Nonparametric Group Sequential Methods for Evaluating Survival Benefit from Multiple Short ‐Term Follow‐up Windows
This article is protected by copyright. All rights reserved (Source: Biometrics)
Source: Biometrics - November 20, 2018 Category: Biotechnology Authors: Meng Xia, Susan Murray, Nabihah Tayob Tags: BIOMETRIC METHODOLOGY Source Type: research

Integrative Multi ‐View Regression: Bridging Group‐Sparse and Low‐Rank Models
This article is protected by copyright. All rights reserved (Source: Biometrics)
Source: Biometrics - November 20, 2018 Category: Biotechnology Authors: Gen Li, Xiaokang Liu, Kun Chen Tags: BIOMETRIC METHODOLOGY Source Type: research

A Smoothing ‐based Goodness‐of‐Fit Test of Covariance for Functional Data
SummaryFunctional data methods are often applied to longitudinal data as they provide a more flexible way to capture dependence across repeated observations. However, there is no formal testing procedure to determine if functional methods are actually necessary. We propose a goodness ‐of‐fit test for comparing parametric covariance functions against general nonparametric alternatives for both irregularly observed longitudinal data and densely observed functional data. We consider a smoothing‐based test statistic and approximate its null distribution using a bootstrap proce dure. We focus on testing a quadratic polyno...
Source: Biometrics - November 19, 2018 Category: Biotechnology Authors: Stephanie T. Chen, Luo Xiao, Ana ‐Maria Staicu Tags: BIOMETRIC METHODOLOGY Source Type: research

A Bayesian Hidden Markov Model for Detecting Differentially Methylated Regions
This study adopts a Bayesian approach using the hidden Markov model to account for inherent dependence in read count data. Given the expense of sequencing experiments, few replicates are available for each treatment group. A Bayesian approach that borrows information across an entire chromosome improves the reliability of statistical inferences. The proposed hidden Markov model considers location dependence among genomic loci by incorporating correlation structures as a function of genomic distance. An iterative algorithm based on expectation ‐maximization is designed for parameter estimation. Methylation states are infe...
Source: Biometrics - November 15, 2018 Category: Biotechnology Authors: Tieming Ji Tags: BIOMETRIC PRACTICE Source Type: research

Exact Inference on the Random ‐Effects Model for Meta‐Analyses with Few Studies
This article is protected by copyright. All rights reserved (Source: Biometrics)
Source: Biometrics - November 14, 2018 Category: Biotechnology Authors: Haben Michael, Suzanne Thornton, Minge Xie, Lu Tian Tags: BIOMETRIC METHODOLOGY Source Type: research

The Single ‐Index/Cox Mixture Cure Model
This article is protected by copyright. All rights reserved (Source: Biometrics)
Source: Biometrics - November 14, 2018 Category: Biotechnology Authors: Ma ïlis Amico, Ingrid Van Keilegom, Catherine Legrand Tags: BIOMETRIC METHODOLOGY Source Type: research

Convex Clustering Analysis for Histogram ‐Valued Data
This article is protected by copyright. All rights reserved (Source: Biometrics)
Source: Biometrics - November 14, 2018 Category: Biotechnology Authors: Cheolwoo Park, Hosik Choi, Chris Delcher, Yanning Wang, Young Joo Yoon Tags: BIOMETRIC METHODOLOGY Source Type: research

Causal inference accounting for unobserved confounding after outcome regression and doubly robust estimation
This article is protected by copyright. All rights reserved (Source: Biometrics)
Source: Biometrics - November 14, 2018 Category: Biotechnology Authors: Minna Genb äck, Xavier de Luna Tags: BIOMETRIC METHODOLOGY Source Type: research

A robust RUV ‐testing procedure via γ‐divergence
This article is protected by copyright. All rights reserved (Source: Biometrics)
Source: Biometrics - November 14, 2018 Category: Biotechnology Authors: Hung Hung Tags: BIOMETRIC METHODOLOGY Source Type: research

Composite Kernel Machine Regression based on Likelihood Ratio Test for Joint Testing of Genetic and Gene ‐environment Interaction Effect
This article is protected by copyright. All rights reserved (Source: Biometrics)
Source: Biometrics - November 14, 2018 Category: Biotechnology Authors: Ni Zhao, Haoyu Zhang, Jennifer J. Clark, Arnab Maity, Michael C. Wu Tags: BIOMETRIC METHODOLOGY Source Type: research

A Bayesian semiparametric approach to correlated ROC surfaces with stochastic order constraints
Biometrics,Volume 0, Issue ja, -Not available-. (Source: Biometrics)
Source: Biometrics - November 3, 2018 Category: Biotechnology Authors: Zhen Chen, Beom Seuk Hwang Source Type: research

A non ‐randomized procedure for large‐scale heterogeneous multiple discrete testing based on randomized tests
Biometrics,Volume 0, Issue ja, -Not available-. (Source: Biometrics)
Source: Biometrics - November 2, 2018 Category: Biotechnology Authors: Xiaoyu Dai, Nan Lin, Daofeng Li, Ting Wang Source Type: research

Log ‐ratio Lasso: Scalable, Sparse Estimation for Log‐ratio Models
Biometrics,Volume 0, Issue ja, -Not available-. (Source: Biometrics)
Source: Biometrics - November 2, 2018 Category: Biotechnology Authors: Stephen Bates, Robert Tibshirani Source Type: research

A Hybrid Phase I ‐II/III Clinical Trial Design Allowing Dose Re‐Optimization in Phase III
Biometrics,Volume 0, Issue ja, -Not available-. (Source: Biometrics)
Source: Biometrics - October 27, 2018 Category: Biotechnology Authors: Andrew G. Chapple, Peter F. Thall Source Type: research

Bagging and Deep Learning in Optimal Individualized Treatment Rules
Biometrics,Volume 0, Issue ja, -Not available-. (Source: Biometrics)
Source: Biometrics - October 26, 2018 Category: Biotechnology Authors: Xinlei Mi, Fei Zou, Ruoqing Zhu Source Type: research