British Journal of Dermatology
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2245 records returned
Birt–Hogg–Dubé syndrome: clinical and genetic studies of 10 French families
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Conclusions We report here the largest series to date of French patients with BHDS. We noted a high prevalence of thyroid nodules and renal cysts. However, the lack of a control group does not allow assessment of whether or not such association with BHDS is fortuitous. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - November 20, 2009 Category: Dermatology Authors: N. Kluger, S. Giraud, I. Coupier, M.-F. Avril, O. Dereure, B. Guillot, S. Richard, D. Bessis Source Type: journals
Dermoscopic rainbow pattern in non-Kaposi sarcoma lesions – reply
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(Source: British Journal of Dermatology)
Source: British Journal of Dermatology - November 17, 2009 Category: Dermatology Authors: S-T. Cheng, C-L.K. Ke, C-H. Lee, C-S. Wu, G-S. Chen, S.C-S. Hu Source Type: journals
Consider underlying body dysmorphic disorder in users of melanotan
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(Source: British Journal of Dermatology)
Source: British Journal of Dermatology - November 16, 2009 Category: Dermatology Authors: A. Affleck Source Type: journals
Using 'number needed to treat' to express the magnitudes of benefit of ultraviolet B phototherapy and of antitumour necrosis factor-α therapies for psoriasis
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(Source: British Journal of Dermatology)
Source: British Journal of Dermatology - November 16, 2009 Category: Dermatology Authors: R.S. Dawe Source Type: journals
Iatrogenic melanoma. Comment on: Melanoma epidemic: a midsummer night's dream?
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(Source: British Journal of Dermatology)
Source: British Journal of Dermatology - November 16, 2009 Category: Dermatology Authors: J.I. van der Rhee, W.J. Mooi, N.A. Kukutsch, F.A. de Snoo, W. Bergman Source Type: journals
BRAF V600E mutation and the tumour suppressor IGFBP7 in atypical genital naevi
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Conclusions The prevalence of BRAF V600E in AGN suggests that ultraviolet exposure is not essential for generating the mutation. The BRAF V600E mutational status appears to be of limited diagnostic utility in distinguishing genital naevi that exhibit atypia from those that do not. Similar to oncogenic BRAF-positive common naevi without atypia, enhanced expression of the tumour suppressor IGFBP7 in oncogenic BRAF-positive AGN supports that they are biologically inert. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - November 16, 2009 Category: Dermatology Authors: L.P. Nguyen, A. Emley, N. Wajapeyee, M.R. Green, M. Mahalingam Source Type: journals
A survey of sun protection in schools in South Wales
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(Source: British Journal of Dermatology)
Source: British Journal of Dermatology - November 16, 2009 Category: Dermatology Authors: B. Grange, E.C. Veysey, M. Morris, D.L. Roberts Source Type: journals
Extensive recalcitrant Darier disease successfully treated with laser ablation
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(Source: British Journal of Dermatology)
Source: British Journal of Dermatology - November 12, 2009 Category: Dermatology Authors: V.L. Brown, S.E. Kelly, S.M. Burge, N.P.J. Walker Source Type: journals
Clinical investigation of the novel iron-chelating agent, CP94, to enhance topical photodynamic therapy of nodular basal cell carcinoma: further explanation of a dose-escalating pilot study conducted primarily to consider the safety of this pharmacological modification
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(Source: British Journal of Dermatology)
Source: British Journal of Dermatology - November 10, 2009 Category: Dermatology Authors: A. Curnow, S.M. Campbell Source Type: journals
Ustekinumab improves health-related quality of life in patients with moderate-to-severe psoriasis: results from the PHOENIX 1 trial
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Conclusions Ustekinumab improves HRQoL in patients with moderate-to-severe psoriasis. Patient-reported outcomes measured a treatment effect beyond that indicated by clinical measures. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - November 9, 2009 Category: Dermatology Authors: M. Lebwohl, K. Papp, C. Han, B. Schenkel, N. Yeilding, Y. Wang, G.G. Krueger Source Type: journals
