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Iron deficiency anemia is not a rare problem among women of reproductive ages in Ethiopia: a community based cross sectional study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Background: In Ethiopia, the existence of iron deficiency anemia is controversial despite the fact that Ethiopia is one of the least developed in Africa with a high burden of nutrient deficiencies. Methods: The first large nutrition study of a representative sample of women in Ethiopia was conducted from June to July 2005 and a systematically selected sub-sample of 970 of these subjects, 15 to 49 years old, were used in this analysis of nutritional anemia. Hemoglobin was measured from capillary blood using a portable HemoCue photometer. For serum ferritin, venous blood from antecubital veins was measured by an automated El...
Source: BMC Blood Disorders - September 6, 2009 Category: Hematology Authors: Jemal HaidarRebecca Pobocik Source Type: journals

The role of religious leaders and faith organisations in haemoglobinopathies - a reviewEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Religious leaders and faith organisations have the potential to influence health education, health promotion and positive health outcomes amongst members of their faith community. They also provide potential access to at-risk populations for increasing awareness about SCD, encouraging health service utilization and ethnic blood donor drives. (Source: BMC Blood Disorders)
Source: BMC Blood Disorders - August 14, 2009 Category: Hematology Authors: Thelma Toni-UebariBaba Inusa Source Type: journals

Profile of Hematological Abnormalities in Indian HIV infected IndividualsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Anemia in HIV patients can be a good clinical indicator to predict and access the underlying immune status. Patients should be investigated for hematological manifestations and appropriate steps should be taken to identify and treat the reversible factors. (Source: BMC Blood Disorders)
Source: BMC Blood Disorders - August 12, 2009 Category: Hematology Authors: Byomakesh DikshitAjay WanchuRavinder SachdevaAman SharmaReena Das Source Type: journals

Application of tri-colour, dual fusion fluorescence in situ hybridization (FISH) system for the characterization of BCR-ABL1 fusion in chronic myelogenous leukaemia (CML) and residual disease monitoringEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Although the D-FISH probe was valuable in establishing the different patterns of aberrant signals and monitoring patients with the classic 2-fusion signals in CML, the tri-colour dual fusion probe should be used for patients with der(9) deletion to monitor response to treatment. (Source: BMC Blood Disorders)
Source: BMC Blood Disorders - July 6, 2009 Category: Hematology Authors: Lisa SiuEdmond MaWai-shan WongMan-hong ChanKit-fai Wong Source Type: journals

Prevalence, phenotype and inheritance of benign neutropenia in ArabsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Arabs have a high prevalence of benign neutropenia that may be inherited as an autosomal dominant trait. (Source: BMC Blood Disorders)
Source: BMC Blood Disorders - March 27, 2009 Category: Hematology Authors: Srdjan Denic, Saad Showqi, Christoph Klein, Mohamed Takala, Nicollas Nagelkerke and Mukesh M Agarwal Source Type: journals

Prevalence, phenotype and inheritance of benign neutropenia in ArabsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Arabs have a high prevalence of benign neutropenia that may be inherited as an autosomal dominant trait. (Source: BMC Blood Disorders)
Source: BMC Blood Disorders - March 27, 2009 Category: Hematology Authors: Srdjan Denic, Saad Showqi, Christoph Klein, Mohamed Takala, Nicolas Nagelkerke and Mukesh M Agarwal Source Type: journals

Factors associated with hospital readmission in sickle cell diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: the results from applying the two models were generally similar, indicating that the findings are not highly sensitive to different approaches. The better fit by the frailty model suggests that there are unmeasured individual factors with impact on hospital readmission. (Source: BMC Blood Disorders)
Source: BMC Blood Disorders - February 27, 2009 Category: Hematology Authors: Monique MORGADO Loureiro, Suely Rozenfeld, Marilia SA Carvalho and Rodrigo DOYLE Portugal Source Type: journals

