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Genomic Tandem Repeat Analysis Proves Laboratory-Acquired Brucellosis in Veterinary (Camel) Diagnostic Laboratory in the United Arab EmiratesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a case of a 64-year-old veterinarian working in a state camel veterinary laboratory who was diagnosed with and treated for acute brucellosis with complicating epididymo-orchitis. Genomic tandem repeat analysis (MLVA-16) revealed identical Brucella strains in patient cultures and from different dromedary milk samples positive for Brucella melitensis, thereby confirming the diagnosis of a laboratory acquired infection. The case illustrates the high (airborne) infectivity of brucellosis in laboratory settings and the need to implement vigorous bio-safety measures in veterinary laboratories handling camel specimen di...
Source: Zoonoses and Public Health - November 19, 2009 Category: Infectious Diseases Authors: J. S. zur Wiesch, D. Wichmann, I. Sobottka, H. Rohde, G. Schmoock, R. Wernery, S. Schmiedel, G. Dieter Burchard, F. Melzer Source Type: journals

Persistence of an atherogenic lipid profile after treatment of acute infection with brucella [Patient-Oriented and Epidemiological Research]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Serum lipid changes during infection may be associated with atherogenesis. No data are available on the effect of Brucellosis on lipids. Lipid parameters were determined in 28 patients with Brucellosis on admission and 4 months following treatment and were compared with 24 matched controls. Fasting levels of total cholesterol (TC), HDL-cholesterol (HDL-C), triglycerides, apolipoproteins (Apo) A, B, E CII, and CIII, and oxidized LDL (oxLDL) were measured. Activities of serum cholesterol ester transfer protein (CETP), paraoxonase 1 (PON1), and lipoprotein-associated phospholipase A2 (Lp-PLA2) and levels of cytokines [interle...
Source: The Journal of Lipid Research - November 13, 2009 Category: Lipidology Authors: Apostolou, F., Gazi, I. F., Kostoula, A., Tellis, C. C., Tselepis, A. D., Elisaf, M., Liberopoulos, E. N. Tags: Patient-Oriented and Epidemiological Research Source Type: journals

Advanced canine reproductive techniques: the most current approaches in breeding managementEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Dogs are arguably one of the most difficult species in which to manage reproduction. Their estrous cycle and reproductive physiology differ from most other domestic species. In discussing the most current assisted reproductive techniques, it is important to review the canine estrous cycle, as well as the current available methods to manipulate the estrous cycle. Accurate knowledge of breeding timing techniques including vaginal cytology, vaginoscopy, and progesterone and lutenizing hormone testing are vital to proper breeding management, as improper timing is the most frequent cause for suspected infertility. In addition, ...
Source: Journal of Veterinary Behavior: Clinical Applications and Research - November 1, 2009 Category: Veterinary Research Authors: C. O'Connor, A.M. Traas Tags: Abstracts Source Type: journals

Effect of resveratrol on helicobacter pylori-induced interleukin-8 secretion, reactive oxygen species generation and morphological changes in human gastric epithelial cells.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Inflammatory cytokine interleukin-8 (IL-8) and reactive oxygen species (ROS) overexpressed in the gastric mucosa when exposed to Helicobacter pylori, defined as a class I carcinogen. Moreover, infection with H. pylori leads to morphological changes in co-cultured cells known as hummingbird phenomenon along with increased motility. Resveratrol, a highly abundant polyphenol in red grapes, has shown anti-inflammatory, anti-cancer, cardioprotective and neuroprotective activities. However, the effect of resveratrol in H. pylori-infected cells has not been investigated. The present study was, therefore, aimed to evaluate the...
Source: Biological and Pharmaceutical Bulletin - November 1, 2009 Category: Drugs & Pharmacology Authors: Zaidi SF, Ahmed K, Yamamoto T, Kondo T, Usmanghani K, Kadowaki M, Sugiyama T Tags: Biol Pharm Bull Source Type: journals

Application and evaluation of the MLVA typing assay for the Brucella abortus strains isolated in KoreaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The MLVA assay has enough discrimination power in the Brucella species level and can be utilized as a tool for the epidemiological trace-back of the B. abortus isolates. But it is important to consider that Brucella isolates may be capable of undergoing minor changes at some loci in the course of infection or in accordance with the changes of the host. (Source: BMC Microbiology - Latest articles)
Source: BMC Microbiology - Latest articles - October 29, 2009 Category: Microbiology Authors: Moon HerSung-Il KangDong-Hee ChoYun-Sang ChoIn-Yeong HwangYoung-Ran HeoSuk-Chan JungHan-Sang Yoo Source Type: journals

