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ZEBETA (Bisoprolol Fumarate) Tablet [Duramed Pharmaceuticals, Inc.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Updated Date: Nov 19, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - November 19, 2009 Category: Drugs & Pharmacology Source Type: organizations

Differential Effects of Oral {beta} Blockade on Cardiovascular and Sympathetic RegulationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In patients with hypertension, β blockade decreases muscle sympathetic nerve activity (MSNA; micrographic technique) expressed in burst frequency (burst/min) but does not affect MSNA expressed in burst incidence (burst/100 heart beats), because reductions in blood pressure (BP) upon each diastole continue to deactivate the arterial baroreceptors, but at a slower heart rate (HR). We studied the effects of oral β blockade on MSNA and baroreflex sensitivity (BRS) in normal participants. Bisoprolol (5 mg, 1 week) was administered in 10 healthy young adults, using a double-blind, placebo-controlled, randomized cross-o...
Source: Journal of Cardiovascular Pharmacology and Therapeutics - November 11, 2009 Category: Cardiology Authors: Beloka, S.P., Gouveia, S., Gujic, M., Naeije, R., Rocha, A.P., van de Borne, P. Tags: Articles Source Type: journals

Meta-analysis: beta-blocker dose, heart rate reduction, and death in patients with heart failureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: DARE Area: Evidence > Disease Focused Reviews CRD Summary: This review concluded that the magnitude of heart rate reduction was statistically significantly associated with the survival benefit of beta-blockers in heart failure, but the dose of beta-blocker was not. The majority of the review process and the synthesis were well conducted. Despite the absence of a validity assessment, the conclusions appear likely to be reliable. [Included studies assessed metoprolol, carvedilol, bisoprolol, bucindolol, nebivolol and atenolol. ] CRD Commentary: The review question was clear and was supported by specific inclusio...
Source: NeLM - Disease Focused Reviews - November 6, 2009 Category: Internal Medicine Source Type: organizations

Low-dose Fixed Combination of Bisoprolol/Hydrochlorothiazide as First Line for Hypertension: A Review of the Rationale and Clinical EvidenceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Essential hypertension is a heterogeneous multifactorial disease. Data from the National Health and Nutritional Examination Survey and from the World Health Organization have clearly demonstrated that, worldwide, less than 30% of hypertensive patients are adequately controlled by our currently accepted blood pressure goals. Although monotherapy is often unable to achieve blood pressure goals, the use of fixed low-dose combination drugs as alternative treatment seems to be related to a better antihypertensive efficacy and higher response rates in the low range of doses as the result of complementary mechanisms of antihypert...
Source: Angiology - October 22, 2009 Category: Cardiology Authors: Papadopoulos, D. P., Papademetriou, V. Tags: Articles Source Type: journals

Bisoprolol: First report of a fixed drug eruption: case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Reactions)
Source: Reactions - October 19, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals

Liquid chromatography tandem mass spectrometry method for determination of bisoprolol in human plasma using d5-bisoprolol as the internal standard.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A simple, reliable and sensitive liquid chromatography tandem mass spectrometry (LC-MS/MS) protocol was developed and validated for quantification of bisoprolol in human plasma. The sample was pretreated with a simple procedure of protein precipitation and an isotope-labeled d5-bisoprolol was used as internal standard. The chromatographic separation was performed on a Capcell Pak C(18) MG III column (100 mm x 2.0 mm, 5 microm). The protonated ion of the analyte was detected in positive ionization by multiple reaction monitoring mode. The mass transition pairs of m/z 326.3 --> 116.3 and m/z 331.3 --> 121.3 were us...
Source: Biomedical Chromatography : BMC - October 4, 2009 Category: Biomedical Science Authors: Liu GY, Wang W, Jia JY, Lu C, Liu YM, Zhang MQ, Liu Y, Li SJ, Yu C Tags: Biomed Chromatogr Source Type: journals

Respiratory Effects of β-blocker Therapy in Heart FailureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, it is possible to use β-blockers in HF patients even in the presence of lung function impairment, but their use should be guided by a combination of lung function evaluation and knowledge of the pharmacological properties of each molecule Content Type Journal ArticleDOI 10.1007/s10557-009-6195-2Authors Piergiuseppe Agostoni, Università di Milano Centro Cardiologico Monzino-IRCCS, Istituto di Cardiologia via Parea 4 20138 Milan ItalyPietro Palermo, Università di Milano Centro Cardiologico Monzino-IRCCS, Istituto di Cardiologia via Parea 4 20138 Milan ItalyMauro Contini, Università di Milano Centro ...
Source: Cardiovascular Drugs and Therapy - September 29, 2009 Category: Cardiology Tags: Cardiovascular Drugs and Therapy Source Type: journals

