Biological Psychiatry
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Manuscript Submission Form—Biological Psychiatry
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Section 1: Instructions. A copy of this form, with signatures included from ALL authors on the manuscript, must accompany every new manuscript submission before it will be considered for publication. Please fully complete to eliminate delays in submission. Use an additional form if there are more than 10 authors. Please scan this completed form and attach it electronically during the submission process. If you are unable to do so, fax the completed form to the Editorial Office at (214) 648-0881. (Source: Biological Psychiatry)
Source: Biological Psychiatry - November 9, 2009 Category: Psychiatry Tags: Frontmatter Source Type: journals
Guide for Authors
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Biological Psychiatry is the official journal of the Society of Biological Psychiatry. The Journal rapidly publishes reports of novel results on a broad range of topics related to the pathophysiology and treatment of major neuropsychiatric disorders. Both basic and clinical neuroscience contributions are encouraged, particularly those addressing genetic and environmental risk factors, neural circuitry and neurochemistry, and important new therapeutic approaches. (Source: Biological Psychiatry)
Source: Biological Psychiatry - November 9, 2009 Category: Psychiatry Tags: Frontmatter Source Type: journals
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(Source: Biological Psychiatry)
Source: Biological Psychiatry - November 9, 2009 Category: Psychiatry Tags: Frontmatter Source Type: journals
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Biological Psychiatry (ISSN 0006-3223) is published semimonthly by Elsevier Inc., 360 Park Avenue South, New York, NY 10010-1710. Periodicals postage paid at New York, NY and additional mailing offices. (Source: Biological Psychiatry)
Source: Biological Psychiatry - November 9, 2009 Category: Psychiatry Tags: Frontmatter Source Type: journals
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Source: Biological Psychiatry - November 9, 2009 Category: Psychiatry Tags: Frontmatter Source Type: journals
In Memory of Elizabeth Young
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Dr. Elizabeth Young, Professor of Psychiatry and Senior Research Professor at the Molecular and Behavioral Neuroscience Institute (MBNI) and member of the Depression Center at the University of Michigan passed away on September 1, 2009 after a yearlong battle with leukemia. She was 59 years old. (Source: Biological Psychiatry)
Source: Biological Psychiatry - November 9, 2009 Category: Psychiatry Authors: Huda Akil, Stanley J. Watson, Gregory W. Dalack, John F. Greden, Jon-Kar Zubieta Tags: Correspondence Source Type: journals
The following Biological Psychiatry articles in press are now available in full text at http://www.sobp.org/journal
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Our goal is to rapidly disseminate information to our readers. Pre-publication abstracts of accepted articles are posted on our website weekly, and upon availability of a corrected proof, full articles are immediately posted and citable. Articles posted since the last issue are listed below. Interested readers are encouraged to contact authors directly for information prior to publication and to read the associated article in its entirety upon publication. (Source: Biological Psychiatry)
Source: Biological Psychiatry - November 9, 2009 Category: Psychiatry Tags: On the Internet Source Type: journals
Endophenotypes: Bridging Genomic Complexity and Disorder Heterogeneity
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As will be familiar to most readers of this journal, endophenotypes are relatively well-specified physiological or behavioral measures that are considered to occupy the terrain between disease symptoms and risk genotypes. The endophenotype concept has been an enduring feature in psychiatry for nearly 40 years, since its introduction in the classic monograph by Gottesman and Shields (). However, endophenotypes have enjoyed accelerating popularity in recent years due to their potential associations with genomic data to provide a way forward for parsing complex, heterogeneous disease phenotypes such as schizophrenia. Several ...