An unusual case of neurobrucellosis presenting with unilateral abducens nerve palsy: clinical and MRI findings.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this report, we present unusual clinical and magnetic resonance imaging (MRI) findings in a patient with neurobrucellosis and unilateral abducens nerve palsy. Her MRI showed punctate leptomeningeal enhancement of the cerebellum on contrast-enhanced T1-weighted images, and a focal area of hyperintensity in the splenium of the corpus callosum on T2-weighted images. PMID: 19862675 [PubMed - as supplied by publisher] (Source: Diagnostic and Interventional Radiology : The Turkish Society of Radiology)
Source: Diagnostic and Interventional Radiology : The Turkish Society of Radiology - October 27, 2009 Category: Radiology Authors: Ozkavukcu E, Tuncay Z, Selcuk F, Erden I Tags: Diagn Interv Radiol Source Type: journals

Comparison of basal broth media for the optimal laboratory recovery ofCampylobacter jejuni andCampylobacter coliEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion These studies support laboratory employment of either BHIYE or TSBYE for optimal recovery ofC. jejuni andC. coli and avoidance of nutrient broth. Content Type Journal ArticleCategory Original PaperDOI 10.1007/BF03167693Authors J. E. Moore, Belfast City Hospital Northern Ireland Public Health Laboratory, Department of Bacteriology BT9 7AD Belfast Northern Ireland Journal Irish Journal of Medical ScienceOnline ISSN 1863-4362Print ISSN 0021-1265 Journal Volume Volume 169 Journal Issue Volume 169, Number 3 / July, 2000 (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 23, 2009 Category: Journals (General) Tags: Irish Journal of Medical Science Source Type: journals

Brucella endocarditis: a report from Iran.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Endocarditis is a rare focal complication of brucellosis but the most common cause of mortality. The diagnosis of the complications of endemic diseases is therefore important. We evaluated Brucella endocarditis cases in a teaching hospital in Iran between April 1998 and March 2006. Nine patients with a median age of 38.11 years were recorded, of whom seven (77.7%) were male. Underlying cardiopathy was present in three patients (33.3%). The median duration of the symptoms prior to diagnosis was 5.33 months. Endocarditis involved the aortic valve in six cases (66.6%), the mitral valve in two cases (22.2%) and the aortic ...
Source: Tropical Doctor - October 22, 2009 Category: Tropical Medicine Authors: Esmailpour N, Borna S, Nejad MR, Badie SM, Badie BM, Hadadi A Tags: Trop Doct Source Type: journals

Survival of the fittest: how Brucella strains adapt to their intracellular niche in the hostEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Brucella strains produce abortion and infertility in their natural hosts and a zoonotic disease in humans known as undulant fever. These bacteria do not produce classical virulence factors, and their capacity to successfully survive and replicate within a variety of host cells underlies their pathogenicity. Extensive replication of the brucellae in placental trophoblasts is associated with reproductive tract pathology in natural hosts, and prolonged persistence in macrophages leads to the chronic infections that are a hallmark of brucellosis in both natural hosts and humans. This review describes ...
Source: Medical Microbiology and Immunology - October 14, 2009 Category: Microbiology Tags: Medical Microbiology and Immunology Source Type: journals

Maternal and Congenital Brucellosis in Texas: Changing Travel Patterns and Laboratory ImplicationsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Brucellosis is an uncommon disease in the US, but Texas reports approximately a third of cases. We review the investigation of a pair of mother-infant cases that were unique in the demographics, the nature of travel exposure and the resulting brucellosis exposure in a hospital’s delivery suite and laboratory. These cases illustrate the changing nature of travel and the need to obtain a relevant travel history and adequate laboratory procedures. Clinicians and laboratory workers in Texas need to understand that brucellosis remains an endemic disease, but that its epidemiology is changing. Conten...
Source: Journal of Immigrant and Minority Health - October 3, 2009 Category: Global & Universal Tags: Journal of Immigrant and Minority Health Source Type: journals

Immobilization strategies of Brucella particles on optical fibers for use in chemiluminescence immunosensors.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Immunosensors are powerful analytical tools in clinical and veterinary diagnostics. This has led us to design a chemiluminescent immunosensor aimed at identifying anti-Brucella antibodies using optical fibers as the transducer. In order to develop the optimal transducer, to achieve an optimal chemical modification thereby allowing an optimal covalent binding of the protein receptor, several cleaning strategies and silane coupling agents were investigated. Brucella killed organisms were used as a model receptor for quantifying anti-Brucella IgG antibodies in a suspension compared to conventional colorimetric and chemilu...
Source: Talanta - September 30, 2009 Category: Chemistry Authors: Liebes Y, Amir L, Marks RS, Banai M Tags: Talanta Source Type: journals

Ocular involvement in brucellosis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Because ocular involvement of brucellosis is frequent in endemic regions, detailed ophthalmic examination of all patients with brucellosis should be done routinely. Ocular brucellosis should be considered in the differential diagnosis of all forms of uveitis or choroiditis in endemic regions, and these patients should undergo serologic screening for brucellosis. PMID: 19789599 [PubMed - in process] (Source: Canadian Journal of Ophthalmology)
Source: Canadian Journal of Ophthalmology - September 30, 2009 Category: Opthalmology Authors: Sungur GK, Hazirolan D, Gurbuz Y, Unlu N, Duran S, Duman S Tags: Can J Ophthalmol Source Type: journals

