Effects of esketamine nasal spray on depressive symptom severity in adults with treatment-resistant depression and associations between the Montgomery- Åsberg Depression Rating Scale and the 9-item Patient Health Questionnaire
CONCLUSIONS: In adults with TRD, ESK + OAD significantly improved severity of depressive symptoms, and more patients achieved clinically meaningful changes in depressive symptoms based on PHQ-9, versus OAD + PBO. PHQ-9 outcomes were consistent with those of clinician-rated MADRS.TRIAL REGISTRATION: ClinicalTrials.gov: NCT02417064, NCT02418585, NCT02493868.PMID:38557430 | DOI:10.1017/S1092852924000105 (Source: CNS Spectrums)
Source: CNS Spectrums - April 1, 2024 Category: Neurology Authors: Jennifer Kern Sliwa Ronaldo R Naranjo Ibrahim Turkoz Mary Pat Petrillo Patricia Cabrera Madhukar Trivedi Source Type: research
Effects of esketamine nasal spray on depressive symptom severity in adults with treatment-resistant depression and associations between the Montgomery- Åsberg Depression Rating Scale and the 9-item Patient Health Questionnaire
CONCLUSIONS: In adults with TRD, ESK + OAD significantly improved severity of depressive symptoms, and more patients achieved clinically meaningful changes in depressive symptoms based on PHQ-9, versus OAD + PBO. PHQ-9 outcomes were consistent with those of clinician-rated MADRS.TRIAL REGISTRATION: ClinicalTrials.gov: NCT02417064, NCT02418585, NCT02493868.PMID:38557430 | DOI:10.1017/S1092852924000105 (Source: CNS Spectrums)
Source: CNS Spectrums - April 1, 2024 Category: Neurology Authors: Jennifer Kern Sliwa Ronaldo R Naranjo Ibrahim Turkoz Mary Pat Petrillo Patricia Cabrera Madhukar Trivedi Source Type: research
Effects of esketamine nasal spray on depressive symptom severity in adults with treatment-resistant depression and associations between the Montgomery- Åsberg Depression Rating Scale and the 9-item Patient Health Questionnaire
CONCLUSIONS: In adults with TRD, ESK + OAD significantly improved severity of depressive symptoms, and more patients achieved clinically meaningful changes in depressive symptoms based on PHQ-9, versus OAD + PBO. PHQ-9 outcomes were consistent with those of clinician-rated MADRS.TRIAL REGISTRATION: ClinicalTrials.gov: NCT02417064, NCT02418585, NCT02493868.PMID:38557430 | DOI:10.1017/S1092852924000105 (Source: CNS Spectrums)
Source: CNS Spectrums - April 1, 2024 Category: Neurology Authors: Jennifer Kern Sliwa Ronaldo R Naranjo Ibrahim Turkoz Mary Pat Petrillo Patricia Cabrera Madhukar Trivedi Source Type: research
Effects of esketamine nasal spray on depressive symptom severity in adults with treatment-resistant depression and associations between the Montgomery- Åsberg Depression Rating Scale and the 9-item Patient Health Questionnaire
CONCLUSIONS: In adults with TRD, ESK + OAD significantly improved severity of depressive symptoms, and more patients achieved clinically meaningful changes in depressive symptoms based on PHQ-9, versus OAD + PBO. PHQ-9 outcomes were consistent with those of clinician-rated MADRS.TRIAL REGISTRATION: ClinicalTrials.gov: NCT02417064, NCT02418585, NCT02493868.PMID:38557430 | DOI:10.1017/S1092852924000105 (Source: CNS Spectrums)
Source: CNS Spectrums - April 1, 2024 Category: Neurology Authors: Jennifer Kern Sliwa Ronaldo R Naranjo Ibrahim Turkoz Mary Pat Petrillo Patricia Cabrera Madhukar Trivedi Source Type: research
