Cardiovascular PathologyThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog. Subscribe to this data using MyMedWorm.Subscribe to this data using GoogleReader.Subscribe to this data using Bloglines.Subscribe to this data using MyYahoo.

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(Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - November 1, 2009 Category: Cardiology Tags: Society for Cardiovascular Pathology, Inc. Source Type: journals

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(Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - November 1, 2009 Category: Cardiology Tags: Society for Cardiovascular Pathology, Inc. Source Type: journals

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(Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - August 31, 2009 Category: Cardiology Source Type: journals

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(Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - August 31, 2009 Category: Cardiology Source Type: journals

ContentsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - June 30, 2009 Category: Cardiology Source Type: journals

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(Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - June 30, 2009 Category: Cardiology Source Type: journals

Table of ContentsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - April 28, 2009 Category: Cardiology Source Type: journals

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(Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - April 28, 2009 Category: Cardiology Source Type: journals

Asymptomatic inflammatory myofibroblastic tumor of the heart: immunohistochemical profile, differential diagnosis, and review of the literatureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The present case showed morphologic and immunohistochemical features characteristic of IMT. Immunohistochemistry was helpful for characterization and differential diagnosis. The immunoreactivity pattern (including calponin expression) was similar to that of extracardiac IMTs except for anaplastic lymphoma kinase 1 immunoreactivity, lacking in this benign intracardiac IMT but usually associated to favourable prognosis in extracardiac IMTs. (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - April 28, 2009 Category: Cardiology Authors: Angela Pucci, Andrea Valori, Maruska Muscio, Luca Garofalo, Francesca Ferroni, Pietro Angelo Abbruzzese Source Type: journals

Hypothyroidism-induced myocardial damage and heart failure: an overlooked entityEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Asymptomatic hypothyroidism may cause severe reduction in cardiac function accompanied with elevated cardiac enzymes. To our knowledge, this is the first description of human myocardial biopsy revealing mucopolysaccharide accumulation attributed to hypothyroid state. (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - April 28, 2009 Category: Cardiology Authors: Mony Shuvy, Oshrat E. Tayer Shifman, Samir Nusair, Orit Pappo, Chaim Lotan Source Type: journals

Endometrial adenocarcinoma metastatic to the right ventricle: a case report and review of the literatureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Management of metastatic adenocarcinoma to the heart is not well established due to the rarity of this lesion. Previously reported cases vary in the therapeutic approach as well as the outcome. To this date the best outcome has been a survival of 6 years after treatment of the metastasis with radiotherapy and concurrent cisplatin and pegylated liposomal doxorubicin. (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - April 28, 2009 Category: Cardiology Authors: Mario Castillo-Sang, Kristine Slam, Barbu Gociman, Samuel J. Durham, Robert Booth Source Type: journals

Expression of tenascin-c and CD44 receptors in cardiac myxomasEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Background: Myxomas are the most frequent primary cardiac neoplasms. They have an abundant extracellular matrix rich in proteoglycans. Interactions between cells and matrix are very important in the development of tumors, but data about myxomas in this setting are scarce because of the rarity of such neoplasms. The expression of tenascin-c and hyaluran receptors in cardiac myxoma has never been investigated. Moreover, it is now well recognized that cells of cardiac myxoma differentiate along endothelial lines.Methods: We have analyzed left atrial myxomas from 13 consecutive patients (six male and seven female, su...
Source: Cardiovascular Pathology - April 28, 2009 Category: Cardiology Authors: Giuseppe Donato, Francesco Conforti, Valeria Zuccalà, Emilio Russo, Lorenza Maltese, Ida Perrotta, Andrea Amorosi Source Type: journals

Up-regulation of a hydrogen peroxide–responsive pre-mRNA binding protein in atherosclerosis and intimal hyperplasiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The H2O2 responsive pre-mRNA binding protein hnRNP-C is up-regulated in atherosclerosis and in preatherosclerotic intimal hyperplasia in humans, supporting the hypothesis that H2O2 is a regulator of vascular cell proliferation in these conditions. These data also suggest that hnRNP-C may be useful as a marker of vascular cell activation. (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - April 28, 2009 Category: Cardiology Authors: Mikhail P. Panchenko, Nilsa Silva, James R. Stone Source Type: journals