Perforation of the mitral valve due to Brucella endocarditis as a late complication diagnosed perioperatively.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19819801 [PubMed - as supplied by publisher] (Source: Anadolu Kardiyol Der...)
Source: Anadolu Kardiyol Der... - September 30, 2009 Category: Cardiology Authors: Gürbüz A, Yetkin U, Lafçı B, Postacı N, Ozcem B, Yürekli I Tags: Anadolu Kardiyol Derg Source Type: journals

Seroprevalence of Q-fever, brucellosis and leptospirosis in farmers and agricultural workers in Bari, southern ItalyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Clinical Microbiology and Infection)
Source: Clinical Microbiology and Infection - September 27, 2009 Category: Microbiology Authors: R. Monno, L. Fumarola, P. Trerotoli, D. Cavone, T. Massaro, L. Spinelli, C. Rizzo, M. Musti Source Type: journals

Travel-Related Cerebro-Meningeal Infections: The 8-Year Experience of a French Infectious Diseases UnitEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. Among the diversified etiological spectrum of CMI, cosmopolitan infections are widely predominant, particularly viral infections, followed by tropical causes, of which malaria is the leading disease in returnees from endemic areas. The diagnostic approach should be driven by history and physical examination. Key investigations include: blood smear, cerebrospinal fluid polymerase chain reaction and culture as well as neuroimaging. Management should focus on curable causes. (Source: Journal of Travel Medicine)
Source: Journal of Travel Medicine - September 23, 2009 Category: Infectious Diseases Authors: Christophe Rapp, Olivier Aoun, Cécile Ficko, Patrick Imbert, Régine Barruet, Thierry Debord Source Type: journals

A comparative trial of three therapeutic regimens: ciprofloxacin-rifampin, ciprofloxacin-doxycycline and doxycycline-rifampin in the treatment of brucellosis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study was designed to compare the efficacy of ciprofloxacin plus rifampin (CR) and ciprofloxacin plus doxycycline (CD) versus doxycycline plus rifampin (DR) in the treatment of brucellosis. A total of 178 patients with brucellosis who were referred to the Sina Hospital, Hamedan, Iran, were included. The responses to therapy were observed in 166 cases (93.7%) - 59 were in the DR group, 59 in the CR group and 48 in the CD group. No significant differences in the therapeutic responses were observed (P = 0.09). Relapse was observed in 11.7% (DR 7.7%, CR 8.3% and CD 17.5%) after a six-month follow-up. No significant differ...
Source: Tropical Doctor - September 20, 2009 Category: Tropical Medicine Authors: Keramat F, Ranjbar M, Mamani M, Hashemi SH, Zeraati F Tags: Trop Doct Source Type: journals

Neurobrucellosis: an evaluation of a rare presentation of brucellosis from a tertiary care centre in Central Anatolia, Turkey.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe our experience of the diagnosis, treatment and final outcome of patients with neurobrucellosis at the Erciyes University Gevher Nesibe Hospital, a tertiary referral centre in Central Anatolia, Turkey. Thirty-six adult patients were diagnosed with neurobrucellosis from January 1997 to December 2006. Headache and fever were the most common symptoms. Neck stiffness was present in 25 patients. Brucella spp was isolated from the blood of nine patients and from the cerebrospinal fluid of 11. Doxycycline (by mouth) plus rifampin (by mouth) with ceftriaxone (intravenously) were the most common treatment choices. Three ...
Source: Tropical Doctor - September 20, 2009 Category: Tropical Medicine Authors: Demiraslan H, Metan G, Mese EA, Yildiz O, Aygen B, Sumerkan B, Doganay M Tags: Trop Doct Source Type: journals

A case of Brucella endocarditis in association with superficial femoral artery thrombus.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report here a case of Brucella endocarditis associated with superficial femoral artery thrombus. The patient was treated only with medical treatment. The clinical significance of the case was the presence of two rare complications of brucellosis:endocarditis and arterial thrombus. PMID: 19762588 [PubMed - in process] (Source: Tropical Doctor)
Source: Tropical Doctor - September 20, 2009 Category: Tropical Medicine Authors: Caylan R, Keske S, Durmaz T, Keles T, Tasyaran MA Tags: Trop Doct Source Type: journals

Outer membrane vesicles of helicobacter pylori TK1402 are involved in biofilm formationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: The results suggested that OMV produced from TK1402 play an important role in biofilm formation in strain TK1402. (Source: BMC Microbiology - Latest articles)
Source: BMC Microbiology - Latest articles - September 14, 2009 Category: Microbiology Authors: Hideo YonezawaTakako OsakiSatoshi KurataMinoru FukudaHayato KawakamiKuniyasu OchiaiTomoko HanawaShigeru Kamiya Source Type: journals

