The role of Matrix Metalloproteinase-2 and Galectin-3 as predictive biomarkers for all-cause mortality in patients undergoing transfemoral transcatheter aortic valve implantation
Conclusion: In patients with severe aortic stenosis undergoing transfemoral TAVI, MMP-2, and to a lesser extent Gal-3, seem to have additive value in optimizing risk prediction and streamlining decision-making.PMID:38588595 | DOI:10.1080/1354750X.2024.2341409 (Source: Biomarkers)
Source: Biomarkers - April 8, 2024 Category: Research Authors: Kerstin Piayda Julian Tim Heilemann Stanislav Keranov Luisa Schulz Mani Arsalan Christoph Liebetrau Won-Keun Kim Felix J Hofmann Pascal Bauer Sandra Voss Christian Troidl Samuel T Sossalla Christian W Hamm Holger M Nef Oliver D örr Source Type: research
The Association Between Inflammatory Biomarkers and Low Back Disorder: A Systematic Review and Meta-analysis
Conclusion: Inflammatory biomarkers play a significant role in the pathogenesis of LBD. CTX-1, IL-10 and IL-1 beta may be responsible for the decrease in back pain scores post treatment. There is a relationship between MCP-1, IL-6, IL-8 and hsCRP with clinical and functional assessments for LBD. Further studies will improve understanding of the pathogenesis of LBD and aid in targeted management strategies.PMID:38578280 | DOI:10.1080/1354750X.2024.2339285 (Source: Biomarkers)
Source: Biomarkers - April 5, 2024 Category: Research Authors: Stone Sima Xiaolong Chen Ashish D Diwan Source Type: research
Upregulation of ESPL1 is associated with poor prognostic outcomes in endometrial cancer
Conclusion: The upregulation of ESPL1 is associated with advanced disease and poor prognosis in EC patients. These findings suggest that ESPL1 has the potential to serve as a diagnostic and prognostic biomarker in EC, highlighting its significance in the management of EC patients.PMID:38568742 | DOI:10.1080/1354750X.2024.2339288 (Source: Biomarkers)
Source: Biomarkers - April 3, 2024 Category: Research Authors: Yuzhong Yang Ying Sheng Jinhua Zheng Aiyu Ma Shaohua Chen Jing Lin Xiaozhen Yang Yuanna Liang Yan Zhang Xiang Zheng Source Type: research
Exocyclic DNA adducts and oxidative stress parameters: useful tools for biomonitoring exposure to aldehydes in smokers
CONCLUSION: These results are promising, and the study is now being conducted on a larger cohort with the aim of evaluating the impact of smoking cessation programs on the evolution of adducts profile and antioxidants activities.PMID:38506499 | DOI:10.1080/1354750X.2024.2333361 (Source: Biomarkers)
Source: Biomarkers - March 20, 2024 Category: Research Authors: H éléna Alamil Marie-Lise Colsoul Natacha Heutte Marie Van Der Schueren Laurence Galanti Mathilde Lechevrel Source Type: research
Exocyclic DNA adducts and oxidative stress parameters: useful tools for biomonitoring exposure to aldehydes in smokers
This study aims to investigate the relationship between a profile of nine aldehydes-induced DNA adducts and antioxidant activities, in order to evaluate new biomarkers of systemic exposure to aldehydes. Using our previously published UPLC-MS/MS method, adducts levels were quantified in the blood DNA of 34 active smokers. The levels of antioxidant vitamins (A, C and E), coenzyme Q10, β-carotene, superoxide dismutase (SOD) and autoantibodies against oxidized low-density lipoprotein were measured. Adducts induced by tobacco smoking-related aldehydes were quantified at levels reflecting an oxidative production from lipid pero...
Source: Biomarkers - March 20, 2024 Category: Research Authors: H éléna Alamil Marie-Lise Colsoul Natacha Heutte Marie Van Der Schueren Laurence Galanti Mathilde Lechevrel Source Type: research