BISOPROLOL FUMARATE TABLETS (Bisoprolol Fumarate) Tablet [Unichem Pharmaceuticals (USA), Inc.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Updated Date: Sep 22, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - September 22, 2009 Category: Drugs & Pharmacology Source Type: organizations

ZIAC (Bisoprolol Fumarate And Hydrochlorothiazide) Tablet, Film Coated [Duramed Pharmaceuticals Inc.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Updated Date: Sep 11, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - September 11, 2009 Category: Drugs & Pharmacology Source Type: organizations

Interaction of beta-blockers with the renal uptake transporter OCT2Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: These in vitro results demonstrate that alterations of uptake transporter function by beta-blockers have to be considered as potential mechanisms underlying drug[ndash]drug interactions in the kidney. (Source: Diabetes, Obesity and Metabolism)
Source: Diabetes, Obesity and Metabolism - September 9, 2009 Category: Endocrinology Authors: I. Bachmakov, H. Glaeser, B. Endress, F. Mörl, J. König, M. F. Fromm Source Type: journals

bisoprolol, ZebetaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Title: bisoprolol, ZebetaCategory: MedicationsCreated: 3/26/1998 2:30:00 PMLast Editorial Review: 9/2/2009 (Source: MedicineNet Heart General)
Source: MedicineNet Heart General - September 2, 2009 Category: Cardiology Source Type: consumer

bisoprolol, ZebetaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Title: bisoprolol, ZebetaCategory: MedicationsCreated: 3/26/1998 2:30:00 PMLast Editorial Review: 9/2/2009 (Source: MedicineNet High Blood Pressure General)
Source: MedicineNet High Blood Pressure General - September 2, 2009 Category: Cardiology Source Type: consumer

bisoprolol, ZebetaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Title: bisoprolol, ZebetaCategory: MedicationsCreated: 3/26/1998 2:30:00 PMLast Editorial Review: 9/2/2009 (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - September 2, 2009 Category: Drugs & Pharmacology Source Type: consumer

bisoprolol, ZebetaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Title: bisoprolol, ZebetaCategory: MedicationsCreated: 3/26/1998 2:30:00 PMLast Editorial Review: 9/2/2009 (Source: MedicineNet Senior Health General)
Source: MedicineNet Senior Health General - September 2, 2009 Category: Geriatrics Source Type: consumer

The effectiveness of collaborative medicine reviews in delaying time to next hospitalization for patients with heart failure in the practice setting: results of a cohort study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Medicines review in the practice setting is effective in delaying time to next hospitalization for heart failure in those treated with heart failure medicines. PMID: 19808372 [PubMed - indexed for MEDLINE] (Source: Australian Family Physician)
Source: Australian Family Physician - September 1, 2009 Category: Primary Care Authors: Roughead EE, Barratt JD, Ramsay E, Pratt N, Ryan P, Peck R, Killer G, Gilbert AL Tags: Circ Heart Fail Source Type: journals

Survival among patients with left ventricular systolic dysfunction treated with atenolol.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Metoprolol succinate, carvedilol, and bisoprolol are approved for use in heart failure. Other beta-blockers have been found to be inferior (metoprolol tartrate) or have not been studied (atenolol). The authors compared all-cause mortality following treatment with either atenolol, carvedilol, or metoprolol tartrate for 974 patients with left ventricular function < or =40%. The unadjusted mortality at 6 months was lower with atenolol (3.2%) and carvedilol (4.2%) when compared with metoprolol tartrate (7.5%, P< or =.039). However, patients with atenolol were older but had less prior heart failure. After adjustment f...
Source: Congestive Heart Failure - August 31, 2009 Category: Cardiology Authors: Kapoor JR, Heidenreich PA Tags: Congest Heart Fail Source Type: journals

