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Pulmonary fungal infection with hyalohyphomycosis associated with zygomycosis and Actinomyces spp. in a patient with ankylosing spondylitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A espondilite anquilosante (EA) pode cursar com manifestações extra-articulares e, dentre elas, as pulmonares. A fibrose nos ápices pulmonares ocorre em até 30% dos casos e as formações císticas são menos frequentes e observadas em casos avançados. A colonização dessas cavidades é uma complicação rara. Um paciente com diagnóstico de EA desde 1998, com comprometimento axial, histórico de tuberculose pulmonar tratada em 2002 e 2007, evoluiu com um quadro de aspergilose bilateral em ápices pulmonares associada à zigomicose e Actinomyces spp. Havia sido internado para investigar queixa de emagrecimento, sudor...
Source: Revista Brasileira de Reumatologia - November 20, 2009 Category: Rheumatology Source Type: journals

ErrataEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A espondilite anquilosante (EA) pode cursar com manifestações extra-articulares e, dentre elas, as pulmonares. A fibrose nos ápices pulmonares ocorre em até 30% dos casos e as formações císticas são menos frequentes e observadas em casos avançados. A colonização dessas cavidades é uma complicação rara. Um paciente com diagnóstico de EA desde 1998, com comprometimento axial, histórico de tuberculose pulmonar tratada em 2002 e 2007, evoluiu com um quadro de aspergilose bilateral em ápices pulmonares associada à zigomicose e Actinomyces spp. Havia sido internado para investigar queixa de emagrecimento, sudor...
Source: Revista Brasileira de Reumatologia - November 20, 2009 Category: Rheumatology Source Type: journals

Complement induction and complement evasion in patients with cerebral aspergillosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Rambach G, Maier H, Vago G, Mohsenipour I, Lass-Flörl C, Defant A, Würzner R, Dierich MP, Speth C (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - November 19, 2009 Category: Respiratory Medicine Source Type: consumer

Antifungal activity of the local complement system in cerebral aspergillosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Rambach G, Hagleitner M, Mohsenipour I, Lass-Flörl C, Maier H, Würzner R, Dierich MP, Speth C (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - November 19, 2009 Category: Respiratory Medicine Source Type: consumer

Aspergillosis: a limiting factor during recovery of captive magellanic penguinsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Xavier MO, Soares MP, Meinerz ARM, Nobre MO, Osorio LG, da Silva Filho RP, Meireles MCA (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - November 19, 2009 Category: Respiratory Medicine Source Type: consumer

Polymicrobial lung infection in postrenal transplant recipient diagnosed by fine-needle aspiration cytologyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a case of concomitant pulmonary cryptococcosis, aspergillosis, and tuberculosis in a renal transplant recipient diagnosed on FNAC.A 50-year-old renal transplant recipient, asymptomatic for 3 year, presented with intermittent low-grade fever associated with cough, expectoration, and a newly developed cavitatory lesion in the left lung on chest X-ray. Computed tomography-guided FNAC performed on the lung lesion showed fungal profiles with septate hyphae and acute-angled branching consistent with morphology of Aspergillus. In addition, numerous yeast forms of cryptococcus and a few acid-fast mycobacterial tubercle b...
Source: Diagnostic Cytopathology - November 19, 2009 Category: Pathology Authors: Rajan Duggal, Arvind Rajwanshi, Nalini Gupta, Anupam Lal, Manphool Singhal Source Type: journals

Role of macrophages in host defense against aspergillosis and strategies for immune augmentationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Segal BH. (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - November 18, 2009 Category: Respiratory Medicine Source Type: consumer

Can serum mannose-binding lectin levels aid with the diagnosis of invasive aspergillosis?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Kalil AC (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - November 18, 2009 Category: Respiratory Medicine Source Type: consumer