FIP1L1-PDGFRA molecular analysis in the differential diagnosis of eosinophiliaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: An early diagnosis of FIPIL1-PDGFRA-positive CEL and imatinib treatment offer to the affected patients an excellent clinical therapeutic result, avoiding undesirable morbidity. Moreover, although the molecular mechanisms underlying disease pathogenesis remain to be determined, imatinib can be effective in patients with idiopathic HES. (Source: BMC Blood Disorders)
Source: BMC Blood Disorders - February 2, 2009 Category: Hematology Authors: Gedeon Loules, Fani Kalala, Nikolaos Giannakoulas, Emmanouil Papadakis, Panagiota Matsouka and Matthaios Speletas Source Type: journals

Estimation of transient increases in bleeding risk associated with physical activity in children with haemophiliaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
DiscussionThis case-control study will provide estimates of the risk of participation in vigorous physical activity in children with haemophilia. (Source: BMC Blood Disorders)
Source: BMC Blood Disorders - June 26, 2008 Category: Hematology Authors: Carolyn R Broderick, Robert D Herbert, Jane Latimer, Chris Barnes, Julie A Curtin and Paul Monagle Source Type: journals

Safety of intramuscular influenza vaccine in patients receiving oral anticoagulation therapy: a single blinded multi-centre randomized controlled clinical trialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: This study shows that the intramuscular administration route of influenza vaccine in patients on anticoagulant therapy does not have more side effects than the subcutaneous administration route. (Source: BMC Blood Disorders)
Source: BMC Blood Disorders - May 29, 2008 Category: Hematology Authors: Josep Casajuana, Begona Iglesias, Mireia Fabregas, Francesc Fina, Joan-Antoni Valles, Rosa Aragones, Mencia Benitez and Edurne Zabaleta Source Type: journals

Impact of delayed initiation of erythropoietin in critically ill patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Background: The purpose of this study was to evaluate the impact of recombinant human erythropoietin (rHuEPO) use for anemia of critical illness at a practice site where delayed initiation is common. Methods: Retrospective medical record review involving patients treated with rHuEPO for anemia of critical illness. Those patients given rHuEPO or diagnosed with end-stage renal disease (ESRD) prior to ICU admission were excluded. The primary endpoints were rHuEPO use and RBC transfusion patterns. Results: Complete data were collected for consecutive admissions of 126 patients. Average age (SD) and APACHE II score were 56.5 (...
Source: BMC Blood Disorders - October 4, 2007 Category: Hematology Authors: Jeremiah J Duby, Brian L Erstad, Jacob Abarca, James M Camano, Yvonne Huckleberry and Stuart N Bramblett Source Type: journals

Spontaneous intra-peritoneal bleeding secondary to warfarin, presenting as an acute appendicitis: A case report with the review of literature.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: We recommend the use of the radiological investigations in all the cases of acute abdomen who are on warfarin even if the INR is within the therapeutic range. (Source: BMC Blood Disorders)
Source: BMC Blood Disorders - October 11, 2006 Category: Hematology Authors: Jayesh Sagar, Vikas Kumar, Dharmendra K Shah and Ashok Bhatnagar Source Type: journals

Spontaneous intra-peritoneal bleeding secondary to warfarin, presenting as an acute appendicitis: a case report and review of literatureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: We recommend the use of the radiological investigations in all the cases of acute abdomen who are on warfarin even if the INR is within the therapeutic range. (Source: BMC Blood Disorders)
Source: BMC Blood Disorders - October 11, 2006 Category: Hematology Authors: Jayesh Sagar, Vikas Kumar, Dharmendra K Shah and Ashok Bhatnagar Source Type: journals

Genetic Background Determines Response to Hemostasis and ThrombosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: These results indicate that susceptibility to arterial thrombosis and haemostasis is remarkably different in C57BL/ and A/J mice. Three A/J chromosome substitution strains were identified that expressed a phenotype similar to A/J for rebleeding, the C57Bl/6J background could modify the A/J phenotype, and the combination of two A/J QTL could restore the phenotype. The diverse genetic backgrounds and differences in response to vascular injury induced thrombosis and the tail bleeding assay, suggest the potential for identifying novel genetic determinants of thrombotic risk. (Source: BMC Blood Disorders)
Source: BMC Blood Disorders - October 5, 2006 Category: Hematology Authors: Jane L Hoover-Plow, Aleksey Shchurin, Erika Hart, Jingfeng Sha, Jonathan B Singer, Annie E Hill and Joseph H Nadeau Source Type: journals