Merocel® nasal packing with airway: a method to help secure full-thickness skin grafts on the nasal tip
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(Source: British Journal of Dermatology)
Source: British Journal of Dermatology - November 9, 2009 Category: Dermatology Authors: C. Flohr, K.K. Lee, S. Varma Source Type: journals
Molecular basis of EEC (ectrodactyly, ectodermal dysplasia, clefting) syndrome: five new mutations in the DNA-binding domain of the TP63 gene and genotype–phenotype correlation
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In this report, we present an overview of EEC syndrome, discuss the role of TP63 in embryonic development and skin homeostasis, and report five new TP63 gene mutations. We highlight the significant intra- and interfamilial phenotypic variability in affected individuals and outline the emerging paradigm for genotype[ndash]phenotype correlation in this inherited ectodermal dysplasia syndrome. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - November 9, 2009 Category: Dermatology Authors: S.E. Clements, T. Techanukul, D. Coman, J.E. Mellerio, J.A. McGrath Source Type: journals
Felodipine-induced eruptive telangiectasia following mastectomy and radiotherapy
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(Source: British Journal of Dermatology)
Source: British Journal of Dermatology - November 9, 2009 Category: Dermatology Authors: F. Al-Niaimi, C. Lyon Source Type: journals
Daily practice assessment of liver injury in patients with psoriasis on methotrexate
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(Source: British Journal of Dermatology)
Source: British Journal of Dermatology - November 9, 2009 Category: Dermatology Authors: R.J.B. Driessen, P.C.M. van de Kerkhof, E.M.G.J. de Jong Source Type: journals
Increased expression of glucocorticoid receptor β in lymphocytes of patients with severe atopic dermatitis unresponsive to topical corticosteroid
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Conclusions Expression of GR[beta] is increased during topical corticosteroid treatment in the lymphocytes of patients with AD and, in particular, glucocorticoid-insensitive AD is associated with increased expression of GR[beta]. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - November 9, 2009 Category: Dermatology Authors: P.M. Hägg, T. Hurskainen, R. Palatsi, M. Ilves, A. Oikarinen Source Type: journals
Investigation of papulopustular eruptions caused by cetuximab treatment shows altered differentiation markers and increases in inflammatory cytokines
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Conclusions The early inflammatory events (IL-1[alpha] and TNF-[alpha] expression) seen, and the lack of pEGFR in perilesional follicles, indicate that inflammatory events induced by EGFR inhibition may initiate papulopustular eruptions along with the altered differentiations. The decrease of filaggrin may contribute to the pathogenesis of the xerosis caused by cetuximab. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - November 9, 2009 Category: Dermatology Authors: S.S. Han, M. Lee, G.H. Park, S.H. Bang, Y.K. Kang, T.W. Kim, J.L. Lee, H.M. Chang, M.H. Ryu Source Type: journals
Methotrexate: a useful steroid-sparing agent in recalcitrant chronic urticaria
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Conclusions Methotrexate may be a useful treatment for steroid-dependent chronic urticaria. Functional autoantibodies do not correlate with response. The beneficial effects of methotrexate may be anti-inflammatory and immunosuppressive. It may therefore benefit chronic urticaria independently of the pathogenic mechanism, whether autoimmune or not. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - November 9, 2009 Category: Dermatology Authors: A. Perez, A. Woods, C.E.H. Grattan Source Type: journals
Cutaneous T-cell lymphoma (mycosis fungoides) relapsed with different immunological phenotype after bone marrow transplant
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(Source: British Journal of Dermatology)
Source: British Journal of Dermatology - November 9, 2009 Category: Dermatology Authors: S. Okada, Y. Nannya, S. Ota, Y. Takazawa, G. Yamamoto, K. Kumano, K. Izutsu, T. Takahashi, S. Chiba, M. Kurokawa Source Type: journals