Association of mannose-binding lectin deficiency with acute invasive aspergillosis in immunocompromised patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Lambourne J, Agranoff D, Herbrecht R, Troke PF, Buchbinder A, Willis F, Letscher-Bru V, Agrawal S, Doffman S, Johnson E, White PL, Barnes RA, Griffin G, Lindsay JA, Harrison TS (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - November 18, 2009 Category: Respiratory Medicine Source Type: consumer

Evaluation of the expression of TLR-2, Dectin-1 and TNF-α level in invasive aspergillosis in cancer miceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, we explored whether the innate resistance to IA in cancer mice has resulted in altered expression of TLR-2 and Dectin-1 in macrophages (flow cytometry) and production of tumour necrosis factor alpha (TNF-α; ELISA) as well as overall mortality. The data demonstrated significant increases in Dectin-1 and TLR-2 on peritoneal macrophages and mortality in cancer mice intravenously infected with A. fumigatus. TNF-α levels were not significantly increased in this group. Probably, IA causes some disorganization in inflammatory responses. We hypothesize that concomitance of IA and cancer may change the micro-en...
Source: Comparative Clinical Pathology - November 17, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

[] Azole resistance in Aspergillus fumigatus: a side-effect of environmental fungicide use?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Invasive aspergillosis due to multi-azole-resistant Aspergillus fumigatus has emerged in the Netherlands since 1999, with 6·0–12·8% of patients harbouring resistant isolates. The presence of a single resistance mechanism (denoted by TR/L98H), which consists of a substitution at codon 98 of cyp51A and a 34-bp tandem repeat in the gene-promoter region, was found in over 90% of clinical A fumigatus isolates. This is consistent with a route of resistance development through exposure to azole compounds in the environment. Indeed, TR/L98H A fumigatus isolates were cultured from soil and compost, were shown to be cross-resist...
Source: The Lancet Infectious Diseases - November 16, 2009 Category: Infectious Diseases Authors: Paul E Verweij, Eveline Snelders, Gert HJ Kema, Emilia Mellado, Willem JG Melchers Source Type: journals

Efficacy of Posaconazole against three clinical Aspergillus fumigatus Isolates with Mutations in the cyp51A Gene.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The in-vivo efficacy of posaconazole against 4 clinical Aspergillus fumigatus isolates with posaconazole MICs ranging from 0.03 to 16 mg/L, as determined with the CLSI-M38A method, was assessed in a nonneutropenic murine model of disseminated aspergillosis. Underlying resistance mechanisms of the isolates included substitutions in the cyp51A gene at codon 220 (M220I), codon 54 (G54W) and codon 98 (L98H). The latter was combined with a 34 bp tandem repeat in the gene promoter region (TR/L98H). The control isolate exhibited a wild type phenotype without any known resistance mechanism. Oral posaconazole therapy was starte...
Source: Antimicrobial Agents and Chemotherapy - November 16, 2009 Category: Microbiology Authors: Mavridou E, Brüggemann RJ, Melchers WJ, Mouton JW, Verweij PE Tags: Antimicrob Agents Chemother Source Type: journals

Diabetes as a Determinant of Mortality in Cystic Fibrosis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Background: Diabetes is increasingly common in cystic fibrosis (CF), but little exists describing its influence on mortality. Using national UK data, this study documents diabetes-specific mortality rates, estimates the impact of diabetes on survival, and estimates population attributable fractions. Methods: This retrospective cohort study identified 8,029 individuals aged 0-65 years from the UK CF Registry (1996-2005). 5,892 patients were included in analyses of mortality rates and 4,234 in analyses of risk factors. We calculated age-adjusted mortality rates using Poisson regression, standardized mortality ratios usin...
Source: Diabetes Care - November 16, 2009 Category: Endocrinology Authors: Chamnan P, Shine BS, Haworth CS, Bilton D, Adler AI Tags: Diabetes Care Source Type: journals

Disseminated aspergillosis during treatment of hepatic failureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Enberg R, Bletzinger R, Burry VF (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - November 11, 2009 Category: Respiratory Medicine Source Type: consumer