Source: Biological Psychiatry - November 9, 2009 Category: Psychiatry Authors: Thomas R. Insel, Bruce N. Cuthbert Tags: Commentary Source Type: journals
A brief summary of the articles appearing in this issue of Biological Psychiatry
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In this review, Tam et al. (pages 1005–1012) discuss the recent progress in the detection and interpretation of copy number variations in schizophrenia. These previously unknown deletions and duplications in the genome of schizophrenia patients have begun to provide insight into the underlying susceptibility genetic factors, biological pathways and genetic architecture related to schizophrenia, and may continue to reveal information about other psychiatric disorders. (Source: Biological Psychiatry)
Source: Biological Psychiatry - November 9, 2009 Category: Psychiatry Source Type: journals
Manuscript Submission Form—Biological Psychiatry
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Section 1: Instructions. A copy of this form, with signatures included from ALL authors on the manuscript, must accompany every new manuscript submission before it will be considered for publication. Please fully complete to eliminate delays in submission. Use an additional form if there are more than 10 authors. Please scan this completed form and attach it electronically during the submission process. If you are unable to do so, fax the completed form to the Editorial Office at (214) 648-0881. (Source: Biological Psychiatry)
Source: Biological Psychiatry - October 30, 2009 Category: Psychiatry Tags: Frontmatter Source Type: journals
Guide for Authors
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Biological Psychiatry is the official journal of the Society of Biological Psychiatry. The Journal rapidly publishes reports of novel results on a broad range of topics related to the pathophysiology and treatment of major neuropsychiatric disorders. Both basic and clinical neuroscience contributions are encouraged, particularly those addressing genetic and environmental risk factors, neural circuitry and neurochemistry, and important new therapeutic approaches. (Source: Biological Psychiatry)
Source: Biological Psychiatry - October 30, 2009 Category: Psychiatry Tags: Frontmatter Source Type: journals
Table of Contents
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(Source: Biological Psychiatry)
Source: Biological Psychiatry - October 30, 2009 Category: Psychiatry Tags: Frontmatter Source Type: journals
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Biological Psychiatry (ISSN 0006-3223) is published semimonthly by Elsevier Inc., 360 Park Avenue South, New York, NY 10010-1710. Periodicals postage paid at New York, NY and additional mailing offices. (Source: Biological Psychiatry)
Source: Biological Psychiatry - October 30, 2009 Category: Psychiatry Tags: Frontmatter Source Type: journals
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Source: Biological Psychiatry - October 30, 2009 Category: Psychiatry Tags: Frontmatter Source Type: journals
The following Biological Psychiatry articles in press are now available in full text at http://www.sobp.org/journal
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Our goal is to rapidly disseminate information to our readers. Pre-publication abstracts of accepted articles are posted on our website weekly, and upon availability of a corrected proof, full articles are immediately posted and citable. Articles posted since the last issue are listed below. Interested readers are encouraged to contact authors directly for information prior to publication and to read the associated article in its entirety upon publication. (Source: Biological Psychiatry)
Source: Biological Psychiatry - October 30, 2009 Category: Psychiatry Tags: On the Internet Source Type: journals
Erratum
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An error in the affiliation listing for author Ivan Berlin has been discovered in “Reduced Monoamine Oxidase A Activity in Pregnant Smokers and in Their Newborns” by Berlin et al., which appeared in Biological Psychiatry, Volume 66, Number 8 (2009;66:728–733). Dr. Berlin's complete affiliation is Faculté de médicine, Université Paris 6, Hôpital Pitié-Salpêtrière, INSERM U894, Paris, France. (Source: Biological Psychiatry)
Source: Biological Psychiatry - October 30, 2009 Category: Psychiatry Tags: Erratum Source Type: journals
Autism: The Ups and Downs of Neuroligin
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The etiology of autism spectrum disorders (ASD), like many other neurodevelopmental disorders, has a significant contribution from genetic sources. Among the first genetic causes of ASD identified were a number of rare chromosomal disorders (). However, these conditions were not really considered causes of idiopathic, “mainstream” autism by many because most of these nonidiopathic disorders had dysmorphic features or other signs that were distinguishable from idiopathic autism. Also, like most other common medical conditions, ASD was presumed to be caused primarily by common genetic variation, under a model whereby a c...
Source: Biological Psychiatry - October 30, 2009 Category: Psychiatry Authors: Daniel H. Geschwind Tags: Commentary Source Type: journals
A brief summary of the articles appearing in this issue of Biological Psychiatry
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Abnormalities in synapse formation have been described in post-mortem brain tissue from individuals with autism. Daoud et al. (pages 906–910) provide new evidence that a gene that codes for a protein that plays an important role in synapse formation, NLGN4X, is involved in the genetics of autism. They identified a de novo variation in the promotor region of NLGN4X that may be associated with autism. This mutation increased expression levels of the NLGN4X transcripts in a patient with autism and nonsyndromic profound mental retardation. This result provides further insight about the syndromes that might be associated with...
