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482 records returned

An Epidemiological Survey of Blood Lead Level in Tibetan Youth 10-18 Years Old in Songpan, China.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The objective of this project was to conduct a preliminary investigation on the blood lead level of Tibetan youth. Chinese Han youth's BLL was also investigated as a control group. A total of 846 Tibetan youth and 785 Han youth were tested for BLL from September to October in 2007. Both of the mean BLL (6.4 mug/dL) and the frequency of high BLL (>/=10 mug/dL) of Tibetan youth (7.7%, 65 of 846) were lower than those of Han youth (6.7 mug/dL; 13.2%, 104 of 785). But they are still higher compared with the BLL of youth in developed countries (1.1 microg/dL; USA 2005 census). The BLL of boys was significantly higher than th...
Source: Biological Trace Element Research - November 18, 2009 Category: Biology Authors: Zhou W, Jiang Y, Shi H, Liu J, Shen C, Dai Q, Yang H Tags: Biol Trace Elem Res Source Type: journals

Interstitial Lung Disease in Coppersmiths in High Serum Copper Levels.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Coppersmith is a worker who uses copper most commonly for the production of kitchen appliances in Turkey. This is an ancient occupation practiced for centuries in Turkey. Our objective was to investigate the prevalence of parenchymal lung diseases among coppersmiths in Kahramanmaras city in Turkey. Thirty coppersmiths were included to the study, and they all signed an informed consent. Demographics, spirometric test results and high-resolution computed tomography (HRCT) scans, and blood samples were obtained. Laboratory analysis of the serum samples showed that serum copper levels of the subjects were 0.93 +/- 0.14 mg/...
Source: Biological Trace Element Research - November 17, 2009 Category: Biology Authors: Dagli CE, Tanrikulu AC, Koksal N, Abakay A, Gelen ME, Demirpolat G, Yuksel M, Atilla N, Tolun FI Tags: Biol Trace Elem Res Source Type: journals

The Association of Metallothionein-4 Gene Polymorphism and Renal Function in Long-Term Lead-Exposed Workers.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The goal of this study is to investigate if metallothionein (MT) gene polymorphism affects the susceptibility to lead as well as renal function parameters and blood pressures (BP) in workers exposed to lead for extended period of time. By means of real-time polymerase chain reaction, the MT4-216 A/G genotypes classified as rs396230 in the single nucleotide polymorphism database of the National Center for Biotechnology Information (database) were analyzed on 113 workers of a lead battery-recycling factory. Workers with G (mutant) allele were more susceptible to the toxic effects of lead on their systolic BP and serum re...
Source: Biological Trace Element Research - November 17, 2009 Category: Biology Authors: Chen HI, Chiu YW, Hsu YK, Li WF, Chen YC, Chuang HY Tags: Biol Trace Elem Res Source Type: journals

Elevation of PTH and PTHrp Induced by Excessive Fluoride in Rats on a Calcium-deficient Diet.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Study on the role of parathyroid hormone (PTH) and parathyroid hormone-related peptide (PTHrp) in the process of skeletal fluorosis, involved especially in calcium deficiency, is rare. We evaluated the level of serum PTH and mRNA expression of PTHrp in femur when rats were exposed to excessive fluoride with low-calcium diet. Wistar rats (n = 60) was divided into four groups, a control group, fluoride group, low-calcium group, and low-calcium fluoride group. The fluoride groups were treated with fluoride by drinking tap water containing 100 mg F-/L. The low-calcium diet contained 0.05% calcium. Serum was collected in th...
Source: Biological Trace Element Research - November 14, 2009 Category: Biology Authors: Xu H, Liu QY, Zhang JM, Zhang H, Li GS Tags: Biol Trace Elem Res Source Type: journals

Microcalorimetric Study of Tetrahymena Growth Affected by Copper(II) Complexes.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
By means of microcalorimetry, the effect of four copper(II) complexes on Tetrahymena growth was investigated. The extent and duration of the inhibitory effect on the metabolism, judged by the rate constant, k, and the half inhibition concentration, IC(50), varied with the different complexes. The results showed that the half inhibition concentrations IC(50) of CuCl(2), (C(9)H(6)NO)(2)Cu and [Cu(phen)(2)]Cl(2)[Symbol: see text]6H(2)O were 9.9 x 10(-4), 2.0 x 10(-4), and 2.6 x 10(-4) mol/L, respectively. The sequence of antibiotic activity of these three complexes was: (C(9)H(6)NO)(2)Cu > [Cu(phen)(2)]Cl(2)[Symbol: se...
Source: Biological Trace Element Research - November 13, 2009 Category: Biology Authors: Xi L, Tian Z, Hongyu X, Peng L Tags: Biol Trace Elem Res Source Type: journals

Gender Differences in Elements of Human Anterior Commissure and Olfactory Bulb and Tract.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To examine whether there were gender differences in the various brain regions, the authors investigated the gender differences in seven element contents of the anterior commissure, mammillary body, and olfactory bulb and tract by direct chemical analysis. After ordinary dissection at Nara Medical University was finished, the anterior commissures, mammillary bodies, and olfactory bulbs and tracts were resected from the cerebra cut at median line. The brain samples were treated with 99.5% ethanol three times to remove lipids. After ashing with nitric acid and perchloric acid, the seven element contents Ca, P, S, Mg, Zn, ...
Source: Biological Trace Element Research - November 12, 2009 Category: Biology Authors: Tohno S, Ongkana N, Ke L, Mahakkanukrauh P, Minami T, Suwannahoy P, Sinthubua A, Tohno Y Tags: Biol Trace Elem Res Source Type: journals