Birth characteristics and the risk of childhood leukaemias and lymphomas in New Zealand: a case-control studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: This study showed no positive results though of reasonable size, and its record linkage design minimised bias. Descriptive studies (eg of time trends of ALL) show that environmental factors must be important for some diagnoses. Work has been done on the risk of ALL in relation to chemicals (eg pesticides) and drugs, dietary factors (eg vitamins), electromagnetic fields and infectious hypotheses (to name some); but whether these or other unknown factors are truly important remains to be seen. (Source: BMC Blood Disorders)
Source: BMC Blood Disorders - September 14, 2006 Category: Hematology Authors: Donny IM Wong and John D Dockerty Source Type: journals

Extensive myocardial infiltration by hemopoietic precursors in a patient with myelodysplastic syndromeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
No abstract available (Source: BMC Blood Disorders)
Source: BMC Blood Disorders - September 5, 2006 Category: Hematology Authors: Farrah J Mateen, Sheila R Harding and Anurag Saxena Source Type: journals

The effect of an exercise intervention on aerobic fitness, strength and quality of life in children with haemophilia (ACTRN012605000224628)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study will be the first randomised controlled trial to examine the effects of a structured exercise program on fitness and quality of life in children with haemophilia. (Source: BMC Blood Disorders)
Source: BMC Blood Disorders - May 29, 2006 Category: Hematology Authors: Carolyn R Broderick, Robert D Herbert, Jane Latimer, Julie A Curtin and Hiran C Selvadurai Source Type: journals

An unusual cause of acute abdominal pain – A case presentationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: This case presented to us as an acute abdominal pain. Subsequent investigations revealed the presence of splenic infarction. Coagulation risk factors for thrombosis proved negative. Haematological investigations revealed the presence of anticardiolipin antibodies at the first instance but subsequent determinations were negative. Hence, it mimicked Hughes syndrome initially but the criteria for temporal persistence of anticardiolipin antibody was not fulfilled. Unusual surgical presentation of a thrombotic abnormality as abdominal pain due to splenic infarction. (Source: BMC Blood Disorders)
Source: BMC Blood Disorders - April 7, 2006 Category: Hematology Authors: Rao V Wunnava and Trevor M Hunt Source Type: journals

L-Glutamine therapy reduces endothelial adhesion of sickle red blood cells to human umbilical vein endothelial cellsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: In these studies, oral L-glutamine administration consistently resulted in improvement of sickle RBC adhesion to HUVEC. These data suggest positive physiological effects of L-glutamine in sickle cell disease. (Source: BMC Blood Disorders)
Source: BMC Blood Disorders - July 25, 2005 Category: Hematology Authors: Yutaka Niihara, Neil M Matsui, Yamin M Shen, Dean A Akiyama, Cage S Johnson, M Alenor Sunga, John Magpayo, Stephen H Embury, Vijay K Kalra, Seong Ho Cho and Kouichi R Tanaka Source Type: journals

Total blood lymphocyte counts in hemochromatosis probands with HFE C282Y homozygosity: relationship to severity of iron overload and HLA-A and -B alleles and haplotypesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: We conclude that there is a significant inverse relationship of total blood lymphocyte counts and severity of iron overload in hemochromatosis probands with HFE C282Y homozygosity. The presence of the HLA-A*01 allele or the -B*08 allele was also associated with significantly lower total blood lymphocyte counts, whereas presence of the -B*14 allele was associated with significantly higher total blood lymphocyte counts. In univariate and multivariate analyses, total blood lymphocyte counts were significantly lower in probands with the HLA-A*01-B*08 haplotype than in probands without this haplotype. (Source: BMC Blood Disorders)
Source: BMC Blood Disorders - July 25, 2005 Category: Hematology Authors: James C Barton, Howard W Wiener, Ronald T Acton and Rodney CP Go Source Type: journals