Source: Biological Psychiatry - October 30, 2009 Category: Psychiatry Source Type: journals
Manuscript Submission Form—Biological Psychiatry
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Section 1: Instructions. A copy of this form, with signatures included from ALL authors on the manuscript, must accompany every new manuscript submission before it will be considered for publication. Please fully complete to eliminate delays in submission. Use an additional form if there are more than 10 authors. Please scan this completed form and attach it electronically during the submission process. If you are unable to do so, fax the completed form to the Editorial Office at (214) 648-0881. (Source: Biological Psychiatry)
Source: Biological Psychiatry - October 15, 2009 Category: Psychiatry Tags: Frontmatter Source Type: journals
Guide for Authors
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Biological Psychiatry is the official journal of the Society of Biological Psychiatry. The Journal rapidly publishes reports of novel results on a broad range of topics related to the pathophysiology and treatment of major neuropsychiatric disorders. Both basic and clinical neuroscience contributions are encouraged, particularly those addressing genetic and environmental risk factors, neural circuitry and neurochemistry, and important new therapeutic approaches. (Source: Biological Psychiatry)
Source: Biological Psychiatry - October 15, 2009 Category: Psychiatry Tags: Frontmatter Source Type: journals
Table of Contents
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(Source: Biological Psychiatry)
Source: Biological Psychiatry - October 15, 2009 Category: Psychiatry Tags: Frontmatter Source Type: journals
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Biological Psychiatry (ISSN 0006-3223) is published semimonthly by Elsevier Inc., 360 Park Avenue South, New York, NY 10010-1710. Periodicals postage paid at New York, NY and additional mailing offices. (Source: Biological Psychiatry)
Source: Biological Psychiatry - October 15, 2009 Category: Psychiatry Tags: Frontmatter Source Type: journals
Editorial Board
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Source: Biological Psychiatry - October 15, 2009 Category: Psychiatry Tags: Frontmatter Source Type: journals
The following Biological Psychiatry articles in press are now available in full text at http://www.sobp.org/journal
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Our goal is to rapidly disseminate information to our readers. Pre-publication abstracts of accepted articles are posted on our website weekly, and upon availability of a corrected proof, full articles are immediately posted and citable. Articles posted since the last issue are listed below. Interested readers are encouraged to contact authors directly for information prior to publication and to read the associated article in its entirety upon publication. (Source: Biological Psychiatry)
Source: Biological Psychiatry - October 15, 2009 Category: Psychiatry Tags: On the Internet Source Type: journals
Epigenetics in Suicide and Depression
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Underlying causes of major depressive disorder (MDD) remain an enigma. A major gain of uncovering mechanisms leading to this devastating disorder will be the prevention of suicide, the worst outcome of MDD. In the search to understand the neurobiology of MDD, several promising hypotheses have been formulated. These hypotheses are largely focused on alterations in monoaminergic neurotransmission, trophic factor signaling, neurogenesis, and glial development and transport. However, recent evidence may potentially bring together all of these hypotheses and offer a basis for understanding the complexity of MDD. This process in...
