Laser speckle contrast imaging enables perfusion monitoring of the anterior segment during strabismus surgery: a study on the horizontal rectus muscles
Conclusion
This is the first study showing that perfusion of the anterior segment can be monitored non-invasively with LSCI during strabismus surgery. In this cohort, two horizontal rectus muscles were detached with only a small decrease in the anterior segment circulation. Future studies are required for complete mapping of the effect of surgery on multiple ocular muscles on the anterior segment circulation. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - October 20, 2023 Category: Opthalmology Authors: Engqvist, L., Sheikh, R., Albinsson, J., Blohme, J., Lindstedt, S., Dahlstrand, U. Tags: Original articles - Clinical science Source Type: research
Occult anterior uveal melanomas presenting as extrascleral extension
Conclusion
Extrascleral uveal melanoma extension can occur with undetectable, occult intraocular tumours. In these cases, plaque radiation effectively induced local tumour control, preserved vision and prevented metastasis. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - October 20, 2023 Category: Opthalmology Authors: Maheshwari, A., Finger, P. T., Iacob, C. E. Tags: Open access Original articles - Clinical science Source Type: research
Persistent subfoveal fluid in pneumatic retinopexy versus pars plana vitrectomy for rhegmatogenous retinal detachment: posthoc analysis of the PIVOT randomised trial
Conclusions
There was no significant difference in the incidence of PSFF in eyes undergoing PnR versus PPV for RRD. The presence of PSFF at 1–2 months postoperatively was associated with worse ETDRS letter score at 3 months, but there was no difference at 1 year.
Trial registration number
NCT01639209. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - October 20, 2023 Category: Opthalmology Authors: Bansal, A., Lee, W. W., Sarraf, D., Sadda, S. R., Berger, A. R., Wong, D. T., Kertes, P. J., Kohly, R. P., Hillier, R. J., Muni, R. H. Tags: Original articles - Clinical science Source Type: research
Risks of posterior segment ocular ischaemic events in patients with systemic lupus erythematosus: a population-based cohort study in Taiwan
Conclusions
SLE increases the risk of developing OIE. Systemic comorbidities and higher dosage of steroid in patients with SLE are associated with severe ocular ischaemic complications. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - October 20, 2023 Category: Opthalmology Authors: Chiou, Y.-R., Chang, Y.-S., Su, C.-F., Li, T.-H., Lai, C.-C., Hwang, D.-K., Wu, F.-Y., Chang, Y.-F. Tags: Original articles - Clinical science Source Type: research
Biphasic change in retinal nerve fibre layer thickness from 30 to 60 weeks postmenstrual age in preterm infants
Conclusion
We demonstrate the feasibility of monitoring RNFL and GCL+IPL thickness from OCT during the postnatal weeks of preterm infants. Thicknesses follow a biphasic model with a transition age at 37.8 and 39.5 weeks PMA, respectively. These findings may shed light on optic nerve development in preterm infants and assist future study designs. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - October 20, 2023 Category: Opthalmology Authors: Shen, L. L., Mangalesh, S., McGeehan, B., Seely, K. R., Tai, V., Sarin, N., Finkle, J., Winter, K. P., Tran-Viet, D., Freedman, S. F., El-Dairi, M. A., Ying, G.-S., Toth, C. A. Tags: Original articles - Clinical science Source Type: research
In vivo assessment of associations between photoreceptors structure and macular perfusion in type 1 diabetes
Conclusions
Our results demonstrated the relationship between macular perfusion at both retinal and choroidal levels and the cone mosaic in patients with DM1 interpolating swept-source-OCTA and AO metrics. In NPDR eyes, the photoreceptor damage was accompanied by CC insufficiency since the early stages of the disease. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - October 20, 2023 Category: Opthalmology Authors: Viggiano, P., Costanzo, E., Giannini, D., Fragiotta, S., De Geronimo, D., Giorno, P., Picconi, F., Frontoni, S., Varano, M., Parravano, M. Tags: Original articles - Clinical science Source Type: research
Parapapillary gamma zone associated with increased peripapillary scleral bowing: the Beijing Eye Study 2011
Conclusions
A more backward bowing of the PPS was linearly and spatially associated with the presence, size and extent of gamma zone. It suggested that the BM and the sclera were closely related in participating the biomechanical behaviour of the ONH. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - October 20, 2023 Category: Opthalmology Authors: Xue, C. C., Wang, X., Han, Y. X., Zhang, Q., Zhang, C., Wang, Y. X., Jonas, J. B. Tags: Open access Original articles - Clinical science Source Type: research
Smoking and progressive retinal nerve fibre layer thinning in glaucoma
Conclusions
Smoking intensity is associated with faster rates of RNFL thinning. Evaluation of smoking intensity might add information to the assessment of risk of glaucoma progression. Future studies are required to explore if withdrawing smoking as a modifiable risk factor can decrease progression in patients with glaucoma. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - October 20, 2023 Category: Opthalmology Authors: Nishida, T., Mahmoudinezhad, G., Weinreb, R. N., Baxter, S. L., Eslani, M., Liebmann, J. M., Girkin, C. A., Fazio, M. A., M Zangwill, L., Moghimi, S. Tags: Original articles - Clinical science Source Type: research
Association of macular OCT and OCTA parameters with visual acuity in glaucoma
Conclusions
Some macular OCT/OCTA parameters were associated with VA in moderate-advanced, but not early glaucoma. These structural parameters may help identify glaucoma patients with impaired vision and reduced quality of life.