Performance characteristics of the Euroimmun enzyme-linked immunosorbent assay kits for Brucella IgG and IgMEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Brucella IgG and IgM ELISA kits manufactured by Euroimmun (Lubeck, Germany) were evaluated in a reference laboratory setting. Intraassay coefficient of variation (CV) values were ≤10% for positive sera and ≤12% for negative sera; interassay CVs were ≤12% for positive sera and ≤20% for negative sera. The tube agglutination test (TAT) was performed on 51 sera exhibiting various ELISA reactivity profiles. All 18 sera negative for both IgG and IgM by ELISA were TAT negative (titer (Source: Diagnostic Microbiology and Infectious Disease)
Source: Diagnostic Microbiology and Infectious Disease - September 14, 2009 Category: Microbiology Authors: Harry E. Prince, Janice Lopez, Cindy Yeh, Joselita Tablante, Joseph Morgan, Beverly Kaneko, Paul Duffey Tags: Bacteriology Source Type: journals

The polymeric antigen BLSOmp31 confers protection against Brucella ovis infection in rams.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We have engineered the polymeric vaccine BLSOmp31 by decorating the highly immunogenic and decameric Brucella lumazine synthase with an exposed loop of the Brucella outer membrane protein Omp31. In the present study, we have immunized different groups of rams with the recombinant chimera rBLSOmp31 in two different adjuvants (Incomplete Freund Adjuvant-IFA and QUIL A) and with the plasmid pCIBLSOmp31 administered either by i.m. injection alone or by using electroporation. In addition, we have used a heterologous prime-boost strategy consisting of repeated pCIBLSOmp31 electroporation priming followed by a single protein ...
Source: Vaccine - September 9, 2009 Category: Allergy & Immunology Authors: Estein SM, Fiorentino MA, Paolicchi FA, Clausse M, Manazza J, Cassataro J, Giambartolomei GH, Coria LM, Zylberman V, Fossati CA, Kjeken R, Goldbaum FA Tags: Vaccine Source Type: journals

Participation of ezrin in bacterial uptake by trophoblast giant cellsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Ezrin associates with Hsc70 that locates on the membrane of TG cells and participates in the bacterial uptake by TG cells. (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - September 8, 2009 Category: Endocrinology Authors: Kenta WatanabeMasato TachibanaSuk KimMasahisa Watarai Source Type: journals

Brucella canis Causing Infection in an HIV-Infected PatientEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Vector-Borne and Zoonotic Diseases , Vol. 0, No. 0. (Source: Vector-Borne and Zoonotic Diseases)
Source: Vector-Borne and Zoonotic Diseases - September 2, 2009 Category: Infectious Diseases Tags: article Source Type: journals

Pyrexia of unknown origin: a case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. Our patient was indeed suffering from neurobrucellosis. Brucellosis is a frequently missed cause of pyrexia of unknown. More importantly, our case highlights that in this era taking help from our professional colleagues over the globe is easy which can improve patient care greatly. (Source: Cases Journal)
Source: Cases Journal - August 31, 2009 Category: Journals (General) Source Type: journals

Brucellosis in a Singaporean with prolonged fever.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report brucellosis in a 52-year-old man, who had a recent travel history to Saudi Arabia, and who presented with prolonged fever and deranged liver enzymes. In view of the rarity of brucellosis and its potential life-threatening complications, patients returning from an endemic country need to be questioned for possible Brucella exposure, to ensure that diagnostic tests and treatment are carried out in a timely fashion. In addition to notifying the authorities, the clinician should also warn the laboratory early as cultures of brucellosis are highly transmissible and are one of the most common laboratory-acquired infect...
Source: Singapore Medical Journal - August 31, 2009 Category: Journals (General) Authors: Seow CJ, Barkham T, Wong PM, Lin L, Pada SK, Tan SH Tags: Singapore Med J Source Type: journals

Multiple Cranial Nerve Involvement Caused by Brucella melitensisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 23-year-old woman was referred to physicians for headache starting 20 days previously, nausea and vomiting two weeks prior to presentation. Southern Medical Journal (Source: Medscape Ophthalmology Headlines)
Source: Medscape Ophthalmology Headlines - August 25, 2009 Category: Opthalmology Tags: Internal Medicine Source Type: info

Brucella liver abscess; imaging approach, differential diagnosis, and therapeutic management: a case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a new case of a brucellar liver abscess (brucelloma) in a young woman without previous remote brucellosis who presented with pronounced systemic and mild local symptoms. Brucelloma is the result of calcification of a granoulomatous reaction induced by persistent Brucella in macrophages. It represents a rare manifestation that follows previously undetected brucellosis. We describe the findings in plain radiograph, ultrasound, computed tomography, and magnetic resonance images. Together with the positive serology, imaging yielded important elements supporting the diagnosis. Modern radiological techniques also contr...
Source: Cases Journal - August 24, 2009 Category: Journals (General) Source Type: journals

