The Cluster Model of Energy Transduction in Biological Systems
Biosystems. 2024 Apr 12:105213. doi: 10.1016/j.biosystems.2024.105213. Online ahead of print.ABSTRACTThe central problem in transduction is to explain how the energy caught from sunlight by chloroplasts becomes biological work. Or to express it in different terms: how does the energy remain trapped in the biological network and not get lost through thermalization into the environment? The pathway consists of an immensely large number of steps crossing hierarchical levels - some upwards, to larger assemblies, others downwards into energy rich molecules - before fuelling an action potential or a contracting cell. Accepting t...
Source: Biosystems - April 14, 2024 Category: Biotechnology Authors: John Grant Watterson Source Type: research

Editorial: Systems Bioinformatics for Medicine
Biosystems. 2024 Apr 11:105211. doi: 10.1016/j.biosystems.2024.105211. Online ahead of print.NO ABSTRACTPMID:38614277 | DOI:10.1016/j.biosystems.2024.105211 (Source: Biosystems)
Source: Biosystems - April 13, 2024 Category: Biotechnology Authors: Yoshiyuki Asai Masahiko Nakatsui Hiroshi Matsuno Source Type: research

Editorial: Systems Bioinformatics for Medicine
Biosystems. 2024 Apr 11:105211. doi: 10.1016/j.biosystems.2024.105211. Online ahead of print.NO ABSTRACTPMID:38614277 | DOI:10.1016/j.biosystems.2024.105211 (Source: Biosystems)
Source: Biosystems - April 13, 2024 Category: Biotechnology Authors: Yoshiyuki Asai Masahiko Nakatsui Hiroshi Matsuno Source Type: research

Fractional nutrient uptake model of plant roots
Biosystems. 2024 Apr 8:105210. doi: 10.1016/j.biosystems.2024.105210. Online ahead of print.ABSTRACTMost nutrient uptake problems are modeled by the convection-diffusion equation (CDE) abiding by Fick's law. Because nutrients needed by plants exist in the soil solution as a form of ions and the soil is a typical fractal structure of heterogeneity, it makes the solute transport appear anomalous diffusion in soil. Taking anomalous diffusion as a transport process, we propose time and space fractional nutrient uptake models based on the classic Nye-Tinker-Barber model. There does not appear apparent sub-diffusion of nitrate i...
Source: Biosystems - April 10, 2024 Category: Biotechnology Authors: Yue Wang Mingfang Lin Quanbiao Gong Zhonghui Ou Source Type: research

Fractional nutrient uptake model of plant roots
Biosystems. 2024 Apr 8:105210. doi: 10.1016/j.biosystems.2024.105210. Online ahead of print.ABSTRACTMost nutrient uptake problems are modeled by the convection-diffusion equation (CDE) abiding by Fick's law. Because nutrients needed by plants exist in the soil solution as a form of ions and the soil is a typical fractal structure of heterogeneity, it makes the solute transport appear anomalous diffusion in soil. Taking anomalous diffusion as a transport process, we propose time and space fractional nutrient uptake models based on the classic Nye-Tinker-Barber model. There does not appear apparent sub-diffusion of nitrate i...
Source: Biosystems - April 10, 2024 Category: Biotechnology Authors: Yue Wang Mingfang Lin Quanbiao Gong Zhonghui Ou Source Type: research

Fractional nutrient uptake model of plant roots
Biosystems. 2024 Apr 8:105210. doi: 10.1016/j.biosystems.2024.105210. Online ahead of print.ABSTRACTMost nutrient uptake problems are modeled by the convection-diffusion equation (CDE) abiding by Fick's law. Because nutrients needed by plants exist in the soil solution as a form of ions and the soil is a typical fractal structure of heterogeneity, it makes the solute transport appear anomalous diffusion in soil. Taking anomalous diffusion as a transport process, we propose time and space fractional nutrient uptake models based on the classic Nye-Tinker-Barber model. There does not appear apparent sub-diffusion of nitrate i...
Source: Biosystems - April 10, 2024 Category: Biotechnology Authors: Yue Wang Mingfang Lin Quanbiao Gong Zhonghui Ou Source Type: research

Rapid clade divergence and phyletic gradualism in an interacting particle model of sympatric speciation
In this study, we examine a simple model that simulates the evolutionary changes occurring within populations inhabiting the same environment in sympatry, and driven by ecological competition. Our model characterizes populations through a set of evolving morphological traits represented by mathematical points within a two-dimensional morphospace. Such points may reproduce or die due to overcrowding, implying competition in morphospace as suggested by the ecological phenomenon of character displacement. By focusing on the morphospace rather than physical space, the model effectively captures the simultaneous evolution of co...
Source: Biosystems - April 4, 2024 Category: Biotechnology Authors: Fabio Vittorio De Blasio Birgitte Freiesleben De Blasio Source Type: research

Rapid clade divergence and phyletic gradualism in an interacting particle model of sympatric speciation
In this study, we examine a simple model that simulates the evolutionary changes occurring within populations inhabiting the same environment in sympatry, and driven by ecological competition. Our model characterizes populations through a set of evolving morphological traits represented by mathematical points within a two-dimensional morphospace. Such points may reproduce or die due to overcrowding, implying competition in morphospace as suggested by the ecological phenomenon of character displacement. By focusing on the morphospace rather than physical space, the model effectively captures the simultaneous evolution of co...
Source: Biosystems - April 4, 2024 Category: Biotechnology Authors: Fabio Vittorio De Blasio Birgitte Freiesleben De Blasio Source Type: research