Effects of esketamine nasal spray on depressive symptom severity in adults with treatment-resistant depression and associations between the Montgomery- Åsberg Depression Rating Scale and the 9-item Patient Health Questionnaire
CONCLUSIONS: In adults with TRD, ESK + OAD significantly improved severity of depressive symptoms, and more patients achieved clinically meaningful changes in depressive symptoms based on PHQ-9, versus OAD + PBO. PHQ-9 outcomes were consistent with those of clinician-rated MADRS.TRIAL REGISTRATION: ClinicalTrials.gov: NCT02417064, NCT02418585, NCT02493868.PMID:38557430 | DOI:10.1017/S1092852924000105 (Source: CNS Spectrums)
Source: CNS Spectrums - April 1, 2024 Category: Neurology Authors: Jennifer Kern Sliwa Ronaldo R Naranjo Ibrahim Turkoz Mary Pat Petrillo Patricia Cabrera Madhukar Trivedi Source Type: research
Effects of esketamine nasal spray on depressive symptom severity in adults with treatment-resistant depression and associations between the Montgomery- Åsberg Depression Rating Scale and the 9-item Patient Health Questionnaire
CONCLUSIONS: In adults with TRD, ESK + OAD significantly improved severity of depressive symptoms, and more patients achieved clinically meaningful changes in depressive symptoms based on PHQ-9, versus OAD + PBO. PHQ-9 outcomes were consistent with those of clinician-rated MADRS.TRIAL REGISTRATION: ClinicalTrials.gov: NCT02417064, NCT02418585, NCT02493868.PMID:38557430 | DOI:10.1017/S1092852924000105 (Source: CNS Spectrums)
Source: CNS Spectrums - April 1, 2024 Category: Neurology Authors: Jennifer Kern Sliwa Ronaldo R Naranjo Ibrahim Turkoz Mary Pat Petrillo Patricia Cabrera Madhukar Trivedi Source Type: research
Effects of esketamine nasal spray on depressive symptom severity in adults with treatment-resistant depression and associations between the Montgomery- Åsberg Depression Rating Scale and the 9-item Patient Health Questionnaire
CNS Spectr. 2024 Apr 1:1-35. doi: 10.1017/S1092852924000105. Online ahead of print.NO ABSTRACTPMID:38557430 | DOI:10.1017/S1092852924000105 (Source: CNS Spectrums)
Source: CNS Spectrums - April 1, 2024 Category: Neurology Authors: Jennifer Kern Sliwa Ronaldo R Naranjo Ibrahim Turkoz Mary Pat Petrillo Patricia Cabrera Madhukar Trivedi Elizabeth Daloisio Source Type: research
Effects of esketamine nasal spray on depressive symptom severity in adults with treatment-resistant depression and associations between the Montgomery- Åsberg Depression Rating Scale and the 9-item Patient Health Questionnaire
CNS Spectr. 2024 Apr 1:1-35. doi: 10.1017/S1092852924000105. Online ahead of print.NO ABSTRACTPMID:38557430 | DOI:10.1017/S1092852924000105 (Source: CNS Spectrums)
Source: CNS Spectrums - April 1, 2024 Category: Neurology Authors: Jennifer Kern Sliwa Ronaldo R Naranjo Ibrahim Turkoz Mary Pat Petrillo Patricia Cabrera Madhukar Trivedi Elizabeth Daloisio Source Type: research
Effects of esketamine nasal spray on depressive symptom severity in adults with treatment-resistant depression and associations between the Montgomery- Åsberg Depression Rating Scale and the 9-item Patient Health Questionnaire
CNS Spectr. 2024 Apr 1:1-35. doi: 10.1017/S1092852924000105. Online ahead of print.NO ABSTRACTPMID:38557430 | DOI:10.1017/S1092852924000105 (Source: CNS Spectrums)
Source: CNS Spectrums - April 1, 2024 Category: Neurology Authors: Jennifer Kern Sliwa Ronaldo R Naranjo Ibrahim Turkoz Mary Pat Petrillo Patricia Cabrera Madhukar Trivedi Elizabeth Daloisio Source Type: research