The effect of an evening dose of a long-acting beta-blocker on the autonomic tone in patients with congestive heart failure.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: An evening dose of a beta-blocker is more effective than a morning dose in reversing adverse changes in the autonomic nervous system activity in CHF patients. PMID: 19838952 [PubMed - as supplied by publisher] (Source: Kardiologia Polska)
Source: Kardiologia Polska - August 31, 2009 Category: Cardiology Authors: Targoński R, Sadowski J Tags: Kardiol Pol Source Type: journals

Bisoprolol: Exacerbation of psoriasis: case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Reactions)
Source: Reactions - August 24, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals

Unichem gets FDA nod to market hypertension drugEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Unichem Laboratories Ltd said it has received the US Food and Drug Administration approval to sell its anti hypertension drug, bisoprolol fumarate, tablets in 5mg and 10 mg doses. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - August 20, 2009 Category: Pharmaceuticals Source Type: news

A New Liquid Chromatography-Tandem Mass Spectrometry Method for Determination of Bisoprolol in Human Plasma SamplesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Liquid chromatography (LC) coupled with mass spectrometry (MS) detection is one of the most powerful analytical tools for organic compound analysis. The advantages of using LC/MS methods over HPLC methods include: selectivity, chromatographic integrity, peak assignment, structural information, and rapid method development. In this paper, a new liquid chromatography-tandem mass spectrometry (LC-MS/MS) method has been developed and validated for the determination of bisoprolol in human plasma samples, using metoprolol as internal standard and liquid-liquid extraction procedure. The assay has proven to be sensitive, specific ...
Source: Journal of Biomedicine and Biotechnology - August 19, 2009 Category: Biotechnology Source Type: journals

Changes in components of left ventricular mechanics under selective beta-1 blockade: insight from traditional and new technologies in echocardiographyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion In hypertensive subjects with preserved LV EF, parameters of longitudinal LV systolic mechanics may not reflect the LV myocardial contractility status in steady-state conditions under short-term treatment with β1-block. (Source: European Journal of Echocardiography)
Source: European Journal of Echocardiography - August 10, 2009 Category: Cardiology Authors: Palmieri, V., Russo, C., Palmieri, E. A., Pezzullo, S., Celentano, A. Tags: CLINICAL/ORIGINAL PAPERS Source Type: journals

One-Year Renal and Cardiac Effects of Bisoprolol versus Losartan in Recently Diagnosed Hypertensive Patients: A Randomized, Double-Blind StudyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Clinical Drug Investigation)
Source: Clinical Drug Investigation - August 10, 2009 Category: Drugs & Pharmacology Authors: Parrinello, GasparePaterna, SalvatoreTorres, DanielePietro Di Pasquale,Mezzero, ManuelaGabriella La Rocca,Cardillo, MauroTrapanese, CaterinaCaradonna, MarioLicata, Giuseppe Tags: Original Research Articles Source Type: journals

Bisoprolol/doxazosin/valsartan: Sarcoidosis to anhydrous colloidal silica excipient: case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Reactions)
Source: Reactions - July 26, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals

Clinical trials update from the European Society of Cardiology heart failure meeting 2009: CHANCE, B-Convinced, CHAT, CIBIS-ELD, and Signal-HFEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This paper provides information and a commentary on trials relevant to the pathophysiology, prevention, and treatment of heart failure presented at the annual meeting of the Heart Failure Association of the European Society of Cardiology held in Nice. The CHANCE study showed a substantial reduction in morbidity and mortality in a randomized controlled trial (RCT) of a multidisciplinary management programme for patients with chronic heart failure in Russia. Data from the B-Convinced study, also an RCT, suggest that continuation of beta-blocker (BB) therapy in patients hospitalized with worsening heart failure may be associa...
Source: European Journal of Heart Failure - July 23, 2009 Category: Cardiology Authors: Cleland, J. G.F., Coletta, A. P., Torabi, A., Clark, A. L. Tags: CLINICAL TRIALS Source Type: journals

Effects of AT1 receptor and beta1 receptor blocking on blood pressure, peripheral hemodynamic and lipid profile in statin-treated hypertensive hypercholesterolemic patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Recent evidences suggest a relationship between angiotensin 1 (AT1) receptor gene expression and low density lipoprotein cholesterol (LDL-C) plasma level. We enrolled 16 untreated hypertensive hypercholesterolemic patients (57.4 ± 7 years old) in a randomized, single-blind, cross-over design. All the patients were allocated to treatment with simvastatin 20 mg/day for 2 weeks, then randomly assigned to telmisartan (40[ndash]80 mg/day) or bisoprolol (5[ndash]10 mg/day). After 4 weeks the antihypertensive drugs have been withdrawn for a wash-out period of 2 weeks when they were treated with simvastatin alone, then they have ...
Source: Fundamental and Clinical Pharmacology - June 24, 2009 Category: Drugs & Pharmacology Authors: Arrigo F.G. Cicero, Maddalena Veronesi, Maria Grazia Prandin, Valentina Di Gregori, Ettore Ambrosioni, Claudio Borghi Source Type: journals

