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My family’s story: surviving swine fluEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Thanks to H1N1, Halloween came on November 15 for the Lord and Ladies of the Cyr household My wife, Sara, and I are the proud parents of newly minted 4-year-old triplets, and this fall we just haven’t been able to get healthy in our house. We get over one illness and another one crops up a week later. Fevers come and go. Coughs are incessant. Headaches bloom and recede. It’s been never-ending. So none of us was feeling particularly well on the Thursday before Halloween when Sara called me at work and told me she had spiked a fever. We weren’t sure it was H1N1, but working in the Public Affairs Department here at Ch...
Source: Thrive, Children's Hospital Boston - November 20, 2009 Category: Pediatrics Authors: Matt Cyr Tags: H1N1 (swine flu) One parent's story Flu vaccine seasonal flu swine flu vaccine Vaccines Source Type: organizations

U-M Opens New Research Studies For Emphysema & Other COPDEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Why do some smokers develop lung disease and others don't? And just how effective is supplemental oxygen therapy in treating patients with emphysema? The University of Michigan Health System will try to find out, through two new multi-center research studies that seek to improve diagnosis and treatment for millions of people affected by emphysema, chronic bronchitis and other lung diseases. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 20, 2009 Category: Consumer Health News Tags: Respiratory / Asthma Source Type: news

U-M Opens New Research Studies For Emphysema & Other COPDEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Why do some smokers develop lung disease and others don't? And just how effective is supplemental oxygen therapy in treating patients with emphysema? The University of Michigan Health System will try to find out, through two new multi-center research studies that seek to improve diagnosis and treatment for millions of people affected by emphysema, chronic bronchitis and other lung diseases. Together, those conditions are known as chronic obstructive pulmonary disease (COPD). (Source: Asthma / Respiratory News From Medical News Today)
Source: Asthma / Respiratory News From Medical News Today - November 20, 2009 Category: Respiratory Medicine Tags: Respiratory / Asthma Source Type: news

Gaining a better picture of lung diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(University of Western Ontario) Chronic obstructive pulmonary disease (COPD), a respiratory disease commonly known as chronic bronchitis or emphysema, is the fourth leading cause of death worldwide. 600 million people live with COPD and while researchers have yet to find any real treatment or cure, Grace Parraga of Robarts Research Institute at The University of Western Ontario in London, Canada, is using various imaging techniques to gain new insight into the disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 20, 2009 Category: Global & Universal Source Type: news

Cold-related respiratory symptoms in the general populationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Cold-related respiratory symptoms are common in patients with chronic respiratory diseases, but they start to emerge at relatively low temperatures. In a cold climate, the cold-related symptoms may have an impact on the health-related quality of life. Please cite this paper as: Harju T, Mäkinen T, Näyhä S, Laatikainen T, Jousilahti P and Hassi J. Cold-related respiratory symptoms in the general population. The Clinical Respiratory Journal 2009; DOI:10.1111/j.1752-699X.2009.00172.x. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - November 20, 2009 Category: Respiratory Medicine Authors: Terttu Harju, Tiina Mäkinen, Simo Näyhä, Tiina Laatikainen, Pekka Jousilahti, Juhani Hassi Source Type: journals

Strength training can help people with lung diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
NEW YORK (Reuters Health) - People with chronic lung disease like emphysema or bronchitis can strengthen their arms and legs with resistance training, and this strength may help them perform everyday tasks more easily, a new review of 18 studies confirms. (Source: Reuters: Health)
Source: Reuters: Health - November 18, 2009 Category: Consumer Health News Tags: healthNews Source Type: news