Cardiac oxidative stress and remodeling following infarction: role of NADPH oxidaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Our findings indicate that during NADPH oxidase deficiency, superoxide production can be compensated by other sources, which leads to cardiac oxidative stress and its related molecular/cellular events in the infarcted heart. (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - April 28, 2009 Category: Cardiology Authors: Wenyuan Zhao, Dawn Zhao, Ran Yan, Yao Sun Source Type: journals

Gender-specific differences in aortic sinus curvature during aging: an anatomical and computational studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: We established significant gender-specific disparities in the aortic root during aging: while aortic sinus curvature was high in females throughout their lives, it experienced a more than fourfold increase in the lifetime of males, matching values in females only by age 65. Our mechanical analyses confirmed the overall potential protective role of higher sinus wall curvature with respect to type A aortic dissection, and geometry alone could not account for the known gender difference in aortic dissection prevalence. (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - April 28, 2009 Category: Cardiology Authors: Carsten J. Beller, Tilman Maurer, Michel R. Labrosse, Thierry Mesana, Matthias Karck, John P. Veinot Source Type: journals

Beneficial effects of fenofibrate on plaque thrombogenicity and plaque stability in atherosclerotic rabbitsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Background: Fibrates are peroxisome proliferator-activated receptor α (PPARα) agonists which modulate many aspects of lipoprotein metabolism and inflammation. They have been recently demonstrated to inhibit in vitro expression of tissue factor (TF), the main initiator of blood coagulation, which probably plays a pivotal role in thrombotic complications after plaque rupture. We investigated whether a 4-week fenofibrate treatment might affect the TF expression and cellular modifications in angioplasty-induced rabbit plaque rupture.Methods: After plaque rupture by balloon angioplasty in atheromatous rabbits, anima...
Source: Cardiovascular Pathology - April 28, 2009 Category: Cardiology Authors: Emmanuelle Jeanpierre, Thierry Le Tourneau, Christophe Zawadzki, Eric Van Belle, Frederic Mouquet, Sophie Susen, Michael D. Ezekowitz, Bart Staels, Brigitte Jude, Delphine Corseaux Source Type: journals

Pathology of the thoracic aorta: a morphologic review of 338 surgical specimens over a 7-year periodEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: A total of 338 surgical specimens of the thoracic aorta were studied morphologically. These were obtained from patients (238 males, 100 females) operated on for aortic aneurysm or dissection at the Careggi Hospital, Florence, Italy, between January 1999 and June 2005. Medial degeneration was diagnosed in 299 cases (138 aneurysms, 161 dissections), atherosclerosis with extensive medial destruction was seen in 32 cases (26 aneurysms, 6 dissections), and giant cell arteritis (GCA) was found in 7 cases (all aneurysms). These data show that medial degeneration was a common nonspecific histologic diagnosis in aortic re...
Source: Cardiovascular Pathology - April 28, 2009 Category: Cardiology Authors: Gabriella Nesi, Chiara Anichini, Silvia Tozzini, Vieri Boddi, Giancarlo Calamai, Franca Gori Source Type: journals

A practical method to rapidly dissolve metallic stentsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe a practical, rapid and cost-effective method to dissolve most metallic stents leaving the vascular and luminal tissues intact. This practical method may replace the laborious and expensive plastic embedding methods currently utilized. (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - April 28, 2009 Category: Cardiology Authors: Scott H. Bradshaw, Lloyd Kennedy, David F. Dexter, John P. Veinot Source Type: journals

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(Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - March 1, 2009 Category: Cardiology Source Type: journals

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(Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - March 1, 2009 Category: Cardiology Source Type: journals

Primary bi-atrial Burkitt lymphoma with severe inflow impairment in an immunocompetent patientEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report herein a case of sporadic primary cardiac bi-atrial Burkitt lymphoma (BL) occurred in a 67-year-old white immunocompetent patient and presenting with signs and symptoms of severe bilateral atrioventricular inflow impairment. Extranodal BL involving the heart is rare and seldom recognized clinically. Delayed discovery contributes to significant mortality. In the case presented extended surgical excision and intensive combination chemotherapy regiments resulted in complete remission at 1 year. (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - March 1, 2009 Category: Cardiology Authors: Francesco Santini, Francesco Innocente, Eliana Gilioli, Andrea Rossi, Antonella Ferrara, Matteo Brunelli, Giuseppe Faggian, Alessandro Mazzucco Tags: Case Reports Source Type: journals