Disseminated aspergillosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Burke BJ, Storring FK, Parry TE (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - November 11, 2009 Category: Respiratory Medicine Source Type: consumer

Disseminated aspergillosis in a premature neonateEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Meessen NE, Oberndorff KM, Jacobs JA (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - November 11, 2009 Category: Respiratory Medicine Source Type: consumer

An EORTC Phase II study of caspofungin as first-line therapy of invasive aspergillosis in haematological patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Caspofungin provided an observed response rate compatible with the null hypothesis of a true response rate of ≤35%. Underlying disease-related factors had a major impact on results. (Source: Journal of Antimicrobial Chemotherapy)
Source: Journal of Antimicrobial Chemotherapy - November 10, 2009 Category: Microbiology Authors: Viscoli, C., Herbrecht, R., Akan, H., Baila, L., Sonet, A., Gallamini, A., Giagounidis, A., Marchetti, O., Martino, R., Meert, L., Paesmans, M., Ameye, L., Shivaprakash, M., Ullmann, A. J., Maertens, J., on behalf of the Infectious Disease Group of the EO Tags: Original research Source Type: journals

Pulmonary aspergillosis in patients with chronic obstructive pulmonary disease: incidence, risk factors, and outcomeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe a large series of patients with chronic obstructive pulmonary disease (COPD) and probable invasive pulmonary aspergillosis (IPA), and the risk factors and incidence of the disease in patients with isolation of Aspergillus from lower respiratory tract samples. From 2000 to 2007, we retrospectively studied all patients admitted with COPD and isolation of Aspergillus (239; 16.3/1000 admissions). Multivariate logistic regression and survival curves were used. Fifty-three patients had probable IPA (3.6 cases of IPA per 1000 COPD admissions). IPA affects at least 22.1% of patients with COPD and isolation of Aspergill...
Source: Clinical Microbiology and Infection - November 10, 2009 Category: Microbiology Authors: J. Guinea, M. Torres-Narbona, P. Gijón, P. Muñoz, F. Pozo, T. Peláez, J. de Miguel, E. Bouza Source Type: journals

Bronchoalveolar Lavage Fluid Galactomannan for the Diagnosis of Invasive Pulmonary Aspergillosis in Patients with Hematologic DiseasesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Maertens J, Maertens V, Theunissen K, Meersseman W, Meersseman P, Meers S, Verbeken E, Verhoef G, Van Eldere J, Lagrou K (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - November 7, 2009 Category: Respiratory Medicine Source Type: consumer

Invasive aspergillosis in patients with acute myeloid leukemia: SEIFEM-2008 registry studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Pagano L, Caira M, Candoni A, Offidani M, Martino B, Specchia G, Pastore D, Stanzani M, Cattaneo C, Fanci R, Caramatti C, Rossini F, Luppi M, Potenza L, Ferrara F, Mitra ME, Fadda RM, Invernizzi R, Aloisi T, Picardi M, Bonini A, Vacca A, Chierichini A, Melillo L, de Waure C, Fianchi L, Riva M, Leone G, Aversa F, Nosari A. (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - November 6, 2009 Category: Respiratory Medicine Source Type: consumer

An EORTC Phase II study of caspofungin as first-line therapy of invasive aspergillosis in haematological patients.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Viscoli C, Herbrecht R, Akan H, Baila L, Sonet A, Gallamini A, Giagounidis A, Marchetti O, Martino R, Meert L, Paesmans M, Ameye L, Shivaprakash M, Ullmann AJ, Maertens J; on behalf of the Infectious Disease Group of the EORTC. (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - November 6, 2009 Category: Respiratory Medicine Source Type: consumer

Contribution of galactomannan antigen detection in bronchoalveolar lavage to the diagnosis of invasive pulmonary aspergillosis in patients with hematologic malignanciesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Bergeron A, Belle A, Sulahian A, Lacroix C, Chevret S, Raffoux E, Arnulf B, Socié G, Ribaud P, Tazi A (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - November 6, 2009 Category: Respiratory Medicine Source Type: consumer