Bisoprolol in patients with heart failure and moderate to severe chronic obstructive pulmonary disease: a randomized controlled trialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Initiation of bisoprolol in patients with HF and concomitant moderate or severe COPD resulted in a reduction in FEV1. However, symptoms and quality of life were not impaired. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - June 23, 2009 Category: Cardiology Authors: Hawkins, N. M., MacDonald, M. R., Petrie, M. C., Chalmers, G. W., Carter, R., Dunn, F. G., McMurray, J. J.V. Tags: TREATMENT Source Type: journals

Use of a Nurse-led Intervention to Optimize Beta-blockade for Reducing Cardiac Events After Major Noncardiac SurgeryEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Does using an algorithm-based strategy for bisoprolol titration reduce cardiac events after major non-cardiac surgery? American Heart Journal (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - June 8, 2009 Category: Intensive Care Tags: Cardiology Source Type: info

Reversed-phase high-performance liquid chromatographic enantioresolution of six beta-blockers using dinitrophenyl-l-Pro-N-hydroxysuccinimide ester, N-succinimidyl-(S)-2-(6-methoxynaphth-2-yl) propionate and twelve variants of Sanger's reagent as chiral derivatizing reagents.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Twelve chiral derivatizing reagents (CDRs) were synthesized by substituting one of the fluorine atoms in 1,5-difluoro-2,4-dinitrobenzene (DFDNB) with three optically pure amines [(R)-(-)-1-cyclohexylethylamine, (+)-dehydroabietylamine and (S)-(-)-alpha,4-dimethylbenzylamine], six amino acid amides [l-Ala-NH(2), l-Phe-NH(2), l-Val-NH(2), l-Leu-NH(2), l-Met-NH(2) and d-Phg-NH(2)] and three amino acids [l-Ala, l-Val and l-Leu]. In addition, dinitrophenyl-l-Pro-N-hydroxysuccinimide ester and N-succinimidyl-(S)-2-(6-methoxynaphth-2-yl) propionate were also synthesized and used as CDR. Keeping in view the presence of an amin...
Source: Biomedical Chromatography : BMC - May 31, 2009 Category: Biomedical Science Authors: Bhushan R, Tanwar S Tags: Biomed Chromatogr Source Type: journals

Effects of Telmisartan and Bisoprolol on Blood Pressure, Peripheral Haemodynamic and Lipid Profile in Statin-Treated Hypertensive Hypercholesterolaemic PatientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: High Blood Pressure)
Source: High Blood Pressure - May 25, 2009 Category: Cardiology Authors: Veronesi, MaddalenaCicero, Arrigo F.G.Maria Grazia Prandin,Valentina Di Gregori,Ambrosioni, EttoreBorghi, Claudio Tags: Review Articles Source Type: journals

Effects of Telmisartan and Bisoprolol on Blood Pressure, Peripheral Haemodynamic and Lipid Profile in Statin-Treated Hypertensive Hypercholesterolaemic Patients.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Page: 7DOI: 10.2165/00151642-200916010-00002Authors: Veronesi, Maddalena; Cicero, Arrigo F.G.; Prandin, Maria Grazia; Di Gregori, Valentina; Ambrosioni, Ettore; Borghi, Claudio (Source: High Blood Pressure & Cardiovascular Prevention)
Source: High Blood Pressure & Cardiovascular Prevention - May 23, 2009 Category: Cardiology Tags: Abstract HTML PDF (99 K) Source Type: journals

Use of a nurse-led intervention to optimize beta-blockade for reducing cardiac events after major noncardiac surgery.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: These data confirm a persistent CE rate after major noncardiac surgery despite nurse-led dose titration of bisoprolol. Cardiac events were equivalent to a UC strategy based on DbE results. PMID: 19332211 [PubMed - in process] (Source: American Heart Journal)
Source: American Heart Journal - April 1, 2009 Category: Cardiology Authors: Marwick TH, Branagan H, Venkatesh B, Stewart S, Tags: Am Heart J Source Type: journals

