Helminth-derived proteins as immune system regulators: a systematic review of their promise in alleviating colitis
Helminth-derived proteins have immunomodulatory properties, influencing the host ’s immune response as an adaptive strategy for helminth survival. Helminth-derived proteins modulate the immune response by induc... (Source: BMC Immunology)
Source: BMC Immunology - April 18, 2024 Category: Allergy & Immunology Authors: Maimonah Alghanmi, Faisal Minshawi, Tarfa A. Altorki, Ayat Zawawi, Isra Alsaady, Abdallah Y Naser, Hassan Alwafi, Soa ’ad M. Alsulami, Ala A. Azhari, Anwar M Hashem and Rowa Alhabbab Tags: Research Source Type: research
Association of interleukin-17A and chemokine/vascular endothelial growth factor-induced angiogenesis in newly diagnosed patients with bladder cancer
The human interleukin-17 (IL-17) family comprises IL-17A to IL-17 F; their receptors are IL-17RA to IL-17RE. Evidence revealed that these cytokines can have a tumor-supportive or anti-tumor impact on human mal... (Source: BMC Immunology)
Source: BMC Immunology - March 21, 2024 Category: Allergy & Immunology Authors: Ali Moadab, Mohammad Rafie Valizadeh, Alireza Nazari and Hossein Khorramdelazad Tags: Research Source Type: research
Causal relationship between immune cells and telomere length: mendelian randomization analysis
The causal relationship between immune cells and telomere length remains controversial. (Source: BMC Immunology)
Source: BMC Immunology - March 8, 2024 Category: Allergy & Immunology Authors: Yujian Li, Shenglin Lai and Xuan Kan Tags: Research Source Type: research
Subcutaneous immunoglobulin replacement therapy in patients with immunodeficiencies – impact of drug packaging and administration method on patient reported outcomes
Here, the perspective of patients with primary and secondary immunodeficiency receiving subcutaneous immunoglobulin (SCIg) via introductory smaller size pre-filled syringes (PFS) or vials were compared. (Source: BMC Immunology)
Source: BMC Immunology - February 20, 2024 Category: Allergy & Immunology Authors: R. Mallick, G. Solomon, P. Bassett, X. Zhang, P. Patel and O. Lepeshkina Tags: Research Source Type: research
Network pharmacology-based strategy to investigate the mechanisms of artemisinin in treating primary Sj ögren’s syndrome
The study aimed to explore the mechanism of artemisinin in treating primary Sj ögren’s syndrome (pSS) based on network pharmacology and experimental validation. (Source: BMC Immunology)
Source: BMC Immunology - February 12, 2024 Category: Allergy & Immunology Authors: Jia-he Liao, Qian He, Zi-wei Huang, Xin-bo Yu, Jian-ying Yang, Yan Zhang, Wei-jiang Song, Jing Luo and Qing-wen Tao Tags: Research Source Type: research
Dendritic cells under allergic condition enhance the activation of pruritogen-responsive neurons via inducing itch receptors in a co-culture study
Itch sensitization has been reported in patients with chronic allergic skin diseases and observed in a mouse model of allergic contact dermatitis (ACD). There is evidence suggesting that neuroimmune interactio... (Source: BMC Immunology)
Source: BMC Immunology - February 12, 2024 Category: Allergy & Immunology Authors: Tichakorn Singto, Viviane Filor, Jonathan Vidak, Robert Klopfleisch and Wolfgang B äumer Tags: Research Source Type: research
Immune responses to P falciparum antibodies in symptomatic malaria patients with variant hemoglobin genotypes in Ghana
Haemoglobin (Hb) variants such as sickle cell trait (SCT/HbAS) play a role in protecting against clinical malaria, but little is known about the development of immune responses against malaria parasite (Plasmodiu... (Source: BMC Immunology)
Source: BMC Immunology - February 9, 2024 Category: Allergy & Immunology Authors: Kwame Kumi Asare, Benjamin Agrah, Fiifi Solomon Ofori-Acquah, William Kudzi, Nii Ayite Aryee and Linda Eva Amoah Tags: Research Source Type: research
Hyperactivation and enhanced cytotoxicity of reduced CD8+ gamma delta T cells in the intestine of patients with Crohn ’s disease correlates with disease activity
We aimed to investigate the immune characteristics of intestinal CD8+ gamma delta T (CD8+ γδ T) cells in Crohn’s disease (CD) and their correlation with disease activity. (Source: BMC Immunology)
