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41 records returned

Attitudes of dermatologists in the southeastern United States regarding treatment of alopecia areata: a cross-sectional survey study.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Dermatologists' treatment of AA is inconsistent. A stronger evidence base will provide more consistent treatment options. (Source: BMC Dermatology)
Source: BMC Dermatology - November 12, 2009 Category: Dermatology Authors: Niyati MukherjeeDean MorrellMadeleine DuvicPaul StewartLowell Goldsmith Source Type: journals

Professional use of the internet among Saudi Arabian dermatologists: a cross-sectional surveyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Professional medical use of the internet is widespread among dermatologists in Saudi Arabia. Providing access to the internet in the workplace and training of dermatologists to perform effective electronic searches are badly needed to improve the professional medical use of internet, which is expected to lead to better delivery of patient care. (Source: BMC Dermatology)
Source: BMC Dermatology - October 15, 2009 Category: Dermatology Authors: Khalid AlGhamdi Source Type: journals

Volumizing effects of a smooth, highly cohesive, viscous 20-mg/mL hyaluronic acid volumizing filler: prospective European studyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Background: Facial volume loss contributes significantly to facial aging. The 20-mg/mL hyaluronic acid (HA) formulation used in this study is a smooth, highly cohesive, viscous, fully reversible, volumizing filler indicated to restore facial volume. This first prospective study evaluated use in current aesthetic clinical practice. Methods: A pan-European evaluation conducted under guidelines of the World Association of Opinion and Marketing Research, the trial comprised a baseline visit (visit 1) and a follow-up (visit 2) at 14 +/- 7 days posttreatment. Physicians photographed patients at each visit. Each patient was treat...
Source: BMC Dermatology - August 26, 2009 Category: Dermatology Authors: Klaus HoffmannJuvederm Voluma Study Investigators Group (jvsig) Source Type: journals

Familial keloids in five pedigrees: evidence for autosomal dominant inheritance and phenotypic heterogeneityemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Familial keloids most commonly manifest autosomal dominant or semidominant inheritance, and there may be familial patterns of keloid distribution. (Source: BMC Dermatology)
Source: BMC Dermatology - July 27, 2009 Category: Dermatology Authors: Jason ClarkMaria TurnerLillian HowardHoria StanescuRobert KletaJeffrey Kopp Source Type: journals

Role of the EGF +61A>G polymorphism in melanoma pathogenesis: an experience on a large series of Italian cases and controls.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Our findings further suggest that EGF +61A>G polymorphism may have a limited impact on predisposition and/or pathogenesis of melanoma and its prevalence may vary in different populations. (Source: BMC Dermatology)
Source: BMC Dermatology - July 21, 2009 Category: Dermatology Authors: Milena CasulaMauro AlaibacMaria PizzichettaRiccardo BonoPaolo AsciertoIgnazio StanganelliSergio CanzanellaGrazia PalombaEdoardo ZattraThe Italian Melanoma Intergroup (imi)Giuseppe Palmieri Source Type: journals

A population-based survey on tanning bed use in Germanyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: This analysis indicates that tanning bed use is common in Germany. The positive relationships of appearance and health based motives with tanning bed use are of great concern. The results indicate underlying misconceptions about the positive effect of artificial UV radiation compared to natural UV radiation particular for high-frequency tanners. The data shows the importance as well as the limitations for risk communication in its current effort to inform effectively about the dangers of artificial UV radiation. (Source: BMC Dermatology)
Source: BMC Dermatology - July 19, 2009 Category: Dermatology Authors: Franziska BornerHolger SchutzPeter Wiedemann Source Type: journals

