Pediatric early-phase anorexia nervosa without hypokalemia exhibiting acute tubular injury: a case report
AbstractAnorexia nervosa can lead to kidney complications. Few studies reported kidney biopsy results in young adults, most of whom had chronic anorexia nervosa, and kidney biopsy findings in pediatric patients with early-phase anorexia nervosa are rarely reported. A 14-year-old girl who lost weight due to excessive exercise and reduced diet was admitted for kidney dysfunction. She was 147 cm tall and weighed 32.9 kg, with a body mass index of 15.2 kg/m2. She was 39 kg about a year earlier. Her heart rate and blood pressure were 30–40 beats/min and 108/68 mmHg, respectively. She had kidney dysfunction (estimated g...
Source: CEN Case Reports - April 24, 2024 Category: Urology & Nephrology Source Type: research
Renal tubular necrosis associated with anagrelide administration: a case report
AbstractA 62-year-old female patient with essential thrombocythemia experienced rapid renal dysfunction and was subsequently referred to our hospital. Further investigations did not reveal any significant abnormalities except for a slight increase in urinary β2-microglobulin levels. A renal biopsy was performed to investigate the cause of her renal dysfunction, revealing acute tubular necrosis, interstitial edema, and arteriosclerosis. No significant glomerular lesions were observed. Immunofluorescence staining and electron microscopy showed no abnorma lities. She had been using anagrelide for 4 years, and her dosage was...
Source: CEN Case Reports - April 24, 2024 Category: Urology & Nephrology Source Type: research
Correction to: Two acute kidney injury episodes after ICI therapy: a case report
(Source: CEN Case Reports)
Source: CEN Case Reports - April 24, 2024 Category: Urology & Nephrology Source Type: research
Early diagnosis of tuberculous peritonitis in peritoneal dialysis patients using the T-SPOT test
AbstractA 49-year-old man was admitted with peritonitis nine months after starting continuous ambulatory peritoneal dialysis (CAPD) for kidney failure. Ceftazidime and cefazolin were started. Peritoneal dialysate culture was negative for bacteria, but antibiotic treatment was continued because peritonitis improved. Twenty days later, the patient was discharged with no signs of peritonitis. However, 40-day culture of the original peritoneal dialysate detectedMycobacterium tuberculosis, and peritonitis recurred, leading to readmission. A T-SPOT test was performed and was positive in 4 days. Anti-tuberculosis therapy was st...
Source: CEN Case Reports - April 21, 2024 Category: Urology & Nephrology Source Type: research
A case report and literature review of IgA nephropathy presenting as nephrotic syndrome in polycythemia vera
AbstractA 66-year-old non-smoker presented with a 2-week history of new-onset pedal oedema and gross haematuria. On evaluation, he was found to be hypertensive and oedematous with a haemoglobin of 19.1 g/dl, platelet count of 546,000/mm3, and creatinine of 2.6 mg/dl. Urine examination revealed abundant RBCs with 3+ albumin on three separate occasions. His 24-h urine protein level was 3830 mg/day, with a serum cholesterol level of 303 mg/dl. Secondary erythrocytosis and thrombocytosis tests were negative. Bone marrow examination revealed hypercellulari ty, erythroid hyperplasia, tight clusters of large megakaryocytes,...
Source: CEN Case Reports - April 21, 2024 Category: Urology & Nephrology Source Type: research
Distal renal tubular acidosis as a rare complication of vesicoureteral reflux in children: a case report and literature review
In conclusion, the development of hypokalemia and nephrolithiasis/nephrocalcinosis along with metabolic acidosis in a patient diagnosed with VUR should be considered as an indicator of impaired tubular functions. Also, the possibility of an underlying VUR in the p resence of recurrent urinary tract infection in a patient diagnosed with dRTA should not be ignored. (Source: CEN Case Reports)
Source: CEN Case Reports - April 18, 2024 Category: Urology & Nephrology Source Type: research
Gitelman syndrome and in vitro fertilization-embryo transfer: advancing preconception care in nephrology
In conclusion, preconception care and cooperation between internal medicine and obstetrics led to an excellent and successful delivery of an IVF fetus in an older patient with GS. There are no guidelines for electrolyte disorders in pregnancy, and only a few studies have reported on GS during pregnancy, including detailed postpartum assessments. (Source: CEN Case Reports)
Source: CEN Case Reports - April 17, 2024 Category: Urology & Nephrology Source Type: research
Obstructive uropathy complicated by acute aortic dissection
(Source: CEN Case Reports)
Source: CEN Case Reports - April 13, 2024 Category: Urology & Nephrology Source Type: research
Retraction Note: Anaphylaxis secondary to citric acid allergy in End Stage Renal Disease patient
(Source: CEN Case Reports)
