5Z ‐7‐Oxozaenol attenuates cuprizone‐induced demyelination in mice through microglia polarization regulation
ConclusionThese findings suggest that inhibiting TAK1 may be an effective approach for treating demyelinating diseases. (Source: Brain and Behavior)
Source: Brain and Behavior - April 23, 2024 Category: Neurology Authors: Shiyu Chen, Siyao Liu, Yalun Huang, Shiwen Huang, Wanzhou Zhang, Huifang Xie, Lingli Lu Tags: ORIGINAL ARTICLE Source Type: research

Periodontal  disease and risk of Alzheimer's disease: A two‐sample Mendelian randomization
ConclusionsOur findings indicate that there is no causal relationship between periodontal disease and AD at the genetic level. (Source: Brain and Behavior)
Source: Brain and Behavior - April 22, 2024 Category: Neurology Authors: Conglei Hu, Hui Li, Liping Huang, Rui Wang, Zeyu Wang, Rui Ma, Bei Chang, Shiting Li, Hongcai Li, Guangwen Li Tags: ORIGINAL ARTICLE Source Type: research

Alterations of the cerebral microstructure in patients with noise ‐induced hearing loss: A diffusion tensor imaging study
ConclusionThe changes in the white matter (WM) microstructure may be related to hearing loss caused by noise exposure, and the WM structural abnormalities in patients with NIHL were mainly located in the syndesmotic fibers of the temporooccipital region, which affected the auditory and language pathways. This confirmed that the auditory pathways have abnormal structural connectivity in patients with NIHL. (Source: Brain and Behavior)
Source: Brain and Behavior - April 22, 2024 Category: Neurology Authors: Ranran Huang, Aijie Wang, Yafei Zhang, Guochao Li, Yi Lin, Xinru Ba, Xianghua Bao, Yunxin Li, Guowei Zhang Tags: ORIGINAL ARTICLE Source Type: research

The normative values of pain thresholds in healthy Taiwanese
ConclusionsWe provided the normative values of healthy male and female adults in Taiwan. This information is crucial for comparison in future pain-related studies to identify potential hypoalgesia or hyperalgesia of tested subjects. (Source: Brain and Behavior)
Source: Brain and Behavior - April 22, 2024 Category: Neurology Authors: Li ‐Ling Hope Pan, Yu‐Hsiang Ling, Kuan‐Lin Lai, Yen‐Feng Wang, Fu‐Jung Hsiao, Shih‐Pin Chen, Hung‐Yu Liu, Wei‐Ta Chen, Shuu‐Jiun Wang Tags: ORIGINAL ARTICLE Source Type: research

Visual evoked potential in generalized joint hypermobility: A case –control study
ConclusionOur study could reveal VEP changes, especially significant P100 latency in GJH patients without previous neurologic or musculoskeletal disorders. Whether these changes are due to GJH itself or are predictive of inevitable neurologic disease or visual pathway involvement, particularly Multiple Sclerosis needs further investigation with longer follow-up periods. (Source: Brain and Behavior)
Source: Brain and Behavior - April 20, 2024 Category: Neurology Authors: Leila Sadat Mohamadi Jahromi, Amin Sayyadi, Aida Askarian, Alireza Dabbaghmanesh, Sharareh Roshanzamir Tags: ORIGINAL ARTICLE Source Type: research

Study on exosomes for identifying bipolar disorder in early stage: A cross ‐sectional and validation study protocol
DiscussionExosome-derived microRNA and related proteins have potential in serving as a good medium for exploring mental disorders because it can pass through the blood-brain barrier bidirectionally and convey a large amount of information stably. Improving the early diagnosis of BD would help implement appropriate intervention strategy as early as possible and significantly reduce the burden of disease. (Source: Brain and Behavior)
Source: Brain and Behavior - April 20, 2024 Category: Neurology Authors: Yanqing Wu, Yuchao Li, Xuguang An, Jiangong Li, Chenghao Yang, Yi Wang Tags: METHOD Source Type: research

Establishment of a model to predict mortality after decompression craniotomy for traumatic brain injury
ConclusionsWe developed a risk model that has clinical significance for the early identification of patients who will still die after DC. Interestingly, we also identified a new early risk factor for TBI patients after DC, that is, preoperative mean CT value of the superior sagittal sinus (p <  .05). (Source: Brain and Behavior)
Source: Brain and Behavior - April 20, 2024 Category: Neurology Authors: Birui Wu, Juntao Zhang, Junchen Chen, Xibo Sun, Dianhui Tan Tags: ORIGINAL ARTICLE Source Type: research

Do incidental positive emotions induce more optimistic expectations of decision outcomes? An empirical study from the perspective of event ‐related potential
ConclusionOur results suggest that positive emotions increase individuals ’ psychological expectations of decision outcomes. This study provides new empirical insights to understand the influence of incidental emotions on risky decision outcome expectations. (Source: Brain and Behavior)
Source: Brain and Behavior - April 20, 2024 Category: Neurology Authors: Ruinan Zhao, Liqing Zhou Tags: DATA ARTICLE Source Type: research

