Transcriptomic data reveals the dynamics of terpenoids biosynthetic pathway of fenugreek
Medicinal plants are rich sources for treating various diseases due their bioactive secondary metabolites. Fenugreek (Trigonella foenum-graecum) is one of the medicinal plants traditionally used in human nutritio... (Source: BMC Genomics)
Source: BMC Genomics - April 22, 2024 Category: Genetics & Stem Cells Authors: Sara Lamei Javan, Arman Beyraghdar Kashkooli, AbdolAli Shojaeiyan and Sina Majidian Tags: Research Source Type: research

Genetic and phenotypic analysis of 225 Chinese children with developmental delay and/or intellectual disability using whole-exome sequencing
Developmental delay (DD), or intellectual disability (ID) is a very large group of early onset disorders that affects 1 –2% of children worldwide, which have diverse genetic causes that should be identified. Ge... (Source: BMC Genomics)
Source: BMC Genomics - April 22, 2024 Category: Genetics & Stem Cells Authors: Heqian Ma, Lina Zhu, Xiao Yang, Meng Ao, Shunxiang Zhang, Meizhen Guo, Xuelin Dai, Xiuwei Ma and Xiaoying Zhang Tags: Research Source Type: research

Key mRNAs and lncRNAs of pituitary that affect the reproduction of FecB  + + small tail han sheep
The pituitary directly regulates the reproductive process through follicle-stimulating hormone (FSH) and luteinizing hormone (LH). Transcriptomic research on the pituitaries of ewes with different FecB (fecundity... (Source: BMC Genomics)
Source: BMC Genomics - April 22, 2024 Category: Genetics & Stem Cells Authors: Jianqi Yang, Jishun Tang, Xiaoyun He, Ran Di, Xiaosheng Zhang, Jinlong Zhang, Xiaofei Guo, Wenping Hu and Mingxing Chu Tags: Research Source Type: research

scGAL: unmask tumor clonal substructure by jointly analyzing independent single-cell copy number and scRNA-seq data
Accurately deciphering clonal copy number substructure can provide insights into the evolutionary mechanism of cancer, and clustering single-cell copy number profiles has become an effective means to unmask in... (Source: BMC Genomics)
Source: BMC Genomics - April 22, 2024 Category: Genetics & Stem Cells Authors: Ruixiang Li, Fangyuan Shi, Lijuan Song and Zhenhua Yu Tags: Research Source Type: research

Multiple transcriptome analyses reveal mouse testis developmental dynamics
The testes are the organs of gamete production and testosterone synthesis. Up to date, no model system is available for mammalian testicular development, and only few studies have characterized the mouse testi... (Source: BMC Genomics)
Source: BMC Genomics - April 22, 2024 Category: Genetics & Stem Cells Authors: Anqi Chen, Chaoneng Ji, Chengtao Li, Beate Brand-Saberi and Suhua Zhang Tags: Research Source Type: research

GenoMycAnalyzer: a web-based tool for species and drug resistance prediction for Mycobacterium genomes
Drug-resistant tuberculosis (TB) is a major threat to global public health. Whole-genome sequencing (WGS) is a useful tool for species identification and drug resistance prediction, and many clinical laborator... (Source: BMC Genomics)
Source: BMC Genomics - April 20, 2024 Category: Genetics & Stem Cells Authors: Doyoung Kim, Jeong-Ih Shin, In Young Yoo, Sungjin Jo, Jiyon Chu, Woo Young Cho, Seung-Hun Shin, Yeun-Jun Chung, Yeon-Joon Park and Seung-Hyun Jung Tags: Software Source Type: research

Genome-wide identification, characterization and expression of C2H2 zinc finger gene family in Opisthopappus species under salt stress
The C2H2 zinc finger protein family plays important roles in plants. However, precisely how C2H2s function in Opisthopappus (Opisthopappus taihangensis and Opisthopappus longilobus) remains unclear. (Source: BMC Genomics)
Source: BMC Genomics - April 19, 2024 Category: Genetics & Stem Cells Authors: Xiaojuan Zhou, Ting Gao, Yimeng Zhang, Mian Han, Yuexin Shen, Yu Su, Xiaolong Feng, Qi Wu, Genlou Sun and Yiling Wang Tags: Research Source Type: research

GbyE: an integrated tool for genome widely association study and genome selection based on genetic by environmental interaction
The growth and development of organism were dependent on the effect of genetic, environment, and their interaction. In recent decades, lots of candidate additive genetic markers and genes had been detected by ... (Source: BMC Genomics)
Source: BMC Genomics - April 19, 2024 Category: Genetics & Stem Cells Authors: Xinrui Liu, Mingxiu Wang, Jie Qin, Yaxin Liu, Shikai Wang, Shiyu Wu, Ming Zhang, Jincheng Zhong and Jiabo Wang Tags: Research Source Type: research

