Histological reappraisal of IgA nephropathy: the role of glomerular pattern of injury and mesangial complement deposition
There is a clear need to refine the histological assessment in IgA Nephropathy (IgAN). We sought to investigate the clinical significance of the light microscopy (LM) pattern of glomerular injury and of the in... (Source: BMC Nephrology)
Source: BMC Nephrology - April 24, 2024 Category: Urology & Nephrology Authors: Bogdan Obri șcă, Valentin Mocanu, Roxana Jurubiță, Alexandra Vrabie, Andreea Berechet, Ștefan Lujinschi, Bogdan Sorohan, Andreea Andronesi, Camelia Achim, Gabriela Lupușoru, Georgia Micu, Nicu Caceaune, Mihaela Gherghiceanu and Gener Ismail Tags: Research Source Type: research

Pediatric frequent relapsing nephrotic syndrome with multiple cerebral infarctions accompanied by patent foramen ovale and cerebral venous sinus thrombosis: a case report
Idiopathic nephrotic syndrome (NS) presents as a hypercoagulable state, of which thromboembolism (TE) is a well-known life-threatening complication. Although TE is more likely to occur in venous vessels than a... (Source: BMC Nephrology)
Source: BMC Nephrology - April 24, 2024 Category: Urology & Nephrology Authors: Zentaro Kiuchi, Eriko Tanaka, Saaya Nunokawa, Sawako Yoshida, Akira Hosaki, Tomohito Kogure and Masami Narita Tags: Case Report Source Type: research

The clinical utility of cystatin C based eGFR in assessing renal function among HIV/AIDs patients on ART at Mildmay Uganda
In clinical practice, Measurement of estimated glomerular filtration rates (eGFR) is the gold standard assessing renal function the glomerular filtration rate often estimated from plasma creatinine. Several st... (Source: BMC Nephrology)
Source: BMC Nephrology - April 23, 2024 Category: Urology & Nephrology Authors: Enock Wekiya, Godfrey P. Mujuzi, Jane Nakiyingi, Juliet Sanya, Moses Matovu, Ocung Guido, Jane Nakaweesi, Charles Karamagi, Joan K. Nakayaga, Edrisa I. Mutebi and Damalie Nakanjako Tags: Research Source Type: research

A loss-of-function AGTR1 variant in a critically-ill infant with renal tubular dysgenesis: case presentation and literature review
Renal tubular dysgenesis (RTD) is a severe disorder with poor prognosis significantly impacting the proximal tubules of the kidney while maintaining an anatomically normal gross structure. The genetic origin o... (Source: BMC Nephrology)
Source: BMC Nephrology - April 22, 2024 Category: Urology & Nephrology Authors: Aljazi Al-Maraghi, Waleed Aamer, Mubarak Ziab, Elbay Aliyev, Najwa Elbashir, Sura Hussein, Sasirekha Palaniswamy, Dhullipala Anand, Donald R. Love, Adrian Charles, Ammira A.S.Akil and Khalid A. Fakhro Tags: Case Report Source Type: research

Contrast-induced acute kidney injury: a review of definition, pathogenesis, risk factors, prevention and treatment
Contrast-induced acute kidney injury (CI-AKI) has become the third leading cause of hospital-acquired AKI, which seriously threatens the health of patients. To date, the precise pathogenesis of CI-AKI has rema... (Source: BMC Nephrology)
Source: BMC Nephrology - April 22, 2024 Category: Urology & Nephrology Authors: Yanyan Li and Junda Wang Tags: Review Source Type: research

Trajectories of atherosclerotic cardiovascular disease risk scores as a predictor for incident chronic kidney disease
The relationship between atherosclerosis and renal function is well established. Atherosclerotic cardiovascular disease (ASCVD) risk scores reflect atherosclerotic burden, which changes over time. We investiga... (Source: BMC Nephrology)
Source: BMC Nephrology - April 22, 2024 Category: Urology & Nephrology Authors: Hye Sun Lee, Hong Il Lim, Tae Ju Moon, So Young Lee and Jun-Hyuk Lee Tags: Research Source Type: research

Clinical significance of urinary inflammatory biomarkers in patients with IgA nephropathy
IgA nephropathy (IgAN) is the most common type of primary glomerulonephritis, although the definitive markers are unknown. We aimed to investigate the clinical significance of urinary cytokines in patients wit... (Source: BMC Nephrology)
Source: BMC Nephrology - April 22, 2024 Category: Urology & Nephrology Authors: Soo-Young Yoon, Jin Sug Kim, Su Woong Jung, Yang Gyun Kim, Ju-Young Moon, Sang-Ho Lee, Sung-Vin Yim, Hyeon Seok Hwang and Kyunghwan Jeong Tags: Research Source Type: research