Newly Reported Respiratory Symptoms and Conditions Among Military Personnel Deployed to Iraq and Afghanistan: A Prospective Population-based StudyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Concerns about respiratory conditions have surfaced among persons deployed to Iraq and Afghanistan. Data on 46,077 Millennium Cohort Study participants who completed baseline (July 2001–June 2003) and follow-up (June 2004–February 2006) questionnaires were used to investigate 1) respiratory symptoms (persistent or recurring cough or shortness of breath), 2) chronic bronchitis or emphysema, and 3) asthma. Deployers had a higher rate of newly reported respiratory symptoms than nondeployers (14% vs. 10%), while similar rates of chronic bronchitis or emphysema (1% vs. 1%) and asthma (1% vs. 1%) were observed. Deplo...
Source: American Journal of Epidemiology - November 18, 2009 Category: Epidemiology Authors: Smith, B., Wong, C. A., Smith, T. C., Boyko, E. J., Gackstetter, G. D., Margaret A. K. Ryan for the Millennium Cohort Study Team Tags: RESEARCH-ARTICLE Source Type: journals

Ca(V)1.2 channelopathies: from arrhythmias to autism, bipolar disorder, and immunodeficiency.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Mutations of human Ca(V)1.2 channel gene were identified only recently. The gain-of-function mutations were found at two mutually exclusive exons in patients with Timothy syndrome (TS). These patients exhibit prolonged QT interval and lethal cardiac arrhythmias. In contrast, the loss-of-function mutations of Ca(V)1.2 channel in patients with Brugada syndrome produce short QT interval that could result in sudden cardiac death. TS patients also suffer from multi-organ dysfunction that includes neurological disorder such as autism and mental retardation reflecting the wide tissue distribution of Ca(V)1.2 channel. Mutation...
Source: Pflugers Archiv : European Journal of Physiology - November 15, 2009 Category: Physiology Authors: Liao P, Soong TW Tags: Pflugers Arch Source Type: journals

Trauma, Posttraumatic Stress Disorder, and Physical Illness: Findings from the General PopulationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Our findings suggest a strong association between PTSD and cardiovascular and pulmonary diseases. Particular diagnostic and treatment attention should be paid to physical illness in PTSD positive patients in primary care, medical, and mental health settings. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - November 13, 2009 Category: Psychiatry & Psychology Authors: Spitzer, C., Barnow, S., Volzke, H., John, U., Freyberger, H. J., Grabe, H. J. Tags: PTSD, Pulmonary, Other Cardiovascular Medicine ORIGINAL ARTICLES Source Type: journals

Integration of traditional Japanese medicine in Japan—A survey on the use of Kampo among patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Preliminary analysis shows that Kampo is often used by patients in Japan; also by patients visiting a conventional clinic. For most diseases patients suggest a combination of Kampo and conventional treatment. (Source: European Journal of Integrative Medicine)
Source: European Journal of Integrative Medicine - November 13, 2009 Category: Complementary Medicine Authors: L. Hottenbacher, T. Seki, K. Watanabe, C. Witt Source Type: journals

The treatment of children with anthroposophic medicine in daily primary care—Results of a network studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study aims to investigate this field of AM.Methods: A total of 38 primary care physicians in Germany participated in this prospective, multicentre observational study. Prescriptions, diagnoses, and non-pharmacological therapies were reported for each consecutive patient. Multiple logistic regression was used to determine factors associated with anthroposophic prescriptions.Results: During the 1-year study period (year 2005), a total of 107,903 prescriptions for 18,440 children under 12 years (48.1% female) were included. The most frequent single diagnoses were acute upper respiratory tract infections (URTI) (22.7%), b...
Source: European Journal of Integrative Medicine - November 13, 2009 Category: Complementary Medicine Authors: E. Jeschke, T. Ostermann, M. Tabali, A. Bockelbrink, C. Witt, S.N. Willich, H. Matthes Source Type: journals

Mom Flies Over the Cuckoo’s NestEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Several weeks ago my mother, in her eighth or ninth year of Alzheimer’s Disease, and 63rd year of marriage, began wielding knives and trying to stab people, verbally threatening to kill my father, throwing dangerous glass objects and screaming bloody murder at her own image in the mirror—“I DON’T WANT YOU HERE, GET OUT!!!” My brother and I finally intervened and had her temporarily hospitalized in a psychiatric ward, hoping we could buy more time for her at home through stabilizing her on the right meds, and getting Dad more help. We chose a modern, upscale hospital in a New Jer...
Source: Psychology Today Food and Diet Center - November 7, 2009 Category: Nutrition Authors: Eliezer Sobel Tags: Aging Anxiety Cognition Depression Diet Happiness Health Memory Neuroscience Personality Psychiatry Resilience Stress admittance ativan bruises catheter geriatric psychiatrist glass objects health care system heat o Source Type: consumer