Sequence characteristics, genetic diversity and phylogenetic analysis of the Cucurbita ficifolia (Cucurbitaceae) chloroplasts genome
Curcubita ficifolia Bouch é (Cucurbitaceae) has high value as a food crop and medicinal plant, and also has horticultural value as rootstock for other melon species. China is home to many different cultivars, but ... (Source: BMC Genomics)
Source: BMC Genomics - April 18, 2024 Category: Genetics & Stem Cells Authors: Shuilian He, Bin Xu, Siyun Chen, Gengyun Li, Jie Zhang, Junqiang Xu, Hang Wu, Xuejiao Li and Zhengan Yang Tags: Research Source Type: research

Genome-wide identification and expression pattern analysis of the Aux/IAA (auxin/indole-3-acetic acid) gene family in alfalfa (Medicago sativa) and the potential functions under drought stress
Auxin/induced-3-acetic acid (Aux/IAA) is an important plant hormone that affects plant growth and resistance to abiotic stresses. Drought stress is a vital factor in reducing plant biomass yield and production... (Source: BMC Genomics)
Source: BMC Genomics - April 18, 2024 Category: Genetics & Stem Cells Authors: Jinqing Zhang, Shuxia Li, Xueqin Gao, Yaling Liu and BingZhe Fu Tags: Research Source Type: research

Screening of temperature-responsive signalling molecules during sex differentiation in Asian yellow pond turtle (Mauremys mutica)
The Asian yellow pond turtle (Mauremys mutica) is an important commercial freshwater aquaculture species in China. This species is a highly sexually dimorphic species, with males growing at a faster rate than fem... (Source: BMC Genomics)
Source: BMC Genomics - April 18, 2024 Category: Genetics & Stem Cells Authors: Xiaoli Liu, Haoyang Xu, Mingwei Peng, Chenyao Zhou, Chengqing Wei, Xiaoyou Hong, Wei Li, Chen Chen, Liqin Ji and Xinping Zhu Tags: Research Source Type: research

Multi-trait GWAS for diverse ancestries: mapping the knowledge gap
Approximately 95% of samples analyzed in univariate genome-wide association studies (GWAS) are of European ancestry. This bias toward European ancestry populations in association screening also exists for othe... (Source: BMC Genomics)
Source: BMC Genomics - April 17, 2024 Category: Genetics & Stem Cells Authors: Lucie Troubat, Deniz Fettahoglu, L éo Henches, Hugues Aschard and Hanna Julienne Tags: Research Source Type: research

Prominent transcriptomic changes in Mycobacterium intracellulare under acidic and oxidative stress
Mycobacterium avium complex (MAC), including Mycobacterium intracellulare is a member of slow-growing mycobacteria and contributes to a substantial proportion of nontuberculous mycobacterial lung disease in human... (Source: BMC Genomics)
Source: BMC Genomics - April 17, 2024 Category: Genetics & Stem Cells Authors: Hyun-Eui Park, Kyu-Min Kim, Jeong-Ih Shin, Jeong-Gyu Choi, Won-Jun An, Minh Phuong Trinh, Kyeong-Min Kang, Jung-Wan Yoo, Jung-Hyun Byun, Myung Hwan Jung, Kon-Ho Lee, Hyung-Lyun Kang, Seung Cheol Baik, Woo-Kon Lee and Min-Kyoung Shin Tags: Research Source Type: research

Tissue-specific atlas of trans-models for gene regulation elucidates complex regulation patterns
Deciphering gene regulation is essential for understanding the underlying mechanisms of healthy and disease states. While the regulatory networks formed by transcription factors (TFs) and their target genes ha... (Source: BMC Genomics)
Source: BMC Genomics - April 17, 2024 Category: Genetics & Stem Cells Authors: Robert Dagostino and Assaf Gottlieb Tags: Research Source Type: research

Comprehensive genomic analysis of the SARS-CoV-2 Omicron variant BA.2.76 in Jining City, China, 2022
This study aims to analyze the molecular characteristics of the novel coronavirus (SARS-CoV-2) Omicron variant BA.2.76 in Jining City, China. (Source: BMC Genomics)
Source: BMC Genomics - April 17, 2024 Category: Genetics & Stem Cells Authors: Qiang Yin, Wei Liu, Yajuan Jiang, Qiang Feng, Xiaoyu Wang, Huixin Dou, Zanzan Liu, Feifei He, Yingying Fan, Baihai Jiao and Boyan Jiao Tags: Research Source Type: research