Treatment of benign digit tip tumours by surgical excision and secondary intention healing with scar quality assessment by epidermal ridge patterns
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(Source: British Journal of Dermatology)
Source: British Journal of Dermatology - November 4, 2009 Category: Dermatology Authors: A. Sinha, D. Smith, J.A.A. Langtry Source Type: journals
Signature polymorphisms in the internal transcribed spacer region relevant for the differentiation of zoophilic and anthropophilic strains of Trichophyton interdigitale and other species of T. mentagrophytes sensu lato
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Conclusions Signature polymorphisms were observed to be useful for the differentiation of these strains and epidemiological data showed a host specificity among zoophilic strains of T. interdigitale/Arthroderma vanbreuseghemii compared with A. benhamiae as well as characteristic clinical pictures in humans when caused by zoophilic or anthropophilic strains. The delineation is relevant because it helps in determining the correct treatment and provides clues regarding the source of the infection. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - November 3, 2009 Category: Dermatology Authors: S. Heidemann, M. Monod, Y. Gräser Source Type: journals
Hydrosoluble medicated nail lacquers: in vitro drug permeation and corresponding antimycotic activity
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Conclusions Application of the CPX/sol nail lacquer allows rapid nail penetration of CPX, providing CPX levels sufficient to inhibit fungal growth for a prolonged period of time (30 h) after application of lacquer dose. CPX/sol nail lacquer appeared superior to the market reference Loceryl® in terms of both vehicle (hydroxypropyl chitosan) and active ingredient (CPX) as witnessed by its higher efficacy on all nail pathogens. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - November 3, 2009 Category: Dermatology Authors: D. Monti, L. Saccomani, P. Chetoni, S. Burgalassi, S. Senesi, E. Ghelardi, F. Mailland Source Type: journals
Expression of the carrier protein transthyretin and its receptor megalin in human skin: preliminary findings
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(Source: British Journal of Dermatology)
Source: British Journal of Dermatology - November 3, 2009 Category: Dermatology Authors: M.A. Adly Source Type: journals
Treatment of atopic eczema with oral alitretinoin
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(Source: British Journal of Dermatology)
Source: British Journal of Dermatology - November 3, 2009 Category: Dermatology Authors: M. Grahovac, S. Molin, J.C. Prinz, T. Ruzicka, A. Wollenberg Source Type: journals
Polymorphic eruption of pregnancy with bullous lesions: a previously unreported association
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(Source: British Journal of Dermatology)
Source: British Journal of Dermatology - November 3, 2009 Category: Dermatology Authors: A.C. Sherley-Dale, R.A. Carr, R. Charles-Holmes Source Type: journals
Topical sodium cromoglicate relieves allergen- and histamine-induced dermal pruritus
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Conclusions SCG is effective in reducing pruritus but has no effect on weals, supporting the proposition that, in the skin, SCG inhibits sensory C-fibre nerve activation rather than preventing mast cell degranulation. We suggest that topical SCG treatment, delivered in an appropriate vehicle, may be beneficial for symptomatic relief of pruritus in patients with cutaneous mastocytosis and other pruritic dermatoses. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - October 30, 2009 Category: Dermatology Authors: R. Vieira dos Santos, M. Magerl, P. Martus, T. Zuberbier, M.K. Church, L. Escribano, M. Maurer Source Type: journals
Unique skin changes in a case of Albright hereditary osteodystrophy caused by a rare GNAS1 mutation
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We describe a family with AHO and hormone resistance (PHP type Ia) resulting from a rare mutation in GNAS1. The proband presented with small subcutaneous calcifications in the helix of the right ear and concentrated in a sharply demarcated zone of subcutaneous and dermal hypoplasia. This abnormality has so far not been described in patients with AHO. We speculate on the mechanism of dermal hypoplasia and resistance to PTH and suggest that subcutanous or dermal hypoplasia might be another feature which can be present in patients with AHO. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - October 27, 2009 Category: Dermatology Authors: M. Klaassens, E.W. Blom, J.J.P. Schrander, C. Ris-Stalpers, A.C. Nieuwenhuijzen Kruseman, M.A.M. van Steensel, C.T.R.M. Schrander-Stumpel Source Type: journals