Pericardial patch repair of the left atrioventricular valve in atrioventricular septal defect: long-term changes in the patchEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: A 31-year-old woman with partial atrioventricular septal defect underwent left atrioventricular valve (LAVV) replacement. Her initial repair was at 8 years of age. At 23 years of age, she underwent reoperation due to a combination of severe left ventricular outlet obstruction and moderate LAVV regurgitation. At that reoperation, she had a Dacron patch enlargement of the infundibular septum and repair of her LAVV with a xenograft (bovine) pericardial patch sutured into the superior bridging leaflet. LAVV replacement was required 8 years later because of valve insufficiency. There was a perforation in the patch wit...
Source: Cardiovascular Pathology - March 1, 2009 Category: Cardiology Authors: Adriana Luk, Eric Ahn, Gursharan S. Soor, William G. Williams, Melitta Mezody, Jagdish Butany Tags: Case Reports Source Type: journals

Isolated pericardial and intracardiac hydatidosis: presentation as congestive cardiac failure and fatal pulmonary embolismEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a case of massive pericardial hydatidosis in a female patient who presented with features of congestive cardiac failure. Cysts in the endocardium of right side of the heart resulted in fatal pulmonary embolism. (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - March 1, 2009 Category: Cardiology Authors: Ashish Katewa, Pradeep Vaideeswar, Jayant V. Khandekar, Sayed Sajid, Rahul M. Jawale, Nandkishore B. Agrawal, Pragati A. Sathe Tags: Case Reports Source Type: journals

Primary cardiac undifferentiated sarcoma of the right atrium presenting with cardiac tamponadeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report illustrates the serial imaging of a primary cardiac undifferentiated sarcoma of the right atrium using echocardiography, chest X-ray, and computed tomography. Transthoracic echocardiography on presentation showed an extensive mass of the right atrial free wall with an impending cardiac tamponade. Symptoms were controlled with pericardiocentesis, pericardial window, and radiotherapy but recurred 8 months later with pleural effusion and tumor spread to the great arteries. Primary cardiac sarcoma (PSC) is a rare and aggressive malignancy that is usually diagnosed late due to its nonspecific symptoms. Cytology and ...
Source: Cardiovascular Pathology - March 1, 2009 Category: Cardiology Authors: Poi Keong Kong, Stasinos Theodorou, Elisabeth Beran, Hardial Singh, Wadih Dimitri Tags: Case Reports Source Type: journals

Folic acid and methionine in the prevention of teratogen-induced congenital defects in miceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Our results suggest that folic acid and methionine periconceptional supplementations may influence the incidence of congenital defects and may probably induce negative selection of embryos presenting developmental anomalies. (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - March 1, 2009 Category: Cardiology Authors: Daria Cipollone, Rita Carsetti, Angela Tagliani, Maria Manuela Rosado, Paola Borgiani, Giuseppe Novelli, Giulia D'Amati, Lorenzo Fumagalli, Bruno Marino, Rita Businaro Tags: Original Articles Source Type: journals

Primary cardiac lymphoma: molecular cytogenetic characterization of a rare entityEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: In this single case, comparative genomic hybridization analysis using both bacterial artificial chromosome and oligonucleotide arrays correlated well with cytogenetic findings and allows for the cataloguing of more subtle genomic events. (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - March 1, 2009 Category: Cardiology Authors: Andrew J. Schell, Yuhui Xu, Tara Baetz, Karen Harrison, Glorianne Ropchan, David LeBrun, Harriet Feilotter Tags: Original Articles Source Type: journals

Local mechanical and structural properties of healthy and diseased human ascending aorta tissueEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Local variations in tissue thickness and mechanical properties were evident in all samples analyzed and may be linked to the type of aortic valve present. (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - March 1, 2009 Category: Cardiology Authors: Nusrat Choudhury, Olivier Bouchot, Leonie Rouleau, Dominique Tremblay, Raymond Cartier, Jagdish Butany, Rosaire Mongrain, Richard L. Leask Tags: Original Articles Source Type: journals