Bisoprolol and carvedilol in healthy dogsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Chronic β1-adrenoceptor signaling occurs in a failing heart. The use of β-adrenoceptor blockers is beneficial in management of humans with heart failure. Second- and third-generation β-adrenoceptor blockers effects include improved systolic function, prevention of worsening systolic function, and reduced remodeling. Both β1-adrenoceptor-selective agents and third-generation pan-adrenoceptor blocking compounds are effective in prolonging survival in humans with chronic heart failure. There has been increased interest in the use of β-adrenoceptor blockers in management strategies for heart failure associated with myxoma...
Source: Advances in Small Animal Medicine and Surgery - April 1, 2009 Category: Veterinary Research Tags: Cardiology Source Type: journals

Skeletal muscle proteins oxidation in chronic right heart failure in rats: Can different beta-blockers prevent it to the same degree?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Nebivolol seems better than bisoprolol in CHF by decreasing apoptosis and cytokines induced muscle wastage, preventing fibers shift and protein oxidation. Nebivolol by stimulating NO generation may have prevented protein oxidation. It could be speculated that ROS release, pro-inflammatory cytokines production and NF-kappa-B activation may play a key role. These positive changes could produce a favorable impact on exercise capacity in man. PMID: 19289250 [PubMed - as supplied by publisher] (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - March 14, 2009 Category: Cardiology Authors: Libera LD, Ravara B, Gobbo V, Betto DD, Germinario E, Angelini A, Evangelista S, Vescovo G Tags: Int J Cardiol Source Type: journals

Nebivolol: a third-generation beta-blocker for hypertension.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Nebivolol is a cardioselective beta-blocker that has been reported to be efficacious and well tolerated for achieving BP control in patients with hypertension. Preliminary evidence suggests a potential for reduced mortality in patients with heart failure. PMID: 19393838 [PubMed - indexed for MEDLINE] (Source: Clinical Therapeutics)
Source: Clinical Therapeutics - March 1, 2009 Category: Drugs & Pharmacology Authors: Cheng JW Tags: Clin Ther Source Type: journals

Chiral separation of beta-adrenergic blockers on CelluCoat column by HPLC.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The chiral separation of 10 beta-adrenergic blockers (acebutalol, alprenolol, bufuralol, bisoprolol, celiprolol, carazolol, indenolol, metoprolol, oxprenolol and propranolol) was achieved on CelluCoat column (250mmx4.6mm, 5mum particle size). The mobile phases used were (90:10:0.2, v/v/v) and (95:5:0.2, v/v/v) combinations of n-heptane-ethanol-diethylamine, respectively. The flow rates were 0.5, 1.0 and 2.0mLmin(-1) with detection at 225nm. The capacity (k), selectivity (alpha) and resolution (R(s)) factors were 0.44-12.91, 1.12-2.19 and 1.00-9.50, respectively. The proposed supra-molecular models indicated that the ch...
Source: Talanta - February 11, 2009 Category: Chemistry Authors: Ali I, Gaitonde VD, Aboul-Enein HY, Hussain A Tags: Talanta Source Type: journals

Chiral separations of some beta-adrenergic agonists and antagonists on AmyCoat column by HPLC.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Sixteen beta-adrenergic antagonists namely acebutalol, alprenolol, atenolol, bisoprolol, bopindolol, bufurolol, carazolol, celiprolol, indenolol, metaprolol, nebivolol, oxprenolol, practolol, propranolol, tertalol, and timolol, and two beta-adrenergic agonists namely cimeterol and clenbuterol were resolved on AmyCoat (150 x 46 mm, 3 mum size of silica particle) by using (85:15:0.1, v/v/v), (90:10:0.1, v/v/v), and (95:05:0.1, v/v/v) combinations of n-heptane, ethanol, and diethylamine solvents, respectively. The flow rates used were 0.5, 1.0, 2.0, and 3.0 ml/min with detection at 225 nm. The values of capacity, separati...
Source: Chirality - February 10, 2009 Category: Molecular Biology Authors: Ali I, Saleem K, Gaitonde VD, Aboul-Enein HY, Hussain I Tags: Chirality Source Type: journals