Effect of Fluoride Exposure on Serum Glycoprotein Pattern and Sialic Acid Level in Rabbits.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study describes the effects of fluoride exposure on the protein profile, glycoprotein pattern, and total sialic acid concentration of serum in rabbits. For this aim; 20 healthy New Zealand rabbits were used. The rabbits were divided into two equal groups each with ten animals according to their weighing: control group and experimental group. The rabbits in control group were given drinking tap water containing 0.29 mg/l sodium fluoride and experimental group received the same tap water to which was added 40 mg/l sodium fluoride for 70 days. Blood samples were taken from each rabbit on day 70. Serum fluoride concentrat...
Source: Biological Trace Element Research - November 11, 2009 Category: Biology Authors: Ciftci G, Cenesiz S, Yarim GF, Nisbet O, Nisbet C, Cenesiz M, Guvenc D Tags: Biol Trace Elem Res Source Type: journals

Effects of Lead and/or Cadmium on the Oxidative Damage of Rat Kidney Cortex Mitochondria.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, there was an obvious synergistic oxidative damage effect of lead combined with cadmium on rat kidney cortex mitochondria, which increased defects in mitochondrial oxidative metabolism. PMID: 19902158 [PubMed - as supplied by publisher] (Source: Biological Trace Element Research)
Source: Biological Trace Element Research - November 10, 2009 Category: Biology Authors: Wang L, Li J, Li J, Liu Z Tags: Biol Trace Elem Res Source Type: journals

Chromium III Histidinate Exposure Modulates Gene Expression in HaCaT Human Keratinocytes Exposed to Oxidative Stress.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
While the toxicity of hexavalent chromium is well established, trivalent chromium is an essential nutrient involved in insulin and glucose homeostasis. To study the antioxidant effects of Cr(III)His, cDNA arrays were used to investigate the modulation of gene expression by trivalent chromium histidinate (Cr(III)His) in HaCaT human keratinocytes submitted to hydrogen peroxide (H(2)O(2)). Array was composed by a set of 81 expressed sequences tags (ESTs) essentially represented by antioxidant and DNA repair genes. HaCaT were preincubated for 24 h with 50 muM Cr(III)His and were treated with 50 muM H(2)O(2). Total RNAs wer...
Source: Biological Trace Element Research - November 10, 2009 Category: Biology Authors: Hazane-Puch F, Benaraba R, Valenti K, Osman M, Laporte F, Favier A, Anderson RA, Roussel AM, Hininger-Favier I Tags: Biol Trace Elem Res Source Type: journals

Prophylactic Efficacy of Coriandrum sativum (Coriander) on Testis of Lead-Exposed Mice.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Lead poisoning is a worldwide health problem, and its treatment is under investigation. The aim of this study was to access the efficacy of Coriandrum sativum (coriander) in reducing lead-induced changes in mice testis. Animal exposed to lead nitrate showed significant decrease in testicular SOD, CAT, GSH, total protein, and tissue lead level. This was accompanied by simultaneous increase in the activities of LPO, AST, ALT, ACP, ALP, and cholesterol level. Serum testosterone level and sperm density were suppressed in lead-treated group compared with the control. These influences of lead were prevented by concurrent dai...
Source: Biological Trace Element Research - November 10, 2009 Category: Biology Authors: Sharma V, Kansal L, Sharma A Tags: Biol Trace Elem Res Source Type: journals

Brain Trace Element Concentration of Rats Treated with the Plant Alkaloid, Vincamine.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The objective of this study was to determine the level of zinc (Zn), copper (Cu), iron (Fe), Selenium (Se), and chromium (Cr) in the brain of rats treated with vincamine. Vincamine was injected i.m. to rats at a dose of 15 mg/Kg bodyweight daily for 14 days. Twenty-four hours after the last injection, rats were killed, and brains were ashed and digested by concentrated acids and analyzed for trace elements concentrations by flame emission atomic absorption spectrophotometer. The results showed that Zn was the highest trace element in the brain of control rats (3.134 +/- 0.072 ppm) and Cr was the lowest (0.386 +/- 0.027 ppm...
Source: Biological Trace Element Research - November 10, 2009 Category: Biology Authors: Fayed AH Tags: Biol Trace Elem Res Source Type: journals

Transcription of the Epstein-Barr Virus Lytic Cycle Activator BZLF-1 During Oxidative Stress Induction.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
While latent Epstein-Barr virus infection can be in vitro reactivated by various reagents such as 12-0-tetradecanoylphorbol-13-acetate and calcium ionophore, relatively little is known about in vivo physiological and biochemical factors implicated in this reactivation. Previous studies have described an association between oxidative stress and Epstein-Barr virus infection. In this present study, we investigated the effect of oxidative stress inductors: H(2)O(2) and FeSO(4) on reactivation of EBV through BZLF-1 gene expression. Oxidative stress was induced in Raji cell line with 0.2 mM H(2)O(2) or with 0.1 mM FeSO(4), a...
Source: Biological Trace Element Research - November 7, 2009 Category: Biology Authors: Lassoued S, Gargouri B, El Feki AE, Attia H, Van Pelt J Tags: Biol Trace Elem Res Source Type: journals