Source: Biological Psychiatry - October 15, 2009 Category: Psychiatry Authors: Anita E. Autry, Lisa M. Monteggia Tags: Commentary Source Type: journals
A brief summary of the articles appearing in this issue of Biological Psychiatry
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A new study of human brain tissue from suicide victims may provide insights into the neurobiology of suicide. Klempan et al. (pages 824–831) provide evidence for reduced QKI gene expression levels and levels of the QKI protein in the brains of suicide victims with major depression compared to controls, across multiple brain regions. No evidence of genetic or epigenetic changes in the vicinity of the QKI locus was identified. These alterations suggest that deficits in myelination-related pathways may underlie multiple psychiatric disorders. (Source: Biological Psychiatry)
Source: Biological Psychiatry - October 15, 2009 Category: Psychiatry Source Type: journals
Manuscript Submission Form—Biological Psychiatry
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Section 1: Instructions. A copy of this form, with signatures included from ALL authors on the manuscript, must accompany every new manuscript submission before it will be considered for publication. Please fully complete to eliminate delays in submission. Use an additional form if there are more than 10 authors. Please scan this completed form and attach it electronically during the submission process. If you are unable to do so, fax the completed form to the Editorial Office at (214) 648-0881. (Source: Biological Psychiatry)
Source: Biological Psychiatry - October 5, 2009 Category: Psychiatry Tags: Frontmatter Source Type: journals
Guide for Authors
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Biological Psychiatry is the official journal of the Society of Biological Psychiatry. The Journal rapidly publishes reports of novel results on a broad range of topics related to the pathophysiology and treatment of major neuropsychiatric disorders. Both basic and clinical neuroscience contributions are encouraged, particularly those addressing genetic and environmental risk factors, neural circuitry and neurochemistry, and important new therapeutic approaches. (Source: Biological Psychiatry)
Source: Biological Psychiatry - October 5, 2009 Category: Psychiatry Tags: Frontmatter Source Type: journals
Table of Contents
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(Source: Biological Psychiatry)
Source: Biological Psychiatry - October 5, 2009 Category: Psychiatry Tags: Frontmatter Source Type: journals
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Biological Psychiatry (ISSN 0006-3223) is published semimonthly by Elsevier Inc., 360 Park Avenue South, New York, NY 10010-1710. Periodicals postage paid at New York, NY and additional mailing offices. (Source: Biological Psychiatry)
Source: Biological Psychiatry - October 5, 2009 Category: Psychiatry Tags: Frontmatter Source Type: journals
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Source: Biological Psychiatry - October 5, 2009 Category: Psychiatry Tags: Frontmatter Source Type: journals
The following Biological Psychiatry articles in press are now available in full text at http://www.sobp.org/journal
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Our goal is to rapidly disseminate information to our readers. Pre-publication abstracts of accepted articles are posted on our website weekly, and upon availability of a corrected proof, full articles are immediately posted and citable. Articles posted since the last issue are listed below. Interested readers are encouraged to contact authors directly for information prior to publication and to read the associated article in its entirety upon publication. (Source: Biological Psychiatry)
Source: Biological Psychiatry - October 5, 2009 Category: Psychiatry Tags: On the Internet Source Type: journals
Erratum
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A labeling error has been discovered in “Catechol-O-Methyltransferase Valine158 Methionine Polymorphism Modulates Brain Networks Underlying Working Memory Across Adulthood” by Sambataro et al., which appeared in Biological Psychiatry, Volume 66, Number 6 (2009;66:540–548). Specifically, in the key for , met/met and val/val were inadvertently reversed. Therefore, met/met is actually represented by black coloring and val/val by gray coloring. , with the corrected key, is presented here. (Source: Biological Psychiatry)
Source: Biological Psychiatry - October 5, 2009 Category: Psychiatry Tags: Erratum Source Type: journals
Found in Translation: Understanding Impulsivity and Related Constructs Through Integrative Preclinical and Clinical Research
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Addictions are among the most costly disorders, estimated at over $500 billion annually. The multidimensional construct of impulsivity has received increased attention recently as a potential endophenotype for addictions. As questions relating to how best to define and categorize addictions are being discussed in anticipation of DSM-V, a growing role for empirical, neurobiological understandings of addictions exists. Given that this process involves gathering, analyzing, and synthesizing data from multiple lines of investigation, the importance of translational, interdisciplinary research has never been greater. Here, we h...
