A case of Brucella aortitis associated with development of thoracic aortic aneurysm and aorto-bronchial fistula
The purpose of this case report is to document the occurrence of granulomatous aortitis complicated by formation of a saccular aneurysm and aorto-bronchial fistula due to Brucella infection. (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - November 7, 2018 Category: Cardiology Authors: Sarah J. Wu, Jacob C. Huddin, Audrey Wanger, Anthony L. Estrera, L. Maximilian Buja Tags: Case Report Source Type: research

Editorial Board
(Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - November 1, 2018 Category: Cardiology Source Type: research

Table of Contents
(Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - November 1, 2018 Category: Cardiology Source Type: research

Endomyocardial fibrosis and myocardial infarction leading to diastolic and systolic dysfunction requiring transplantation
We report the case of a 25- year old man of African origin who presented with end-stage heart failure due to both diastolic and systolic dysfunction and extensive endocavitary thrombosis as proven by echocardiography and cardiac magnetic resonance. EMF diagnosis was confirmed by endomyocardial biopsy and the patient had eventually cardiac transplantation. (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - October 30, 2018 Category: Cardiology Authors: Monica De Gaspari, Giuseppe Toscano, Lorenzo Bagozzi, Marco Metra, Carlo Lombardi, Stefania Rizzo, Annalisa Angelini, Martina Perazzolo Marra, Gino Gerosa, Cristina Basso Tags: Case Report Source Type: research

A cardiac mass beyond symptomatic palpitations
Case Report. (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - October 29, 2018 Category: Cardiology Authors: Gustavo S á Mendes, João Abecasis, Rosa Gouveia, Mariana Castro, Salomé Carvalho, Sância Ramos, Miguel Abecasis Tags: Case Report Source Type: research

CO2-related vasoconstriction superimposed on ischemic medullary brain autonomic nuclei may contribute to sudden death
In 2015, a multi-national randomized controlled phase IV clinical trial of adaptive servo-ventilation for the management of heart failure with central sleep apnea was halted in progress because more patients in the study group were dying than in the control group. One year later, another large clinical trial reported results on the effectiveness of continuous positive airway pressure (CPAP) in preventing sudden death and other cardiovascular events such as heart attack and stroke in patients with pre-existing vascular disease as well as obstructive sleep apnea. (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - October 26, 2018 Category: Cardiology Authors: J. Howard Jaster, Josef Zamecnik, Aldo Bruno Giann ì, Giulia Ottaviani Source Type: research

Morphology and mechanisms of a novel absorbable polymeric conduit in the pulmonary circulation of sheep
We report experimental in vivo experience with an entirely synthetic absorbable graft, designed to be replaced by tissue in-vivo by host cells, in a process termed Endogenous Tissue Restoration (ETR), and to grow commensurate with somatic growth. (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - October 25, 2018 Category: Cardiology Authors: Marieke Brugmans, Aur élie Serrero, Martijn Cox, Oleg Svanidze, Frederick J. Schoen Tags: Orignal Article Source Type: research

Vascular malformation in a bicuspid aortic valve
We report here a case of capillary vascular malformation developed in a bicuspid aortic valve incidentally detected during valve replacement in a 67-year-old male patient. The International Society for the Study of Vascular Anomalies (ISSVA) classification was used to classify this vascular lesion instead of using the term hemangioma. The differential diagnosis and the literature are reviewed. (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - October 24, 2018 Category: Cardiology Authors: Paul Cotier, Patrick Bruneval, Kisaki Amemiya Tags: Case Report Source Type: research

Expression of Tenascin C in Cardiovascular Lesions of Kawasaki Disease
To examine tenascin C (TN-C) expression in coronary artery lesions (CALs) and myocardial lesions (MLs) in Kawasaki disease (KD). (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - October 23, 2018 Category: Cardiology Authors: Yuki Yokouchi, Toshiaki Oharaseki, Yasunori Enomoto, Wakana Sato, Kyoko Imanaka-Yoshida, Kei Takahashi Tags: Original Article Source Type: research

