, Linda Mileshkin Tags: GUIDELINES/CONSENSUS Source Type: research

Receipt of radiotherapy after mastectomy in women with breast cancer: Population ‐based cohort study in New Zealand
ConclusionDisparities exist in the receipt of PMRT in breast cancer patients in New Zealand, underscoring the need for a greater equity focus in management of breast cancer. (Source: Asia-Pacific Journal of Clinical Oncology)
Source: Asia-Pacific Journal of Clinical Oncology - November 15, 2018 Category: Cancer & Oncology Authors: Phyu Mon Latt, Sandar Tin Tin, Mark Elwood, Ross Lawrenson, Ian Campbell Tags: ORIGINAL ARTICLE Source Type: research

Real ‐world efficacy and toxicity of combined nivolumab and ipilimumab in patients with metastatic melanoma
ConclusionIn this study, responses to combination immunotherapy were lower than reported. Patients treated with prior immunotherapy had similar responses as treatment ‐naïve pts. The toxicity profile seen in this study is similar to those reported in clinical trials. (Source: Asia-Pacific Journal of Clinical Oncology)
Source: Asia-Pacific Journal of Clinical Oncology - November 13, 2018 Category: Cancer & Oncology Authors: Sagun Parakh, Manreet Randhawa, Bella Nguyen, Lydia Warburton, Mohammad Akhtar Hussain, Jonathan Cebon, Michael Millward, Desmond Yip, Sayed Ali Tags: ORIGINAL ARTICLE Source Type: research

The potential “additive” thromboembolic risk of radiotherapy
Asia-Pacific Journal of Clinical Oncology, EarlyView. (Source: Asia-Pacific Journal of Clinical Oncology)
Source: Asia-Pacific Journal of Clinical Oncology - November 13, 2018 Category: Cancer & Oncology Authors: Marliese Alexander, Rebekka Sryjanen, David Ball, Michael MacManus, Kate Burbury Tags: LETTER TO THE EDITOR Source Type: research

Prognostic significance of BRAF mutation alone and in combination with microsatellite instability in stage III colon cancer
ConclusionBRAF ‐mutated cancers demonstrated a trend toward poorer outcomes, however, when adjusted for clinicopathological factors and chemotherapy, BRAF mutation was not found to be an independent prognostic biomarker in stage III colon cancer, even when combined with MSI. (Source: Asia-Pacific Journal of Clinical Oncology)
Source: Asia-Pacific Journal of Clinical Oncology - November 13, 2018 Category: Cancer & Oncology Authors: Hanumant Chouhan, Tarik Sammour, Michelle L. Thomas, James W. Moore Tags: ORIGINAL ARTICLE Source Type: research

Favorable 10 ‐year outcomes of image‐guided intensity‐modulated radiotherapy combined with long‐term androgen deprivation for Japanese patients with nonmetastatic prostate cancer
ConclusionsThis study suggest that high ‐dose IG‐IMRT combined with long‐term ADT is effective and implementable, leading to excellent 10‐year outcomes for Japanese patients with nonmetastatic prostate cancer. (Source: Asia-Pacific Journal of Clinical Oncology)
Source: Asia-Pacific Journal of Clinical Oncology - November 8, 2018 Category: Cancer & Oncology Authors: Natsuo Tomita, Norihito Soga, Yuji Ogura, Jun Furusawa, Hiroshi Tanaka, Yutaro Koide, Hiroyuki Tachibana, Takeshi Kodira Tags: ORIGINAL ARTICLE Source Type: research

Association between PD ‐L1 expression and lymph node metastasis in cutaneous squamous cell carcinoma
ConclusionsThe results suggested that high intensity of PD ‐L1 expression in TCs is associated with lymph node metastasis in cSCC. (Source: Asia-Pacific Journal of Clinical Oncology)
Source: Asia-Pacific Journal of Clinical Oncology - November 8, 2018 Category: Cancer & Oncology Authors: Shiori Kamiya, Junji Kato, Takafumi Kamiya, Toshiharu Yamashita, Yasuyuki Sumikawa, Tokimasa Hida, Kohei Horimoto, Sayuri Sato, Hitomi Takahashi, Masahide Sawada, Terufumi Kubo, Toshihiko Torigoe, Hisashi Uhara Tags: ORIGINAL ARTICLE Source Type: research

Author index
Asia-Pacific Journal of Clinical Oncology,Volume 14, Issue S7, Page 203-212, November 2018. (Source: Asia-Pacific Journal of Clinical Oncology)
Source: Asia-Pacific Journal of Clinical Oncology - October 30, 2018 Category: Cancer & Oncology Source Type: research

Poster abstracts
Asia-Pacific Journal of Clinical Oncology,Volume 14, Issue S7, Page 91-202, November 2018. (Source: Asia-Pacific Journal of Clinical Oncology)
Source: Asia-Pacific Journal of Clinical Oncology - October 30, 2018 Category: Cancer & Oncology Source Type: research

Oral abstracts
Asia-Pacific Journal of Clinical Oncology,Volume 14, Issue S7, Page 50-90, November 2018. (Source: Asia-Pacific Journal of Clinical Oncology)
Source: Asia-Pacific Journal of Clinical Oncology - October 30, 2018 Category: Cancer & Oncology Source Type: research

Program in detail
Asia-Pacific Journal of Clinical Oncology,Volume 14, Issue S7, Page 25-49, November 2018. (Source: Asia-Pacific Journal of Clinical Oncology)
Source: Asia-Pacific Journal of Clinical Oncology - October 30, 2018 Category: Cancer & Oncology Source Type: research

National speakers
Asia-Pacific Journal of Clinical Oncology,Volume 14, Issue S7, Page 9-20, November 2018. (Source: Asia-Pacific Journal of Clinical Oncology)
Source: Asia-Pacific Journal of Clinical Oncology - October 30, 2018 Category: Cancer & Oncology Source Type: research

2018 cosa asm exhibitor profiles
Asia-Pacific Journal of Clinical Oncology,Volume 14, Issue S7, Page 215-218, November 2018. (Source: Asia-Pacific Journal of Clinical Oncology)
Source: Asia-Pacific Journal of Clinical Oncology - October 30, 2018 Category: Cancer & Oncology Source Type: research

Sponsors acknowledgements
Asia-Pacific Journal of Clinical Oncology,Volume 14, Issue S7, Page 24-24, November 2018. (Source: Asia-Pacific Journal of Clinical Oncology)
Source: Asia-Pacific Journal of Clinical Oncology - October 30, 2018 Category: Cancer & Oncology Source Type: research

International speakers
Asia-Pacific Journal of Clinical Oncology,Volume 14, Issue S7, Page 7-8, November 2018. (Source: Asia-Pacific Journal of Clinical Oncology)
Source: Asia-Pacific Journal of Clinical Oncology - October 30, 2018 Category: Cancer & Oncology Source Type: research