30 years of (re)productive biology a symposium honoring professor Martin M. Matzuk, MD, PhD
Biol Reprod. 2024 Apr 17:ioae051. doi: 10.1093/biolre/ioae051. Online ahead of print.NO ABSTRACTPMID:38629590 | DOI:10.1093/biolre/ioae051 (Source: Biology of Reproduction)
Source: Biology of Reproduction - April 17, 2024 Category: Reproduction Medicine Authors: T Rajendra Kumar Kathleen H Burns Wei Yan Source Type: research
Sodium oligomannate's amelioration of reproductive and metabolic phenotypes in a letrozole-induced PCOS-like mouse model depends on the gut microbiome
In conclusion, the hyperinsulinemia and hyperandrogenemia of PCOS-like mice were alleviated by GV-971 intervention, which was associated with mitigating bile acid metabolism and modulating gut microbiota.PMID:38630889 | DOI:10.1093/biolre/ioae058 (Source: Biology of Reproduction)
Source: Biology of Reproduction - April 17, 2024 Category: Reproduction Medicine Authors: Zhi Li Yan Liu Yang Wang Qingqing Cai Yuhui Wang Yixuan Bai Haiou Liu Congjian Xu Feifei Zhang Source Type: research
Trajectory of primordial follicle depletion is accelerated in obese mice in response to 7,12-dimethylbenz[a]anthracene exposure
This study indicates that obesity influences ovotoxicity caused by a genotoxicant, potentially involving accelerated primordial follicle activation and hampering normal follicular dynamics.PMID:38625059 | DOI:10.1093/biolre/ioae059 (Source: Biology of Reproduction)
Source: Biology of Reproduction - April 16, 2024 Category: Reproduction Medicine Authors: Jaspreet K Rishi Kelsey Timme Hunter E White Karl C Kerns Aileen F Keating Source Type: research
Trajectory of primordial follicle depletion is accelerated in obese mice in response to 7,12-dimethylbenz[a]anthracene exposure
This study indicates that obesity influences ovotoxicity caused by a genotoxicant, potentially involving accelerated primordial follicle activation and hampering normal follicular dynamics.PMID:38625059 | DOI:10.1093/biolre/ioae059 (Source: Biology of Reproduction)
Source: Biology of Reproduction - April 16, 2024 Category: Reproduction Medicine Authors: Jaspreet K Rishi Kelsey Timme Hunter E White Karl C Kerns Aileen F Keating Source Type: research
Shear wave elastography to assess stiffness of the human ovary and other reproductive tissues across the reproductive lifespan in health and disease †
In this study, we review the underlying principles of shear wave elastography and its current clinical uses outside the reproductive tract as well as its successful application of shear wave elastography to reproductive tissues, including the uterus and cervix. We also describe an emerging use of this technology in evaluation of human ovarian stiffness via transvaginal ultrasound. Establishing ovarian stiffness as a clinical biomarker of ovarian aging may have implications for predicting the ovarian reserve and outcomes of Assisted Reproductive Technologies as well as for the assessment of the efficacy of emerging therapeu...
Source: Biology of Reproduction - April 12, 2024 Category: Reproduction Medicine Authors: Emily J Zaniker Man Zhang Lydia Hughes Lizellen La Follette Tomiris Atazhanova Alexis Trofimchuk Elnur Babayev Francesca E Duncan Source Type: research
Shear wave elastography to assess stiffness of the human ovary and other reproductive tissues across the reproductive lifespan in health and disease †
In this study, we review the underlying principles of shear wave elastography and its current clinical uses outside the reproductive tract as well as its successful application of shear wave elastography to reproductive tissues, including the uterus and cervix. We also describe an emerging use of this technology in evaluation of human ovarian stiffness via transvaginal ultrasound. Establishing ovarian stiffness as a clinical biomarker of ovarian aging may have implications for predicting the ovarian reserve and outcomes of Assisted Reproductive Technologies as well as for the assessment of the efficacy of emerging therapeu...
Source: Biology of Reproduction - April 12, 2024 Category: Reproduction Medicine Authors: Emily J Zaniker Man Zhang Lydia Hughes Lizellen La Follette Tomiris Atazhanova Alexis Trofimchuk Elnur Babayev Francesca E Duncan Source Type: research
Shear wave elastography to assess stiffness of the human ovary and other reproductive tissues across the reproductive lifespan in health and disease †
In this study, we review the underlying principles of shear wave elastography and its current clinical uses outside the reproductive tract as well as its successful application of shear wave elastography to reproductive tissues, including the uterus and cervix. We also describe an emerging use of this technology in evaluation of human ovarian stiffness via transvaginal ultrasound. Establishing ovarian stiffness as a clinical biomarker of ovarian aging may have implications for predicting the ovarian reserve and outcomes of Assisted Reproductive Technologies as well as for the assessment of the efficacy of emerging therapeu...
Source: Biology of Reproduction - April 12, 2024 Category: Reproduction Medicine Authors: Emily J Zaniker Man Zhang Lydia Hughes Lizellen La Follette Tomiris Atazhanova Alexis Trofimchuk Elnur Babayev Francesca E Duncan Source Type: research
Machine learning to identify endometrial biomarkers predictive of pregnancy success following artificial insemination in dairy cows
The objective was to identify a set of genes whose transcript abundance is predictive of a cow's ability to become pregnant following artificial insemination (AI). Endometrial epithelial cells from the uterine body were collected for RNA sequencing using the cytobrush method from 193 first-service Holstein cows at estrus prior to AI (day 0). A group of 253 first-service cows not used for cytobrush collection were controls. There was no effect of cytobrush collection on pregnancy outcomes at day 30 or 70 or on pregnancy loss between day 30 and 70. There were 2 upregulated and 214 downregulated genes (FDR < 0.05, absolute...