Donor-derived aspergillosis from use of a solid organ recipient as a multiorgan donorEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Mueller NJ, Weisser M, Fehr T, Wüthrich RP, Müllhaupt B, Lehmann R, Imhof A, Aubert JD, Genoni M, Kunz R, Weber M, Steiger J (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - November 6, 2009 Category: Respiratory Medicine Source Type: consumer

Clinical significance of decline in serum IgE levels in allergic bronchopulmonary aspergillosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Agarwal R, Gupta D, Aggarwal AN, Saxena AK, Saikia B, Chakrabarti A, Jindal SK (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - November 6, 2009 Category: Respiratory Medicine Source Type: consumer

Detection of Invasive Pulmonary Aspergillosis by Lateral Flow Technology Compared to Galactomannan and (1->3)-{beta}-D-GlucanEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Wiederhold NP, Thornton CR, Najvar LK, Kirkpatrick WR, Bocanegra R, Patterson TF (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - November 6, 2009 Category: Respiratory Medicine Source Type: consumer

Vertebral osteomyelitis with a rare etiology diagnosed by fine-needle aspiration cytologyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report one such case of vertebral osteomyelitis due to Aspergillus diagnosed by FNAC in a well-controlled diabetic patient who presented with nonspecific symptoms and in whom a clinical and radiological diagnosis of Pott's spine was considered. The present case stresses the importance of early cytologic diagnosis of vertebral Aspergillus osteomyelitis, which in conjunction with appropriate timely medical and surgical treatment, offers good recovery without much sequelae or threat to life. Diagn. Cytopathol. 2010. © 2009 Wiley-Liss, Inc. (Source: Diagnostic Cytopathology)
Source: Diagnostic Cytopathology - November 5, 2009 Category: Pathology Authors: BN Nandeesh, Usha Kini, Betty Alexander Source Type: journals

Molecular Epidemiology of Invasive Aspergillosis: Lessons Learned from an Outbreak Investigation in an Australian Hematology Unit • Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Infection Control and Hospital Epidemiology, Volume 30, Issue 12, Page 1223-1226, December 2009. Suspected nosocomial Aspergillus fumigatus infections in an Australian hematology unit were investigated by molecular typing of clinical and environmental isolates using polymerase chain reaction fingerprinting, CSP typing, and multilocus microsatellite typing. Only multilocus microsatellite typing revealed that all isolates were genetically distinct. The selection of an appropriate typing method is essential for effective outbreak investigations. (Source: Infect Control Hosp Epidemiol Latest Issue)
Source: Infect Control Hosp Epidemiol Latest Issue - November 4, 2009 Category: Epidemiology Tags: article CONCISE COMMUNICATION Source Type: journals

Rhino-orbital mucormycosis and aspergillosis: differences in outcome, clinical and imaging characteristicsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Content Type Journal ArticleCategory Letter to the EditorDOI 10.1007/s00405-009-1136-zAuthors Suneetha Nithyanandam, St John’s Medical College Department of Ophthalmology Sarjapur Road Bangalore 560005 IndiaMarjorie A. Correa, St John’s Medical College Department of Pathology Bangalore India Journal European Archives of Oto-Rhino-LaryngologyOnline ISSN 1434-4726Print ISSN 0937-4477 (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - November 4, 2009 Category: ENT & OMF Tags: European Archives of Oto-Rhino-Laryngology Source Type: journals

Bronchoalveolar Lavage Fluid Galactomannan for the Diagnosis of Invasive Pulmonary Aspergillosis in Patients with Hematologic DiseasesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. BAL GM is a valuable adjunctive diagnostic tool to other conventional microbiologic and radiologic studies. (Source: Clinical Infectious Diseases Latest Issue)
Source: Clinical Infectious Diseases Latest Issue - November 3, 2009 Category: Infectious Diseases Tags: article MAJOR ARTICLE Source Type: journals

