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Bupropion: Delirium in a patient with bipolar disorder: case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Reactions)
Source: Reactions - November 16, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals

Incidence and onset of delayed seizures after overdoses of extended-release bupropion. - Starr P, Klein-Schwartz W, Spiller H, Kern P, Ekleberry SE, Kunkel S.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study systematically evaluates the frequency and timing of seizures and an association between other toxic effects (ie, agitation, tremors, and hallucin... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - November 15, 2009 Category: Global & Universal Tags: Poisoning Source Type: info

The Cost-Effectiveness of an Extended Course (12 + 12 Weeks) of Varenicline Compared with Other Available Smoking Cessation Strategies in the United States: An Extension and Update to the BENESCO ModelEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: A total of 12 weeks of varenicline followed by a further 12-week course for successful quitters is a highly cost-effective alternative compared with currently available smoking cessation options. (Source: Value in Health)
Source: Value in Health - November 14, 2009 Category: Global & Universal Authors: Chris Knight, Paul Howard, Christine L. Baker, Jeno P. Marton Source Type: journals

BUPROPION (Bupropion Hydrochloride) Tablet, Extended Release [Physicians Total Care, Inc.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Updated Date: Nov 10, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - November 10, 2009 Category: Drugs & Pharmacology Source Type: organizations

Repeated medication-assisted smoking cessation may be effectiveEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: Arch Internal Med Area: News A case series report suggests that smokers who fail to quit after one cycle of pharmacotherapy may benefit from repeated cycles. The authors note that while controlled trials show benefit in improving quit rates in smokers using cessation therapy, many will not be successful on the first attempt and there is little published information on the outcome of subsequent attempts. They therefore followed a cohort of smokers who were offered up to four courses of pharmacotherapy for smoking cessation over a two year period. The cohort was recruited from rural primary car...
Source: NeLM - Mental Health - November 10, 2009 Category: Psychiatry Source Type: organizations

Addition of psychotherapy to medication in patients with inadequate response to antidepressants no better than optimisation of pharmacotherapy?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: Arch Gen Psychiatry Area: News The results of a study (REVAMP trial) designed to evaluate the effects of adding psychotherapy to medication in patients with chronic depression not responding adequately to a trial of antidepressants has been published in the Archives of General Psychiatry. The trial included chronically depressed patients with a major depressive episode (according to DSM-IV criteria) who had persistent depressive symptoms for more than two years. There were two 12-week phases. During phase 1 (n=808), patients were assigned to receive an antidepressant according to an al...
Source: NeLM - News - November 3, 2009 Category: Drugs & Pharmacology Source Type: organizations

Nicotine patch plus lozenge best for smoking cessation?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: Arch Gen Psychiatry Area: News The results of a randomised, placebo-controlled trial evaluating the relative efficacies of nicotine lozenges, nicotine patches, bupropion, nicotine patches plus nicotine lozenges, and bupropion plus nicotine lozenges in smoking cessation has been published in the Archives of General Psychiatry. A total of 1,504 adult smokers were recruited into this US study; all smoked an average of ?10 cigarettes per day for at least the past 6 months and were motivated to quit smoking. Those using any other form of tobacco, currently taking bupropion, or with a current psychosis ...
Source: NeLM - News - November 3, 2009 Category: Drugs & Pharmacology Source Type: organizations

ORIGINAL ARTICLE: A Randomized Placebo-Controlled Clinical Trial of 5 Smoking Cessation PharmacotherapiesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion While the nicotine lozenge, bupropion, and bupropion plus lozenge produced effects that were comparable with those reported in previous research, the nicotine patch plus lozenge produced the greatest benefit relative to placebo for smoking cessation. (Source: Archives of General Psychiatry)
Source: Archives of General Psychiatry - November 2, 2009 Category: Psychiatry Authors: Piper, M. E., Smith, S. S., Schlam, T. R., Fiore, M. C., Jorenby, D. E., Fraser, D., Baker, T. B. Tags: Psychiatry, Psychopharmacology, Public Health, Tobacco, Randomized Controlled Trial, Drug Therapy, Drug Therapy, Other Original Article Source Type: journals