Role of carbonic anhydrase II in ectopic calcificationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Introduction: Osteopontin (OPN) is a potent inhibitor of ectopic calcification. Previous studies suggested that, in addition to blocking apatite crystal growth, OPN promoted regression of ectopic calcification by inducing the expression of acid-generating carbonic anhydrase II (CAR2) in monocyte-derived cells.Methods: To test this hypothesis, OPN and CAR2 expression and calcification of subcutaneously implanted glutaraldehyde-fixed bovine pericardium (GFBP) were studied in CAR2 mutant mice.Results: Consistent with previous studies in Black Swiss mice, GFBP calcified to a greater extent in OPN-deficient mice compa...
Source: Cardiovascular Pathology - March 1, 2009 Category: Cardiology Authors: Rupak M. Rajachar, Elyse Tung, Anh Q. Truong, Amy Look, Cecilia M. Giachelli Tags: Original Articles Source Type: journals

Identification of tissue factor in experimental aortic valve sclerosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Experimental AVS lesions that are present on the aortic side of leaflets display numerous characteristics of vascular atherosclerosis, including TF expression. Identification of TF associated with other components of the atherosclerotic process in AVS lesions strengthens the link between atherosclerosis and AVS. (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - March 1, 2009 Category: Cardiology Authors: Sylvestre Marechaux, Delphine Corseaux, Andre Vincentelli, Marjorie Richardson, Alexandre Ung, Sophie Susen, Christophe Zawadzki, Jean-Paul Beregi, Michael D. Ezekowitz, Brigitte Jude, Thierry Le Tourneau Tags: Original Articles Source Type: journals

Endomyocardial fibrosis as a cause of Budd-Chiari syndrome and fatal pulmonary embolism.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 24-year-old-man had right-sided heart failure of 3 months' duration. A Doppler echocardiogram revealed atrium and right ventricular enlargement, obliteration of the right ventricular apex, and a mass with an echolucent center measuring 20x21 mm in the right ventricular outlet. He died of pulmonary embolism. At autopsy, a huge organized thrombus obliterating the right ventricular apex passing through the tricuspid valve to the right atrium and then extending to the inferior vena cava up to the suprahepatic veins was seen. Histologically, an intense fibrotic thickening of the endomyocardium extending into the myocardiu...
Source: Cardiovascular Pathology - February 19, 2009 Category: Cardiology Authors: Bestetti RB, Silva CM, Ardito SQ, Theodoropoulos TA, Cury PM, Corbucci HA Tags: Cardiovasc Pathol Source Type: journals

In vivo characterization of cytokine profiles and viral load during murine cytomegalovirus-induced acute myocarditis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: MCMV-induced myocarditis in BALB/c mice is characterized by in vivo production of proinflammatory cytokines in a pattern correlating with MCMV viral load. The infection pattern and inflammatory response is highly localized, sporadic, and involves endocardium, epicardium, as well as the myocardium, with greatest amounts of virus detected in areas of pathologic calcification. PMID: 19217318 [PubMed - as supplied by publisher] (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - February 12, 2009 Category: Cardiology Authors: Ritter JT, Tang-Feldman YJ, Lochhead GR, Estrada M, Lochhead S, Yu C, Ashton-Sager A, Tuteja D, Leutenegger C, Pomeroy C Tags: Cardiovasc Pathol Source Type: journals

Relationship between circulating levels of monocyte chemoattractant protein-1 and systolic dysfunction in patients with hypertrophic cardiomyopathyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Background: Progression of hypertrophic cardiomyopathy (HCM) to left ventricular dilatation and systolic dysfunction sometimes occurs. However, the mechanism of the transition from hypertrophy to dysfunction has not been elucidated. It has been reported that circulating levels of monocyte chemoattractant protein-1 (MCP-1), which is a major factor promoting the accumulation of macrophages, are increased in patients with congestive heart failure. We measured circulating levels of MCP-1 in patients with HCM and examined whether MCP-1 was expressed in the myocardium of HCM patients. We also examined whether circulati...
Source: Cardiovascular Pathology - February 12, 2009 Category: Cardiology Authors: Jun Iwasaki, Kazufumi Nakamura, Hiromi Matsubara, Yoichi Nakamura, Nobuhiro Nishii, Kimikazu Banba, Masato Murakami, Keiko Ohta-Ogo, Hideo Kimura, Norihisa Toh, Satoshi Nagase, Takefumi Oka, Hiroshi Morita, Kengo Fukushima Kusano, Tohru Ohe Tags: Original Articles Source Type: journals