Source: Biological Psychiatry - October 5, 2009 Category: Psychiatry Authors: Marc N. Potenza, Jane R. Taylor Tags: Commentary Source Type: journals
A brief summary of the articles appearing in this issue of Biological Psychiatry
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Impulsivity is related to ventral striatal activation during reward anticipation in patients with alcohol dependence (AD). Beck et al. (pages 734–742) found that reduced activation of the ventral striatum during reward anticipation was associated with high impulsivity in AD patients using functional magnetic resonance imaging. These findings suggest that dysfunctional reward anticipation and heightened impulsivity are important features of AD. (Source: Biological Psychiatry)
Source: Biological Psychiatry - October 5, 2009 Category: Psychiatry Source Type: journals
Mixture Model Clustering of Phenotype Features Reveals Evidence for Association of DTNBP1 to a Specific Subtype of Schizophrenia
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Conclusions: In the Finnish population, DTNBP1 gene is associated with a schizophrenia phenotype characterized by prominent negative symptoms, generalized cognitive impairment, and few mood symptoms. Identification of genes and pathways related to schizophrenia necessitates novel definitions of disease phenotypes associated more directly with underlying biology. (Source: Biological Psychiatry)
Source: Biological Psychiatry - September 28, 2009 Category: Psychiatry Authors: Jaana Wessman, Tiina Paunio, Annamari Tuulio-Henriksson, Mikko Koivisto, Timo Partonen, Jaana Suvisaari, Joni A. Turunen, Juho Wedenoja, William Hennah, Olli P.H. Pietiläinen, Jouko Lönnqvist, Heikki Mannila, Leena Peltonen Tags: Archival Reports Source Type: journals
Atypical Face Versus Object Processing and Hemispheric Asymmetries in 10-Month-Old Infants at Risk for Autism
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Conclusions: Genetic risk for ASD is associated with atypical face versus object processing and an atypical lack of hemispheric asymmetry early in life. These atypicalities might contribute to development of the disorder. (Source: Biological Psychiatry)
Source: Biological Psychiatry - September 22, 2009 Category: Psychiatry Authors: Joseph P. McCleery, Natacha Akshoomoff, Karen R. Dobkins, Leslie J. Carver Tags: Archival Reports Source Type: journals
The Role of DNA Copy Number Variation in Schizophrenia
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Schizophrenia is a major psychiatric disease with strong evidence of genetic risk factors. Recent studies based on genome-wide study of copy number variations (CNVs) have detected novel recurrent submicroscopic copy number changes, including recurrent deletions at 1q21.11, 15q11.3, 15q13.3, and the recurrent CNV at the 2p16.3 neurexin 1 locus. These schizophrenia susceptibility CNV loci demonstrate that schizophrenia is, at least in part, genetic in origin and provide the basis for further investigation of mutations associated with the disease. The studies combined have also established the role of rare and—in sporadic c...
Source: Biological Psychiatry - September 14, 2009 Category: Psychiatry Authors: Gloria W.C. Tam, Richard Redon, Nigel P. Carter, Seth G.N. Grant Tags: Review Source Type: journals
Phthalates Exposure and Attention-Deficit/Hyperactivity Disorder in School-Age Children
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Conclusion: The present study showed a strong positive association between phthalate metabolites in urine and symptoms of ADHD among school-age children. (Source: Biological Psychiatry)
Source: Biological Psychiatry - September 14, 2009 Category: Psychiatry Authors: Bung-Nyun Kim, Soo-Churl Cho, Yeni Kim, Min-Sup Shin, Hee-Jeong Yoo, Jae-Won Kim, Young Hee Yang, Hyo-Won Kim, Soo-Young Bhang, Yun-Chul Hong Tags: Archival Reports Source Type: journals
A Meta-Analysis of the Corpus Callosum in Autism
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Conclusions: Corpus callosum reductions are present in autism and support the aberrant connectivity hypothesis. Future diffusion tensor imaging studies examining specific fiber tracts connecting the hemispheres are needed to identify the cortical regions most affected by CC reductions. (Source: Biological Psychiatry)
Source: Biological Psychiatry - September 14, 2009 Category: Psychiatry Authors: Thomas W. Frazier, Antonio Y. Hardan Tags: Archival Reports Source Type: journals
Manuscript Submission Form—Biological Psychiatry
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Section 1: Instructions. A copy of this form, with signatures included from ALL authors on the manuscript, must accompany every new manuscript submission before it will be considered for publication. Please fully complete to eliminate delays in submission. Use an additional form if there are more than 10 authors. Please scan this completed form and attach it electronically during the submission process. If you are unable to do so, fax the completed form to the Editorial Office at (214) 648-0881. (Source: Biological Psychiatry)
Source: Biological Psychiatry - September 10, 2009 Category: Psychiatry Tags: Frontmatter Source Type: journals
Guide for Authors