Source: Biology of Reproduction - April 9, 2024 Category: Reproduction Medicine Authors: Quinn A Hoorn Maria B Rabaglino Thiago F Amaral Tatiane S Maia Fahong Yu John B Cole Peter J Hansen Source Type: research
Sertoli cells require hnRNPC to surport normal spermatogenesis and male fertility in mice
In conclusion, this study demonstrates that hnRNPC plays a critical role in SCs for maintaining the function of SCs and sustaining steady-state spermatogenesis in mice.PMID:38590182 | DOI:10.1093/biolre/ioae055 (Source: Biology of Reproduction)
Source: Biology of Reproduction - April 9, 2024 Category: Reproduction Medicine Authors: Shaomei Mo Ge Shu Congcong Cao Mingxia Wang Jie Yang Jing Ye Yaoting Gui Shuiqiao Yuan Qian Ma Source Type: research
Machine learning to identify endometrial biomarkers predictive of pregnancy success following artificial insemination in dairy cows
The objective was to identify a set of genes whose transcript abundance is predictive of a cow's ability to become pregnant following artificial insemination (AI). Endometrial epithelial cells from the uterine body were collected for RNA sequencing using the cytobrush method from 193 first-service Holstein cows at estrus prior to AI (day 0). A group of 253 first-service cows not used for cytobrush collection were controls. There was no effect of cytobrush collection on pregnancy outcomes at day 30 or 70 or on pregnancy loss between day 30 and 70. There were 2 upregulated and 214 downregulated genes (FDR < 0.05, absolute...
Source: Biology of Reproduction - April 9, 2024 Category: Reproduction Medicine Authors: Quinn A Hoorn Maria B Rabaglino Thiago F Amaral Tatiane S Maia Fahong Yu John B Cole Peter J Hansen Source Type: research
Sertoli cells require hnRNPC to surport normal spermatogenesis and male fertility in mice
In conclusion, this study demonstrates that hnRNPC plays a critical role in SCs for maintaining the function of SCs and sustaining steady-state spermatogenesis in mice.PMID:38590182 | DOI:10.1093/biolre/ioae055 (Source: Biology of Reproduction)
Source: Biology of Reproduction - April 9, 2024 Category: Reproduction Medicine Authors: Shaomei Mo Ge Shu Congcong Cao Mingxia Wang Jie Yang Jing Ye Yaoting Gui Shuiqiao Yuan Qian Ma Source Type: research
Machine learning to identify endometrial biomarkers predictive of pregnancy success following artificial insemination in dairy cows
The objective was to identify a set of genes whose transcript abundance is predictive of a cow's ability to become pregnant following artificial insemination (AI). Endometrial epithelial cells from the uterine body were collected for RNA sequencing using the cytobrush method from 193 first-service Holstein cows at estrus prior to AI (day 0). A group of 253 first-service cows not used for cytobrush collection were controls. There was no effect of cytobrush collection on pregnancy outcomes at day 30 or 70 or on pregnancy loss between day 30 and 70. There were 2 upregulated and 214 downregulated genes (FDR < 0.05, absolute...
Source: Biology of Reproduction - April 9, 2024 Category: Reproduction Medicine Authors: Quinn A Hoorn Maria B Rabaglino Thiago F Amaral Tatiane S Maia Fahong Yu John B Cole Peter J Hansen Source Type: research
Sertoli cells require hnRNPC to surport normal spermatogenesis and male fertility in mice
In conclusion, this study demonstrates that hnRNPC plays a critical role in SCs for maintaining the function of SCs and sustaining steady-state spermatogenesis in mice.PMID:38590182 | DOI:10.1093/biolre/ioae055 (Source: Biology of Reproduction)
Source: Biology of Reproduction - April 9, 2024 Category: Reproduction Medicine Authors: Shaomei Mo Ge Shu Congcong Cao Mingxia Wang Jie Yang Jing Ye Yaoting Gui Shuiqiao Yuan Qian Ma Source Type: research
Machine learning to identify endometrial biomarkers predictive of pregnancy success following artificial insemination in dairy cows
The objective was to identify a set of genes whose transcript abundance is predictive of a cow's ability to become pregnant following artificial insemination (AI). Endometrial epithelial cells from the uterine body were collected for RNA sequencing using the cytobrush method from 193 first-service Holstein cows at estrus prior to AI (day 0). A group of 253 first-service cows not used for cytobrush collection were controls. There was no effect of cytobrush collection on pregnancy outcomes at day 30 or 70 or on pregnancy loss between day 30 and 70. There were 2 upregulated and 214 downregulated genes (FDR < 0.05, absolute...
Source: Biology of Reproduction - April 9, 2024 Category: Reproduction Medicine Authors: Quinn A Hoorn Maria B Rabaglino Thiago F Amaral Tatiane S Maia Fahong Yu John B Cole Peter J Hansen Source Type: research
Sertoli cells require hnRNPC to surport normal spermatogenesis and male fertility in mice
In conclusion, this study demonstrates that hnRNPC plays a critical role in SCs for maintaining the function of SCs and sustaining steady-state spermatogenesis in mice.PMID:38590182 | DOI:10.1093/biolre/ioae055 (Source: Biology of Reproduction)
Source: Biology of Reproduction - April 9, 2024 Category: Reproduction Medicine Authors: Shaomei Mo Ge Shu Congcong Cao Mingxia Wang Jie Yang Jing Ye Yaoting Gui Shuiqiao Yuan Qian Ma Source Type: research