Source: CEN Case Reports - April 9, 2024 Category: Urology & Nephrology Source Type: research
Acute oxalate nephropathy: exploring the role of excess dietary oxalate intake
We report here two cases presenting as unexplained AKI which were confirmed histologically to be due to acute oxalate nephropathy. Dietary oxalate or its precursor vitamin C was the cause of oxalate exposure in both of these cases. While one patient recovered, another continued to need dialysis and succumbed to underlying metastatic cancer. This cause should be suspected in all patients presenting with unexplained AKI, and detailed history about dietary intake of oxalate or vitamin C should be inquired. (Source: CEN Case Reports)
Source: CEN Case Reports - April 8, 2024 Category: Urology & Nephrology Source Type: research
Secondary infertility due to necrospermia in men with autosomal-dominant polycystic kidney disease: a report of two cases
We report two cases of secondary infertility in men with ADPKD. These men experienced an inability to reproduce naturally after the previous birth of a child, suggesting a progressive deterioration of semen quality. Semen analysis showed necrospermia in both patients, and transrectal ultrasound revealed marked dilatation of the seminal vesicles bilaterally. The main cause of secondary infertility in male patients with ADPKD is sperm death resulting from progressive dilatation of seminal vesicles. Further research is needed on the appropriate follow-up schedule for men with ADPKD who desire to reproduce naturally. (Source: CEN Case Reports)
Source: CEN Case Reports - April 8, 2024 Category: Urology & Nephrology Source Type: research
Nephronophthisis 13 caused by WDR19 variants with pancytopenia: case report
We present a case of nephronophthisis 13 that resulted fromWDR19 variants. The patient, a nine-year-old Japanese boy, had detection of mild proteinuria during a school urine screening. Urinalysis revealed mild proteinuria without hematuria. Blood tests indicated pancytopenia, mild elevation of liver enzymes, and kidney dysfunction. Ultrasound examination disclosed hepatosplenomegaly. Abdominal computed tomography and bone marrow assessments ruled out malignant tumors. Subsequent kidney and liver biopsies suggested nephronophthisis and congenital hepatic fibrosis. Furthermore, comprehensive genetic analysis through next-gen...
Source: CEN Case Reports - April 8, 2024 Category: Urology & Nephrology Source Type: research
Peritoneal dialysis-associated infection caused by Mycobacterium abscessus in a pediatric patient on continuous peritoneal dialysis without switching to hemodialysis
AbstractMost peritoneal dialysis (PD)-associated infections caused byMycobacterium abscessus (M. abscessus) require a transfer from PD to hemodialysis (HD). Here, we report a pediatric case of exit-site and tunnel infections caused byM. abscessus, for whom PD was continued with catheter replacement, debridement of the infected site, and the administration of multiple antibacterial agents. A 10-year-old boy with end-stage kidney disease secondary to juvenile nephronophthisis withNPHP1 deletion, for whom PD was initiated at the age of 9 years, was admitted to the hospital with complaints of fever, pus at the exit-site of t...
Source: CEN Case Reports - April 6, 2024 Category: Urology & Nephrology Source Type: research
RETRACTED ARTICLE: Anaphylaxis secondary to citric acid allergy in End Stage Renal Disease patient
AbstractDialysis reactions are not uncommon in End Stage Renal Disease (ESRD) patients who are undergoing in-center hemodialysis. Here we report the first case of anaphylaxis related to citric acid solutions used for dialysis machine disinfection and descaling. The patient developed repeated episodes of anaphylactic reactions during hemodialysis only in the inpatient setting leading to respiratory failure needing intubation and anaphylactic shock. This had failed to resolve despite using various combinations of different dialysis machines and dialyzer membranes and only resolved after the elimination of citric acid from th...
Source: CEN Case Reports - April 1, 2024 Category: Urology & Nephrology Source Type: research
A case of a peritoneal dialysis patient with left pleuroperitoneal communication caused by a pericardial defect after coronary artery bypass surgery
AbstractA 74-year-old woman with reduced kidney and cardiac function and a history of coronary artery bypass surgery involving the gastroepiploic artery to the right coronary artery and posterior descending artery #4 presented with dyspnea on exertion. Shortly after the induction of peritoneal dialysis (PD), an increase in the left pleural effusion was observed, and a diagnosis of left pleuroperitoneal communication was made by puncture drainage. The pleuroperitoneal communication hole was not detected under thoracoscopic observation; however, a 10 mm-sized hole in the pericardium was found, confirming leakage of ICG-loa...
Source: CEN Case Reports - March 31, 2024 Category: Urology & Nephrology Source Type: research