Giant congenital aortic aneurysm with cleft sternum in a neonate: pathological and surgical considerations for optimal management.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a rare case of a neonate with congenital giant aortic aneurysm associated to cleft sternum, who underwent surgical repair. The patient died on postoperative Day 5 from cardiac arrest. Autopsy revealed a circumferential subendocardial myocardial infarction and misdiagnosed coronary ostial anomalies. A critical analysis of this unfortunate case may help optimal surgical planning in similar patients in the future. PMID: 19216095 [PubMed - as supplied by publisher] (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - February 11, 2009 Category: Cardiology Authors: Padalino MA, Stellin G, Thiene G, Rubino M, Rizzo S, Milanesi O, Basso C Tags: Cardiovasc Pathol Source Type: journals

Creation, validation, and quantitative analysis of protein expression in vascular tissue microarrays.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: This study validates the use of TMA technology to investigate the vascular wall utilizing staining intensity data. PMID: 19211265 [PubMed - as supplied by publisher] (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - February 10, 2009 Category: Cardiology Authors: Halushka MK, Cornish TC, Lu J, Selvin S, Selvin E Tags: Cardiovasc Pathol Source Type: journals

Relationship between circulating levels of monocyte chemoattractant protein-1 and systolic dysfunction in patients with hypertrophic cardiomyopathy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: These results show that MCP-1 is associated with, and might be involved in the pathogenesis of, left ventricular systolic dysfunction in patients with HCM. PMID: 19211266 [PubMed - as supplied by publisher] (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - February 10, 2009 Category: Cardiology Authors: Iwasaki J, Nakamura K, Matsubara H, Nakamura Y, Nishii N, Banba K, Murakami M, Ohta-Ogo K, Kimura H, Toh N, Nagase S, Oka T, Morita H, Kusano KF, Ohe T Tags: Cardiovasc Pathol Source Type: journals

Atrial fibrillation is associated with cardiac hypoxia.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: AF is closely associated with an atrial up-regulation of hypoxic and angiogenic markers. Whether this is cause, effect, or co-phenomenon of fibrosis remains to be investigated. It is conceivable that fibrosis might lead to an increased O(2) diffusion distance and thus induce ischemic signaling, which, in turn, leads to angiogenesis. PMID: 19211267 [PubMed - as supplied by publisher] (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - February 10, 2009 Category: Cardiology Authors: Gramley F, Lorenzen J, Jedamzik B, Gatter K, Koellensperger E, Munzel T, Pezzella F Tags: Cardiovasc Pathol Source Type: journals

A practical method to rapidly dissolve metallic stents.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe a practical, rapid and cost-effective method to dissolve most metallic stents leaving the vascular and luminal tissues intact. This practical method may replace the laborious and expensive plastic embedding methods currently utilized. PMID: 19211268 [PubMed - as supplied by publisher] (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - February 10, 2009 Category: Cardiology Authors: Bradshaw SH, Kennedy L, Dexter DF, Veinot JP Tags: Cardiovasc Pathol Source Type: journals

Massive acute infarction of the right ventricular wall without or only minimal infarction of the left ventricular wall after aortic valve replacement with or without simultaneous replacement of the ascending aorta.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Certain clinical and cardiac morphologic findings are presented in two men who developed massive right ventricular (RV) infarction with only minimal or no left ventricular infarction early after aortic valve replacement. The ostium of the right coronary artery was severely narrowed in one patient by the ring of the bioprosthesis, and in the other patient the right coronary artery was completely severed at the time of valve replacement without insertion of a coronary bypass conduit. Such massive infarction of the RV free wall has not been reported previously. PMID: 19211269 [PubMed - as supplied by publisher] (Sourc...
Source: Cardiovascular Pathology - February 10, 2009 Category: Cardiology Authors: Roberts WC, Patterson BA, Ko JM, Sager RA, Clark JA, Guileyardo JM Tags: Cardiovasc Pathol Source Type: journals

Biomechanical stress induces novel arterial intima-enriched genes: implications for vascular adaptation to stress.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: These findings suggest a novel role for several human AIE genes in the VSMC response to arterialization and extended cyclic strain. SUMMARY: Biomechanical stress has long been implicated in vascular pathologies. We report the novel finding of a group of genes, previously studied in stratified epithelium, that were regulated by prolonged cyclic stress in vascular smooth muscle cells. This may have important implications to vascular disease. PMID: 19211270 [PubMed - as supplied by publisher] (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - February 10, 2009 Category: Cardiology Authors: Pyle AL, Li B, Maupin AB, Guzman RJ, Crimmins DL, Olson S, Atkinson JB, Young PP Tags: Cardiovasc Pathol Source Type: journals