Single-cell transcriptome atlas in C57BL/6 mice encodes morphological phenotypes in the aging kidneys
C57BL/6 mice are frequently utilized as murine models with the desired genetic background for altertion in multiple research contexts. So far, there is still a lack of comprehensive kidney morphology and singl... (Source: BMC Nephrology)
Source: BMC Nephrology - April 19, 2024 Category: Urology & Nephrology Authors: Shanzhi Yang, Peimin Liu, Yan Zhang, Haosen Xu, Jinyi Lan, Huan Jiang, Guoxiang Jin and Xiaoyan Bai Tags: Research Source Type: research

Development and validation of a novel nomogram model for predicting delayed graft function in deceased donor kidney transplantation based on pre-transplant biopsies
Delayed graft function (DGF) is an important complication after kidney transplantation surgery. The present study aimed to develop and validate a nomogram for preoperative prediction of DGF on the basis of cli... (Source: BMC Nephrology)
Source: BMC Nephrology - April 19, 2024 Category: Urology & Nephrology Authors: Meihe Li, Xiaojun Hu, Yang Li, Guozhen Chen, Chen-guang Ding, Xiaohui Tian, Puxun Tian, Heli Xiang, Xiaoming Pan, Xiaoming Ding, Wujun Xue, Jin Zheng and Chenguang Ding Tags: Research Source Type: research

Review on epidemiology, disease burden, and treatment patterns of IgA nephropathy in select APAC countries
Immunoglobulin type A (IgA) nephropathy is the most common primary glomerulonephritis (GN) worldwide with higher rates in East and Pacific Asia compared to North America and Europe. Despite high reported preva... (Source: BMC Nephrology)
Source: BMC Nephrology - April 16, 2024 Category: Urology & Nephrology Authors: Omer Zaidi, Fen Du, Zhaoli Tang, Sandipan Bhattacharjee and Kristin Pareja Tags: Review Source Type: research

Atypical anti-glomerular basement membrane disease with membranous hyperplasia: diagnostic challenges and treatment variability
This case report presents a detailed analysis of a 31-year-old male patient who presented with a complex array of clinical symptoms, including proteinuria, hematuria, edema, and kidney insufficiency. Despite u... (Source: BMC Nephrology)
Source: BMC Nephrology - April 15, 2024 Category: Urology & Nephrology Authors: Ruoyu Tong, Zhengmao Luo, Xianyang Zhong, Liming Fan, Huangwen Lai, Meng Shen and Yuanhang Huang Tags: Case Report Source Type: research

Determinants of early chronic kidney disease in patients with recently diagnosed type 2 diabetes mellitus: a retrospective study from the Taiwan Diabetes Registry
We tried to identify the risk factor associate with early chronic kidney disease (CKD) in recently diagnosed type 2 diabetes mellitus patients by utilizing real-world data from Taiwan Diabetes Registry. (Source: BMC Nephrology)
Source: BMC Nephrology - April 15, 2024 Category: Urology & Nephrology Authors: Yun-Kai Yeh, Kuan-Hung Lin, Wayne Huey-Herng Sheu, Su-Huey Lo, Yen-Po Yeh, Chien-Ning Huang, Chii-Min Hwu and Chieh-Hsiang Lu Tags: Research Source Type: research

Increased risk of hypocalcemia with decreased kidney function in patients prescribed bisphosphonates based on real-world data from the MID-NET ® in Japan: a new-user cohort study
In the post-marketing stage, cases of hypocalcemia associated with bisphosphonate preparations (BPs) have been reported in patients with decreased kidney function, despite warning against use of BPs in such pa... (Source: BMC Nephrology)
Source: BMC Nephrology - April 15, 2024 Category: Urology & Nephrology Authors: Tomoaki Hasegawa, Maki Komamine, Chieko Ishiguro, Haruka Motomura, Kazuhiro Kajiyama, Takahiro Nonaka, Yuki Nakazato, Ryota Kimura, Harumi Maniwa, Toyotaka Iguchi, Naoya Horiuchi and Yoshiaki Uyama Tags: Research Source Type: research

The prevalence of accessory renal arteries in sudanese population in Khartoum State: a cross-sectional CT study from 2017 to 2020
This study aimed ... (Source: BMC Nephrology)
Source: BMC Nephrology - April 15, 2024 Category: Urology & Nephrology Authors: Safaa. Mohammed, Eltayeb. AbdAlla, Amal. Elhag and Abdelmoniem. El-Mardi Tags: Research Source Type: research

The mediating role of hope in the relation between uncertainty and social support with self-management among patients with ESKD undergoing hemodialysis
This study aimed to test the relationship between social support, uncertainty and self-management among HD pati... (Source: BMC Nephrology)
Source: BMC Nephrology - April 12, 2024 Category: Urology & Nephrology Authors: Ali Mohammad Parviniannasab, Fatemeh Dehghani and Seyyed Ali Hosseini Tags: Research Source Type: research