A Randomized Placebo-Controlled Clinical Trial of 5 Smoking Cessation Pharmacotherapies [Original Article]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion While the nicotine lozenge, bupropion, and bupropion plus lozenge produced effects that were comparable with those reported in previous research, the nicotine patch plus lozenge produced the greatest benefit relative to placebo for smoking cessation. (Source: Archives of General Psychiatry)
Source: Archives of General Psychiatry - November 2, 2009 Category: Psychiatry Authors: Piper, M. E., Smith, S. S., Schlam, T. R., Fiore, M. C., Jorenby, D. E., Fraser, D., Baker, T. B. Tags: Psychiatry, Psychopharmacology, Public Health, Tobacco, Randomized Controlled Trial, Drug Therapy, Drug Therapy, Other Original Article Source Type: journals

Combination Smoking Cessation Therapy Increases Abstinence Rates in TeensEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The first study of combination therapy of bupropion SR and contingency management for smoking cessation in adolescents suggests that a combination of the 2 is superior to either treatment alone. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 2, 2009 Category: Consumer Health News Tags: Psychiatry Source Type: news

Treatment for SRI-Linked Sex Problems StudiedEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
SANTA FE, N.M. — Skip the yohimbe. Don't switch your patients to bupropion, and don't tell them to stop taking their antidepressants before the weekend. Men and women who develop sexual dysfunction while on serotonin reuptake inhibitors (SRIs) should be treated with phosphodiesterase-5 (PDE-5) inhibitors, Dr. H. George Nurnberg told attendees at an annual psychiatric symposium sponsored by the University of Arizona. He dismissed as “clinical folklore” virtually all the commonly used remedies for sexual dysfunction associated with SRIs. (Source: Ob.Gyn. News)
Source: Ob.Gyn. News - November 1, 2009 Category: OBGYN Authors: JANE SALODOF MacNEIL Tags: Clinical Rounds Source Type: journals

The Roles of Dopamine Transport Inhibition and Dopamine Release Facilitation in Wake Enhancement and Rebound Hypersomnolence Induced by Dopaminergic AgentsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: All DA releasing agents tested, and some DAT-inhibiting agents, produced RHS at equal wake-promoting doses. Thus amphetamine-like DA release appears sufficient for inducing RHS, but additional properties (pharmacologic and/or pharmacokinetic) evidently underlie RHS of other DAT inhibitors. Enhancing wake while mitigating RHS can be achieved by combining DAT-inhibiting and DA-releasing agents. Keywords: Sleep/wake, dopamine transporter, amphetamine, hypersomnolence, pharmacokinetic, rat (Source: Sleep)
Source: Sleep - October 31, 2009 Category: Sleep Medicine Source Type: journals

Gestational Exposure to Antidepressants and the Risk of Spontaneous Abortion: A Review.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. This review suggests that gestational exposure to antidepressants, especially paroxetine and venlafaxine, can lead to spontaneous abortion. PMID: 19863482 [PubMed - as supplied by publisher] (Source: Current Drug Delivery)
Source: Current Drug Delivery - October 29, 2009 Category: Drugs & Pharmacology Authors: Broy P, Bérard A Tags: Curr Drug Deliv Source Type: journals

Effects of Treatment for Tobacco Dependence on Resting Cerebral Glucose MetabolismEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
& Arthur L Brody Keywords: tobacco dependence, nicotine, cigarette, 18F-fluorodeoxyglucose–positron emission tomography (FDG–PET), statistical parametric mapping, bupropion HCl (Source: Neuropsychopharmacology)
Source: Neuropsychopharmacology - October 28, 2009 Category: Neurology Authors: Matthew R CostelloMark A MandelkernStephen ShoptawStephanie ShulenbergerStephanie K BakerAnna L AbramsCatherine XiaEdythe D LondonArthur L Brody Source Type: journals