HLA-Cw*0602 associates with a twofold higher prevalence of positive streptococcal throat swab at the onset of psoriasis: a case control studyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Background: The influence of streptococcal infections in the pathogenesis of psoriasis is not yet understood. However, in vitro data suggest that streptococcal factors influence T-cell function in psoriasis in a HLA-dependent manner. However, studies designed to measure the HLA-C/Streptococci interaction are lacking. In the present study, we hypothesized that there is a statistical interaction between the result of streptococcal throat cultures and the presence of the HLA-Cw0602 allele in psoriasis patients. Methods: We performed a case control study using the "Stockholm Psoriasis Cohort" consisting of patients consecutive...
Source: BMC Dermatology - May 29, 2009 Category: Dermatology Authors: Lotus MallbrisKatarina WolkFabio SanchezMona Stahle Source Type: journals

Prevalence and characteristics of aquagenic pruritus in a young African populationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Bathing pruritus is a common finding among young adult Nigerians in the general population. (Source: BMC Dermatology)
Source: BMC Dermatology - April 17, 2009 Category: Dermatology Authors: TA Salami, SO Samuel, KC Eze, E Irekpita, E Oziegbe and MO Momoh Source Type: journals

Prevalence and characteristics of aquagenic pruritus in a young African populationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Bathing pruritus is a common finding among young adult Nigerians in the general population. (Source: BMC Dermatology)
Source: BMC Dermatology - April 17, 2009 Category: Dermatology Authors: T A Salami, S O Samuel, K C Eze, E Irekpita, O E Oziegbe and M O Momoh Source Type: journals

Evaluation of the in vitro skin permeation of antiviral drugs from penciclovir 1% cream and acyclovir 5% cream used to treat herpes simplex virus infectionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Penciclovir 1% cream has the tendency to facilitate the diffusion of the drug through the stratum corneum into the deeper epidermis layers, in which it could reach the target basal cells at effective therapeutical concentration. The small difference in the surface properties between both molecules might also contribute to favour the passage of penciclovir through the epidermis into the deeper basal cells. (Source: BMC Dermatology)
Source: BMC Dermatology - April 2, 2009 Category: Dermatology Authors: Nathalie Hasler-Nguyen, Donald Shelton, Gilbert Ponard, Marlene Bader, Martina Schaffrik and Pascal Mallefet Source Type: journals

Nonlinear modeling of venous leg ulcer healing ratesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: We believe that parameter estimates from a mathematical model may provide a more accurate quantification of wound healing rates, and that similar models should be routinely used to compare the efficacy of various treatments in routine practice and in product registration trials. (Source: BMC Dermatology)
Source: BMC Dermatology - March 31, 2009 Category: Dermatology Authors: Matthew Cardinal, David E Eisenbud, David G. Armstrong, Tania Phillips, Keith Harding and Jonathan Mansbridge Source Type: journals

Mutation analysis of the Gadd45 gene at exon 4 in atypical fibroxanthomaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: These results suggest a possible association between Bax and Gadd45 in AFX, and may refute any possibility of dysfunction of Gadd45 in terms of gene mutation, at least at exon 4 of the Gadd45 gene. (Source: BMC Dermatology)
Source: BMC Dermatology - January 7, 2009 Category: Dermatology Authors: Akio Sakamoto, Shizuka Akieda, Yoshinao Oda, Yukihide Iwamoto and Masazumi Tsuneyoshi Source Type: journals

Dermatitis associated with exposure to a marine cyanobacterium during recreational water exposureemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: During a bloom of L. majuscula there were numerous reports of symptoms that could be attributed to dermotoxins found in L. majuscula. The other four years examined had no L. majuscula blooms and the number of L. majuscula symptoms was much reduced. These cases comprised a high percentage of the cases treated at the first aid station. (Source: BMC Dermatology)
Source: BMC Dermatology - December 30, 2008 Category: Dermatology Authors: Nicholas J Osborne and Glen R Shaw Source Type: journals