The Effect of Age and Gender on 38 Chemical Element Contents in Human Femoral Neck Investigated by Instrumental Neutron Activation Analysis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The effect of age and gender on 38 chemical element contents in femoral neck of 85 apparently healthy 15-55-year-old women (n = 38) and men (n = 47) was investigated by instrumental neutron activation analysis. Mean values (M +/- SEpsilonMu) for mass fraction (on dry weight basis) of Ca, Cl, Co, Fe, K, Mg, Mn, Na, P, Sr, and Zn for both female and male taken together were: Ca 153 +/- 3 g/kg, Cl 1,188 +/- 48 mg/kg, Co 0.0039 +/- 0.0004 mg/kg, Fe 55.5 +/- 8.8 mg/kg, K 490 +/- 22 mg/kg, Mg 1,940 +/- 48 mg/kg, Mn 0.385 +/- 0.015 mg/kg, Na 3,850 +/- 70 mg/kg, P 73.0 +/- 1.5 g/kg, Sr 288 +/- 18 mg/kg, and Zn 55.5 +/- 1.6 mg/...
Source: Biological Trace Element Research - November 7, 2009 Category: Biology Authors: Zaichick S, Zaichick V Tags: Biol Trace Elem Res Source Type: journals

Trace Elements Contents in Asparagus curillus (Buch.-Ham.) ex Roxb.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Concentration level of nine elements viz. Zn, Cu, Mn, Fe, Co, Na, K, Ca, and Li were determined in leaves and roots of Asparagus curillus (Buch.-Ham.) ex Roxb. collected from four different altitudes in three seasons by atomic absorption spectroscopy. The overall concentration of K was found to be highest, whereas the level of Cu was lowest. The maximum concentrations of Zn, Cu, Mn, Fe, Co, Na, K, Ca, and Li were found to be 97.0 +/- 1.5, 28.0 +/- 7.0, 44.0 +/- 7.3, 1138.0 +/- 18.5, 91.0 +/- 6.2, 381.0 +/- 7.8, 9508.0 +/- 7.8, 3076.0 +/- 6.4, and 78.0 +/- 4.6 mg/kg, respectively. PMID: 19865802 [PubMed - as supplie...
Source: Biological Trace Element Research - October 29, 2009 Category: Biology Authors: Negi JS, Singh P, Nee Pant GJ, Rawat MS Tags: Biol Trace Elem Res Source Type: journals

Urine Iodine Levels in Preeclamptic and Normal Pregnant Women.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The aim of this study was to investigate the urine iodine concentration in women with severe preeclampsia and in healthy women in Erzurum, Turkey. Urine specimens were obtained from 40 severe preeclampsia and 18 healthy pregnant women. Urinary iodine levels were determined by the Foss method based on the Sandell-Kolthoff reaction. The urinary iodine level for women with severe preeclampsia was 4.25 +/- 2.7 microg/dL, lower than 20.89 +/- 6.4 microg/dL of urinary iodine for healthy pregnant women (p < 0.001). Blood magnesium concentration was found to be 1.63 +/- 0.05 mg/dL for women with severe preeclampsia, which i...
Source: Biological Trace Element Research - October 29, 2009 Category: Biology Authors: Gulaboglu M, Borekci B, Delibas I Tags: Biol Trace Elem Res Source Type: journals

Absence of Binding Between the Human Transferrin Receptor and the Transferrin Complex of Biological Toxic Trace Element, Aluminum, Because of an Incomplete Open/Closed Form of the Complex.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Human transferrin (Tf) very tightly binds two ferric ions to deliver iron to cells. Fe(III)(2)Tf (Fe(2)Tf) binds to the Tf receptor (TfR) at pH 7.4; however, iron-free Tf (apoTf) does not. Iron uptake is facilitated by endocytosis of the Fe(2)Tf-TfR complex. Tf can also bind aluminum ions, which cause toxic effects and are associated with many diseases. Since Al(III)(2)Tf (Al(2)Tf) does not bind to TfR, the uptake of aluminum by the cells does not occur through a TfR-mediated pathway. We have studied the absence of binding between Al(2)Tf and TfR by investigating the physicochemical characteristics of apoTf, Al(2)Tf, F...
Source: Biological Trace Element Research - October 27, 2009 Category: Biology Authors: Sakajiri T, Yamamura T, Kikuchi T, Ichimura K, Sawada T, Yajima H Tags: Biol Trace Elem Res Source Type: journals

Lead and Arsenic Levels in Women with Different Body Mass Composition.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The objective of this study was to evaluate whether lead (Pb) and arsenic (As) levels in biological fluids were associated to the body composition in a group of reproductive-age women. Voluntary childbearing-age women (n = 107) were divided into three groups according to their body mass index (BMI: weight/height(2) (kg/m(2)): low weight (BMI<18.5 kg/m(2)), normal [Formula: see text], and overweight (BMI>25 kg/m(2)). Body composition and fat mass percentage were determined by the isotopic dilution method utilizing deuterated water. Blood lead concentrations were determined by graphite furnace atomic absorption spectro...
Source: Biological Trace Element Research - October 23, 2009 Category: Biology Authors: Ronco AM, Gutierrez Y, Gras N, Muñoz L, Salazar G, Llanos MN Tags: Biol Trace Elem Res Source Type: journals

Effects of Manganese Deficiency on Spectral Characteristics and Oxygen Evolution in Maize Chloroplasts.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The effects of Mn(2+) deficiency on light absorption, transmission, and oxygen evolution of maize chloroplasts were investigated by spectral methods. Several effects of Mn(2+) deficiency were observed: (1) the skeleton of pigment protein complexes and oxygen-evolving center and the combination between pigment and protein were damaged; (2) the light absorption of chloroplasts was obviously decreased; (3) the energy transfer among amino acids within PS II protein-pigment complex and decreased energy transport from tyrosine residue to chlorophyll a and from chlorophyll b and carotenoid to chlorophyll a were inhibited; (4)...
Source: Biological Trace Element Research - October 19, 2009 Category: Biology Authors: Gong X, Wang Y, Liu C, Wang S, Zhao X, Zhou M, Li N, Lu Y, Hong F Tags: Biol Trace Elem Res Source Type: journals