Wood Fires Can Harm the Youngest LungsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Exposed infants more susceptible to bronchiolitis, study finds Source: HealthDay Related MedlinePlus Topics: Bronchitis, Indoor Air Pollution, Infant and Toddler Health (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - November 6, 2009 Category: Consumer Health News Source Type: consumer

Usefulness of basophil activation test in diagnosis of occupational nonasthmatic eosinophilic bronchitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Allergy)
Source: Allergy - November 4, 2009 Category: Allergy & Immunology Authors: G. Pala, P. Pignatti, L. Perfetti, M. Caminati, E. Gentile, G. Moscato Source Type: journals

Global Goods Movement and the Local Burden of Childhood Asthma in Southern California.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Both Long Beach and Riverside have heavy automobile traffic corridors as well as truck traffic and regional pollution originating in the Los Angeles-Long Beach port complex, the largest in the United States. Community-based quantitative risk analyses can improve our understanding of health problems and help promote public health in transportation planning. PMID: 19890167 [PubMed - as supplied by publisher] (Source: American Journal of Public Health)
Source: American Journal of Public Health - November 1, 2009 Category: Global & Universal Authors: Perez L, Künzli N, Avol E, Hricko AM, Lurmann F, Nicholas E, Gilliland F, Peters J, McConnell R Tags: Am J Public Health Source Type: journals

Upper-Airway Cough Syndrome with Latent Eosinophilic BronchitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The objective of this study was to explore the diagnosis and clinical implication of upper-airway cough syndrome with latent eosinophilic bronchitis. Eleven patients with upper-airway cough syndrome and latent eosinophilic bronchitis were retrospectively analyzed for their clinical manifestations, changes of eosinophilia in induced sputum, and cough threshold with capsaicin defined as capsaicin concentration that elicits two or more coughs (C2) and five or more coughs (C5) between pretreatment and post-treatment. All patients reported a history of allergic rhinitis, showed persistent dry cough or small amounts of visc...
Source: Lung - October 28, 2009 Category: Respiratory Medicine Tags: Lung Source Type: journals

Chronic BronchitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Chronic bronchitis is a serious lung disease that may increase the risk of lung cancer. What is the definition of chronic bronchitis? (Source: About.com Lung Cancer)
Source: About.com Lung Cancer - October 27, 2009 Category: Cancer & Oncology Tags: health Source Type: consumer

Probable nitrofurantoin-induced bronchiolitis obliterans with organizing pneumonia.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: An 89-year-old woman developed unresolving BOOP after three years of nitrofurantoin therapy. PMID: 19850785 [PubMed - in process] (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - October 25, 2009 Category: Drugs & Pharmacology Authors: Robinson C, Nyi PP Tags: Am J Health Syst Pharm Source Type: journals

Alcohol Up-Regulates TLR2 Through a NO/cGMP Dependent Pathway.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Alcohol up-regulates TLR2 through a NO/cGMP/PKG dependent pathway in the airway epithelium. This is an important observation in the understanding how alcohol modulates airway inflammation. In addition, this is the first time that cyclic nucleotides have been shown to play a role in the regulation of TLR2. PMID: 19860807 [PubMed - as supplied by publisher] (Source: Alcoholism, Clinical and Experimental Research)
Source: Alcoholism, Clinical and Experimental Research - October 23, 2009 Category: Addiction Authors: Bailey KL, Sisson JH, Romberger DJ, Robinson JE, Wyatt TA Tags: Alcohol Clin Exp Res Source Type: journals