Sinus aspergilloma in rheumatoid arthritis before or during tumor necrosis factor-alpha antagonist therapyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Otorhinolaryngological symptoms must be evaluated before starting or switching TNF-alpha antagonists. Routine computed tomography of the sinuses before starting or switching TNF-alpha antagonists may deserve consideration. (Source: BioMed Central)
Source: BioMed Central - November 3, 2009 Category: Journals (General) Authors: Ariane LeboimeJean-Marie BerthelotYannick AllanoreLama Khalil-KallouchePhilippe HermanPhilippe OrcelFrederic Liote Source Type: journals

Invasive Aspergillosis in Italian AIDS patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Libanore M, Prini E, Mazzetti M, Barchi E, Raise E, Gritti FM, Bonazzi L, Ghinelli F (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - November 3, 2009 Category: Respiratory Medicine Source Type: consumer

Clinical manifestations and diagnosis of invasive aspergillosis in immunocompromised childrenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Müller FM, Trusen A, Weig M (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - November 3, 2009 Category: Respiratory Medicine Source Type: consumer

Itraconazole, an effective adjunctive treatment for allergic bronchopulmonary aspergillosis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report the case of a 21-year old man with a long-standing history of severe asthma and allergic rhinosinusitis who developed progressive worsening of dyspnea, wheezing, productive cough, and nasal obstruction, with little response to antibiotics and repeated short courses of oral corticosteroids. A diagnosis of allergic bronchopulmonary aspergillosis was made on the basis of a combination of clinical, laboratory and radiographic findings.Treatment with oral methylprednisolone and itraconazole resulted in an improvement in symptoms, lung function and computed tomography results, as well as in a decrease in total serum im...
Source: Journal of Investigational Allergology & Clinical Immunology - October 31, 2009 Category: Allergy & Immunology Authors: Santos A, Loureiro G, Faria E, Chieira C Tags: J Investig Allergol Clin Immunol Source Type: journals

Aspergillus and the paediatric lungEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Summary: Aspergillus spp produce a wide range of saprophytic and invasive syndromes in the lungs, including allergic bronchopulmonary aspergillosis (ABPA), aspergilloma and invasive pulmonary aspergillosis (IPA). ABPA results from hypersensitivity to the fungus, and mainly affects patients with asthma or cystic fibrosis (CF). The treatment of choice consists of systemic corticosteroids and itraconazole. Aspergilloma is managed by observation or surgery. IPA is predominantly seen in patients with haematological malignancies, chronic granulomatous disease or immunosuppressive treatment. With the use of aggressive therapies f...
Source: Paediatric Respiratory Reviews - October 30, 2009 Category: Respiratory Medicine Authors: Elpis Hatziagorou, Thomas J. Walsh, John N. Tsanakas, Emmanuel Roilides Tags: Mini-symposium: Fungi and The Paediatric Lung Source Type: journals

Posaconazole reduces infection in AML patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The incidence of pneumonia and invasive pulmonary aspergillosis in acute myeloid leukemia patients was reduced when they were given posaconazole (Noxafil) as prophylaxis. (Source: Cancer Network)
Source: Cancer Network - October 29, 2009 Category: Cancer & Oncology Source Type: info

Treosulfan-based conditioning regimen in a second matched unrelated peripheral blood stem cell transplantation for a pediatric patient with CGD and invasive aspergillosis, who experienced initial graft failure after RIC.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report the case of a 3-year-old boy with CGD, who developed IA despite antifungal prophylaxis. His treatment consisted of a 10-month-long multi-drug antifungal therapy, together with surgery, but these did not cause any substantial clinical improvement. BMT in high-risk patients with CGD remains a challenge due to both, higher risk of graft rejection and inflammatory flare in the course of immune recovery. Our patient rejected the first matched unrelated donor (MUD) allograft after RIC regimen recommended by the EBMT Inborn Errors Working Party for high-risk patients. After treosulfan-based conditioning and second MUD p...
Source: International Journal of Hematology - October 29, 2009 Category: Hematology Authors: Klaudel-Dreszler MA, Kalwak K, Kurenko-Deptuch M, Wolska-Kusnierz B, Heropolitanska-Pliszka E, Pietrucha B, Mikoluc B, Gorczyńska E, Ussowicz M, Chybicka A, Bernatowska E Tags: Int J Hematol Source Type: journals