Orexigen Therapeutics Releases New Efficacy Data for Contrave(R) in Late Breaker Presentations at the 27th Annual Scientific Meeting of The Obesity SocietyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
SAN DIEGO, October 27, 2009 /PRNewswire-FirstCall/ -- Orexigen(R) Therapeutics, Inc. today announced results from new intent to treat (ITT) analyses from the COR-I and COR-II Phase 3 trials of Contrave(R) (naltrexone SR/bupropion SR), the first... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - October 27, 2009 Category: Pharmaceuticals Source Type: clinical trials

A randomised trial of glucose tablets to aid smoking cessationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions No significant effect of glucose tablets over and above sweet tasting tablets could be detected overall, but the possibility of an effect as an adjunct to NRT or bupropion merits further investigation. Content Type Journal ArticleCategory Original InvestigationDOI 10.1007/s00213-009-1692-3Authors Robert West, University College London Cancer Research UK Health Behaviour Research Centre, Department of Epidemiology and Public Health London WC1E 6BT UKSylvia May, University College London Health Behaviour Research Centre London UKAndy McEwen, University College London Health Behaviour Research...
Source: Psychopharmacology - October 26, 2009 Category: Psychiatry Tags: Psychopharmacology Source Type: journals

BUPROPION (Bupropion Hydrochloride) Tablet, Extended Release [Physicians Total Care, Inc.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Updated Date: Oct 26, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - October 26, 2009 Category: Drugs & Pharmacology Source Type: organizations

BUPROPION HYDROCHLORIDEtablet, Film Coated [Contract Pharmacy Services-PA]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Updated Date: Oct 22, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - October 22, 2009 Category: Drugs & Pharmacology Source Type: organizations

Comparison of Combined Bupropion and Naltrexone Therapy for Obesity with Monotherapy and Placebo.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: NB caused gradual sustained weight loss over 48 wk; NB32 and NB16 demonstrated greater weight loss in the intent-to-treat population due to lower attrition rates. Further study is needed to demonstrate long-term efficacy and safety of NB. PMID: 19846734 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - October 20, 2009 Category: Endocrinology Authors: Greenway FL, Dunayevich E, Tollefson G, Erickson J, Guttadauria M, Fujioka K, Cowley MA, Tags: J Clin Endocrinol Metab Source Type: journals

BUPROPION HYDROCHLORIDEtablet, Film Coated [Sandoz Inc]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Updated Date: Oct 20, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - October 20, 2009 Category: Drugs & Pharmacology Source Type: organizations

Synthesis and Biological Evaluation of Bupropion Analogues as Potential Pharmacotherapies for Cocaine AddictionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - October 12, 2009 Category: Chemistry Tags: article Source Type: journals

Varenicline and suicidal behaviour: a cohort study based on data from the General Practice Research Database. - Gunnell D, Irvine D, Wise L, Davies C, Martin RM.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
OBJECTIVE: To determine whether varenicline, a recently licensed smoking cessation product, is associated with an increased risk of suicide and suicidal behaviour compared with alternative treatments bupropion and nicotine replacement therapy. DESIGN: Coho... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - October 11, 2009 Category: Global & Universal Tags: Home and Consumer Product Safety Source Type: info

WELLBUTRIN (Bupropion Hydrochloride) Tablet, Film Coated [SmithKline Beecham Corporation]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Updated Date: Oct 9, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - October 9, 2009 Category: Drugs & Pharmacology Source Type: organizations

Intravenous Lipid Emulsion as Antidote (review)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Available data, though limited, suggest that ILE may be beneficial in treating life-threatening cardiotoxicity induced by highly lipophilic drugs. Physicians managing these cases should follow established guidelines and consult at an early stage with a poison center. (66 references) COMMENT: This thoughtful review is well worth reading. Although ILE is not yet ready for routine use in the early stages of resuscitation, many toxicologists would recommend it as a last-ditch effort when a lipophilic drug has caused cardiovascular collapse not improved by standard treatment. The strongest statement to this ...
Source: The Poison Review - October 2, 2009 Category: Toxicology Authors: Leon Tags: Medical antidote intravenous lipid emulsion Source Type: info