Efficacy of moxifloxacin or gatifloxacin as prophylaxis against experimental murine Brucella melitensis infectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: The prophylactic potential of moxifloxacin and gatifloxacin was assessed in comparison with doxycycline, an established therapeutic antibiotic, to limit or control infection by Brucella melitensis in an experimental mouse model, determined by reduced bacterial burden in the spleen. Although moxifloxacin was found to have a small protective effect when administered 6h following infection, neither moxifloxacin nor gatifloxacin showed significant efficacy in vivo. In comparison, doxycycline provided significant protection when prophylaxis was started at 6h, 7 days or 14 days following infection. Overall, these resul...
Source: International Journal of Antimicrobial Agents - August 16, 2009 Category: Drugs & Pharmacology Authors: Helen S. Atkins, Stephen Spencer, Simon D. Brew, Thomas R. Laws, Rachel E. Thirlwall, Alastair P. MacMillan, Timothy J.G. Brooks, Andrew J.H. Simpson Tags: Short communications Source Type: journals

Paenochrobactrum gallinarii gen. nov., sp. nov., isolated from the air of a duck barn and reclassification and emendation of Pseudochrobactrum glaciei as Paenochrobactrum glaciei comb. nov.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A gram-negative, rod-shaped, oxidase positive, non-spore-forming, non motile bacterium (Sa25T) was isolated from the air of a duck barn. 16S rRNA gene and recA sequence analyses clearly allocated the isolate in the vicinity of the Brucella-Ochrobactrum-Pseudochrobactrum group with the next relative Pseudochrobactrum glaciei KMM 3858T. This allocation was confirmed by the quinone system (ubiquinone Q-10), fatty acid data (major fatty acids: C18:1omega7c and C19:0 cycloomega8c) and polar lipid profile (major components: diphosphatidylglycerol, phosphatidylmonomethylethanolamine, phosphatidylethanolamine, phosphatidylglyc...
Source: International Journal of Systematic and Evolutionary Microbiology - August 13, 2009 Category: Microbiology Authors: Kämpfer P, Martin E, Lodders N, Jäckel U, Huber BE, Schumann P, Langer S, Busse HJ, Scholz H Tags: Int J Syst Evol Microbiol Source Type: journals

The evaluation of a user-friendly lateral flow assay for the serodiagnosis of human brucellosis in KazakhstanEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Serum samples from all patients with culture-confirmed brucellosis including those with chronic disease from Kazakhstan tested positive in the serum agglutination test for titers ≥1:25 and reacted in the Brucella immunoglobulin M/immunoglobulin G lateral flow assay (LFA) confirming the high sensitivity of these assays. The strong reactivity in the LFA observed for the majority (92.1%) of the samples from the patients with culture-confirmed brucellosis together with the user-friendliness of the assay procedure makes the LFA ideal for the confirmation of brucellosis in endemic areas in Kazakhstan. The Rose Bengal...
Source: Diagnostic Microbiology and Infectious Disease - August 13, 2009 Category: Microbiology Authors: Sulushash Mizanbayeva, Henk L. Smits, Katya Zhalilova, Theresia H. Abdoel, Stanislaw Kozakov, Kenes S. Ospanov, Philip H. Elzer, James T. Douglas Tags: Bacteriology Source Type: journals

Eight enrichment broths for the isolation of Campylobacter jejuni from inoculated suspensions and ground porkEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Cell recovery from the eight enrichment broths was dependent on the sample type and the state of the cells. The use of the appropriate broth is important for the rapid and efficacious enrichment of Camp. jejuni. In particular, heat-injured Camp. jejuni require a longer cultivation time and a suitable enrichment broth.Significance and Impact of the Study: The results from the present study provide information for selecting the most appropriate enrichment broth for Camp. jejuni and may contribute to improved detection methods for the organism. (Source: Letters in Applied Microbiology)
Source: Letters in Applied Microbiology - August 12, 2009 Category: Microbiology Authors: S.A. Kim, Y.M. Lee, I.G. Hwang, D.H. Kang, G.J. Woo, M.S. Rhee Source Type: journals

Iowa Supreme Court Rules Brucellosis Qualifies As Injury For Workers' CompensationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
DES MOINES, Iowa - In an opinion of first impression, the Iowa Supreme Court said July 10 that contracting brucellosis while working in a hog packing factory is an occupational injury (IBP Inc. v. Lee Burress, No. 07-1887, Iowa Sup.; 2009 Iowa Sup. LEXIS 63). Full story on lexis.com (Source: LexisNexis® Mealey's™ Emerging Toxic Torts Legal News)
Source: LexisNexis® Mealey's™ Emerging Toxic Torts Legal News - August 6, 2009 Category: Medical Law Source Type: info