Intradermal injections of polyarginine-containing immunogenic antigens preferentially elicit Tc1 and Th1 activation and antitumour immunity
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Conclusions i.d. injections of rR9-containing immunogenic Ag without adjuvants simultaneously induce dual immunological effects: the induction of Tc1- and Th1-dominant immune responses, and the induction of inflammatory and CTL-mediated immune responses at the injection area by expressing Ag epitopes on MHC class I molecules as targets. This simple vaccination approach with R9-PTD-containing fusion proteins might be useful as prophylactic immunotherapy for cancer or infectious diseases. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - October 26, 2009 Category: Dermatology Authors: H. Mitsui, T. Okamoto, M. Kanzaki, T. Inozume, N. Shibagaki, S. Shimada Source Type: journals
Skin cancer: preventive photodynamic therapy in patients with face and scalp cancerization. A randomized placebo-controlled study
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Conclusions The results obtained showed that field therapy with ALA-PDT confers a significant preventive potential against the formation of new NMSCs in patients with field changes. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - October 26, 2009 Category: Dermatology Authors: Z. Apalla, E. Sotiriou, E. Chovarda, I. Lefaki, D. Devliotou-Panagiotidou, D. Ioannides Source Type: journals
Placental hypoxia and neonatal haemangioma: clinical and histological observations
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(Source: British Journal of Dermatology)
Source: British Journal of Dermatology - October 26, 2009 Category: Dermatology Authors: V. Colonna, L. Resta*, A. Napoli, E. Bonifazi Source Type: journals
Facilitating closure of surgical defects on the lower legs with a simple knee-bend
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(Source: British Journal of Dermatology)
Source: British Journal of Dermatology - October 26, 2009 Category: Dermatology Authors: W. Hussain, N.J. Mortimer, P.J.M. Salmon Source Type: journals
Modification of the Cutaneous Dermatomyositis Disease Area and Severity Index, an outcome instrument
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Conclusions The modified CDASI is perfectly correlated with the original CDASI. It has equally good concurrent validity with the PGM-overall skin and PGM-activity scales. The CDASI subscores have equally good concurrent validity with the PGM-activity and PGM-damage scales. We suggest that PGMs of skin disease activity and damage should be assessed separately for greater specificity. The modified CDASI is a refined and equally as useful outcome measure. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - October 26, 2009 Category: Dermatology Authors: M. Yassaee, D. Fiorentino, J. Okawa, L. Taylor, C. Coley, A.B. Troxel, V.P. Werth Source Type: journals
Keratin 16 expression in epidermal melanocytes
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(Source: British Journal of Dermatology)
Source: British Journal of Dermatology - October 26, 2009 Category: Dermatology Authors: J. Bhawan, K. Whren, I. Panova, M. Yaar Source Type: journals
The 'crossover' tip-stitch in O-T flap repair
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(Source: British Journal of Dermatology)
Source: British Journal of Dermatology - October 26, 2009 Category: Dermatology Authors: W. Hussain, P.J.M. Salmon, N.J. Mortimer Source Type: journals
Rhabdomyomatous mesenchymal hamartoma resembling scleroderma 'en coup de sabre': a case report and literature review
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(Source: British Journal of Dermatology)
Source: British Journal of Dermatology - October 26, 2009 Category: Dermatology Authors: E.A.M. Ball, E.J. McGrath, H. Chong, A.L.H. Moss Source Type: journals
Genotype–phenotype correlations with TGM1: clustering of mutations in the bathing suit ichthyosis and self-healing collodion baby variants of lamellar ichthyosis
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(Source: British Journal of Dermatology)