Bisoprolol in patients with chronic heart failure undergoing noncardiac surgeryEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Aging Health , February 2009, Vol. 5, No. 1, Pages 19-27. (Source: Future Medicine: Aging Health)
Source: Future Medicine: Aging Health - February 5, 2009 Category: Geriatrics Tags: article Source Type: journals

Bisoprolol/propofol interaction: Bradycardia: case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Reactions)
Source: Reactions - February 1, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals

Bisoprolol/propofol interaction: Bradycardia: case report.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Page: 6 (Source: Reactions Weekly)
Source: Reactions Weekly - January 31, 2009 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Hemodynamic evaluation of bisoprolol after coronary artery surgery in patients with altered left ventricular functionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Summary  Bisoprolol is a new cardioselective beta1 adrenergic blocking agent without intrinsic sympathomimetic activity but with minimal effects on myocardial contractility. Bisoprolol was compared to propranolol in 24 patients after cardiac surgery for coronary artery bypass graft (CABG). Each patient had been treated preoperatively with beta-blocking agents and had a cineangiographic left ventricular ejection fraction between 35% and 55%. Patients were randomized to receive orally either 10 mg of propranolol three times a day or 5 mg of bisoprolol once a day. Both drugs resulted in a significant and similar...
Source: Cardiovascular Drugs and Therapy - January 31, 2009 Category: Cardiology Tags: Cardiovascular Drugs and Therapy Source Type: journals

Resident physician and hospital pharmacist familiarity with patient discharge medication costsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Resident physicians and hospital pharmacists are unfamiliar with what patients must pay for drug therapy once discharged. Content Type Journal ArticleCategory Research ArticleDOI 10.1007/s11096-009-9280-5Authors Kerry Wilbur, Qatar University College of Pharmacy PO Box 2713 Doha Qatar Journal Pharmacy World & ScienceOnline ISSN 1573-739XPrint ISSN 0928-1231 (Source: Pharmacy World & Science)
Source: Pharmacy World & Science - January 29, 2009 Category: Drugs & Pharmacology Tags: Pharmacy World & Science Source Type: journals

Full recovery of Takotsubo cardiomyopathy (apical ballooning) in two days.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Takotsubo cardiomyopathy (TTC) is a new clinical entity characterised by acute but rapidly reversible left ventricular systolic dysfunction. This case report demonstrates the unique finding of a complete normalization of left ventricular function in a patient with TTC in only 36 h documented by cardiac magnetic resonance imaging. To our best knowledge, this is the most rapid complete recovery of left ventricular apical ballooning reported, yet. Medical management of our patient included optimized antihypertensive therapy with intravenous administration of the alpha-1-adrenergic blocker urapidil and the ss-blocker bisop...
Source: International Journal of Cardiology - January 19, 2009 Category: Cardiology Authors: Eitel I, Lücke C, Behrendt F, Sareban M, Gutberlet M, Schuler G, Thiele H Tags: Int J Cardiol Source Type: journals

Development and validation of a simultaneous HPLC method for estimation of bisoprolol fumarate and amlodipine besylate from tabletsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Vora D N, Kadav A AIndian Journal of Pharmaceutical Sciences 2008 70(4):542-546A fast, robust and stability indicating RP-HPLC method was developed for simultaneous determination of bisoprolol fumarate and amlodipine besylate in tablets. The mobile phase was mixture of 25 mM ammonium acetate adjusted to pH 5.0 and methanol (65: 35) at 0.8 ml/min. The stationary phase was Luna C18-2 column (3 m, 50x4.6 mm ID). UV detection was performed at 230 nm. Retention time was 1.45 min and 3.91 min for bisoprolol and amlodipine, respectively. Linearity was established in the range of 8-33 µg/ml. Mean recovery was 99.1% a...
Source: Indian Journal of Pharmaceutical Sciences - December 20, 2008 Category: Drugs & Pharmacology Authors: Vora D N, Kadav A A Source Type: journals

ORIGINAL INVESTIGATION: Comparative Effectiveness of {beta}-Blockers in Elderly Patients With Heart FailureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion  In this elderly population, the comparative effectiveness of EBBBs vs non-EBBBs was similar for 1-year survival, whereas the rehospitalization rate was higher for patients receiving EBBBs. (Source: Archives of Internal Medicine)
Source: Archives of Internal Medicine - December 8, 2008 Category: Internal Medicine Authors: Kramer, J. M., Curtis, L. H., Dupree, C. S., Pelter, D., Hernandez, A., Massing, M., Anstrom, K. J. Tags: Aging/ Geriatrics, Cardiovascular System, Statistics and Research Methods, Prognosis/ Outcomes, Drug Therapy, Drug Therapy, Other, Congestive Heart Failure/ Cardiomyopathy Original Investigation Source Type: journals