Interaction Between Nanoparticulate Anatase TiO(2) and Lactate Dehydrogenase.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In order to study the mechanisms underlying the effects of TiO(2) nanoparticles on lactate dehydrogenase (LDH, EC1.1.1.27), Institute of Cancer Research region mice were injected with nanoparticulate anatase TiO(2) (5 nm) of various doses into the abdominal cavity daily for 14 days. We then examined LDH activity in vivo and in vitro and direct evident for interaction between nanoparticulate anatase TiO(2) and LDH using spectral methods. The results showed that nanoparticulate anatase TiO(2) could significantly activate LDH in vivo and in vitro; the kinetics constant (Km) and Vmax were 0.006 muM and 1,149 unit mg(-1) pr...
Source: Biological Trace Element Research - October 19, 2009 Category: Biology Authors: Duan Y, Li N, Liu C, Liu H, Cui Y, Wang H, Hong F Tags: Biol Trace Elem Res Source Type: journals

Erratum to: Simultaneous Determination of Cd, Pb, Cu, Zn, and Se in Human Blood of Jordanian Smokers by ICP-OES.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19841871 [PubMed - as supplied by publisher] (Source: Biological Trace Element Research)
Source: Biological Trace Element Research - October 19, 2009 Category: Biology Authors: Massadeh A, Gharibeh A, Omari K, Al-Momani I, Alomary A, Tumah H, Hayajneh W Tags: Biol Trace Elem Res Source Type: journals

Spectroscopic Behavior and Biological Activity of K(2)[VO(O (2))NTA].2H (2)O.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The dihydrated potassium salt of the complex anion [VO(O(2))NTA](2-) (NTA = nitrilotriacetate anion, [N(CH(2)-COO)(3)](3-)) was thoroughly characterized by electronic and vibrational (infrared and Raman) spectroscopies. The bioactivity of the complex on the cell proliferation was tested on three cell lines in culture (UMR106 rat osteosarcoma-derived cells, Caco-2 derived from a human colon adenocarcinoma, and RAW 264.7, a macrophage murine cell line). PMID: 19841872 [PubMed - as supplied by publisher] (Source: Biological Trace Element Research)
Source: Biological Trace Element Research - October 19, 2009 Category: Biology Authors: Arrambide G, Barrio DA, Etcheverry SB, Gambino D, Baran EJ Tags: Biol Trace Elem Res Source Type: journals

The Mechanism of CeCl(3) on the Activiation of Alanine Aminotransferase from Mice.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this report, we investigated the mechanisms of CeCl(3) on ALT activity in vivo and in vitro. Our results showed that Ce(3+) could significantly activate ALT in vivo and in vitro; the kinetics constant (Km) and Vmax were 0.018 microM and 1,380 unit mg(-1) protein min(-1), respectively, at a low concentration of Ce(3+), and 0.027 microM and 624 unit mg(-1) protein min(-1), respectively, at a high concentration of Ce(3+). By UV absorption and fluorescence spectroscopy assays, the Ce(3+) was determined to be directly bound to ALT; the binding site of Ce(3+) to ALT was 1.72, and the binding constants of the binding site were...
Source: Biological Trace Element Research - October 19, 2009 Category: Biology Authors: Li N, Duan Y, Liu C, Hong F Tags: Biol Trace Elem Res Source Type: journals

Inhibition of Both Thioredoxin Reductase and Glutathione Reductase may Contribute to the Anticancer Mechanism of TH-302.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Selenium-containing thioredoxin reductase (TrxR) is an important target of cancer therapy. Many useful anticancer agents including bis-alkylating agents, cisplatin, and arsenic trioxide are known to interact with the selenocysteine dipeptide in the carboxy terminal region of thioredoxin reductase and inactivate its ability to reduce thioredoxin. Some investigators have postulated that the inactivation of TrxR may add to the cytotoxic potential of these anticancer agents. TH-302 is a newly developed antineoplastic drug which represents a potential new class of tumor selective hypoxia-activated prodrugs (HAPs). TH-302 is...
Source: Biological Trace Element Research - October 16, 2009 Category: Biology Authors: Li S, Zhang J, Li J, Chen D, Matteucci M, Curd J, Duan JX Tags: Biol Trace Elem Res Source Type: journals

Sodium Tungstate Attenuate Oxidative Stress in Brain Tissue of Streptozotocin-Induced Diabetic Rats.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, we evaluated effects of sodium tungstate on enzymatic and nonenzymatic markers of oxidative stress in brain of streptozotocin (STZ)-induced diabetic rats. Rats were divided into four groups (ten rats in each group): untreated control, sodium tungstate-treated control, untreated diabetic, and sodium tungstate-treated diabetic. Diabetes was induced with an intraperitoneal STZ injection (65 mg/kg body weight), and sodium tungstate with concentration of 2 g/L was added to drinking water of treated animals for 4 weeks. Diabetes caused a significant increase in the brain thiobarbituric acid reactive substances (P ...
Source: Biological Trace Element Research - October 15, 2009 Category: Biology Authors: Nakhaee A, Bokaeian M, Akbarzadeh A, Hashemi M Tags: Biol Trace Elem Res Source Type: journals