Editorial Commentary: Can Serum Mannose‐Binding Lectin Levels Aid with the Diagnosis of Invasive Aspergillosis?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Clinical Infectious Diseases, Volume 49, Issue 10, Page 1492-1495, 15 November 2009. (Source: Clinical Infectious Diseases Latest Issue)
Source: Clinical Infectious Diseases Latest Issue - October 27, 2009 Category: Infectious Diseases Tags: article EDITORIAL COMMENTARY Source Type: journals

Antineoplastics: Aspergillosis: case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Reactions)
Source: Reactions - October 26, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals

Pulmonary AspergillosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
George R. Thompson III, M.D. and Thomas F. Patterson, M.D. (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - October 26, 2009 Category: Respiratory Medicine Source Type: consumer

The biocontaminants and complexity of damp indoor spaces: more than what meets the eyesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nine types of biocontaminants in damp indoor environments from microbial growth are discussed: (1) indicator molds; (2) Gram negative and positive bacteria; (3) microbial particulates; (4) mycotoxins; (5) volatile organic compounds, both microbial (MVOCs) and non-microbial (VOCs); (6) proteins; (7) galactomannans; (8) 1-3-β-D-glucans (glucans) and (9) lipopolysaccharides (LPS — endotoxins). When mold species exceed those outdoors contamination is deduced. Gram negative bacterial endotoxins, LPS in indoor environments, synergize with mycotoxins. The gram positive Bacillus species, Actinomycetes (Streptomyces, Noc...
Source: Toxicology and Industrial Health current issue - October 23, 2009 Category: Toxicology Authors: Thrasher, J. D, Crawley, S. Tags: Articles Source Type: journals

Molecular Epidemiology of Invasive Aspergillosis: Lessons Learned from an Outbreak Investigation in an Australian Hematology UnitEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Infection Control and Hospital Epidemiology, Volume 0, Issue 0, Page 000, Latest Articles. Suspected nosocomial Aspergillus fumigatus infections in an Australian hematology unit were investigated by molecular typing of clinical and environmental isolates using polymerase chain reaction fingerprinting, CSP typing, and multilocus microsatellite typing. Only multilocus microsatellite typing revealed that all isolates were genetically distinct. The selection of an appropriate typing method is essential for effective outbreak investigations. (Source: Infect Control Hosp Epidemiol Latest Issue)
Source: Infect Control Hosp Epidemiol Latest Issue - October 22, 2009 Category: Epidemiology Tags: article CONCISE COMMUNICATION Source Type: journals

invasive aspergillosis in patients with acute myeloid leukemia: SEIFEM-2008 registry study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Our series confirms the downward trend in mortality rates reported in previous series, with all new drugs providing similar survival and response rates. Recovery from neutropenia and disease stage are crucial prognostic factors. Efficacious antifungal drugs bridge the gap due to poor hematological and immunological reconstitution. PMID: 19850903 [PubMed - as supplied by publisher] (Source: Haematologica)
Source: Haematologica - October 22, 2009 Category: Hematology Authors: Pagano L, Caira M, Candoni A, Offidani M, Martino B, Specchia G, Pastore D, Stanzani M, Cattaneo C, Fanci R, Caramatti C, Rossini F, Luppi M, Potenza L, Ferrara F, Mitra ME, Fadda RM, Invernizzi R, Aloisi T, Picardi M, Bonini A, Vacca A, Chierichini A, Me Tags: Haematologica Source Type: journals

Fungal infections in hematopoietic stem cell transplantation and solid-organ transplantation - focus on aspergillosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nucci M, Anaissie E (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - October 21, 2009 Category: Respiratory Medicine Source Type: consumer