Renin-Angiotensin System and alpha-Adducin Gene Polymorphisms and Their Relation to Responses to Antihypertensive Drugs: Results From the GENRES Study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
ConclusionsCommon polymorphisms of ADD1, AGT, ACE, and AGTR1 do not markedly predict BP responses to amlodipine, bisoprolol, HCT, and losartan, at least in white hypertensive men.American Journal of Hypertension 2008; doi:10.1038/ajh.2008.343American Journal of Hypertension 2008; doi:10.1038/ajh.2008.343. PMID: 19057513 [PubMed - as supplied by publisher] (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - December 4, 2008 Category: Cardiology Authors: Suonsyrjä T, Hannila-Handelberg T, Fodstad H, Donner K, Kontula K, Hiltunen TP Tags: Am J Hypertens Source Type: journals

Unusual presentation of primary toxoplasmosis infection in a kidney-transplant patient complicated by an acute left-ventricular failure.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report describes this complication. The patient presented with high-grade fever, haemolytic anaemia and haemophagocytic-syndrome-related pancytopaenia. Toxoplasma gondii diagnosis was ascertained by blood and bone-marrow PCR assays. After 6 weeks with Clindamycin plus pyrimethamine therapies and despite negativation of T. gondii blood PCR assay, the patient developed left-ventricular failure. After adding sulfamethoxazole/ trimethoprim, ramipril, digoxine, bisoprolol and spironolactone, he progressively recovered. Anti-T. gondii therapy was continued for 6 months. Four years later he received a third kidney allograft:...
Source: NDT Plus - December 1, 2008 Category: Urology & Nephrology Authors: Hébraud B, Kamar N, Borde JS, Bessières MH, Galinier M, Rostaing L Tags: NDT Plus Source Type: journals

Comparison of the pharmacokinetic properties of bisoprolol and carvedilol in healthy dogs.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions and Clinical Relevance-After oral administration, carvedilol underwent extensive first-pass metabolism and had limited bioavailability; bisoprolol had less first-pass effect and higher bioavailability. Collectively, these differences suggested that, in dogs, bisoprolol has less interindividual pharmacokinetic variability, compared with carvedilol. PMID: 19046015 [PubMed - in process] (Source: American Journal of Veterinary Research)
Source: American Journal of Veterinary Research - December 1, 2008 Category: Veterinary Research Authors: Beddies G, Fox PR, Papich MD, Kanikanti VR, Krebber R, Keene BW Tags: Am J Vet Res Source Type: journals

Trends and inequities in beta-blocker prescribing for heart failure.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Recommended beta-blocker use has risen in the UK but remains low and inequitable, with many patients still treated with beta-blockers that are not recommended in guidelines. This suggests further improvements in prescribing are still possible. PMID: 19068160 [PubMed - in process] (Source: The British Journal of General Practice)
Source: The British Journal of General Practice - December 1, 2008 Category: Primary Care Authors: Shah SM, Carey IM, Dewilde S, Richards N, Cook DG Tags: Br J Gen Pract Source Type: journals

BisoprololEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
No Abstract. (Source: Practical Diabetes International)
Source: Practical Diabetes International - October 17, 2008 Category: Endocrinology Authors: C Smith, M Fisher, G McKay Tags: Drug Notes Source Type: journals

Postoperative oral amiodarone versus oral bisoprolol as prophylaxis against atrial fibrillation after coronary artery bypass graft surgery: A prospective randomized trialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Postoperative oral bisoprolol and amiodarone are equally effective for prophylaxis of AF after CABG. Treatment with bisoprolol resulted in a trend to lower ventricular response rate in AF cases. Both regimens were well tolerated. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - August 10, 2008 Category: Cardiology Authors: Ghassan Sleilaty, Samia Madi-Jebara, Alexandre Yazigi, Fadia Haddad, Gemma Hayeck, Issam El Rassi, Ramzi Ashoush, Victor Jebara Tags: Original Articles Source Type: journals