Alcohol Up-Regulates TLR2 Through a NO/cGMP Dependent PathwayEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Alcohol up-regulates TLR2 through a NO/cGMP/PKG dependent pathway in the airway epithelium. This is an important observation in the understanding how alcohol modulates airway inflammation. In addition, this is the first time that cyclic nucleotides have been shown to play a role in the regulation of TLR2. (Source: Alcoholism: Clinical and Experimental Research)
Source: Alcoholism: Clinical and Experimental Research - October 22, 2009 Category: Addiction Authors: Kristina L Bailey, Joseph H. Sisson, Debra J. Romberger, James E. Robinson, Todd A. Wyatt Source Type: journals

Dr. Weil was right: Astragalus herb really helps fight the flu (influenza)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(NaturalNews) The FTC and FDA are terrorizing Dr. Andrew Weil over his true statements about the immune-boosting properties of astragalus. According to the FDA, astragalus has no antiviral or antibacterial properties whatsoever and is of absolutely no use in the human body. Sound bizarre?I thought so too. That's why I asked NaturalNews researchers to assemble a collection of statements in support of Dr. Weil's astragalus statements. This medicinal herb does, indeed, boost healthy immune function and offer protection against influenza. And because it's a multifaceted, complex plant-based medicine, it's not outsmarted by one...
Source: NaturalNews.com - October 22, 2009 Category: Consumer Health Advice Source Type: news

Abelardo Gallego (1879-1930) and his contributions to histotechnology: The Gallego stains.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The Gallego general tissue stain is used in histology and histopathology and stains beautifully connective tissue, in which all nuclei are stained in magenta red, epithelial cytoplasm in red-yellow, connective tissue is stained in brilliant green, muscle in olive green, and keratinized epithelium and blood in grass green. There is also Gallego's method for differential staining of elastic tissue that enables a complete differentiation between elastic and collagenous connective tissue. The elastic tissue is stained in brilliant fuschin red, while collagen is stained in brilliant green. Abelardo Gallego was born in Spain...
Source: Acta Histochemica - October 22, 2009 Category: Biochemistry Authors: Ortiz-Hidalgo C Tags: Acta Histochem Source Type: journals

Dietary patterns and adult asthma: population-based case–control studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Overall there were no clear relations between dietary patterns and adult asthma; associations in nonsupplement users and whites require confirmation. The finding for chronic bronchitis was unexpected and also requires replication. (Source: Allergy)
Source: Allergy - October 19, 2009 Category: Allergy & Immunology Authors: I. Bakolis, R. Hooper, R. L. Thompson, S. O. Shaheen Source Type: journals

Antioxidant and antimicrobial activities of some alpina speciesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Methanol extracts of Alpinia galanga, Alpinia zerumbet, Alpinia zerumbet variegata and Alpinia purpurata were evaluated for total phenolic content (TPC) and antioxidant activities (AOA). The AOA were investigated using 1,1-diphenyl-2-picrylhydrazyl (DPPH), reducing power (RP), ferrous ion chelating as well as[beta]-carotene bleaching assays. High antioxidant activities shown in leaves of A. zerumbet, A. zerumbet variegata and A. purpurata by using DPPH and RP assays were associated with high TPC values. In spite of lower TPC values, A. galanga leaves and flowers showed highest chelating and[beta]-carotene bleaching abiliti...
Source: Journal of Food Biochemistry - October 12, 2009 Category: Food Science Authors: L.F. WONG, Y.Y. LIM, M. OMAR Source Type: journals

Take a deep breath -- more bad news on air pollutionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The consequences of breathing bad air is linked to appendicitis and ear infections, new studies indicate. It's easy to see how air pollution would affect respiratory disease: You breathe in smog-filled miasma all day and the ozone, other noxious gases and small particulate matter therein can make you wheeze and cough. Pollutants can trigger asthma attacks and bronchitis in susceptible individuals. (Source: L.A. Times - Health)
Source: L.A. Times - Health - October 10, 2009 Category: Consumer Health News Source Type: news

Viral pneumonia: epidemiological, clinical, pathophysiological and therapeutic aspectsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The objective of this review article was to show epidemiological, pathophysiological, clinical and therapeutic aspects of viral community-acquired pneumonia. These types of pneumonia are commonly caused by influenza A and B; parainfluenza 1, 2 and 3; respiratory syncytial virus; or adenovirus. We also address the types of pneumonia caused by hantaviruses, metapneumoviruses and rhinoviruses. (Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - October 9, 2009 Category: Respiratory Medicine Source Type: journals