Varenicline and suicidal behaviour: a cohort study based on data from the General Practice Research DatabaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: BMJ Area: News According to the authors of a cohort study published early online in the British Medical Journal, an increased risk of self-harm with varenicline cannot be ruled out. They do note however that their results 'provide some reassurance concerning its association with suicidal behaviour'. The MHRA issued a warning in December 2007, after reports of depression and suicidal thoughts among people prescribed varenicline; further warnings were issued in July and November 2008. Similar warnings have been issued by regulatory authorities worldwide, and the US FDA recently required the ma...
Source: NeLM - News - October 1, 2009 Category: Drugs & Pharmacology Source Type: organizations

Chantix-Suicide Link QuestionedEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Earlier this year, the FDA ordered a "black box" warning be added to the drugs Chantix (varenicline) and Zyban (bupropion), which are both used as aids in quitting smoking. ... (Source: About.com Depression)
Source: About.com Depression - October 1, 2009 Category: Psychiatry Source Type: consumer

Smoking Cessation Strategies Now Numerous: Try nicotine replacement therapy plus bupropion or high-dose NRT plus nicotine gum or lozenges.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
ESTES PARK, COLO. — Three major drug classes with diverse mechanisms of action are now approved for smoking cessation, providing an unprecedented array of options in terms of sequential and combination therapies. (Source: Clinical Psychiatry News)
Source: Clinical Psychiatry News - September 30, 2009 Category: Psychiatry Authors: BRUCE JANCIN Tags: Addiction Psychiatry Source Type: journals

Crossing Borders: Factors Affecting Differences in Cost-Effectiveness of Smoking Cessation Interventions between European CountriesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Although all INMBs were positive, there were significant differences across countries. These were primarily related to choice of discount rate and epidemiology of diseases. (Source: Value in Health)
Source: Value in Health - September 24, 2009 Category: Global & Universal Authors: Pepijn Vemer, Maureen P.M.H. Rutten-van Mölken Source Type: journals

Incidence and onset of delayed seizures after overdoses of extended-release bupropionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Delayed seizure onset suggests a minimum observation period of 24 hours after bupropion XL overdose. Although patients experiencing agitation or tremors may be at greater risk, seizures can occur without preceding central nervous system toxicity. (Source: The American Journal of Emergency Medicine)
Source: The American Journal of Emergency Medicine - September 24, 2009 Category: Emergency Medicine Authors: Paul Starr, Wendy Klein-Schwartz, Henry Spiller, Perri Kern, Susan E. Ekleberry, Susan Kunkel Tags: Original Contributions Source Type: journals

Efficacy of pharmacotherapies for short-term smoking abstinence: A systematic review and meta-analysis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Background: Smoking cessation has important immediate health benefits. The comparative short-term effectiveness of smoking cessation interventions is not well known. We aimed to determine the relative effectiveness of nicotine replacement therapy (NRT), bupropion and varenicline at 4 weeks post-target quit date. Methods: We searched 10 electronic medical databases (inception to October 2008). We selected randomized clinical trials [RCTs] evaluating interventions for our primary outcome of abstinence from smoking at at-least 4 weeks post-target quit date, with biochemical confirmation. We conducted random-effects odds ratio...
Source: Harm Reduction Journal - September 17, 2009 Category: Drugs & Pharmacology Authors: Edward MillsPing WuDean SpurdenJon EbbertKumanan Wilson Source Type: journals

Bupropion and nicotine enhance responding for nondrug reinforcers via dissociable pharmacological mechanisms in ratsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion The reinforcement enhancing effects of nicotine and bupropion increased over time and repeated treatments suggesting a shared mechanism of action. However, the reinforcement enhancing effects of nicotine are mediated by nicotinic acetylcholine receptors, whereas the reinforcement enhancing effects of bupropion were mediated by alpha noradrenergic receptors. Content Type Journal ArticleCategory Original InvestigationDOI 10.1007/s00213-009-1666-5Authors Matthew I. Palmatier, Kansas State University Department of Psychology 469 Bluemont Hall Manhattan KS 66502 USAMelissa E. Levin, University o...
Source: Psychopharmacology - September 17, 2009 Category: Psychiatry Tags: Psychopharmacology Source Type: journals