Distinct brain network organizations between club players and novices under different difficulty levels
ConclusionsThe club player group illustrated significant frontal –parietal functional connectivity patterns and topological characteristics, suggesting enhanced chunking processes for improved chess performance. (Source: Brain and Behavior)
Source: Brain and Behavior - April 20, 2024 Category: Neurology Authors: Chantat Leong, Zhiying Zhao, Zhen Yuan, Bin Liu Tags: ORIGINAL ARTICLE Source Type: research

Pediatric traumatic brain injury and early age multiple sclerosis in Finland: A nationwide register ‐based cohort study
There is no evidence of an association between pediatric traumatic brain injuty (pTBI) and early-onset multiple sclerosis 20 years post-initial trauma.Hazard ratio (HR) for pTBI was 1.10 (95% CI: 0.56-1.48). AbstractObjectiveExamine the link between pediatric traumatic brain injury (pTBI) and early-onset multiple sclerosis in Finland.MethodsConducted nationwide register study (1998 −2018) with 28,750 pTBI patients (<  18) and 38,399 pediatric references with extremity fractures. Multiple sclerosis diagnoses from Finnish Social Insurance Institution. Employed Kaplan−Meier and multivariable Cox regression for probabi...
Source: Brain and Behavior - April 16, 2024 Category: Neurology Authors: Juho Laaksonen, Ville Ponkilainen, Ilari Kuitunen, Julius M öttönen, Ville M. Mattila Tags: ORIGINAL ARTICLE Source Type: research

Multicenter registry study of cerebral venous thrombosis in china (RETAIN ‐CH): Rationale and design
DiscussionResults from this study will provide evidence on the incidence, specific risk factors, symptomatic and imaging features, and clinical outcomes of CVT in China as well as indicate whether endovascular treatment is superior to medical management alone for patients with acute CVT in the real-world.Trial registrationhttp://www.clinicaltrials.gov.IdentifierNCT05448248 (Source: Brain and Behavior)
Source: Brain and Behavior - April 16, 2024 Category: Neurology Authors: Hetao Bian, Xia Wang, Lan Liu, Feng Yan, Shan Lu, Wen Hui, Chen Zhou, Jiangang Duan, Min Li, Jian Chen, Ran Meng, Lei Cao, Longde Wang, Xunming Ji Tags: REGISTERED REPORT STAGE 1 Source Type: research

Beyond sleepless nights: Unraveling the complexity of alexithymia and suicide risk among university students
ConclusionThe findings carry profound implications for suicide prevention efforts, providing valuable insights to safeguard the well-being and resilience of university students facing suicide risk challenges. (Source: Brain and Behavior)
Source: Brain and Behavior - April 16, 2024 Category: Neurology Authors: Ahmad Daghigh Tags: ORIGINAL ARTICLE Source Type: research

Correction to Herpes zoster vaccination and the risk of dementia: A systematic review and meta ‐analysis
(Source: Brain and Behavior)
Source: Brain and Behavior - April 15, 2024 Category: Neurology Tags: CORRECTION Source Type: research

Expanding deep phenotypic spectrum associated with atypical pathogenic structural variations overlapping 15q11 –q13 imprinting region
ConclusionOur deep phenotypic observations identified a spectrum of clinical features that overlap and are unique to PWS, AS, and Dup15q syndromes. Our findings establish genotype –phenotype correlation for patients impacted by variable structural variations within the 15q11–q13 region. (Source: Brain and Behavior)
Source: Brain and Behavior - April 15, 2024 Category: Neurology Authors: Rabeya Akter Mim, Anjana Soorajkumar, Noor Kosaji, Muhammad Mizanur Rahman, Shaoli Sarker, Noushad Karuvantevida, Tamannyat Binte Eshaque, Md Atikur Rahaman, Amirul Islam, Mohammod Shah Jahan Chowdhury, Nusrat Shams, K. M. Furkan Uddin, Hosnea Tags: ORIGINAL ARTICLE Source Type: research

Alterations in brain functional connectivity in patients with mild cognitive impairment: A systematic review and meta ‐analysis of functional near‐infrared spectroscopy studies
In conclusion, fNIRS effectively identified abnormalities in FC between MCI and HC, indicating disrupted FC as potential markers for the early detection of MCI. Future studies should investigate the use of task- and region-specific FC alterations as a sensitive biomarker for MCI. (Source: Brain and Behavior)
Source: Brain and Behavior - April 15, 2024 Category: Neurology Authors: Shuangyan Wang, Weijia Wang, Jinglong Chen, Xiaoqi Yu Tags: REVIEW Source Type: research