Source: BMC Immunology - February 9, 2024 Category: Allergy & Immunology Authors: Tao Zhu, Linlin Zhu, Caixia Sheng, Danju Wu, Qianru Gu, Zhinong Jiang, Jiaqi Xu, Guoxiang Fu and Yujie Jiang Tags: Research Source Type: research
Systematic evaluation of B-cell clonal family inference approaches
The reconstruction of clonal families (CFs) in B-cell receptor (BCR) repertoire analysis is a crucial step to understand the adaptive immune system and how it responds to antigens. The BCR repertoire of an ind... (Source: BMC Immunology)
Source: BMC Immunology - February 8, 2024 Category: Allergy & Immunology Authors: Daria Balashova, Barbera D. C. van Schaik, Maria Stratigopoulou, Jeroen E. J. Guikema, Tom G. Caniels, Mathieu Claireaux, Marit J. van Gils, Anne Musters, Dornatien C. Anang, Niek de Vries, Victor Greiff and Antoine H. C. van Kampen Tags: Research Source Type: research
Expression of the immune checkpoint molecules CD226 and TIGIT in preeclampsia patients
Imbalanced immune responses are involved in developing preeclampsia (PE). We wish to explore the expression and potential changes of immune checkpoint molecules TIGIT, CD226 and CD155 in PE patients. (Source: BMC Immunology)
Source: BMC Immunology - February 7, 2024 Category: Allergy & Immunology Authors: Cui Li, Haiyan Liu and Zhongliang Duan Tags: Research Source Type: research
Oral administration of DNA alginate nanovaccine induced immune-protection against Helicobacter pylori in Balb/C mice
Helicobacter pylori (H. Pylori), is an established causative factor for the development of gastric cancer and the induction of persistent stomach infections that may lead to peptic ulcers. In recent decades, s... (Source: BMC Immunology)
Source: BMC Immunology - February 3, 2024 Category: Allergy & Immunology Authors: Arezo Kaveh-Samani, Samaneh Dalali, Fatemeh Kaviani, Tohid Piri-Gharaghie and Abbas Doosti Tags: Research Source Type: research
Profiling of T cell repertoire in peripheral blood of patients from type 2 diabetes with complication
More than 90% of patients with diabetes worldwide are type 2 diabetes (T2D), which is caused by insulin resistance or impaired producing insulin by pancreatic β cells. T2D and its complications, mainly large c... (Source: BMC Immunology)
Source: BMC Immunology - January 31, 2024 Category: Allergy & Immunology Authors: YongHui Yin, YingLi Sheng, Shuo Gao, JinTao Zhang, WenKuan Wang, YingJun Liu, TingTing Xu and Yi Zhang Tags: Research Source Type: research
Tumor microenvironment and immune system preservation in early-stage breast cancer: routes for early recurrence after mastectomy and treatment for lobular and ductal forms of disease
Intra-ductal cancer (IDC) is the most common type of breast cancer, with intra-lobular cancer (ILC) coming in second. Surgery is the primary treatment for early stage breast cancer. There are now irrefutable d... (Source: BMC Immunology)
Source: BMC Immunology - January 25, 2024 Category: Allergy & Immunology Authors: Hassan A. Saad, Azza Baz, Mohamed Riad, Mohamed E. Eraky, Ahmed El-Taher, Mohamed I. Farid, Khaled Sharaf, Huda E. M. Said and Lotfy A. Ibrahim Tags: Research Source Type: research
Predictive biomarkers for immune-related adverse events in cancer patients treated with immune-checkpoint inhibitors
The objective of this study was to identify potential predictors of immune-related adverse events (irAEs) in cancer patients receiving immune checkpoint inhibitor therapy among serum indexes, case data, and li... (Source: BMC Immunology)
Source: BMC Immunology - January 24, 2024 Category: Allergy & Immunology Authors: Jingting Wang, Yan Ma, Haishan Lin, Jing Wang and Bangwei Cao Tags: Research Source Type: research
Negative prognostic behaviour of PD-L1 expression in tongue and larynx squamous cell carcinoma and its significant predictive power in combination with PD-1 expression on TILs
Biomarkers that can predict outcome will improve the efficacy of treatment for HNSCC patients. In this regard, we retrospectively evaluated the prognostic effect of PD1, PD-L1, and CD45RO in tongue and larynx ... (Source: BMC Immunology)
Source: BMC Immunology - January 16, 2024 Category: Allergy & Immunology Authors: Simin Ahmadvand, Lotf-Ali Norouzi, Yousef Mohammadi, Akbar Safaei, Bijan Khademi, Maziar Motiee-Langroudi and Abbas Ghaderi Tags: Research Source Type: research