Assessment of a new questionnaire for self-reported sun sensitivity in an occupational skin cancer screening programemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: The RTS questionnaire showed a sufficient internal consistency. There is a good convergent validity between the RTS-score and the Fritzpatrick classification avoiding shortcomings of the prevailing standard. The questionnaire represents a simple, reliable and valid instrument for the assessment of sun sensitivity. It can be used in epidemiological studies as well as in skin cancer prevention programs. Further development and standardization of sun sensitivity assessments is necessary to strengthen the evidence of epidemiological studies on causal factors of melanoma and other skin cancers. (Source: BMC Dermatology)
Source: BMC Dermatology - October 24, 2008 Category: Dermatology Authors: Jurgen Tacke, Jens Dietrich, Beatrix Steinebrunner and Antonius Reifferscheid Source Type: journals

Melasma and its association with different types of nevi in women: A case-control studyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Existence of lentigines and melanocytic nevi increases chance of having melasma (Source: BMC Dermatology)
Source: BMC Dermatology - August 5, 2008 Category: Dermatology Authors: Hassan Adalatkhah, Homayoun Sadeghi-bazargani, Nayereh Amini-sani and Somayeh Zeynizadeh Source Type: journals

Melasma and its association with different types of nevi in women: A case control studyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Background: Very little is known about possible association of nevi and melasma. The study objective was to determine if there is an association between melasma and existence of different kinds of nevi. Methods: In a case-control study, 120 female melasma patients referred to dermatology clinic of Ardabil and 120 patients referred to other specialty clinics who lacked melasma were enrolled after matching for age. Number of different types of nevi including lentigines and melanocytic nevi were compared between case and control group patients. Data were entered into the computer and analyzed by SPSS 13 statistical softwar...
Source: BMC Dermatology - August 5, 2008 Category: Dermatology Authors: Hassan Adalatkhah, Homayoun Sadeghi-Bazargani, Nayereh Aminisani and Zeynizade Somayyeh Source Type: journals

A systematic review of natural health product treatment for vitiligoemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Reports investigating the efficacy of NHPs for vitiligo exist, but are of poor methodological quality and contain significant reporting flaws. L-phenylalanine used with phototherapy, and oral Ginkgo biloba as monotherapy show promise and warrant further investigation. (Source: BMC Dermatology)
Source: BMC Dermatology - May 22, 2008 Category: Dermatology Authors: Orest Szczurko and Heather S Boon Source Type: journals

Topical rapamycin inhibits tuberous sclerosis tumor growth in a nude mouse modelemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Topical rapamycin inhibits TSC-related tumor growth. These findings could lead to a novel treatment approach for facial angiofibromas and other TSC skin lesions. (Source: BMC Dermatology)
Source: BMC Dermatology - January 28, 2008 Category: Dermatology Authors: Aubrey Rauktys, Nancy Lee, Laifong Lee and Sandra L Dabora Source Type: journals

The establishment and utility of Sweha-Reg: a Swedish population-based registry to understand hereditary angioedemaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: The present manuscript seeks to raise awareness of the existence of Sweha-Reg to stimulate the international collaboration of registries. A synthesis of data from similar registries across several countries is required to approach an inclusive course understanding of HAE. (Source: BMC Dermatology)
Source: BMC Dermatology - November 30, 2007 Category: Dermatology Authors: Lotus Mallbris, Patrik Nordenfelt, Janne Bjorkander, Anders Lindfors, Sonja Werner and Carl-Fredrik Wahlgren Source Type: journals

Single nucleotide polymorphism-based genome-wide linkage analysis in Japanese atopic dermatitis familiesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: We report the first genome-wide linkage study of atopic dermatitis in an Asian population, and novel loci on chromosomes 15q21 and 1q24 linked to atopic dermatitis. Identification of novel causative genes for atopic dermatitis will advance our understanding of the pathogenesis of atopic dermatitis. (Source: BMC Dermatology)
Source: BMC Dermatology - September 28, 2007 Category: Dermatology Authors: Hisako Enomoto, Emiko Noguchi, Shigeruko Iijima, Takenori Takahashi, Kazuhito Hayakawa, Mikako Ito, Toshiyuki Kano, Takashi Aoki, Yoichi Suzuki, Minori Koga, Mayumi Tamari, Tetsuo Shiohara, Fujio Otsuka and Tadao Arinami Source Type: journals