Trial registration number
NCT00221897. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - October 20, 2023 Category: Opthalmology Authors: Wu, J.-H., Moghimi, S., Nishida, T., Mohammadzadeh, V., Kamalipour, A., Zangwill, L. M., Weinreb, R. N. Tags: Original articles - Clinical science Source Type: research
Clinical usefulness of layer-by-layer deviation maps of Spectralis OCT: comparison with Cirrus OCT
Conclusions
The Spectralis and Cirrus OCT deviation maps showed good diagnostic abilities except for the IPL layer of Spectralis. In the clinical setting, both Spectralis and Cirrus OCT can be useful for detection of RNFL defects in PPG and EG eyes. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - October 20, 2023 Category: Opthalmology Authors: Choe, S., Jang, M., Kim, Y. K., Park, K. H., Jeoung, J. W. Tags: Original articles - Clinical science Source Type: research
Choriocapillaris and progressive ganglion cell-inner plexiform layer loss in non-glaucomatous eyes
Conclusions
This is the first time to show that CC FD% and GCIPL thickness were correlated in both cross-sectional and longitudinal studies of non-glaucomatous individuals, which may potentially provide further insights on the role of CC perfusion in glaucoma development and progression. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - October 20, 2023 Category: Opthalmology Authors: Cheng, W., Wang, W., Song, Y., Lin, F., Duan, Y., Xie, L., Jin, K., Weinreb, R. N., Zhang, X. Tags: Original articles - Clinical science Source Type: research
Ancillary PanoMap OCT shows the progression of glaucomatous papillomacular bundle defect with disc haemorrhage on the fovea-disc axis
Conclusion
Most FoDi-DH cases were related to the presence and progression of glaucomatous PMB defects at locations spatially overlapping the defect. OCT helped clarify changes in PMB defects detected by red-free photograph and the detection of photo-negative PMB defects as well. Similar to inferotemporal and superotemporal-direction DH, temporal DH on the PMB may be an indicator of ongoing RNFL damage that deserves close attention. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - October 20, 2023 Category: Opthalmology Authors: Lee, E. J., Han, J. C., Kee, C. Tags: Original articles - Clinical science Source Type: research
Association of baseline optical coherence tomography angiography with the development of glaucomatous visual field defects in preperimetric glaucoma eyes
Conclusion
In PPG eyes, a lower baseline inferior temporal cpVD is significantly associated with glaucomatous VF defect development and a faster rate of global VF loss. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - October 20, 2023 Category: Opthalmology Authors: Lee, J. Y., Shin, J. W., Lee, A., Baek, M. S., Kook, M. S. Tags: Original articles - Clinical science Source Type: research
Blinking and normal ocular surface in school-aged children and the effects of age and screen time
Conclusions
Blinking characterised in situ was not impacted by age or habitual digital device use. A faster blink rate was associated with greater tear volume but not symptoms. Improved tear function was found with age suggesting that the ocular surface continues to develop through childhood. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - October 20, 2023 Category: Opthalmology Authors: Chidi-Egboka, N. C., Jalbert, I., Wagner, P., Golebiowski, B. Tags: Original articles - Clinical science Source Type: research
Relationship between dry eye symptoms and quality of life: associations and mediation analysis
Conclusion
Dry eye symptoms were independently associated with poor HRQoL. Moreover, this was partly mediated by reduced visual functioning and experiencing recent falls. Our results suggest that efforts to reduce severity of dry eye symptoms are essential to optimise patients’ overall functioning and well-being. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - October 20, 2023 Category: Opthalmology Authors: Lim, E. W. L., Chong, C. C. Y., Nusinovici, S., Fenwick, E., Lamoureux, E. L., Sabanayagam, C., Cheng, C.-Y., Tong, L. Tags: Original articles - Clinical science Source Type: research