Responses of Wheat Seedlings to Exogenous Selenium Supply Under Cold Stress.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Dose-dependent effects of selenium on growth and physiological trait of wheat seedlings (Triticum aestivum L. cv Han NO.7086) exposed to cold stress are reported. Responses of seedlings were different depending on the Se concentration. The treatments with 0.5 and 1.0 mg Se kg(-1) significantly increased biomass and chlorophyll content of seedlings. However, the treatments at 2.0 and 3.0 mg Se kg(-1) only induced an evident increase in chlorophyll content and did not promote biomass accumulation of seedlings. Antioxidant compounds content (anthocyanins, flavonoids, and phenolic compounds) and antioxidant enzymes' activi...
Source: Biological Trace Element Research - October 14, 2009 Category: Biology Authors: Chu J, Yao X, Zhang Z Tags: Biol Trace Elem Res Source Type: journals

Effects of Copper Supplementation on the Structure and Content of Elements in Kidneys of Mosaic Mutant Mice.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Menkes disease is an effect of ATP7A gene mutation in humans, coding the Cu-ATP-ase which is essential in intestinal copper absorption and its subsequent transfer to circulation. This mutation results in a deficiency of copper in all tissues except the epithelia of intestine and kidney tubules. Subcutaneous injection of copper ions is the main therapy for Menkes patients. Mosaic (Atp7a(mo-ms)) mice closely simulate the situation in Menkes disease. The aim of this study was to evaluate the changes in structure and element content in kidneys of mosaic mice after copper supplementation. Hematoxylin-eosin staining was used...
Source: Biological Trace Element Research - October 14, 2009 Category: Biology Authors: Lenartowicz M, Windak R, Tylko G, Kowal M, Styrna J Tags: Biol Trace Elem Res Source Type: journals

In Vivo Formation and Binding of SeHg Complexes to the Erythrocyte Surface.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The in vivo dynamics of selenium (Se) and mercury (Hg) interaction was studied in mouse tissues using direct visualization of individual Se, Hg, and SeHg particles on the surface of circulating erythrocytes. This high-resolution detection of Se and Hg was obtained by scanning electron microscopy coupled to X-ray microanalysis. BALB/c mice were injected in the peritoneal cavity with Se and Hg salts, and the animals were sacrificed 3 min after the Hg injection. Only a minority (9%) of the metal dots seen on mouse liver erythrocytes were SeHg complexes when Se and Hg salts were mixed together before injection. In contrast...
Source: Biological Trace Element Research - October 14, 2009 Category: Biology Authors: Cherdwongcharoensuk D, João Oliveira M, Aguas AP Tags: Biol Trace Elem Res Source Type: journals

Seleno L-: Methionine Acts on Cyclophosphamide-Induced Kidney Toxicity.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, the present study not only points to the therapeutic potential of SLM in CP-induced kidney toxicity but also indicates a significant role for ROS and their relation to kidney dysfunction. PMID: 19826776 [PubMed - as supplied by publisher] (Source: Biological Trace Element Research)
Source: Biological Trace Element Research - October 13, 2009 Category: Biology Authors: Ayhanci A, Günes S, Sahinturk V, Appak S, Uyar R, Cengiz M, Altuner Y, Yaman S Tags: Biol Trace Elem Res Source Type: journals

Trace Elements Status in Selenium-Deficient Rats-Interaction with Cadmium.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Although the metabolic and toxicological interactions between essential element selenium (Se) and toxic element cadmium (Cd) have been reported for a long time, the experimental studies explored mostly acute, high-dose interactions. Limited data are available regarding the effects of Se-deficiency on toxicokinetics of cadmium, as well as on the levels of key trace elements-copper, zinc, and iron. In the present study, male and female Wistar weanling rats (n = 40/41) were fed either Se-deficient or Se-adequate diet (<0.06 or 0.14 mg Se per kilogram diet, respectively) for 12 weeks, and from week 9 were drinking water...
Source: Biological Trace Element Research - October 12, 2009 Category: Biology Authors: Kotyzová D, Cerná P, Lešetický L, Eybl V Tags: Biol Trace Elem Res Source Type: journals

Trigonella foenum-graecum (Fenugreek) Protects Against Selenite-Induced Oxidative Stress in Experimental Cataractogenesis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Cataract is the opacification in eye lens and leads to 50% of blindness worldwide. The present study was undertaken to evaluate the anticataract potential of Trigonella foenum-graecum Linn seeds (fenugreek) in selenite-induced in vitro and in vivo cataract. In vitro enucleated rat lenses were maintained in organ culture containing Dulbecco's modified Eagles medium (DMEM) alone or in addition with 100 microM selenite and served as the normal and control groups, respectively. For the test group, the medium was supplemented with selenite and T. foenum-graecum aqueous extract. The lenses were incubated for 24 h at 37 degre...
Source: Biological Trace Element Research - October 12, 2009 Category: Biology Authors: Gupta SK, Kalaiselvan V, Srivastava S, Saxena R, Agrawal SS Tags: Biol Trace Elem Res Source Type: journals

Acute Copper Supplementation Does Not Inhibit Non-Heme Iron Bioavailability in Humans.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, combined Cu and Fe administration in an aqueous solution does not inhibit Fe bioavailability. This information could help in the design of rational guidelines for copper and iron supplementation programs. Our results support the hypothesis that divalent metal transporter 1 is not physiologically relevant for copper absorption in humans. PMID: 19820904 [PubMed - as supplied by publisher] (Source: Biological Trace Element Research)
Source: Biological Trace Element Research - October 9, 2009 Category: Biology Authors: Olivares M, Pizarro F, de Romaña DL, Ruz M Tags: Biol Trace Elem Res Source Type: journals