Brucella inopinata sp. nov., isolated from a breast implant infection.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A Gram-negative, non-motile, non-spore-forming coccoid bacterium (strain BO1T) has recently been isolated from a breast implant wound of a 71-year-old female patient with clinical signs of brucellosis. Affiliation of strain BO1T to the genus Brucella was confirmed by polyamine pattern, polar lipid profile, fatty acid profile, quinone system, DNA-DNA hybridization studies, and by insertion sequence 711 (IS711)-specific PCR. Strain BO1T harboured four to five copies of the Brucella specific insertion element IS711, displaying a unique banding pattern and exhibited a unique 16S rRNA gene sequence and also grouped separate...
Source: International Journal of Systematic and Evolutionary Microbiology - August 5, 2009 Category: Microbiology Authors: Scholz HC, Nöckler K, Göllner C, Bahn P, Vergnaud G, Tomaso H, Al-Dahouk S, Kämpfer P, Cloeckaert A, Marquart M, Zygmunt MS, Whatmore AM, Pfeffer M, Huber B, Busse HJ, De BK Tags: Int J Syst Evol Microbiol Source Type: journals

Brucella microti: the genome sequence of an emerging pathogen.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Contrary to expectations from the phenotypic analysis, the genome sequence of B. microti is highly similar to that of known Brucella species, and is remotely related to the one of O. anthropi. How the few differences in gene content between B. microti and B. suis 1330 could result in vastly different phenotypes remains to be elucidated. This unexpected finding will complicate the task of identifying virulence determinants in the Brucella genus. The genome sequence of B. microti will serve as a model for differential expression analysis and complementation studies. Our results also raise some concerns about the...
Source: BMC Genomics - Latest articles - August 3, 2009 Category: Genetics & Stem Cells Authors: Stephane AudicMagali LescotJean-Michel ClaverieHolger Scholz Source Type: journals

Staphylococcus microti sp. nov., isolated from the common vole (Microtus arvalis).Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Two strains of Gram-positive cocci were isolated from viscera of common voles, Microtus arvalis (Pallas), with generalized Brucella microti infection in the Czech Republic. Biochemical features and phylogenetic analysis based on 16S rRNA gene sequences proved that the strains are representatives of the genus Staphylococcus and assigned Staphylococcus muscae as next relative. A detailed characterization done by ribotyping, rpoB and hsp60 gene sequencing, whole-cell protein analysis and rep-PCR using the (GTG)(5) primer differentiated the two strains from all validly described staphylococci. DNA-DNA hybridization with th...
Source: International Journal of Systematic and Evolutionary Microbiology - August 3, 2009 Category: Microbiology Authors: Novakova D, Pantucek R, Hubalek Z, Falsen E, Busse HJ, Schumann P, Sedlacek I Tags: Int J Syst Evol Microbiol Source Type: journals

Brucella regulators: self-control in a hostile environment.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Brucella is an important zoonotic pathogen for which no human vaccine exists. In an infected host, Brucella resides in macrophages but must coordinate expression of multiple virulence factors for successful cell entry and trafficking to acquire this replicative niche. Brucella responds to environmental signals to regulate virulence strategies that circumvent or blunt the host immune response. The Brucella quorum sensing system is a nexus of control for several Brucella virulence factors including flagellar genes and the type IV secretion system. Other sensory transduction systems, such as BvrRS and the newly described ...
Source: Trends in Microbiology - August 3, 2009 Category: Microbiology Authors: Rambow-Larsen AA, Petersen EM, Gourley CR, Splitter GA Tags: Trends Microbiol Source Type: journals

Prevalence of brucellosis and infectious bovine rhinotracheitis in organized dairy farms in IndiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study was carried out to investigate the prevalence of bovine brucellosis and infectious bovine rhinotracheitis (IBR) in organized dairy farms with history of abortion in India. ELISA and Rose Bengal Plate Test (RBPT) were used to detect the seropositive animals and the test results indicated that 22.18% and 13.78% animals were declared as sero-positive by ELISA and RBPT, respectively. Milk Ring Test (MRT) was carried out only in one farm and 12.82% of the tested animals were turned positive. Culture examination analysis of milk samples, two animals revealed the presence of organisms indistinguishable from Brucel...
Source: Tropical Animal Health and Production - July 31, 2009 Category: Veterinary Research Tags: Tropical Animal Health and Production Source Type: journals

Epigallocatechin gallate ameliorates chronic fatigue syndrome in mice: Behavioral and Biochemical Evidence.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Three decades after the coining of the term chronic fatigue syndrome, the diagnosis of this illness is still symptom based and the aetiology remains elusive. Chronic fatigue syndrome pathogenesis seems to be multifactorial and the possible involvement of immune system is supported. The present study was designed to evaluate the effects of the epigallocatechin gallate in a mouse model of immunologically-induced chronic fatigue. On 19th day, after lipopolysaccharide/Brucella abortus administration, the mice showed significant increase in immobility period, post swim fatigue and thermal hyperalgesia. Behavioral deficits w...
Source: Behavioural Brain Research - July 26, 2009 Category: Neurology Authors: Sachdeva AK, Kuhad A, Tiwari V, Chopra K Tags: Behav Brain Res Source Type: journals