Nitric Oxide Measurement in Chronic CoughEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Chronic cough is a common symptom-based diagnostic challenge for primary care physicians and respiratory specialists. Measurement of exhaled nitric oxide is a convenient, reproducible, and inexpensive point-of-service test. It can simplify the evaluation process of chronic cough by providing information regarding the state of airway inflammation. If exhaled nitric oxide is elevated, this is predictive of a favorable response to inhaled corticosteroids. This has the effect of reducing empirical trials for cough-variant asthma or eosinophilic bronchitis. The inclusion of exhaled nitric oxide in the di...
Source: Lung - October 7, 2009 Category: Respiratory Medicine Tags: Lung Source Type: journals

The Cough Hypersensitivity Syndrome: A Novel Paradigm for Understanding CoughEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract For many years patients with chronic cough have been investigated in an attempt to diagnose the cause of the cough. Here I suggest that the overwhelming majority of patients with chronic cough have a single diagnosis: cough hypersensitivity syndrome. This is demonstrated by the homogeneous nature of the clinical history and investigational results of patients attending cough clinics. The hypersensitivity facet of the syndrome is demonstrated by objective testing with capsaicin and other protussive agents. Within the cough hypersensitivity syndrome there are different phenotypes. Those patients with ...
Source: Lung - October 7, 2009 Category: Respiratory Medicine Tags: Lung Source Type: journals

Development of Predictive Models for Airflow Obstruction in Alpha-1-Antitrypsin DeficiencyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Alpha-1-antitrypsin deficiency is a genetic condition associated with severe, early-onset chronic obstructive pulmonary disease (COPD). However, there is significant variability in lung function impairment among persons with the protease inhibitor ZZ genotype. Early identification of persons at highest risk of developing lung disease could be beneficial in guiding monitoring and treatment decisions. Using a multicenter, family-based study sample (2002–2005) of 372 persons with the protease inhibitor ZZ genotype, the authors developed prediction models for forced expiratory volume in 1 second (FEV1) and the presence o...
Source: American Journal of Epidemiology - October 1, 2009 Category: Epidemiology Authors: Castaldi, P. J., DeMeo, D. L., Kent, D. M., Campbell, E. J., Barker, A. F., Brantly, M. L., Eden, E., McElvaney, N. G., Rennard, S. I., Stocks, J. M., Stoller, J. K., Strange, C., Turino, G., Sandhaus, R. A., Griffith, J. L., Silverman, E. K. Tags: RESEARCH-ARTICLE Source Type: journals

Co-Infection of Leishmania (Viannia) braziliensis and HIV: report of a case of mucosal leishmaniasis in Cochabamba, Bolivia.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe the first case of Leishmania/HIV co-infection reported in Bolivia. Initially hospitalized with a diagnosis of pneumonia and bronchitis, the patient had numerous cutaneous and mucosal lesions caused by Leishmania (Viannia) braziliensis. The patient was also diagnosed as severely immunocompromised because of HIV infection. PMID: 19815865 [PubMed - in process] (Source: The American Journal of Tropical Medicine and Hygiene)
Source: The American Journal of Tropical Medicine and Hygiene - September 30, 2009 Category: Tropical Medicine Authors: Torrico F, Parrado R, Castro R, Marquez CJ, Torrico MC, Solano M, Reithinger R, García AL Tags: Am J Trop Med Hyg Source Type: journals

CAM and Respiratory Disease.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Complementary and alternative medicine is used commonly for respiratory diseases. This review summarizes data that identify potential links between dietary intake and asthma, and results of interventional trials of herbal substances for the treatment of asthma, chronic obstructive pulmonary disease, and acute bronchitis. PMID: 19841248 [PubMed - in process] (Source: Nutrition in Clinical Practice)
Source: Nutrition in Clinical Practice - September 30, 2009 Category: Nutrition Authors: Sorkness RL Tags: Nutr Clin Pract Source Type: journals

