Diagnostics of pediatric supratentorial RELA ependymomas: integration of information from histopathology, genetics, DNA methylation and imaging
AbstractEpendymoma withRELA fusion has been defined as a novel entity of the revised World Health Organization 2016 classification of tumors of the central nervous system (CNS), characterized by fusion transcripts of theRELA gene and consequent pathological activation of the NFkB pathway. These tumors represent the majority of supratentorial ependymomas in children. The validation of diagnostic tools to identify this clinically relevant ependymoma entity is essential. Here, we have used interphase fluorescentin situ hybridization (FISH) forC11orf95andRELA, immunohistochemistry (IHC) for p65 ‐RelA and the recently develop...
Source: Brain Pathology - November 28, 2018 Category: Neurology Authors: M élanie Pagès, Kristian W. Pajtler, Stéphanie Puget, David Castel, Nathalie Boddaert, Arnault Tauziède‐Espariat, Stéphanie Picot, Marie‐Anne Debily, Marcel Kool, David Capper, Christian Sainte‐Rose, Fabrice Chrétien, Stefan M. Pfi Tags: Research Article Source Type: research

Dysregulation of TDP ‐43 Intracellular Localization and Early‐Onset ALS are Associated with a TARDBP S375G Variant
This article is protected by copyright. All rights reserved. (Source: Brain Pathology)
Source: Brain Pathology - November 21, 2018 Category: Neurology Authors: Kathy Newell, Francesca Paron, Miguel Mompean, Jill Murrell, Elisa Salis, Cristiana Stuani, Gary Pattee, Maurizio Romano, Douglas Laurents, Bernardino Ghetti, Emanuele Buratti Tags: Research Article Source Type: research

Genome ‐Wide Identification of microRNAs Regulating the Human Prion Protein
This article is protected by copyright. All rights reserved. (Source: Brain Pathology)
Source: Brain Pathology - November 19, 2018 Category: Neurology Authors: Daniel Pease, Claudia Scheckel, Elke Schaper, Valeria Eckhardt, Marc Emmenegger, Ioannis Xenarios, Adriano Aguzzi Tags: Research Article Source Type: research

Oligodendroglial A ‐synucleinopathy driven neuroinflammation in multiple system atrophy
This article is protected by copyright. All rights reserved. (Source: Brain Pathology)
Source: Brain Pathology - November 16, 2018 Category: Neurology Authors: Alana Hoffmann, Benjamin Ettle, Kristina Battis, Simone Reiprich, Johannes C. M. Schlachetzki, Eliezer Masliah, Michael Wegner, Tanja Kuhlmann, Markus J. Riemenschneider, J ürgen Winkler Tags: Research Article Source Type: research

Clarity reveals a more protracted temporal course of axon swelling and disconnection than previously described following traumatic brain injury
This article is protected by copyright. All rights reserved. (Source: Brain Pathology)
Source: Brain Pathology - November 16, 2018 Category: Neurology Authors: Maura T. Weber, John D. Arena, Rui Xiao, John A. Wolf, Victoria E. Johnson Tags: Research Article Source Type: research

Clinicopathologic features of Anaplastic Myxopapillary Ependymomas
This article is protected by copyright. All rights reserved. (Source: Brain Pathology)
Source: Brain Pathology - November 12, 2018 Category: Neurology Authors: Julieann C. Lee, Nima Sharifai, Sonika Dahiya, B.K. Kleinschmidt ‐DeMasters, Marc K. Rosenblum, Gerald F. Reis, David Samuel, Aleli M. Siongco, Mariarita Santi, Phillip B. Storm, Sean P. Ferris, Andrew W. Bollen, Melike Pekmezci, David A. S Tags: Research Article Source Type: research

Regulation of glioma cell invasion by 3q26 gene products PIK3CA, SOX2 and OPA1
This article is protected by copyright. All rights reserved. (Source: Brain Pathology)
Source: Brain Pathology - November 7, 2018 Category: Neurology Authors: Thorsten Schaefer, Archana Ramadoss, Severina Leu, Lionel Tintignac, Cristobal Tostado, Andrea Bink, Christoph Sch ürch, Joelle Müller, Jonas Schärer, Giusi Moffa, Philippe Demougin, Suzette Moes, Christoph Stippich, Simona Falbo, Heike N Tags: Research Article Source Type: research

Issue Information
Brain Pathology,Volume 28, Issue 5, Page 593-594, September 2018. (Source: Brain Pathology)
Source: Brain Pathology - October 30, 2018 Category: Neurology Source Type: research

Magnetic resonance imaging correlates of neuro ‐axonal pathology in the MS spinal cord
Brain Pathology,Volume 28, Issue 5, Page 765-772, September 2018. (Source: Brain Pathology)
Source: Brain Pathology - October 30, 2018 Category: Neurology Authors: Klaus Schmierer, Marc E Miquel Source Type: research

Myelin water imaging to detect demyelination and remyelination and its validation in pathology
Brain Pathology,Volume 28, Issue 5, Page 750-764, September 2018. (Source: Brain Pathology)
Source: Brain Pathology - October 30, 2018 Category: Neurology Authors: Cornelia Laule, G.R. Wayne Moore Source Type: research

A 66 ‐year‐old woman with progressive dementia
Brain Pathology,Volume 28, Issue 5, Page 779-781, September 2018. (Source: Brain Pathology)
Source: Brain Pathology - October 30, 2018 Category: Neurology Authors: Sheng Chen, Meng ‐Sha Yao, Fei Yuan Source Type: research

Multiple Sclerosis Pathology and its Reflection by Imaging Technologies: Introduction
Brain Pathology,Volume 28, Issue 5, Page 721-722, September 2018. (Source: Brain Pathology)
Source: Brain Pathology - October 30, 2018 Category: Neurology Authors: Hans Lassmann Source Type: research

A 77 ‐year‐old man with parkinsonism and rapidly progressive dementia
Brain Pathology,Volume 28, Issue 5, Page 777-778, September 2018. (Source: Brain Pathology)
Source: Brain Pathology - October 30, 2018 Category: Neurology Authors: Henrique Soares Dutra Oliveira, Pedro Sudbrack de Oliveira, Victor Calil, Philippe Joaquim Oliveira Menezes Mac êdo, Nathalie Canedo, Luiz Felipe Rocha Vasconcellos Source Type: research

66 Year ‐Old Woman With Muscle Weakness And Respiratory Failure
Brain Pathology,Volume 28, Issue 5, Page 775-776, September 2018. (Source: Brain Pathology)
Source: Brain Pathology - October 30, 2018 Category: Neurology Authors: J Bernardo ‐Cofiño, R Gómez‐Illán, C Nicolás, A Astudillo, I Fernandez‐Vega Source Type: research

A 3 ‐Month‐Old Boy With Progressive Weakness
Brain Pathology,Volume 28, Issue 5, Page 773-774, September 2018. (Source: Brain Pathology)
Source: Brain Pathology - October 30, 2018 Category: Neurology Authors: Soo Yeon Kim, Jung Min Ko, Sun Ah Choi, Anna Cho, Jin Sook Lee, Byung Chan Lim, Ki Joong Kim, Jong ‐Hee Chae Source Type: research