Structural Changes of Cell Wall and Lignifying Enzymes Modulations in Bean Roots in Response to Copper Stress.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Fourteen-day-old bean seedlings were cultured in nutrient solution containing Cu(2+) ions at various concentrations (50 and 75 microM of CuSO(4)) for 3 days. This excess of copper induced a reduction in the water volume absorbed by the plants. Moreover, this reduction was accompanied by an increase of the amount of copper taken up by the roots. Analysis by native gel electrophoresis of cell wall peroxidase activities in the roots revealed a stimulation of two anionic isoforms (A(2) and A(3)) under cupric stress conditions. Moreover, the activity of phenylalanine ammonia lyase (EC. 4.3.1.5), which plays an important rol...
Source: Biological Trace Element Research - October 9, 2009 Category: Biology Authors: Bouazizi H, Jouili H, Geitmann A, El Ferjani E Tags: Biol Trace Elem Res Source Type: journals

Depressed Antioxidant Status in Pregnant Women on Iron Supplements: Pathologic and Clinical Correlates.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Iron (Fe) remains a commonly prescribed supplement in pregnancy. Its possible pathologic potential is either uncommonly considered or ignored. We determined the antioxidant status in pregnant women with and without Fe supplements. Fifty-eight apparently healthy pregnant women on Fe supplements were selected for the study from the antenatal clinic of the University College Hospital, Ibadan, Nigeria. Fifty-five aged matched pregnant women who were not on Fe from various parishes of the Christ Apostolic Church, Ibadan (non-drug using Christian sect) were randomly selected as controls. Both groups were classified according...
Source: Biological Trace Element Research - October 7, 2009 Category: Biology Authors: Anetor JI, Ajose OA, Adeleke FN, Olaniyan-Taylor GO, Fasola FA Tags: Biol Trace Elem Res Source Type: journals

Effects of Artemisinin Derivative on the Growth Metabolism of Tetrahymena thermophila BF5 Based on Expression of Thermokinetics.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The toxic effects of artesunate and dihydroartemisinin on the growth metabolism of Tetrahymena thermophila BF5 were studied by microcalorimetry. The results showed that: (1) low concentrations of artesunate (</=1 mg L(-1)) and dihydroartemisinin (</= 2 mg L(-1)) promoted the growth metabolism of T. thermophila BF5, whereas high concentrations of artesunate (1-60 mg L(-1)) and dihydroartemisinin (2-60 mg L(-1)) inhibited its growth; (2) the half inhibition concentrations IC(50) of artesunate and dihydroartemisinin were 17.5817 and 9.5089 mg L(-1), respectively. It was concluded that the inhibition of dihydroartemi...
Source: Biological Trace Element Research - October 5, 2009 Category: Biology Authors: Shen XS, Su Q, Qiu ZP, Xu JY, Xie YX, Liu HF, Liu Y Tags: Biol Trace Elem Res Source Type: journals

The Content of Elements in Rainwater and its Relation to the Frequency of Hospitalization for Diabetes and Obesity in Opole Voivodship, Poland, During 2000-2002.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Environmental factors significantly influence the incidence and course of metabolic syndrome diseases such as diabetes and obesity. The content of elements in rainwater is an indirect indicator of their presence in dust suspended in the air. In this paper we present the relationships between the content of selected elements in rainwater and hospitalization frequencies due to diabetes (E10-E13) and obesity (E66). It was assumed that the hospitalization frequency could be taken as a measure of deterioration of the metabolic process in the course of diabetes and its complications. The observations concerned the population...
Source: Biological Trace Element Research - October 2, 2009 Category: Biology Authors: Bunio A, Szygula R, Tubek S, Krasowski G Tags: Biol Trace Elem Res Source Type: journals

Effect of Zinc Methionine or Zinc Sulfate Supplementation on Milk Production and Composition of Milk in Lactating Dairy Cows.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Eighteen lactating dairy cows were used to compare the effects of organic and inorganic Zn supplements on milk production and chemical composition of milk. Animals received three diets in a randomized block design: basal diet with no supplemental Zn (control, 42 mg Zn/kg), basal diet plus 500 mg Zn/kg of dry matter (DM) as zinc sulfate monohydrate (ZnS) and basal diet plus 500 mg Zn/kg of DM as zinc methionine (ZnM). Results showed that milk and fat-corrected milk yield in dairy cows were not significantly affected by Zn source although a numerical increase was observed. The percentages of protein, lactose, fat, solid ...
Source: Biological Trace Element Research - October 2, 2009 Category: Biology Authors: Sobhanirad S, Carlson D, Bahari Kashani R Tags: Biol Trace Elem Res Source Type: journals

Effects of Vitamins C and E Combination on Element Levels in Blood of Smoker and Nonsmoker Radiology X-Ray Technicians.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
X-ray radiation is detrimental to human cells and may lead to development of life-threatening diseases. Cigarette paper and cigarette smoke contain toxic elements, whereas vitamins C and E (VCE) may have regulator effects on the elements. We investigated effects of VCE administration on X-ray-induced element changes in blood of smoker and nonsmoker X-ray technicians. Twenty technicians and 30 healthy age-matched control subjects were used in the study. Ten of the X-ray technicians and 15 of the control were smokers. Blood serum samples were taken from the control. Oral vitamins C (500 mg) and E (150 mg) were supplement...
Source: Biological Trace Element Research - September 29, 2009 Category: Biology Authors: Kayan M, Nazıroğlu M, Barak C Tags: Biol Trace Elem Res Source Type: journals