Plastic Bronchitis: An Unusual Cause of AtelectasisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Respiration (DOI:10.1159/000243711) (Source: Respiration)
Source: Respiration - September 29, 2009 Category: Respiratory Medicine Source Type: journals

Chronic bronchitis before age 50 years predicts incident airflow limitation and mortality risk [Epidemiology]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Among adults <50 years old, chronic bronchitis unaccompanied by airflow limitation may represent an early marker of susceptibility to the effects of cigarette smoking on systemic inflammation and long-term risk for chronic obstructive pulmonary disease and all-cause mortality. (Source: Thorax)
Source: Thorax - September 28, 2009 Category: Respiratory Medicine Authors: Guerra, S, Sherrill, D L, Venker, C, Ceccato, C M, Halonen, M, Martinez, F D Tags: Epidemiologic studies, TB and other respiratory infections, Child health, Inflammation, Asthma, Bronchitis, Health education, Smoking, Tobacco use, Tobacco use (youth) Epidemiology Source Type: journals

[Epidemiology] Chronic bronchitis before age 50 years predicts incident airflow limitation and mortality riskEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Among adults <50 years old, chronic bronchitis unaccompanied by airflow limitation may represent an early marker of susceptibility to the effects of cigarette smoking on systemic inflammation and long-term risk for chronic obstructive pulmonary disease and all-cause mortality. (Source: Thorax)
Source: Thorax - September 27, 2009 Category: Respiratory Medicine Authors: Guerra, S, Sherrill, D L, Venker, C, Ceccato, C M, Halonen, M, Martinez, F D Tags: Epidemiologic studies, TB and other respiratory infections, Child health, Inflammation, Asthma, Bronchitis, Health education, Smoking, Tobacco use, Tobacco use (youth) Epidemiology Source Type: journals

Protection of chickens against infectious bronchitis by a recombinant fowlpox virus co-expressing IBV-S1 and chicken IFNgamma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study demonstrated that chicken type II interferon increased the immunoprotective efficacy of rFPV-IBVS1-ChIFNgamma and normal weight gain in vaccinated chickens although it inhibited serum antibody production. PMID: 19786144 [PubMed - as supplied by publisher] (Source: Vaccine)
Source: Vaccine - September 24, 2009 Category: Allergy & Immunology Authors: Wang YF, Sun YK, Tian ZC, Shi XM, Tong GZ, Liu SW, Zhi HD, Kong XG, Wang M Tags: Vaccine Source Type: journals

[Benign intracranial hypertension: Experience over 18 years.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present our experience in benign intracranial hypertension (BIH) cases, excluding traumatic brain injuries, encephalitis and meningitis. RESULTS: Among the entire neuropaediatric database, with 10,720 children in 18 years, 31 cases had the diagnosis of BIH. Sixteen aged between 2.3 and 8.9 months (75% males), all of them with transient bulging fontanelle, and 15 aged between 4.4 and 13.7 years (73.3% females), all of them with papilloedema which was subsequently resolved. A total of 75% of infants had recently finished corticosteroid treatment for bronchitis. In the older children, there was 1 case associated with exces...
Source: Anales de Pediatria - September 22, 2009 Category: Pediatrics Authors: Monge Galindo L, Pérez Delgado R, López-Pisón J, Olloqui-Escalona A, García Íñiguez JP, Ruiz Del Olmo Izuzquiza I, Peña-Segura JL Tags: An Pediatr (Barc) Source Type: journals

Development of a TaqMan RT-PCR assay for the detection of infectious bronchitis virus in chickens, and comparison of RT-PCR and virus isolation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study the development of a real-time TaqMan(R) RT-PCR targeting the highly conserved nucleocapsid (N) gene of IBV and including an internal PCR control is described. The assay was specific for IBV and did not detect other avian pathogens, including turkey coronaviruses. A comparative limit of detection was determined for M41, an embryo-adapted strain, and IS/885/00, a poorly embryo-adapted variant. For M41 real-time RT-PCR and virus isolation were one or two times more sensitive than RT-PCR targeting the N or spike glycoprotein (S1) genes, respectively. For IS/885/00, real-time RT-PCR was more sensitive by ten-fold...
Source: Journal of Virological Methods - September 21, 2009 Category: Virology Authors: Meir R, Maharat O, Farnushi Y, Simanov L Tags: J Virol Methods Source Type: journals