Renal cystic disease in the Fbn1C1039G/+ Marfan mouse is associated with enhanced aortic aneurysm formation
Marfan syndrome (MFS) is a connective tissue disorder caused by mutations in the fibrillin-1 gene (FBN1), resulting in aortic aneurysm formation and dissections. Interestingly, variable aortopathy is observed, even within MFS families with the same mutation. Thus additional risk factors determine disease severity. Here, we describe a case of a 2-month old Fbn1C1039G/+ MFS mouse with extreme aortic dilatation and increased vascular inflammation, when compared to MFS siblings, which coincided with unilateral renal cystic disease. (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - October 16, 2018 Category: Cardiology Authors: Stijntje Hibender, Shaynah Wanga, Ingeborg van der Made, Mariska Vos, Barbara JM Mulder, Ron Balm, Carlie JM de Vries, Vivian de Waard Tags: Original Article Source Type: research

Pathological correlates of brain arterial calcifications
In this study, we examined if intracranial arterial calcifications were associated with cholesterol-mediated intracranial large artery atherosclerosis (ILAA) within the arteries of the Circle of Willis in an autopsy based sample. (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - October 12, 2018 Category: Cardiology Authors: Steven D. Shapiro, James Goldman, Susan Morgello, Lawrence Honig, Mitchell S.V. Elkind, Randolph S. Marshall, Jay P Mohr, Jose Gutierrez Tags: Original Article Source Type: research

Coronary artery myointimal dysplasia in patients with pheochromocytoma —possible causal relationship: pathophysiology and clinical implication with reference to Takotsubo cardiomyopathy and spontaneous coronary dissection
Myocardial damage in catecholamine cardiomyopathy, characterized by patchy myocyte necrosis commonly with contraction band appearances, interstitial fibrosis, and varying degrees of inflammatory infiltrates, has been well documented. However, coronary vascular pathology has not been recognized. Autopsy of a 43-year-old housewife who died of acute apical anteroseptal myocardial infarction revealed the incidental finding of a left adrenal pheochromocytoma. The epicardial and intramyocardial median- and small-sized coronary arteries exhibited myointimal dysplasia in the form of fibroblastic proliferation in the intima and med...
Source: Cardiovascular Pathology - October 11, 2018 Category: Cardiology Authors: Louis Tsun Cheung Chow, Maria Bernadette Che Ying Chow Tags: Original Article Source Type: research

Coronary artery Myointimal dysplasia in patients with Pheochromocytoma – possible causal relationship: pathophysiology and clinical implication with reference to Takotsubo cardiomyopathy and spontaneous coronary dissection
Myocardial damage in catecholamine cardiomyopathy, characterized by patchy myocyte necrosis commonly with contraction band appearances, interstitial fibrosis and varying degrees of inflammatory infiltrates has been well documented. However, coronary vascular pathology has not been recognized. Autopsy of a 43-year-old housewife, died of acute apical anteroseptal myocardial infarction, revealed the incidental finding of a left adrenal pheochromocytoma. The epicardial and intramyocardial median and small size coronary arteries exhibited myointimal dysplasia in the form of fibroblastic proliferation in the intima and media, re...
Source: Cardiovascular Pathology - October 11, 2018 Category: Cardiology Authors: Louis Tsun Cheung Chow, Maria Bernadette Che Ying Chow Tags: Original Article Source Type: research

A case of biopsy-proven eosinophilic myocarditis related to tetanus toxoid immunization
We report the first case of biopsy-proven eosinophilic myocarditis related to tetanus toxoid immunization, with unique histopathologic findings, characterized by perivascular eosinophilic infiltrates with myocyte necrosis and abundant interstitial lymphocytic infiltrates with myocyte necrosis, separately. A systemic high-dose corticosteroid treatment had a dramatic beneficial effect on hemodynamic instability, resulted in complete recovery. (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - October 9, 2018 Category: Cardiology Authors: Hiroyuki Yamamoto, Toru Hashimoto, Ohta-Ogo Keiko, Ishibashi-Ueda Hatsue, Kyoko Imanaka-Yoshida, Michiaki Hiroe, Tomoki Yokochi Tags: Case Report Source Type: research

Infrasound induces coronary perivascular fibrosis in rats
Chronic exposure to industrial noise is known to affect biological systems, namely by inducing fibrosis in the absence of inflammatory cells. In rat hearts exposed to this environmental hazard we have previously found myocardial and perivascular fibrosis. The acoustic spectrum of industrial environments is particularly rich in high intensity infrasound ( (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - October 9, 2018 Category: Cardiology Authors: Ana Lousinha, Maria Jo ão R. Oliveira, Gonçalo Borrecho, José Brito, Pedro Oliveira, António Oliveira de Carvalho, Diamantino Freitas, Artur P. Águas, Eduardo Antunes Tags: Original Article Source Type: research