Effects of Montmorillonite on Pb Accumulation, Oxidative Stress, and DNA Damage in Tilapia (Oreochromis niloticus) Exposed to Dietary Pb.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In order to investigate the effects of montmorillonite (MMT) on reducing dietary lead (Pb) toxicity to tilapia (Oreochromis niloticus), 240 fish were randomly divided into four treatments denominated as follows: control treatment (fed with a basal diet), MMT treatment (fed with a basal diet added with 0.5% MMT), Pb treatment (fed with a basal diet added with 100 mg Pb per kilogram dry weight (dw)), and Pb + MMT treatment (fed with a basal diet added with 100 mg Pb per kilogram dw and 0.5% MMT). Changes in Pb accumulation, oxidative stress, and DNA damage in tilapia were measured after 60 days. DNA damage was assessed u...
Source: Biological Trace Element Research - September 29, 2009 Category: Biology Authors: Dai W, Fu L, Du H, Liu H, Xu Z Tags: Biol Trace Elem Res Source Type: journals

Trace Minerals Status and Antioxidant Enzymes Activities in Calves with Dermatophytosis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The aim of this study was to determine the levels of trace minerals Zn, Cu, and Se, the effect of dermatophytosis on the level of thiobarbituric acid reactive substances (TBARS) as an indicator of lipid peroxidation, the status of enzymatic and nonenzymatic antioxidants, and the relationship between the mentioned trace minerals and antioxidant defense system in calves with dermatophytosis. A total of 21 Holstein calves with clinically established diagnosis of dermatophytosis and an equal number of healthy ones were included in this study. Results showed that 81% of mycotic isolates were Trichophyton verrucosum, while 1...
Source: Biological Trace Element Research - September 23, 2009 Category: Biology Authors: Al-Qudah KM, Gharaibeh AA, Al-Shyyab MM Tags: Biol Trace Elem Res Source Type: journals

Enhancement of alpha- and beta-Galactosidase Activity in Lactobacillus reuteri by Different Metal Ions.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study shows that modified culture medium with that 0.0274% Mn(2+) can be used to promote the production for alpha- and beta-galactosidase in L. reuteri CF2-7F, which may lead to enhancement of alpha- and beta-galactosidase activity and have a good potential to be used in the food industry. PMID: 19777168 [PubMed - as supplied by publisher] (Source: Biological Trace Element Research)
Source: Biological Trace Element Research - September 23, 2009 Category: Biology Authors: Ibrahim SA, Alazzeh AY, Awaisheh SS, Song D, Shahbazi A, Abughazaleh AA Tags: Biol Trace Elem Res Source Type: journals

Metals (Hg, Pb, Cu, and Zn) Bioaccumulation in Sediment, Fish, and Human Scalp Hair: A Case Study from the City of Mersin Along the Southern Coast of Turkey.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study investigates mercury, lead, copper, and zinc concentrations in six most frequently consumed fish species (120 samples), sediments (20 samples) taken from Karaduvar Fishing Area where fish species live, and Mersin Port as a contrary region, and human scalp hair for people regularly consuming these fish species (50 samples) and non-fish-eaters (15 samples) in Mersin, Turkey. On taking living environment into account, the fish groups include pelagic species of Liza saliens, Liza aurata, and demersal species of Merluccius merluccius, Mullus barbatus, Upeneus moluccensis, and Solea solea. Total Hg (THg) was found to ...
Source: Biological Trace Element Research - September 23, 2009 Category: Biology Authors: Doğan-Sağlamtimur N, Kumbur H Tags: Biol Trace Elem Res Source Type: journals

Hypocalcemia in Pregnant Women.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The objective of this study is to estimate the prevalence of hypocalcemia and its correlation with dietary intake of calcium (DICa) and urinary calcium excretion (UCaE) in pregnant women. Healthy pregnant women (n = 543) were enrolled consecutively. DICa was calculated form dietary history. Serum calcium (SCa) and 24-h UCaE was measured. Student t test and Chi-square tests were used to compare the continuous and categorical data in women with and without hypocalcemia (SCa </= 8.7 mg/dL). Linear regression was applied for determining the independent variables for hypocalcemia. The age and gestation (mean +/- SD) were 21....
Source: Biological Trace Element Research - September 22, 2009 Category: Biology Authors: Kumar A, Agarwal K, Devi SG, Gupta RK, Batra S Tags: Biol Trace Elem Res Source Type: journals

Protective Effects of Selenium and Vitamin E Combination on Experimental Colitis in Blood Plasma and Colon of Rats.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study was carried out on three groups, namely the first (control), the second (experimental colitis group, 2 ml 5% acetic acid), and the third groups (2 ml 5% acetic acid, vitamin E (100 mg/kg body weight (bw)) plus Se (0.2 mg/kg bw)). The activities of catalase (CAT), prolidase (PRS), myeloperoxidase (MPO), total antioxidant capacity (TAC), total oxidant status (TOS), oxidative stress index (OSI), total thiol (T-SH) were determined in plasma and colon samples. Macroscopic and microscopic damages in colon were increased by AA treatment (p < 0.01 and p < 0.01, respectively), whereas they were decreased by seleniu...
Source: Biological Trace Element Research - September 22, 2009 Category: Biology Authors: Bitiren M, Karakilcik AZ, Zerin M, Ozardalı I, Selek S, Nazlıgül Y, Ozgonul A, Musa D, Uzunkoy A Tags: Biol Trace Elem Res Source Type: journals

Zinc and Copper Concentrations in Human Preterm Milk.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study determined and compared the concentrations of zinc and copper in preterm milk of mothers receiving and not receiving zinc supplementation diets. The effects of maternal supplementation on the blood levels and anthropometric parameters were evaluated. Thirty-eight mothers and their preterm infants were enrolled in the study. Eighteen mothers were given a daily supplementation of 50 mg zinc, whereas the other 20 were not. Zinc and copper levels in milk were determined at 15-day intervals, as were blood zinc levels along with anthropometric parameters. Zinc and copper contents were determined by atomic absorption s...
Source: Biological Trace Element Research - September 22, 2009 Category: Biology Authors: de Figueiredo CS, Palhares DB, Melnikov P, da Cruz Montes Moura AJ, Dos Santos SC Tags: Biol Trace Elem Res Source Type: journals