Rapid clade divergence and phyletic gradualism in an interacting particle model of sympatric speciation
In this study, we examine a simple model that simulates the evolutionary changes occurring within populations inhabiting the same environment in sympatry, and driven by ecological competition. Our model characterizes populations through a set of evolving morphological traits represented by mathematical points within a two-dimensional morphospace. Such points may reproduce or die due to overcrowding, implying competition in morphospace as suggested by the ecological phenomenon of character displacement. By focusing on the morphospace rather than physical space, the model effectively captures the simultaneous evolution of co...
Source: Biosystems - April 4, 2024 Category: Biotechnology Authors: Fabio Vittorio De Blasio Birgitte Freiesleben De Blasio Source Type: research

Rapid clade divergence and phyletic gradualism in an interacting particle model of sympatric speciation
In this study, we examine a simple model that simulates the evolutionary changes occurring within populations inhabiting the same environment in sympatry, and driven by ecological competition. Our model characterizes populations through a set of evolving morphological traits represented by mathematical points within a two-dimensional morphospace. Such points may reproduce or die due to overcrowding, implying competition in morphospace as suggested by the ecological phenomenon of character displacement. By focusing on the morphospace rather than physical space, the model effectively captures the simultaneous evolution of co...
Source: Biosystems - April 4, 2024 Category: Biotechnology Authors: Fabio Vittorio De Blasio Birgitte Freiesleben De Blasio Source Type: research

Rapid clade divergence and phyletic gradualism in an interacting particle model of sympatric speciation
In this study, we examine a simple model that simulates the evolutionary changes occurring within populations inhabiting the same environment in sympatry, and driven by ecological competition. Our model characterizes populations through a set of evolving morphological traits represented by mathematical points within a two-dimensional morphospace. Such points may reproduce or die due to overcrowding, implying competition in morphospace as suggested by the ecological phenomenon of character displacement. By focusing on the morphospace rather than physical space, the model effectively captures the simultaneous evolution of co...
Source: Biosystems - April 4, 2024 Category: Biotechnology Authors: Fabio Vittorio De Blasio Birgitte Freiesleben De Blasio Source Type: research

An integrated approach to understand the regulatory role of miR-27 family in breast cancer metastasis
Biosystems. 2024 Mar 31;238:105200. doi: 10.1016/j.biosystems.2024.105200. Online ahead of print.ABSTRACTOne of the prime reasons of increasing breast cancer mortality is metastasizing cancer cells. Owing to the side effects of clinically available drugs to treat breast cancer metastasis, it is of utmost importance to understand the underlying biogenesis of breast cancer tumorigenesis. In-silico identification of potential RNAs might help in utilizing the miR-27 family as a therapeutic target in breast cancer. The experimentally verified common interacting mRNAs for miR27 family are retrieved from three publicly available ...
Source: Biosystems - April 2, 2024 Category: Biotechnology Authors: Sohini Chakraborty Utpalendu Paul Subhadeep Banerjee Debanjan Saha Satarupa Banerjee Source Type: research

An integrated approach to understand the regulatory role of miR-27 family in breast cancer metastasis
Biosystems. 2024 Mar 31;238:105200. doi: 10.1016/j.biosystems.2024.105200. Online ahead of print.ABSTRACTOne of the prime reasons of increasing breast cancer mortality is metastasizing cancer cells. Owing to the side effects of clinically available drugs to treat breast cancer metastasis, it is of utmost importance to understand the underlying biogenesis of breast cancer tumorigenesis. In-silico identification of potential RNAs might help in utilizing the miR-27 family as a therapeutic target in breast cancer. The experimentally verified common interacting mRNAs for miR27 family are retrieved from three publicly available ...
Source: Biosystems - April 2, 2024 Category: Biotechnology Authors: Sohini Chakraborty Utpalendu Paul Subhadeep Banerjee Debanjan Saha Satarupa Banerjee Source Type: research

An integrated approach to understand the regulatory role of miR-27 family in breast cancer metastasis
Biosystems. 2024 Mar 31:105200. doi: 10.1016/j.biosystems.2024.105200. Online ahead of print.ABSTRACTOne of the prime reasons of increasing breast cancer mortality is metastasizing cancer cells. Owing to the side effects of clinically available drugs to treat breast cancer metastasis, it is of utmost importance to understand the underlying biogenesis of breast cancer tumorigenesis. In-silico identification of potential RNAs might help in utilizing the miR-27 family as a therapeutic target in breast cancer. The experimentally verified common interacting mRNAs for miR27 family are retrieved from three publicly available data...
Source: Biosystems - April 2, 2024 Category: Biotechnology Authors: Sohini Chakraborty Utpalendu Paul Subhadeep Banerjee Debanjan Saha Satarupa Banerjee Source Type: research

The sensual cell: Feeling and affect in unicellular species
Biosystems. 2024 Mar 29:105197. doi: 10.1016/j.biosystems.2024.105197. Online ahead of print.ABSTRACTOur previous efforts to probe the complex, rich experiential lives of unicellular species have focused on the origins of consciousness (Reber, 2019) and the biomolecular processes that underlie sentience (Reber et al., 2023). Implied, but unexplored, was the assumption that these cognitive functions and associated unicellular organismal behaviors were linked with and often driven by affect, feelings, sensual experiences. In this essay we dig more deeply into these valenced (We're using the term valence here to cover the asp...
Source: Biosystems - March 31, 2024 Category: Biotechnology Authors: Arthur S Reber Franti šek Baluška William B Miller Predrag Slijep čević Source Type: research