Gene 'Switch' May Help Drive Excess Fluid in LungsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Finding could lead to treatments for bronchitis, asthma, researchers say (Source: Forbes.com Health News)
Source: Forbes.com Health News - September 15, 2009 Category: Consumer Health News Source Type: news

Using Measurement Of Chemical In Blood May Help Reduce Overuse Of Antibiotics For Lower Respiratory Tract InfectionsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The use of guidelines for treatment of lower respiratory tract infections such as bronchitis and pneumonia determined by measurements of a chemical in the blood known as procalcitonin resulted in lower rates of antibiotic use and associated adverse effects, and similar rates of adverse outcomes compared to standard guidelines, according to a study in the September 9 issue of JAMA. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 15, 2009 Category: Consumer Health News Tags: Respiratory / Asthma Source Type: news

Oral microbial and respiratory status of persons with mental retardation/intellectual and developmental disability: an observational cohort studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Potentially pathogenic microorganisms in the oral cavity and poor oral status significantly increased the risk of developing respiratory infections, including pneumonia, in persons with IDD. The results suggest that colonization with these microorganisms may persist despite routine tooth brushing. Meticulous comprehensive oral hygiene of the oral cavity may be needed to reduce oropharyngeal microbial load. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - September 13, 2009 Category: ENT & OMF Authors: Catherine J. Binkley, Gilbert S. Haugh, Dinah H. Kitchens, Debra L. Wallace, Daniel I. Sessler Tags: Oral Medicine Source Type: journals

Gene variants linked to chronic bronchitis in COPDEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Several polymorphisms in the gene encoding cytotoxic T-lymphocyte antigen 4 appear to be associated with the presence of chronic bronchitis in chronic obstructive pulmonary disease, study results show. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - September 11, 2009 Category: Respiratory Medicine Source Type: news

Intensive hog farming operations and self-reported health among nearby rural residents in Ottawa, CanadaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: While our findings suggest that living in close proximity to an IHF may adversely affect HRQOL these should be interpreted cautiously due to a lack of direct measures of environmental exposures, and possible biases inherent in the use of self-reported health measures. (Source: BMC Public Health - Latest articles)
Source: BMC Public Health - Latest articles - September 9, 2009 Category: Consumer Health News Authors: Paul VilleneuveAmira AliLaurel ChallacombeSophie Hebert Source Type: journals

ORIGINAL CONTRIBUTION: Effect of Procalcitonin-Based Guidelines vs Standard Guidelines on Antibiotic Use in Lower Respiratory Tract Infections: The ProHOSP Randomized Controlled TrialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion In patients with LRTIs, a strategy of PCT guidance compared with standard guidelines resulted in similar rates of adverse outcomes, as well as lower rates of antibiotic exposure and antibiotic-associated adverse effects. Trial Registration isrctn.org Identifier: ISRCTN95122877 (Source: JAMA)
Source: JAMA - September 7, 2009 Category: Journals (General) Authors: Schuetz, P., Christ-Crain, M., Thomann, R., Falconnier, C., Wolbers, M., Widmer, I., Neidert, S., Fricker, T., Blum, C., Schild, U., Regez, K., Schoenenberger, R., Henzen, C., Bregenzer, T., Hoess, C., Krause, M., Bucher, H. C., Zimmerli, W., Mueller, B., Tags: Pulmonary Diseases, Pulmonary Diseases, Other, Quality of Care, Quality of Care, Other, Randomized Controlled Trial, Drug Therapy, Drug Therapy, Other Original Contribution Source Type: journals

Flu vaccination rates low in Spanish bronchitis patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
More than a third of Spanish patients with chronic bronchitis are not being vaccinated against influenza, say researchers who call for measures to improve vaccination rates among this vulnerable group. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - September 5, 2009 Category: Respiratory Medicine Source Type: news