Source: British Journal of Dermatology - October 26, 2009 Category: Dermatology Authors: B.C. Hackett, D. Fitzgerald, R.M. Watson, F.A. Hol, A.D. Irvine Source Type: journals
Association analysis of filaggrin gene mutations and atopic dermatitis in Northern China
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(Source: British Journal of Dermatology)
Source: British Journal of Dermatology - October 26, 2009 Category: Dermatology Authors: L. Ma, L. Zhang, Z-H. Di, L-P. Zhao, Y-N. Lu, J. Xu, H-D. Chen, X-H. Gao Source Type: journals
Repeated low-dose skin exposure is an effective sensitizing stimulus, a factor to be taken into account in predicting sensitization risk
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Conclusions The same degree of sensitization was induced by three exposures to DNCB 10 [mu]g cm[minus]2 as by one exposure to 60 [mu]g cm[minus]2 of DNCB. Thus repeated exposure to low doses of contact sensitizers may increase the sensitizing potency. This must be taken into account in future risk assessments. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - October 23, 2009 Category: Dermatology Authors: P. Paramasivan, C. Lai, C. Pickard, M. Ardern-Jones, E. Healy, P.S. Friedmann Source Type: journals
Late-onset of IgE sensitization to microbial allergens in young children with atopic dermatitis
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Conclusion IgE sensitization to microbial allergens is associated with an older age group in young children with mild to moderate AD. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - October 22, 2009 Category: Dermatology Authors: P.Y. Ong, R.M. Ferdman, J.A. Church Source Type: journals
Acceleration of permeability barrier recovery by exposure of skin to 10–30 kHz sound
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Conclusions These results suggest that epidermal keratinocytes might be influenced by ultrasound in a manner that results in modulation of epidermal permeability barrier homeostasis. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - October 21, 2009 Category: Dermatology Authors: M. Denda, M. Nakatani Source Type: journals
Stratum corneum integrity as a predictor for peristomal skin problems in ostomates
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Conclusion Successive tape stripping, a situation analogous to the normal use of a pouching system, caused a higher degree of barrier damage more rapidly in patients with PSP, indicating an impaired mechanical quality of the barrier. The SLS exposure test suggested a generally increased susceptibility to irritant dermatitis as assessed by TEWL. Our findings suggest tape stripping and SLS testing may have a role as predictive tests to identify patients at risk of PSP. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - October 7, 2009 Category: Dermatology Authors: H. Nybaek, S. Lophagen, T. Karlsmark, D. Bang Knudsen, G.B.E. Jemec Source Type: journals
Human eyelash characterization
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Conclusions The eyelash is structurally very close to curly hair but some biological processes related to follicle cycle and pigmentation differ markedly. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - October 5, 2009 Category: Dermatology Authors: S. Thibaut, E. De Becker, L. Caisey, D. Baras, S. Karatas, O. Jammayrac, P.J. Pisella, B.A. Bernard Source Type: journals
Extremely low frequency electromagnetic fields modulate expression of inducible nitric oxide synthase, endothelial nitric oxide synthase and cyclooxygenase-2 in the human keratinocyte cell line HaCat: potential therapeutic effects in wound heali
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Conclusions Mediators of inflammation, such as reactive nitrogen and PGE2, and keratinocyte proliferation are critical for the tissue regenerative processes. The ability of ELF-EMF to upmodulate NOS activities, thus nitrogen intermediates, as well as cell proliferation, and to downregulate COX-2 expression and the downstream intermediate PGE2, highlights the potential therapeutic role of ELF-EMF in wound healing processes. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - October 3, 2009 Category: Dermatology Authors: A. Patruno, P. Amerio, M. Pesce, G. Vianale, S. Di Luzio, A. Tulli, S. Franceschelli, A. Grilli, R. Muraro, M. Reale Source Type: journals