An in vitro evaluation of standard rotational thromboelastography in monitoring of effects of recombinant factor VIIa on coagulopathy induced by hydroxy ethyl starchEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The parameters affected in the ROTEG analysis were Clot Formation Time and Amplitude after 15 minutes while the Clotting Time was unaffected. We believe these effects to be due to methodological problems when using standard activators of the coagulation in the ROTEG analysis in combination with rFVIIa. (Source: BMC Blood Disorders)
Source: BMC Blood Disorders - February 15, 2005 Category: Hematology Authors: Martin Engström, Peter Reinstrup and Ulf Schött Source Type: journals

Lymphocyte subsets in hemophilic patients with hepatitis C virus infection with or without human immunodeficiency virus co-infection: a nested cross-sectional studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: These data support the hypothesis that asymptomatic patients with chronic HCV infection have an altered B-lymphocyte population. (Source: BMC Blood Disorders)
Source: BMC Blood Disorders - January 18, 2005 Category: Hematology Authors: Mingdong Zhang, Thomas R O'Brien, William C Kopp, James J Goedert and for the Multicenter Hemophilia Cohort Study Source Type: journals

Hematopoietic chimerism after allogeneic stem cell transplantation: a comparison of quantitative analysis by automated DNA sizing and fluorescent in situ hybridizationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: All the methods applied enable a rapid and accurate detection of post-HSCT chimerism. (Source: BMC Blood Disorders)
Source: BMC Blood Disorders - January 10, 2005 Category: Hematology Authors: Justyna Jółkowska, Anna Pieczonka, Tomasz Strabel, Dariusz Boruczkowski, Jacek Wachowiak, Peter Bader and Michał Witt Source Type: journals

A randomized trial of washed red blood cell and platelet transfusions in adult acute leukemia [ISRCTN76536440]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: This study provides the first evidence concerning the safety and efficacy of washed platelets, and also raises the possibility of improved survival. We speculate that transfusion of stored red cell and platelet supernatant may compromise treatment, particularly in younger patients with curable disease. Larger trials will be needed to assess this hypothesis. (Source: BMC Blood Disorders)
Source: BMC Blood Disorders - December 10, 2004 Category: Hematology Authors: Neil Blumberg, Joanna M Heal and Jacob M Rowe Source Type: journals

Can mutations in ELA2, neutrophil elastase expression or differential cell toxicity explain sulphasalazine-induced agranulocytosis?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Neutrophil elastase expression and ELA2 mutations do, however, not seem to be involved in the etilogy of sulphasalazine-induced agranulocytosis. Why sulphasalazine is more toxic to promyelocytes than to lymphocytes remains to be explained. (Source: BMC Blood Disorders)
Source: BMC Blood Disorders - December 2, 2004 Category: Hematology Authors: Annica Jacobson, Håkan Melhus and Mia Wadelius Source Type: journals

Effect of splenectomy on type-1/type-2 cytokine gene expression in a patient with adult idiopathic thrombocytopenic purpura (ITP)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The reduction of the Th1/Th2 cytokine ratio that was observed over time after splenectomy was accompanied by full clinical remission. Nevertheless, the persistence of a type-1 polarization, even after several months following spleen removal, is suggestive of a more basic abnormality of the immune function in these patients. (Source: BMC Blood Disorders)
Source: BMC Blood Disorders - October 18, 2004 Category: Hematology Authors: Fotios P Panitsas and Athanasia Mouzaki Source Type: journals

A mutation in a functional Sp1 binding site of the telomerase RNA gene (hTERC) promoter in a patient with Paroxysmal Nocturnal HaemoglobinuriaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: These data are the first report of an hTERC promoter mutation from a patient sample which can modulate core promoter activity in vitro, raising the possibility that the mutation may affect the transcription of the gene in hematopoietic stem cells in vivo, and that dysregulation of telomerase may play a role in the development of bone marrow failure and the evolution of PNH clones. (Source: BMC Blood Disorders)
Source: BMC Blood Disorders - June 22, 2004 Category: Hematology Authors: W Nicol Keith, Tom Vulliamy, Jiangqin Zhao, Cem Ar, Can Erzik, Alan Bilsland, Birsen Ulku, Anna Marrone, Philip J Mason, Monica Bessler, Nedime Serakinci and Inderjeet Dokal Source Type: journals