Comparative benefits and harms of competing medications for adults with attention-deficit hyperactivity disorder: a systematic review and indirect comparison meta-analysisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: DARE Area: Evidence > Disease Focused Reviews CRD Summary: This generally well-conducted review assessed the efficacy and safety of treatments for attention-deficit hyperactivity disorder in adults. The authors concluded that the use of immediate release methylphenidate as a first-line treatment was supported. The questionable quality of many of the included studies and some concerns over the appropriateness of the synthesis may mean these conclusions were overstated. [Studies of the following treatments were eligible: amphetamine mixture, dextroamphetamine sulphate, methylphenidate HCl, dexmethylphenidate HCl, ...
Source: NeLM - Disease Focused Reviews - September 14, 2009 Category: Internal Medicine Source Type: organizations

Predicting adherence to treatment for methamphetamine dependence from neuropsychological and drug use variablesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Although some individuals who abuse methamphetamine have considerable cognitive deficits, no prior studies have examined whether neurocognitive functioning is associated with outcome of treatment for methamphetamine dependence. In an outpatient clinical trial of bupropion combined with cognitive behavioral therapy and contingency management (Shoptaw, S., Heinzerling, K.G., Rotheram-Fuller, E., Steward, T., Wang, J., Swanson, A.N., De La Garza, R., Newton, T., Ling, W., 2008. Randomized, placebo-controlled trial of bupropion for the treatment of methamphetamine dependence. Drug Alcohol Depend 96, 222-232.), 60 met...
Source: Drug and Alcohol Dependence - September 14, 2009 Category: Addiction Authors: Andy C. Dean, Edythe D. London, Catherine A. Sugar, Christina M.R. Kitchen, Aimee-Noelle Swanson, Keith G. Heinzerling, Ari D. Kalechstein, Steven Shoptaw Tags: Full length reports Source Type: journals

[Care Results in a Specialist Stop-Smoking Unit.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: A stop-smoking clinic that is designed according to SEPAR Recommendations is effective and has a good cost/effective ratio. PMID: 19758742 [PubMed - as supplied by publisher] (Source: Archivos de Bronconeumologia)
Source: Archivos de Bronconeumologia - September 13, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Jiménez Ruiz CA, Mayayo Ulibarri M, Cicero Guerrero A, Amor Besada N, Ruiz Martín JJ, Cristóbal Fernández M, Astray Mochales J Tags: Arch Bronconeumol Source Type: journals

UCLA researchers develop biomarker for rapid relief of major depressionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
It is a long, slow slog to treat major depression. Many antidepressant medications are available, but no single biomarker or diagnostic test exists to predict which one is right for an individual. As a result, for more than half of all patients, the first drug prescribed doesn't work, and it can take months to figure out what does. Now, based on the final results of a nationwide study led by UCLA, clinicians may be able to accurately predict within a week whether a particular drug will be effective by using a non-invasive test that takes less than 15 minutes to administer. The test will allow physicians to quickly switch ...
Source: UCLA Newsroom: Health Sciences - September 10, 2009 Category: Universities & Medical Training Source Type: organizations

Low-Dose Buspirone, Melatonin and Low-Dose Bupropion Added to Mood Stabilizers for Severe Treatment-Resistant Bipolar DepressionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Psychother Psychosom 2009;78:391-393 (DOI:10.1159/000235985) (Source: Karger Publishers)
Source: Karger Publishers - September 7, 2009 Category: Cancer & Oncology Source Type: journals

Effectiveness of a quantitative electroencephalographic biomarker for predicting differential response or remission with escitalopram and bupropion in major depressive disorderEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We examined the Antidepressant Treatment Response (ATR) index as a predictor of differential response and remission to escitalopram, bupropion, or a combination of the two medications, in subjects with major depressive disorder (MDD). Three hundred seventy-five subjects had a baseline quantitative electroencephalographic (QEEG) study preceding 1 week of treatment with escitalopram, 10 mg, after which a second QEEG was performed and the ATR index was calculated. Subjects then were randomized to continue escitalopram, switch to bupropion, or receive a combination of the two. Clinical response was assessed using the 17-item H...
Source: Psychiatry Research - September 7, 2009 Category: Psychiatry Authors: Andrew F. Leuchter, Ian A. Cook, William S. Gilmer, Lauren B. Marangell, Karl S. Burgoyne, Robert H. Howland, Madhukar H. Trivedi, Sidney Zisook, Rakesh Jain, Maurizio Fava, Dan Iosifescu, Scott Greenwald Tags: Articles Source Type: journals