Trends of skin diseases in organ-transplant recipients transplanted between 1966 and 2006: a cohort study with follow-up between 1994 and 2006
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Conclusions This study gives a systematic overview of the high burden of skin diseases in OTRs. The relative distributions of skin diseases importantly changed with time after transplantation, with squamous cell carcinoma contributing most to the increasing burden of skin diseases with increasing time after transplantation. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - October 3, 2009 Category: Dermatology Authors: H.C. Wisgerhof, J.R.J. Edelbroek, J.W. de Fijter, M.C.W. Feltkamp, R. Willemze, J.N. Bouwes Bavinck Source Type: journals
Granulocyte-macrophage colony-stimulating factor enhances wound healing in diabetes via upregulation of proinflammatory cytokines
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Conclusions Our results provide useful guidelines for the clinical management of chronic ulceration in diabetes. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - October 3, 2009 Category: Dermatology Authors: Y. Fang, J. Shen, M. Yao, K.W. Beagley, B.D. Hambly, S. Bao Source Type: journals
Swine pericardium as dermal substrate for human keratinocyte culture
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Conclusions The results indicate that swine pericardium is a better substrate than allogeneic dermis for keratinocyte cultures in submerged but not in air[ndash]liquid interface cultures. Swine pericardium as a substrate opens one more possibility for skin restoration after trauma or burns. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - October 1, 2009 Category: Dermatology Authors: R. Oliveira-Prado, I.R. Caldas, G.M.V. Pereira, M.V. Andrade, J.R. Cunha-Melo Source Type: journals
Distribution of T serotypes of group A streptococci isolates from cellulitis lesions
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(Source: British Journal of Dermatology)
Source: British Journal of Dermatology - September 30, 2009 Category: Dermatology Authors: K. Hayakawa, M. Kurata, A. Okazaki, M. Okazaki, M. Endo, T. Shiohara Source Type: journals
Possible benefit of oral alitretinoin in T-lymphoproliferative diseases: a report of two patients with palmoplantar hyperkeratotic-rhagadiform skin changes and mycosis fungoides or Sézary syndrome
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(Source: British Journal of Dermatology)
Source: British Journal of Dermatology - September 28, 2009 Category: Dermatology Authors: S. Molin, T. Ruzicka Source Type: journals
Results and relevance of critical temperature threshold testing in patients with acquired cold urticaria
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Conclusions These findings indicate that temperature threshold measurements may be used for assessing disease severity and activity as well as the efficacy of therapeutic measures including novel treatment approaches for cold urticaria. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - September 27, 2009 Category: Dermatology Authors: A. Młynek, M. Magerl, F. Siebenhaar, K. Weller, R. Vieira dos Santos, T. Zuberbier, A. Zalewska-Janowska, M. Maurer Source Type: journals
An overview of skin scores used for quantifying hand eczema: a critical update according to the criteria of evidence-based medicine
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The present review gives an overview of the enormous variety of skin scores used for assessing severity in patients suffering from hand eczema. In order to evaluate the validity and practical relevance of different scoring systems according to the criteria of evidence-based medicine, in May 2009 we performed a systematic search of the literature using PubMed and the Cochrane Library. A total of 69 articles reporting on 45 different methods for quantifying hand eczema were identified. The panel of methods varied from pure subjective categories to more or less quantitative scoring systems. Furthermore, by focusing on skin sc...
Source: British Journal of Dermatology - September 27, 2009 Category: Dermatology Authors: W. Weistenhöfer, T. Baumeister, H. Drexler, B. Kütting Source Type: journals
Socioeconomic disability in psoriasis
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(Source: British Journal of Dermatology)
Source: British Journal of Dermatology - September 27, 2009 Category: Dermatology Authors: E.M. Seidler, A.B. Kimball Source Type: journals