Approach to the diagnosis of invasive aspergillosis and candidiasisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Wheat LJ (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - October 21, 2009 Category: Respiratory Medicine Source Type: consumer

Impaired interferon-gamma responses, increased interleukin-17 expression, and a tumor necrosis factor-alpha transcriptional program in invasive aspergillosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Armstrong-James DP, Turnbull SA, Teo I, Stark J, Rogers NJ, Rogers TR, Bignell E, Haynes K (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - October 21, 2009 Category: Respiratory Medicine Source Type: consumer

Pseudomembranous Aspergillus tracheobronchitis in a heart transplant recipientEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report the case of a patient who received a heart transplant (HT) because of cardiac amyloidosis and who developed pseudomembranous AT. Possible risk factors concurrent in this case were splenectomy, lymphocytopenia, and previous cytomegalovirus infection. Chest computed tomography scan showed thickening of the left bronchi and a 'tree-in-bud' pattern with multiple small nodules. Bronchoscopic examination revealed raised yellowish pseudomembranous plaques on the tracheobronchial tree. Bronchoalveolar lavage and aspirate cultures yielded Aspergillus fumigatus. The patient recovered with voriconazole. Clinicians should be...
Source: Transplant Infectious Disease - October 21, 2009 Category: Transplant Surgery Authors: A. Ramos, J. Segovia, M. Gómez-Bueno, C. Salas, M.T. Lázaro, I. Sanchez, L. Pulpón Source Type: journals

Detection of sputum Aspergillus galactomannan for diagnosis of invasive pulmonary aspergillosis in haematological patients.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We investigated the diagnostic utility of Aspergillus galactomannan (GM) in sputum for diagnosis of invasive pulmonary aspergillosis (IPA) in haematologic patients and compared the results with those of bronchial lavage fluid (BLF) and serum. Patients were classified into 4 groups using modified European Organization for Research and Treatment of Cancer criteria: group A, proven IPA; group B, probable IPA; group C, possible IPA; group D, others. Groups A and B were considered the IPA group (n = 6); group D was considered non-IPA group (n = 37); group C (n = 13) was equivocal for IPA. As a true negative control, sputa f...
Source: International Journal of Hematology - October 19, 2009 Category: Hematology Authors: Kimura SI, Odawara J, Aoki T, Yamakura M, Takeuchi M, Matsue K Tags: Int J Hematol Source Type: journals

Reconstitution of protection against Aspergillus infection in chronic granulomatous disease (CGD)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Blood)
Source: Blood - October 15, 2009 Category: Hematology Authors: Remijsen, Q., Vandenabeele, P., Willems, J., Kuijpers, T. W. Tags: CORRESPONDENCE Source Type: journals

Response: Protecting against Aspergillus infection in CGDEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Blood)
Source: Blood - October 15, 2009 Category: Hematology Authors: Hakkim, A., Hurwitz, R., Bianchi, M., Brinkmann, V., Siler, U., Seger, R. A., Zychlinsky, A., Reichenbach, J. Tags: CORRESPONDENCE Source Type: journals

Intraspecific Variation and Interspecific Differences in the Bacterial and Fungal Assemblages of Blue Tit (Cyanistes caeruleus) and Great Tit (Parus major) Nests.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Although interest in the relationship between birds and microorganisms is increasing, few studies have compared nest microbial assemblages in wild passerines to determine variation within and between species. Culturing microorganisms from blue tit (Cyanistes caeruleus) and great tit (Parus major) nests from the same study site demonstrated diverse microbial communities with 32 bacterial and 13 fungal species being isolated. Dominant bacteria were Pseudomonas fluorescens, Pseudomonas putida, and Staphylococcus hyicus. Also common in the nests were the keratinolytic bacteria Pseudomonas stutzeri and Bacillus subtilis. Do...
Source: Microbial Ecology - October 14, 2009 Category: Microbiology Authors: Goodenough AE, Stallwood B Tags: Microb Ecol Source Type: journals