Investigation of the spread of brucellosis among human and animal populations in southeastern Bulgaria, 2007.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Three human cases of brucellosis were reported in summer 2007 in the region of Haskovo in southeastern Bulgaria. Subsequently, the regional veterinary and public health authorities carried out investigations to determine the spread of infection in domestic animals and in the human population. As a result, over 90,000 animals were tested, and 410 were found infected with brucellosis. The screening of 561 people believed to have been at risk of infection yielded 47 positive results. The majority of these persons had direct contact with domestic animals or had consumed unpasteurised dairy products. The investigations reve...
Source: Euro Surveill - July 24, 2009 Category: Infectious Diseases Authors: Tzaneva V, Ivanova S, Georgieva M, Tasheva E Tags: Euro Surveill Source Type: journals

Activities of Urease and Nickel Uptake of Helicobacter pylori Proteins are Media- and Host-DependentEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: H. pylori took nickel much more efficiently up than E. coli. The observed differences in urease activity are most likely due to additional protein components absent in the recombinant E. coli strain. The observed variety in nickel uptake and urease activities on the different media in the same organism depended on the intrinsic nickel content and chelating capacities of media components. Different culture conditions may lead to varying results; generalizations should be concluded only after excluding their media dependence. (Source: Helicobacter)
Source: Helicobacter - July 22, 2009 Category: Gastroenterology Authors: Lutz Wolfram, Peter Bauerfeind Tags: ORIGINAL ARTICLES Source Type: journals

Cytotoxicity of Brucella Smooth Strains for Macrophage is Mediated by Increased Secretion of Type IV Secretion System.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Some Brucella rough mutants cause cytotoxicity resembling oncosis and necrosis in macrophage. The cytotoxicity requires type IV secretion system (T4SS) and protein synthesis resulted from exposure of T4SS on the surface because of the shortened O antigen. However, whether the cytotoxicity is rough mutant unique and is really mediated by over expression of T4SS is not definitely determined. To test this, in the present study, a virB inactivation mutant (BMDeltavirB) and an over-expression strain (BM-VIR) of a smooth B. melitensis strain (BM) were constructed and their cytotoxicity for macrophage and intracellular surviv...
Source: Microbiology - July 22, 2009 Category: Microbiology Authors: Zhong Z, Wang Y, Qiao F, Wang Z, Du X, Xu J, Zhao J, Qu Q, Dong S, Sun Y, Huang L, Huang K, Chen Z Tags: Microbiology Source Type: journals

MLVA-16 typing of 295 marine mammal Brucella isolates from different animal and geographic origins identifies 7 major groups within Brucella ceti and Brucella pinnipedialisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: The clustering analysis of a large collection of marine mammal Brucella isolates from European waters significantly strengthens the current view of the population structure of these two species, and their relative position with respect to the rest of the Brucella genus. MLVA-16 is confirmed as being a rapid, highly discriminatory and reproducible method to classify Brucella strains including the marine mammal isolates. The Brucella2009 MLVA-16 genotyping database available at http://mlva.u-psud.fr/ is providing a detailed coverage of all 9 currently recognized Brucella species. (Source: BMC Microbiology - Latest articles)
Source: BMC Microbiology - Latest articles - July 19, 2009 Category: Microbiology Authors: Marianne MaquartPhilippe Le FlecheGeoffrey FosterMorten TrylandFrancoise RamisseBerit DjonneSascha Al DahoukIsabelle JacquesHeinrich NeubauerKarl WalravensJacques GodfroidAxel CloeckaertGilles Vergnaud Source Type: journals

Current Understanding of the Genetic Diversity of Brucella, an Expanding Genus of Zoonotic Pathogens.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Brucella species are responsible for brucellosis, one of the world's most widespread zoonotic diseases causing abortion in domestic animals and a potentially debilitating infection of man. Despite the identification of a number of distinct species within the genus with differing host preferences and pathogenicity it has been known for many years that members of the genus are genetically homogeneous. However since the start of the millennium the application of new technologies to the group has resulted in rapid advances in the understanding of Brucella diversity and, after many years of inactivity, a process of expansio...
Source: Infection, Genetics and Evolution - July 19, 2009 Category: Genetics & Stem Cells Authors: Whatmore AM Tags: Infect Genet Evol Source Type: journals