Self-reported skin morbidity and ethnicity: a population-based study in a Western communityemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: The study showed that there were significant differences in self-reported skin complaints among ethnic groups. Issues concerning the cultural value of some skin symptoms should be examined further. (Source: BMC Dermatology)
Source: BMC Dermatology - June 29, 2007 Category: Dermatology Authors: Florence Dalgard, Jan-Oivind Holm, Ake Svensson, Bernadette Kumar and Johanne Sundby Source Type: journals

Association of toll-interacting protein gene polymorphisms with atopic dermatitisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Variation in the TOLLIP gene may play a role in the pathogenesis of AD. Yet, replication studies in other cohorts and populations are warranted to confirm these association results. (Source: BMC Dermatology)
Source: BMC Dermatology - March 16, 2007 Category: Dermatology News Authors: Tobias T Schimming, Qumar Parwez, Elisabeth Petrasch-Parwez, Michael Nothnagel, Joerg T Epplen and Sabine Hoffjan Source Type: journals

Photostability of commercial sunscreens upon sun exposure and irradiation by ultraviolet lampsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: The present study shows that several sunscreens are photounstable in the UVA range after UVnat and UVart. There is a need for a standardized method to measure photostability and the photostability should be marked on the sunscreen product. (Source: BMC Dermatology)
Source: BMC Dermatology - February 26, 2007 Category: Dermatology News Authors: Helena Gonzalez, Nils Tarras-Wahlberg, Birgitta Stromdahl, Asta Juzeniene, Johan Moan, Olle Larko, Arne Rosen and Ann-Marie Wennberg Source Type: journals

Eruptive papules during efalizumab (anti-CD11a) therapy of psoriasis vulgaris: a case seriesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions. We hypothesize that these papules may represent a unique type of mechanistic inflammatory reaction, seen only in the context of drug-induced CD11a blockade, and not during the natural disease process. (Source: BMC Dermatology)
Source: BMC Dermatology - February 26, 2007 Category: Dermatology News Authors: Michelle A Lowes, Francesca Chamian, Maria V Abello, Craig Leonardi, Wolfgang Dummer, Kim Papp and James G Krueger Source Type: journals

Mohs math, where the error hidesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Our mathematical model identifies key aspects of technique that may contribute to error. To keep the inherent error rate at a minimum, we advocate minimal division and minimal physical thickness of Mohs specimens. (Source: BMC Dermatology)
Source: BMC Dermatology - December 6, 2006 Category: Dermatology News Authors: Jeffrey I Ellis, Tatiana Khrom, Anthony Wong, Mario O Gentile and Daniel M Siegel Source Type: journals

Mohs math – where the error hidesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Our mathematical model identifies key aspects of technique that may contribute to error. To keep the inherent error rate at a minimum, we advocate minimal division and minimal physical thickness of Mohs specimens. (Source: BMC Dermatology)
Source: BMC Dermatology - December 6, 2006 Category: Dermatology News Authors: Jeffrey I Ellis, Tatiana Khrom, Anthony Wong, Mario O Gentile and Daniel M Siegel Source Type: journals

Approaches to discontinuing efalizumab: an open-label study of therapies for managing inflammatory recurrenceemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Inflammatory recurrence after discontinuation of efalizumab therapy is a manageable event, with a number of therapies and approaches available to physicians, including short courses of cyclosporin or methotrexate. (Source: BMC Dermatology)
Source: BMC Dermatology - October 26, 2006 Category: Dermatology News Authors: Kim A Papp, Darryl Toth and Les Rosoph Source Type: journals

Evaluation of efalizumab using safe psoriasis controlemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Efalizumab was shown to have a favorable benefit:risk profile using the comprehensive outcome measure SPC. (Source: BMC Dermatology)
Source: BMC Dermatology - September 19, 2006 Category: Dermatology News Authors: Kim A Papp and Eric Henninger Source Type: journals