Bupropion-Induced Neck and Shoulder PainEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Pharmacopsychiatry 2009; 42: 203-204DOI: 10.1055/s-0029-1220934© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents | Full text (Source: Pharmacopsychiatry)
Source: Pharmacopsychiatry - September 2, 2009 Category: Psychiatry Tags: Letter Source Type: journals

Cost Effectiveness of Varenicline in Belgium, Compared with Bupropion, Nicotine Replacement Therapy, Brief Counselling and Unaided Smoking Cessation: A BENESCO Markov Cost-Effectiveness AnalysisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Clinical Drug Investigation)
Source: Clinical Drug Investigation - September 1, 2009 Category: Drugs & Pharmacology Authors: Annemans, LievenNackaerts, KristiaanBartsch, PierrePrignot, JacquesMarbaix, Sophie Tags: Original Research Articles Source Type: journals

Recalls and Safety Alerts: Warning on Neuropsychiatric Effects from Smoking Cessation DrugsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
FDA is requiring that two drugs used to help people stop smoking carry new warnings about the risk of serious neuropsychiatric effects. The drugs are Chantix (varenicline) and Zyban (bupropion). The same warnings will be required for other bupropio... (Source: Food and Drug Adminstration (FDA): Patient Safety News)
Source: Food and Drug Adminstration (FDA): Patient Safety News - September 1, 2009 Category: American Health Source Type: news

Significant Weight Loss Shown With Naltrexone/Bupropion ComboEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
NEW ORLEANS — An investigational oral agent that combines naltrexone and bupropion produced clinically meaningful weight loss at 56 weeks, results from a multicenter phase III trial showed. (Source: Cardiology News)
Source: Cardiology News - August 31, 2009 Category: Cardiology Authors: DOUG BRUNK Tags: Epidemiology & Prevention Source Type: news

WELLBUTRIN (Bupropion Hydrochloride) Tablet, Film Coated [SmithKline Beecham Corporation]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Updated Date: Aug 31, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - August 31, 2009 Category: Drugs & Pharmacology Source Type: organizations

Substrate Specificity, Regulation, and Polymorphism of Human Cytochrome P450 2B6.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CYP2B6 is mainly expressed in the liver that has been thought historically to play an insignificant role in human drug metabolism. However, increased interest in this enzyme has been stimulated by the discovery of polymorphic and ethnic differences in CYP2B6 expression, identification of additional substrates for CYP2B6, and evidence for co-regulation with CYP3A4. This paper updates our knowledge about the structure, function, regulation and polymorphism of CYP2B6. CYP2B6 can metabolise approximately 8% of clinically used drugs (n > 60), including cyclophosphamide, ifosfamide, tamoxifen, ketamine, artemisinin, nevir...
Source: Current Drug Metabolism - August 27, 2009 Category: Drugs & Pharmacology Authors: Mo SL, Liu YH, Duan W, Wei MQ, Kanwar JR, Zhou SF Tags: Curr Drug Metab Source Type: journals

Table of ContentsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Transdermal Methylphenidate Absorption Differs Based on Patch's Application SiteBipolar Youths Receiving Mood Stabilizers Show Some Cognitive Impairments in StudyMethylphenidate Side Effects in Childhood Cancer SurvivorsQuetiapine Equal to Placebo for Teen Bipolar DepressionADHD Treatment: Duration of Action of LisdexamfetamineAripiprazole Assessed for Bipolar Disorder Comorbid With ADHDControlled Atomoxetine Trial for ADHD Children in RussiaPregabalin for Treating Dysautonomic CrisisAripiprazole for Psychosis in a Child With Arachnoid CystBlack Box Warnings for Bupropion and VareniclineAtomoxetine Safety Labeling Changes ...
Source: The Brown University Child & Adolescent Psychopharmacology Update - August 21, 2009 Category: Psychiatry Source Type: journals