Usefulness of induced sputum in the diagnostics of selected chronic inflammatory airway diseases.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: 1. Cytological examination of induced sputum is a good test supporting the diagnostic evaluation of chronic inflammatory diseases of the respiratory tract. 2. The percentage of eosinophils in induced sputum exceeding 2.8% is a very good indicator of asthma. PMID: 19722139 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - September 3, 2009 Category: Respiratory Medicine Authors: Sozańska E, Barczyk A, Biedroń-Machura M, Pierzchała W Tags: Pneumonol Alergol Pol Source Type: journals

Fulminant pertussis: A multi-center study with new insights into the clinico-pathological mechanismsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Pertussis carries a high risk of mortality in very young infants. The mechanism of refractory cardio-respiratory failure is complex and not clearly delineated. We aimed to examine the clinico-pathological features and suggest how they may be related to outcome, by multi-center review of clinical records and post-mortem findings of 10 patients with fulminant pertussis (FP). All cases were less than 8 weeks of age, and required ventilation for worsening respiratory symptoms and inotropic support for severe hemodynamic compromise. All died or underwent extra corporeal membrane oxygenation (ECMO) within 1 week. All had increas...
Source: Pediatric Pulmonology - September 1, 2009 Category: Respiratory Medicine Authors: Mohammad Sawal, Marta Cohen, Jose E. Irazuzta, Ramani Kumar, Christine Kirton, Marie-Anne Brundler, Clair Anne Evans, John Andrew Wilson, Parakkal Raffeeq, Amer Azaz, Alexandre T. Rotta, Ajay Vora, Amit Vohra, Patricia Abboud, L. David Mirkin, Mehrengise Source Type: journals

Development of Predictive Models for Airflow Obstruction in Alpha-1-Antitrypsin Deficiency.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Alpha-1-antitrypsin deficiency is a genetic condition associated with severe, early-onset chronic obstructive pulmonary disease (COPD). However, there is significant variability in lung function impairment among persons with the protease inhibitor ZZ genotype. Early identification of persons at highest risk of developing lung disease could be beneficial in guiding monitoring and treatment decisions. Using a multicenter, family-based study sample (2002-2005) of 372 persons with the protease inhibitor ZZ genotype, the authors developed prediction models for forced expiratory volume in 1 second (FEV(1)) and the presence o...
Source: Am J Epidemiol - September 1, 2009 Category: Epidemiology Authors: Castaldi PJ, Demeo DL, Kent DM, Campbell EJ, Barker AF, Brantly ML, Eden E, McElvaney NG, Rennard SI, Stocks JM, Stoller JK, Strange C, Turino G, Sandhaus RA, Griffith JL, Silverman EK Tags: Am J Epidemiol Source Type: journals

Common community acquired infections and subsequent risk of chronic lymphocytic leukaemiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Emerging evidence supports a role for immune-related factors in the causation of chronic lymphocytic leukaemia (CLL). Using the population-based U.S. Surveillance Epidemiology and End Results-Medicare database, 10 171 elderly CLL patients and 122 531 frequency-matched controls were identified in order to evaluate several community acquired infections associated with subsequent CLL risk. Odds ratios (ORs) were adjusted for gender, age, race, calendar year and number of physician claims. CLL risk was increased following Medicare claims for sinusitis (OR = 1·11; 95% CI = 1·05[ndash]1·17), pharyngitis (OR = 1·15; 1·08[nda...
Source: British Journal of Haematology - August 31, 2009 Category: Hematology Authors: Lesley A. Anderson, Ola Landgren, Eric A. Engels Source Type: journals

Association of the cysteinyl leukotriene receptor 1 gene with atopy in the British 1958 birth cohortEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: These data suggest that a CYSLTR1 polymorphism previously shown to affect the gene transcription in vitro might influence the risk of atopy in the female white population with suggestive evidence of heterozygote vigor. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - August 31, 2009 Category: Allergy & Immunology Authors: Nathalie P. Duroudier, David P. Strachan, John D. Blakey, Ian P. Hall Tags: Mechanisms of allergy and clinical immunology Source Type: journals