Effects of esketamine nasal spray on depressive symptom severity in adults with treatment-resistant depression and associations between the Montgomery- Åsberg Depression Rating Scale and the 9-item Patient Health Questionnaire
CNS Spectr. 2024 Apr 1:1-35. doi: 10.1017/S1092852924000105. Online ahead of print.NO ABSTRACTPMID:38557430 | DOI:10.1017/S1092852924000105 (Source: CNS Spectrums)
Source: CNS Spectrums - April 1, 2024 Category: Neurology Authors: Jennifer Kern Sliwa Ronaldo R Naranjo Ibrahim Turkoz Mary Pat Petrillo Patricia Cabrera Madhukar Trivedi Elizabeth Daloisio Source Type: research
Effects of esketamine nasal spray on depressive symptom severity in adults with treatment-resistant depression and associations between the Montgomery- Åsberg Depression Rating Scale and the 9-item Patient Health Questionnaire
CNS Spectr. 2024 Apr 1:1-35. doi: 10.1017/S1092852924000105. Online ahead of print.NO ABSTRACTPMID:38557430 | DOI:10.1017/S1092852924000105 (Source: CNS Spectrums)
Source: CNS Spectrums - April 1, 2024 Category: Neurology Authors: Jennifer Kern Sliwa Ronaldo R Naranjo Ibrahim Turkoz Mary Pat Petrillo Patricia Cabrera Madhukar Trivedi Elizabeth Daloisio Source Type: research
Effects of esketamine nasal spray on depressive symptom severity in adults with treatment-resistant depression and associations between the Montgomery- Åsberg Depression Rating Scale and the 9-item Patient Health Questionnaire
CNS Spectr. 2024 Apr 1:1-35. doi: 10.1017/S1092852924000105. Online ahead of print.NO ABSTRACTPMID:38557430 | DOI:10.1017/S1092852924000105 (Source: CNS Spectrums)
Source: CNS Spectrums - April 1, 2024 Category: Neurology Authors: Jennifer Kern Sliwa Ronaldo R Naranjo Ibrahim Turkoz Mary Pat Petrillo Patricia Cabrera Madhukar Trivedi Elizabeth Daloisio Source Type: research
Adjunctive Cariprazine for Major Depressive Disorder: A Systematic Review and Meta-Analysis
CNS Spectr. 2024 Apr 1:1-37. doi: 10.1017/S1092852924000178. Online ahead of print.NO ABSTRACTPMID:38555956 | DOI:10.1017/S1092852924000178 (Source: CNS Spectrums)
Source: CNS Spectrums - March 31, 2024 Category: Neurology Authors: Hartej Gill David C J Chen-Li Sipan Haikazian Sam Seyedin Roger S McIntyre Rodrigo B Mansur Joshua D DiVincenzo Lee Phan Joshua D Rosenblat Source Type: research
Adjunctive Cariprazine for Major Depressive Disorder: A Systematic Review and Meta-Analysis
CNS Spectr. 2024 Apr 1:1-37. doi: 10.1017/S1092852924000178. Online ahead of print.NO ABSTRACTPMID:38555956 | DOI:10.1017/S1092852924000178 (Source: CNS Spectrums)
Source: CNS Spectrums - March 31, 2024 Category: Neurology Authors: Hartej Gill David C J Chen-Li Sipan Haikazian Sam Seyedin Roger S McIntyre Rodrigo B Mansur Joshua D DiVincenzo Lee Phan Joshua D Rosenblat Source Type: research
Trajectory and Magnitude of Response in Adults with Anxiety Disorders: A Bayesian Hierarchical Modeling Meta-Analysis of Selective Serotonin Reuptake Inhibitors, Serotonin Norepinephrine Reuptake Inhibitors and Benzodiazepines
CNS Spectr. 2024 Mar 25:1-22. doi: 10.1017/S1092852924000142. Online ahead of print.NO ABSTRACTPMID:38523533 | DOI:10.1017/S1092852924000142 (Source: CNS Spectrums)
Source: CNS Spectrums - March 25, 2024 Category: Neurology Authors: Eric M Mendez Jeffrey A Mills Vikram Suresh Julia N Stimpfl Jeffrey R Strawn Source Type: research