Atrial expression of endothelial nitric oxide synthase in patients with and without atrial fibrillation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: AF does not independently effect atrial eNOS expression in humans. Due to the nonuniform regulation of endocardial eNOS expression, it appears unlikely that down-regulation of eNOS is a final common pathway for the development of prothrombotic endocardial remodeling, since classical risk factors for thromboembolic events do not reduce endocardial eNOS protein. PMID: 19211271 [PubMed - as supplied by publisher] (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - February 10, 2009 Category: Cardiology Authors: Bukowska A, Röcken C, Erxleben M, Röhl FW, Hammwöhner M, Huth C, Ebert MP, Lendeckel U, Goette A Tags: Cardiovasc Pathol Source Type: journals

Metastatic malignant melanoma manifesting as an intracardiac mass.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Melanoma is known to have an unpredictable and prolonged course. Neoplastic involvement of the heart should be considered in patients with cardiac symptoms when a documented malignancy exists, no matter how remote. PMID: 19211272 [PubMed - as supplied by publisher] (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - February 10, 2009 Category: Cardiology Authors: Wood A, Markovic SN, Best PJ, Erickson LA Tags: Cardiovasc Pathol Source Type: journals

Large animal models for diastolic dysfunction and diastolic heart failure-a review of the literature.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Diastolic heart failure (DHF) or heart failure with preserved systolic left ventricular function is estimated to account for approximately 40% of heart failure cases. Medical treatment of patients with DHF is limited and mainly empirical. Device-based therapy has an increasing role in the treatment of systolic heart failure and may have a future role in the treatment of DHF patients. Diastolic dysfunction and DHF are associated with anatomical and physiological characteristics, which need to be modeled in large animals in order to allow evaluation of device-based therapies, prior to clinical studies. In this article, w...
Source: Cardiovascular Pathology - February 10, 2009 Category: Cardiology Authors: Dubi S, Arbel Y Tags: Cardiovasc Pathol Source Type: journals

Aspergillus endocarditis in a known case of allergic bronchopulmonary aspergillosis: an autopsy report.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Invasive aspergillosis is an emerging infection mainly affecting immunocompromised patients. Aspergillus endocarditis remains a rare infection and usually occurs following cardiac surgery for prosthetic valves. This is an uncommon case of a 60-year-old asthmatic male who developed allergic bronchopulmonary aspergillosis during the course of his illness, and while receiving low dose oral steroids, he subsequently developed right-sided Aspergillus mural and native valvular endocarditis with extensive invasive pulmonary aspergillosis. PMID: 19211274 [PubMed - as supplied by publisher] (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - February 10, 2009 Category: Cardiology Authors: Gupta K, Das A, Joshi K, Singh N, Aggarwal R, Prakash M Tags: Cardiovasc Pathol Source Type: journals

Coronary ischemia and percutaneous intervention.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The interventional treatment of ischemia is a complex issue grounded on an understanding of basic pathophysiology, but translated and implemented in practice by extensive clinical trial data representing patients with a spectrum of ischemia-causing clinical syndromes and anatomical variations of coronary artery disease (CAD). Percutaneous coronary intervention (PCI) has evolved to treat ischemia within this matrix of clinical and anatomical subsets using a wide array of techniques. Initial techniques using balloon angioplasty were promising, but demonstrated significant rates of restenosis due to negative arterial remo...
Source: Cardiovascular Pathology - February 4, 2009 Category: Cardiology Authors: Hudson PA, Kim MS, Carroll JD Tags: Cardiovasc Pathol Source Type: journals

The effects of NK4 on viral myocarditis miceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: NK4 may be a promising agent to inhibit tumor invasion and metastasis. To observe the effects of NK4 on the cardiovascular system with pathological injury and to discuss the mechanism, we established an experimental model of viral myocarditis (VCM) by coxsackievirus B3 infection in Balb/c mice on Day 0 and administered NK4 twice daily to the VCM and control mice from Day 20 to Day 45. We then evaluated the cardiac function by means of ultrasonic inspection. Hepatocyte growth factor, TNF (tumor necrosis factor)-α, and angiotensin II levels in the myocardial tissue were measured with enzyme-linked immunosorbent as...
Source: Cardiovascular Pathology - January 16, 2009 Category: Cardiology Authors: Difei Shen, Qizhu Tang, Zhengrong Huang, Ying Chen, Ran Xiong, Hui Wu, Ji Huang, Siting Feng, Ling Yan, Zhouyan Bian Tags: Original Articles Source Type: journals