The role of Brucellacapt test for follow-up patients with brucellosis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The dynamic of Brucellacapt titers was evaluated in 104 patients with brucellosis with favorable outcome and in 28 patients with persistent illness duration, during the follow-up period of 15 months. In patients with favorable outcome, a permanently decreasing tendency of Brucellacapt titers was evident. Titers</=1/320 were noted in 27% and 90% of the patients, at the end of the 4th and 15th month, respectively. In patients with persistent disease, persistence or slow titre regression during the entire follow-up period was evident. Four and 15 months of the treatment, titers of 1/320 were registered in 4%, and 14%, ...
Source: Comparative immunology, microbiology and infectious diseases. - July 19, 2009 Category: Allergy & Immunology Authors: Bosilkovski M, Katerina S, Zaklina S, Ivan V Tags: Comp Immunol Microbiol Infect Dis Source Type: journals

IS711-based real-time PCR assay as a tool for detection of Brucella spp. in wild boars and comparison with bacterial isolation and serologyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The results presented here indicate that IS711 real-time PCR assay is a specific and sensitive tool for detection of Brucella spp. infections in wild boars. For this reason, we propose the employment of IS711 real-time PCR as a complementary tool in brucellosis screening programs and for confirmation of diagnosis in doubtful cases. (Source: BMC Veterinary Research - Latest articles)
Source: BMC Veterinary Research - Latest articles - July 13, 2009 Category: Veterinary Research Authors: Vladimira HinicIsabelle BrodardAndreas ThomannMilena HolubRaymond MiserezCarlos Abril Source Type: journals

Brucella cervical spondylitis complicated by spinal cord compression: a case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A case of 65-year-old farmer who presented with Brucella-related cervical spondylitis is described. Because of the advanced form of the infection resulted in neurological impairment, cervical vertebra corpectomy and debridement of the paravertebral granulomatous tissue deposits were performed followed by stabilization with anterior plating and bone grafting. In addition, double antimicrobial chemotherapy regimen was administered for 12 weeks. After one year, follow up evaluation demonstrated resolution of the infection. The authors recommend that brucellosis should be included in the differential diagnosis of cervical spon...
Source: Cases Journal - July 8, 2009 Category: Journals (General) Source Type: journals

Protection of mice from Brucella infection by immunization with attenuated Salmonellaenterica serovar typhimurium expressing A L7/L12 and BLS fusion antigen of Brucella.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study describes the potential use of attenuated Salmonella enterica serovar Typhimurium Strains (S. typhimurium) to express and deliver a L7/L12 and BLS fusion antigen of Brucella as a vaccination strategy to prevent Brucella infection in mice. S. typhimurium X4072 that contained a pTrc99A-BLS-L7/L12 plasmid, designated X4072bl, can deliver a L7/L12 and BLS fusion antigen expressed by the bacterium itself, while S. typhimurium X4550 that contained an asd-pVAX1-BLS-L7/L12 (asd-pBL) plasmid, designated X4550bl, can deliver the antigen to be expressed in target eukaryotic cells. When orally administered to BALB/c mice, b...
Source: Vaccine - July 7, 2009 Category: Allergy & Immunology Authors: Zhao Z, Li M, Luo D, Xing L, Wu S, Duan Y, Yang P, Wang X Tags: Vaccine Source Type: journals

Brucellosis presenting as a spinal epidural abscess in a 41-year-old farmer: a case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Spinal epidural abscess is a rare condition, difficult to diagnose, may be complicated by potentially disastrous neurological or vascular complications, and it can be fatal if left untreated. Patients complaining of fever and back pain, particularly in endemic areas should be investigated as possible cases of brucellosis and MRI is the method of first choice in the diagnostic process. Neurological dysfunction is often disproportionate to the observed degree of compression. A delay in diagnosis or surgical treatment may result in deleterious sequelae such as permanent paralysis or even death for patients with sp...
Source: Cases Journal - July 1, 2009 Category: Journals (General) Source Type: journals

Fever in returned travellers presenting in the United Kingdom: Recommendations for investigation and initial managementEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Summary: International travel is increasing. Most physicians and general practitioners will encounter returned travellers with fever and the majority of travel-related infection is associated with travel to the tropics. In those returning from the tropics malaria must always be excluded, and HIV considered, from all settings. Common causes of non-malarial fever include from Africa rickettsial diseases, amoebic liver abscess and Katayama syndrome; from South and South East Asia, enteric fever and arboviral infection; from the Middle East, brucellosis and from the Horn of Africa visceral leishmaniasis. Other rare but importa...
Source: Journal of Infection - June 30, 2009 Category: Infectious Diseases Authors: Victoria Johnston, Jane M. Stockley, David Dockrell, David Warrell, Robin Bailey, Geoffrey Pasvol, John Klein, Andrew Ustianowski, Michael Jones, Nicholas J. Beeching, Michael Brown, Ann L.N. Chapman, Frances Sanderson, Christopher J.M. Whitty, On behalf Tags: Review Source Type: journals

Seroprevalence of Brucella agglutinins: a pilot study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19680003 [PubMed - in process] (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - June 30, 2009 Category: Pathology Authors: Nagarathna S, Sharmada S, Kumari HB, Arvind N, Sundar P, Sangeetha S Tags: Indian J Pathol Microbiol Source Type: journals