Low Serum Magnesium Levels in Elderly Subjects with Metabolic Syndrome.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, serum Mg level is diminished in elderly subjects with MetS, and hyperglycemia may play dominant role in this decrease; however, the results do not clarify whether the low serum Mg level is a consequence of hyperglycemia or is a risk factor contributing to its development. PMID: 19763407 [PubMed - as supplied by publisher] (Source: Biological Trace Element Research)
Source: Biological Trace Element Research - September 17, 2009 Category: Biology Authors: Ghasemi A, Zahediasl S, Syedmoradi L, Azizi F Tags: Biol Trace Elem Res Source Type: journals

Selenium and Vitamin E Modulates Radiation-Induced Liver Toxicity in Pregnant and Nonpregnant Rat: Effects of Colemanite and Hematite Shielding.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, selenium and vitamin E supplementations and housing by concrete with colemanite was found to offer protection against gamma-irradiation-induced liver damage and oxidative stress in rats, probably by exerting a protective effect against liver necrosis via its free radical scavenging and membrane stabilizing. Protective effects of colemanite in the liver seem to be more important than in hematite. PMID: 19763408 [PubMed - as supplied by publisher] (Source: Biological Trace Element Research)
Source: Biological Trace Element Research - September 17, 2009 Category: Biology Authors: Gençel O, Naziroglu M, Celik O, Yalman K, Bayram D Tags: Biol Trace Elem Res Source Type: journals

A Series of Novel Rare Earth Molybdotungstosilicate Heteropolyoxometalates Binding to Bovine Serum Albumin: Spectroscopic Approach.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Heteropolyoxometalate complexes have been widely applied in many fields. In this paper, the interaction between a series of novel rare earth molybdotungstosilicate heteropolyoxometalates, K(10)H(3)[Ln(SiMo(6)W(5)O(39))(2)].xH(2)O (abbr. LnW(5), Ln = Pr (x = 30), Gd (x = 29), Dy (x = 28), and Yb (x = 31)), and bovine serum albumin (BSA) was investigated by spectroscopic approach under the physiological conditions. In the mechanism discussion, it was proved that the fluorescence quenching of BSA by LnW(5) is a result of the formation of LnW(5)-BSA complex. Fluorescence quenching constants were determined using the Stern-...
Source: Biological Trace Element Research - September 16, 2009 Category: Biology Authors: Hu YJ, Ou-Yang Y, Bai AM, Zhao RM, Liu Y Tags: Biol Trace Elem Res Source Type: journals

Antioxidant Responses of Wheat Seedlings to Exogenous Selenium Supply Under Enhanced Ultraviolet-B.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The paper reports the effects of selenium (Se) supply on growth and antioxidant traits of wheat (Triticum aestivum L. cv Han NO.7086) seedlings exposed to enhanced ultraviolet-B (UV-B) stress. Antioxidant responses of seedlings were different depending on the Se concentration. Compared with the control, the lower amount used (0.5 mg Se kg(-1) soil) had no significant effect on biomass accumulation. The treatments with 1.0, 2.0, and 3.0 mg Se kg(-1) promoted biomass accumulation of wheat seedlings, and the increased amount in biomass was the most at 1.0 mg Se kg(-1) treatment. Se treatments with 1.0, 2.0, and 3.0 mg kg(...
Source: Biological Trace Element Research - September 14, 2009 Category: Biology Authors: Yao X, Chu J, Ba C Tags: Biol Trace Elem Res Source Type: journals

Effect of 3-(1H-Pyrrol-2-yl)-1H-Indazole on the Antioxidant Status of Rats.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The influence of injection periods of 3-(1H-pyrrol-2-yl)-1H-indazole regarding vitamins A, E, C, selenium (Se), malondialdehyde (MDA) levels, and glutathione peroxidase (GSH-Px) activity in rats has been investigated. The substance was given by subcutaneous injection at 20 mg/kg every other day for a total of 15 injections. At the end of the treatment, Se levels in serum were determined by fluorimetry, and those of vitamins A, E, C, and malondialdehyde in serum, liver, and kidney were determined by high-performance liquid chromatography. GSH-Px activities in erythrocytes were determined spectrophotometrically. Vitamins...
Source: Biological Trace Element Research - September 14, 2009 Category: Biology Authors: Karatas F, Coteli E, Aydin S, Servi S, Kara H Tags: Biol Trace Elem Res Source Type: journals

Effects of Parenteral Supply of Iron on RBC Parameters, Performance, and Health in Neonatal Dairy Calves.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The present study was designed to evaluate the effects of parenteral iron on red blood cell parameters, performance, and health in dairy Holstein calves. Twenty neonatal calves were equally divided at random into two groups, one of which served as controls. Care was taken to ensure homogeneity of sex, age, and general health status of the animals. The controls received a normal diet and water ad libitum, while the study animals were injected with 1 g iron as Fe-dextran 2 days after birth. A daily record was kept of the calves' weight and growth parameters. At periods of 24-48 h after birth and at 14, 28, and 42 days of...
Source: Biological Trace Element Research - September 14, 2009 Category: Biology Authors: Mohri M, Poorsina S, Sedaghat R Tags: Biol Trace Elem Res Source Type: journals