The ubiquitin–proteasome system contributes to the inflammatory injury in ischemic diabetic myocardium: the role of glycemic controlEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Background: Because the ubiquitin–proteasome pathway (UPS) is required for activation of nuclear factor kappa beta (NFkB), a transcription factor that regulates inflammatory genes, we evaluated the UPS activity, NFkB activation, and tumor necrosis factor-alpha (TNF-alpha), a proinflammatory cytokine, in ischemic specimens of diabetic myocardium and relate them to the glycemic control (HbA1c), oxidative stress (nitrotyrosine, a modified amino acid produced by reactive O2), and cardiac outcome (echocardiographic parameters). Moreover, the role of UPS, NFkB, and TNF-alpha in the cardiac tissue injury of acute isch...
Source: Cardiovascular Pathology - January 15, 2009 Category: Cardiology Authors: Raffaele Marfella, Clara Di Filippo, Michele Portoghese, Mario Siniscalchi, Simone Martis, Franca Ferraraccio, Salvatore Guastafierro, Gianfranco Nicoletti, Michelangela Barbieri, Antonino Coppola, Francesco Rossi, Giuseppe Paolisso, Michele D'Amico Tags: Original Articles Source Type: journals

Acute aortic dissection complicated by fistula from aorta to right ventricle through ventricular septumEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: A case report of aortic dissection (AoD) complicated by a shunt to the right ventricle is presented. Complications, treatment options, and survival of patients with Type A and Type B AoD are reviewed. (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - January 15, 2009 Category: Cardiology Authors: Dan Marek, Petr Němec, Kateřina Maderová, Miroslav Heřman, Marek Gwozdzievicz, Martin Troubil, Patrik Flodr, Jan Lukl Tags: Original Articles Source Type: journals

Lipomatous hypertrophy vs. cardiac hibernoma. What criteria differentiate them?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report an unusual case of adipocitary heart mass that did not fully satisfy the so-far valid criteria for lipomatous hypertrophy of interatrial septum (LHAS) and deviated from the features previous works attributed to LHAS to such a significant extent as to strongly point to the alternative diagnosis of cardiac hibernoma, which would be consistent with data available in the literature. (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - January 15, 2009 Category: Cardiology Authors: Vincenzo Arena, Luca Valerio, Arnaldo Capelli Tags: Correspondence Source Type: journals

Chlamydial lipopolysaccharide (cLPS) is present in atherosclerotic and aneurysmal arterial wall-cLPS levels depend on disease manifestation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: cLPS is present in arterial disease, and the potential role of C. pneumoniae in the pathogenesis of both peripheral atherosclerosis disease and AAA should not be forgotten. cLPS has a positive correlation with serum inflammatory markers, but this is no proof of a causal association. PMID: 19150246 [PubMed - as supplied by publisher] (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - January 14, 2009 Category: Cardiology Authors: Vikatmaa P, Lajunen T, Ikonen TS, Pussinen PJ, Lepäntalo M, Leinonen M, Saikku P Tags: Cardiovasc Pathol Source Type: journals

The effects of NK4 on viral myocarditis mice.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
NK4 may be a promising agent to inhibit tumor invasion and metastasis. To observe the effects of NK4 on the cardiovascular system with pathological injury and to discuss the mechanism, we established an experimental model of viral myocarditis (VCM) by coxsackievirus B3 infection in Balb/c mice on Day 0 and administered NK4 twice daily to the VCM and control mice from Day 20 to Day 45. We then evaluated the cardiac function by means of ultrasonic inspection. Hepatocyte growth factor, TNF (tumor necrosis factor)-alpha, and angiotensin II levels in the myocardial tissue were measured with enzyme-linked immunosorbent assay...
Source: Cardiovascular Pathology - January 14, 2009 Category: Cardiology Authors: Shen D, Tang Q, Huang Z, Chen Y, Xiong R, Wu H, Huang J, Feng S, Yan L, Bian Z Tags: Cardiovasc Pathol Source Type: journals