Saudi bans anti-smoking drugsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Saudi Arabia's Ministry of Health has banned two popular smoking cessation drugs as their side-effects include suicidal tendencies, the Saudi Gazette has reported. The drugs containing varenicline, with the trade name of Champix from Pfizer, and Bupropion were banned after the US Food and Drugs Administration (FDA) had issued a black box warning, the toughest warning on risks associated with a medicine, on serious mental health risks of the drugs. (Source: Healthcare)
Source: Healthcare - August 17, 2009 Category: Middle East Health Source Type: info

I'm new here, I'm looking for understanding and adviseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Author: Diary of a Quitter Posted: Sat Aug 15, 2009 11:32 am Hmm...It's funny you should mention that Matt. I also take bupropion, but for depression. Perhaps that influenced my ability to quit smoking and stay quit this time. I smoked from age 13 to 29 when I got pregnant. I quit, then picked it up again after my daughter was 2 or so - when I went back to school. My partner had quit for the most part too, and since we had a kid we didn't allow smoking in the house or in the car. Living in a place where it's cold and rainy 9 months of the year doesn't make it real ...
Source: Suboxone Forum - August 15, 2009 Category: Addiction Source Type: forums

Effects of bupropion augmentation on pro-inflammatory cytokines in escitalopram-resistant patients with major depressive disorderEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
AbstractStudies so far have provided contradictory results on immune system markers during use of antidepressants. There are no data on changes in immune parameters after treatment augmentation. The present study aimed to clarify whether the addition of bupropion in escitalopram-resistant patients with major depression causes changes in the immune system and whether treatment response could be predicted by baseline levels of cytokines. We recruited 28 depressive patients (11 men and 17 women) who did not respond to 12-week treatment with escitalopram (20 mg/d) for an augmentation trial with bupropion (150–300&nb...
Source: Journal of Psychopharmacology - August 13, 2009 Category: Psychiatry Authors: Eller, T, Vasar, V, Shlik, J, Maron, E Tags: Article Source Type: journals

Use Generic Zyban to Quit Unhealthy Habit of SmokingEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Generic Zyban is the smoking cessation drug that helps the smokers to quit the unhealthy habit of smoking. Generic Zyban contains Bupropion as an active constituent that helps the person to overcome the unhealthy habit of smoking. It reduces the person urge to smoke. The habit of smoking is hard to... (Source: Networks Talk)
Source: Networks Talk - August 12, 2009 Category: UK Health Authors: Victor Bush Source Type: organizations

Sexual side-effects of contemporary antidepressants: review.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The aim of the present study was to review the sexual side-effects of contemporary antidepressants in Australia, comparing the selective serotonin re-uptake inhibitors (SSRIs) with venlafaxine, reboxetine, mirtazepine, duloxetine, bupropion, desvenlafaxine and agomelatine. Double-blind, randomized comparative studies of these antidepressants that included assessment of sexual dysfunction with validated rating scales in patients with major depressive disorder were identified from the literature using MEDLINE, EMBASE and PsychINFO databases. Bupropion and duloxetine caused significantly less sexual dysfunction than the S...
Source: The Australian and New Zealand Journal of Psychiatry - August 12, 2009 Category: Psychiatry Authors: Schweitzer I, Maguire K, Ng C Tags: Aust N Z J Psychiatry Source Type: journals

Racial differences in smoking abstinence rates in a multicenter, randomized, open-label trial in the United StatesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Regardless of the treatment used, minority smokers in the US have lower smoking abstinence after treatment for tobacco dependence. Future research should focus on the improvement in treatment strategies for minority smokers. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s10389-009-0277-2Authors Ivana T. Croghan, Mayo Clinic College of Medicine 200 First Street SW Rochester MN 55905 USARichard D. Hurt, Mayo Clinic College of Medicine 200 First Street SW Rochester MN 55905 USAJon O. Ebbert, Mayo Clinic College of Medicine 200 First Street SW Rochester MN 55905 USAGary A. Cro...
Source: Journal of Public Health - August 11, 2009 Category: Health Management Tags: Journal of Public Health Source Type: journals