Case report and summary of literature: giant perineal keloids treated with post-excisional radiotherapyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Radiotherapy for keloids represents a safe and effective option for post-surgical keloid therapy, especially for patients with bulky or recurrent disease. (Source: BMC Dermatology)
Source: BMC Dermatology - April 19, 2006 Category: Dermatology News Authors: Kristin C Jones, Clifton D Fuller, Join Y Luh, Craig C Childs, Alexander R Miller, Anthony W Tolcher, Terence S Herman and Charles R Thomas Source Type: journals

Cutaneous hypersensitivity reactions to freshwater cyanobacteria – human volunteer studiesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: This preliminary clinical study demonstrates that hypersensitivity reactions to cyanobacteria appear to be infrequent in both the general and dermatological outpatient populations. As cyanobacteria are widely distributed in aquatic environments, a better appreciation of risk factors, particularly with respect to allergic predisposition, may help to refine health advice given to people engaging in recreational activities where nuisance cyanobacteria are a problem. (Source: BMC Dermatology)
Source: BMC Dermatology - April 4, 2006 Category: Dermatology News Authors: Ian Stewart, Ivan M Robertson, Penelope M Webb, Philip J Schluter and Glen R Shaw Source Type: journals

Cutaneous hypersensitivity reactions to freshwater cyanobacteria - human volunteer studiesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: This preliminary clinical study demonstrates that hypersensitivity reactions to cyanobacteria appear to be infrequent in both the general and dermatological outpatient populations. As cyanobacteria are widely distributed in aquatic environments, a better appreciation of risk factors, particularly with respect to allergic predisposition, may help to refine health advice given to people engaging in recreational activities where nuisance cyanobacteria are a problem. (Source: BMC Dermatology)
Source: BMC Dermatology - April 4, 2006 Category: Dermatology News Authors: Ian Stewart, Ivan M Robertson, Penelope M Webb, Philip J Schluter and Glen R Shaw Source Type: journals

Primary irritant and delayed-contact hypersensitivity reactions to the freshwater cyanobacterium Cylindrospermopsis raciborskii and its associated toxin cylindrospermopsinemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: The irritant properties and cutaneous sensitising potential of cylindrospermopsin indicate that these toxicological endpoints should be considered by public health advisors and reservoir managers when setting guidelines for recreational exposure to cyanobacteria. (Source: BMC Dermatology)
Source: BMC Dermatology - March 31, 2006 Category: Dermatology News Authors: Ian Stewart, Alan A Seawright, Philip J Schluter and Glen R Shaw Source Type: journals

Primary irritant and delayed-contact hypersensitivity reactions to the freshwater cyanobacterium Cylindrospermopsis raciborskiiand its associated toxin cylindrospermopsinemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: The irritant properties and cutaneous sensitising potential of cylindrospermopsin indicate that these toxicological endpoints should be considered by public health advisors and reservoir managers when setting guidelines for recreational exposure to cyanobacteria. (Source: BMC Dermatology)
Source: BMC Dermatology - March 31, 2006 Category: Dermatology News Authors: Ian Stewart, Alan A Seawright, Philip J Schluter and Glen R Shaw Source Type: journals

Increasing incidence of skin disorders in children? A comparison between 1987 and 2001email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: The overall incidence rate of all skin diseases combined in general practice decreased whereas the incidence rates of bacterial, mycotic and atopic skin diseases increased. (Source: BMC Dermatology)
Source: BMC Dermatology - March 21, 2006 Category: Dermatology News Authors: Robbert SA Mohammedamin, Johannes C van der Wouden, Sander Koning, Michiel W van der Linden, François G Schellevis, Lisette WA van Suijlekom-Smit and Bart W Koes Source Type: journals