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Biological Psychiatry is the official journal of the Society of Biological Psychiatry. The Journal rapidly publishes reports of novel results on a broad range of topics related to the pathophysiology and treatment of major neuropsychiatric disorders. Both basic and clinical neuroscience contributions are encouraged, particularly those addressing genetic and environmental risk factors, neural circuitry and neurochemistry, and important new therapeutic approaches. (Source: Biological Psychiatry)
Source: Biological Psychiatry - September 10, 2009 Category: Psychiatry Tags: Frontmatter Source Type: journals
Table of Contents
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(Source: Biological Psychiatry)
Source: Biological Psychiatry - September 10, 2009 Category: Psychiatry Tags: Frontmatter Source Type: journals
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Biological Psychiatry (ISSN 0006-3223) is published semimonthly by Elsevier Inc., 360 Park Avenue South, New York, NY 10010-1710. Periodicals postage paid at New York, NY and additional mailing offices. (Source: Biological Psychiatry)
Source: Biological Psychiatry - September 10, 2009 Category: Psychiatry Tags: Frontmatter Source Type: journals
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Source: Biological Psychiatry - September 10, 2009 Category: Psychiatry Tags: Frontmatter Source Type: journals
The following Biological Psychiatry articles in press are now available in full text at http://www.sobp.org/journal
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Our goal is to rapidly disseminate information to our readers. Pre-publication abstracts of accepted articles are posted on our website weekly, and upon availability of a corrected proof, full articles are immediately posted and citable. Articles posted since the last issue are listed below. Interested readers are encouraged to contact authors directly for information prior to publication and to read the associated article in its entirety upon publication. (Source: Biological Psychiatry)
Source: Biological Psychiatry - September 10, 2009 Category: Psychiatry Tags: On the Internet Source Type: journals
The Silent Epidemic of Neurodevelopmental Injuries
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Childhood maltreatment in the United States was recently recognized as a major public health problem by several influential sources including the World Health Organization and the Institute of Medicine (). An extensive survey conducted by the National Incidence of Child Abuse and Neglect (NIS3) revealed that roughly 1.5 million children were abused or neglected in 1993. This number of documented cases most likely underestimates the true prevalence, given that many cases of maltreatment go unrecognized (). Moreover, according to the three available NIS reports, the incidence of childhood maltreatment has been steadily incre...
Source: Biological Psychiatry - September 10, 2009 Category: Psychiatry Authors: Arie Kaffman Tags: Commentary Source Type: journals
A brief summary of the articles appearing in this issue of Biological Psychiatry
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A new study addresses the ongoing debate regarding whether childhood psychological traumatization impairs cortical development. Tomoda et al. (pages 642–648) provide evidence that exposure to repeated episodes of childhood sexual abuse is associated with reduced gray matter volume in left and right visual and visual association cortices. Reduced visual cortex gray matter volume was associated with duration of abuse prior to 12 years of age, and correlated with visual memory. (Source: Biological Psychiatry)
Source: Biological Psychiatry - September 10, 2009 Category: Psychiatry Source Type: journals
Microstructural Organization of Cerebellar Tracts in Schizophrenia
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Conclusions: Though structural connectivity is impaired in the cerebellum, it is not local to any particular tract but appears to have a wider, possibly global, distribution. Reduced fractional anisotropy with normal MD would point to the differences being due to disordered neuronal architecture rather than disordered myelination. (Source: Biological Psychiatry)
Source: Biological Psychiatry - September 7, 2009 Category: Psychiatry Authors: Richard A.A. Kanaan, Stefan Borgwardt, Philip K. McGuire, Michael C. Craig, Declan G.M. Murphy, Marco Picchioni, Sukhwinder S. Shergill, Derek K. Jones, Marco Catani Tags: Brief Report Source Type: journals
Efficacy of Using Cognitive Status in Predicting Psychosis: A 7-Year Follow-Up
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Background: Despite extensive early detection research in schizophrenic psychoses, methods for identifying at-risk individuals and predicting their transition to psychosis are still unreliable. Moreover, there are sparse data on long-term prediction. We therefore investigated long-term psychosis transition in individuals with an At Risk Mental State (ARMS) and examined the relative efficacy of clinical and neuropsychological status in optimizing the prediction of transition.Methods: Sixty-four individuals with ARMS for psychosis were identified from all referrals to our early detection clinic between March 1, 2000 and Febr...
Source: Biological Psychiatry - September 7, 2009 Category: Psychiatry Authors: Anita Riecher-Rössler, Marlon O. Pflueger, Jacqueline Aston, Stefan J. Borgwardt, Warrick J. Brewer, Ute Gschwandtner, Rolf-Dieter Stieglitz Tags: Archival Reports Source Type: journals
