Cardiovascular and Hematological Agents in Medicinal Chemistry 
This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.
This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Mavacamten: A Review of a Novel Therapeutic Approach for Hypertrophic Cardiomyopathy
Cardiovasc Hematol Agents Med Chem. 2024 Apr 5. doi: 10.2174/0118715257283752240325082733. Online ahead of print.ABSTRACTHypertrophic Cardiomyopathy (HCM) is a heart disease that can cause left ventricular hypertrophy, arrhythmias, heart failure, and sudden cardiac death. Currently, pharmacological treatment is limited and ineffective. Mavacamten (CamzyosTM) is a cardiac myosin inhibitor developed as a therapeutic option to reduce myocardial contractility and restoration of myocardial function. The Food and Drug Administration (FDA) approved the use of Mavacamten in 2022 for HCM symptoms. Clinical studies have proven that ...
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - April 8, 2024 Category: Cardiology Authors: Ayesha Abdul Qadir Memon Areeba Shamim Sanoober Mirza Muhammad Osama Iyad Naeem Muhammad Calvin R Wei Source Type: research
Redox-signalling and Redox Biomarkers in Cardiovascular Health and Disease
Cardiovasc Hematol Agents Med Chem. 2024 Feb 15. doi: 10.2174/0118715257282030240130095754. Online ahead of print.ABSTRACTOverproduction of reactive nitrogen and oxygen species (RNS and ROS) has been linked to the pathogenesis of diabetes, hypertension, hyperlipidemia, stroke, angina, and other cardiovascular diseases. These species are produced in part by the mitochondrial respiratory chain, NADPH oxidase, and xanthine oxidase. RNS and ROS both contribute to oxidative stress, which is necessary for the development of cardiovascular disorders. In addition to ROS species like hydroxyl ion, hydrogen peroxide, and superoxide ...
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - March 29, 2024 Category: Cardiology Authors: Yasmin Sultana Damanpreet Kaur Lang Thomson Santosh Alex Rakhi Khabiya Akanksha Dwivedi Saikat Sen Raja Chakraborty Source Type: research
Effect of Syzygium cumini on Oxidative Stress Induced Cardiac Cellular Anomalies
CONCLUSION: Conclusively, Syzygium cumini possesses cardioprotective potential in H9C2 cardiomyocytes in dox-induced cardiotoxicity.PMID:38299280 | DOI:10.2174/0118715257273859231211112731 (Source: Cardiovascular and Hematological Agents in Medicinal Chemistry)
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - February 1, 2024 Category: Cardiology Authors: Renu Bhadana Vibha Rani Source Type: research