Anti-thyroid peroxidase antibody and vitiligo: a controlled studyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: According to our study, anti-TPO was shown to be significantly more common in vitiligo patients especially in young women, compared with control group. As this antibody is a relatively sensitive and specific marker of autoimmune thyroid disorders including Hashimoto thyroiditis and Graves' disease, and considering the fact that vitiligo usually precedes the onset of thyroid dysfunction, periodic follow-up of vitiligo patients for detecting thyroid diseases is further emphasized especially in young women with increased level of anti-TPO. (Source: BMC Dermatology)
Source: BMC Dermatology - March 10, 2006 Category: Dermatology News Authors: Maryam Daneshpazhooh, Mahtab Mostofizadeh G , Javad Behjati, Maryam Akhyani and Reza Mahmoud Robati Source Type: journals

Death from colonic disease in epidermolysis bullosa dystrophicaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Constipation is a common clinical feature of RDEB, but fetal complications of chronic constipation are rarely reported. To the author's best knowledge, it has not been reported or recognized in the English literature previously. The aggressive assessment of constipation with fecal impaction is recommended in patients with RDEB. (Source: BMC Dermatology)
Source: BMC Dermatology - February 15, 2006 Category: Dermatology News Authors: Chih-Hsin Hsieh, Che-Jen Huang and Gau-Tyan Lin Source Type: journals

Regular use of a hand cream can attenuate skin dryness and roughness caused by frequent hand washingemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Repetitive and frequent hand washing increases skin dryness and roughness. Use of a hand cream immediately after each hand wash can confine both skin dryness and skin roughness. Regular use of skin care preparations should therefore help to prevent both dry and rough skin among healthcare workers in clinical practice. (Source: BMC Dermatology)
Source: BMC Dermatology - February 13, 2006 Category: Dermatology News Authors: Günter Kampf and Joachim Ennen Source Type: journals

Impact of efalizumab on patient-reported outcomes in high-need psoriasis patients: results of the international, randomized, placebo-controlled Phase III Clinical Experience Acquired with Raptiva (CLEAR) trial [NCT00256139]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: A 12-week course of efalizumab improved HRQOL and other patient-reported outcomes in patients with moderate to severe plaque psoriasis. The benefits of efalizumab therapy in High-Need patients were similar to those observed in the total study population, indicating that the beneficial impact of efalizumab on QOL is consistent regardless of disease severity, prior therapy, or contraindications to previous therapies. (Source: BMC Dermatology)
Source: BMC Dermatology - December 16, 2005 Category: Dermatology News Authors: Jean-Paul Ortonne, Neil Shear, Stephen Shumack, Eric Henninger and the CLEAR Multinational Study Group Source Type: journals

A liver fibrosis cocktail? Psoriasis, methotrexate and genetic hemochromatosisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: We conclude that methotrexate therapy is relatively safe in patients with genetic hemochromatosis, with no other risk factor, but caution that the risk of fibrosis be monitored, preferably by non-invasive techniques, or by liver biopsy. (Source: BMC Dermatology)
Source: BMC Dermatology - November 29, 2005 Category: Dermatology News Authors: Joseph Mathew, May Y Leong, Nick Morley and Alastair D Burt Source Type: journals

Evaluation of the profile of alopecia areata and the prevalence of thyroid function test abnormalities and serum autoantibodies in Iranian patientsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: The incidence of positive auto-immune antibodies in Iranian patients is higher than previous reports. Concerning the female:male ratio, thyroid function tests and the prevalence of alopecia in first-degree relatives, our results are compatible with previous data obtained from different ethnic populations. Previous reports documented that a greater severity and longer duration of AA were seen in the early onset forms; however our result are relatively different which could be explained by differences in genetic factors. (Source: BMC Dermatology)
Source: BMC Dermatology - October 31, 2005 Category: Dermatology News Authors: Hassan Seyrafi, Maryam Akhiani, Hamed Abbasi, Sahar Mirpour and Ali Gholamrezanezhad Source Type: journals