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Uranium (U) Toxicity | ATSDR - CSEMEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Everyone is exposed to uranium in food, air, and water as part of the natural environment. Most exposures do not warrant monitoring or treatment. Populations most heavily exposed to uranium are those employed in mining and milling operations, or in uranium enrichment and processing activities. Natural and depleted uranium are primarily chemical toxicants, with radiation playing a minor role or no role at all. Outcomes that may occur with uranium over exposure based on both observed human effects and animal studies include non-malignant respiratory disease (fibrosis, emphysema) and nephrotoxicity. Nephrotoxicity should reve...
Source: Case Studies in Environmental Medicine | ATSDR - CSEM - May 1, 2009 Category: Environmental Health Source Type: organizations

Uranium (U) Toxicity | ATSDR - Environmental Medicine & Environmental Health Education - CSEMEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Everyone is exposed to uranium in food, air, and water as part of the natural environment. Most exposures do not warrant monitoring or treatment. Populations most heavily exposed to uranium are those employed in mining and milling operations, or in uranium enrichment and processing activities. Natural and depleted uranium are primarily chemical toxicants, with radiation playing a minor role or no role at all. Outcomes that may occur with uranium overexposure, based on both observed human effects and animal studies, include non-malignant respiratory disease (fibrosis, emphysema) and nephrotoxicity. Nephrotoxicity should rev...
Source: Case Studies in Environmental Medicine | ATSDR - CSEM - May 1, 2009 Category: Environmental Health Source Type: organizations

Chromium Toxicity | ATSDR - CSEMEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The toxicity of chromium compounds depends on the oxidation state of the metal. Occupational exposure to chromium(VI) compounds has been associated with increased incidence of lung cancer. Chromium(III) is an essential nutrient that can be toxic in large doses.
Source: Case Studies in Environmental Medicine | ATSDR - CSEM - December 18, 2008 Category: Environmental Health Source Type: organizations

Chromium Toxicity | ATSDR - Environmental Medicine & Environmental Health Education - CSEMEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The toxicity of chromium compounds depends on the oxidation state of the metal. Occupational exposure to chromium(VI) compounds has been associated with increased incidence of lung cancer. Chromium(III) is an essential nutrient that can be toxic in large doses.
Source: Case Studies in Environmental Medicine | ATSDR - CSEM - December 18, 2008 Category: Environmental Health Source Type: organizations

Beryllium Toxicity | ATSDR - CSEMEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Beryllium produces health effects ranging from sensitization without evidence of disease to clinically apparent pulmonary disease. Chronic beryllium disease may be misdiagnosed as sarcoidosis. Immunologic tests can detect beryllium sensitization and help clinicians differentiate between chronic beryllium disease and other interstitial lung diseases.
Source: Case Studies in Environmental Medicine | ATSDR - CSEM - May 23, 2008 Category: Environmental Health Source Type: organizations

Tetrachloroethylene (PCE) Toxicity | ATSDR - CSEMEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Tetrachloroethylene is used mainly as a solvent for dry cleaning and metal degreasing. Like most chlorinated solvents, tetrachloroethylene can cause central nervous system depression. Chronic exposure to tetrachloroethylene may adversely affect the neurological system, liver, and kidneys. Tetrachloroethylene is reasonably anticipated to be a human carcinogen on the basis of limited evidence from studies in humans and sufficient evidence of carcinogenicity from studies in experimental animals.
Source: Case Studies in Environmental Medicine | ATSDR - CSEM - May 23, 2008 Category: Environmental Health Source Type: organizations

Beryllium Toxicity | ATSDR - Environmental Medicine & Environmental Health Education - CSEMEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Beryllium produces health effects ranging from sensitization without evidence of disease to clinically apparent pulmonary disease. Chronic beryllium disease may be misdiagnosed as sarcoidosis. Immunologic tests can detect beryllium sensitization and help clinicians differentiate between chronic beryllium disease and other interstitial lung diseases.
Source: Case Studies in Environmental Medicine | ATSDR - CSEM - May 23, 2008 Category: Environmental Health Source Type: organizations

Tetrachloroethylene (PCE) Toxicity | ATSDR - Environmental Medicine & Environmental Health Education - CSEMEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Tetrachloroethylene is used mainly as a solvent for dry cleaning and metal degreasing. Like most chlorinated solvents, tetrachloroethylene can cause central nervous system depression. Chronic exposure to tetrachloroethylene may adversely affect the neurological system, liver, and kidneys. Tetrachloroethylene is reasonably anticipated to be a human carcinogen on the basis of limited evidence from studies in humans and sufficient evidence of carcinogenicity from studies in experimental animals.
Source: Case Studies in Environmental Medicine | ATSDR - CSEM - May 23, 2008 Category: Environmental Health Source Type: organizations

Cadmium Toxicity | ATSDR - CSEMEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Prevention is the key to managing cadmium exposure. No effective treatment for cadmium toxicity exists. For the general public, the primary source of exposure to cadmium is dietary. Smoking tobacco adds an additional burden of cadmium. Nutritional deficiencies can increase the risk of cadmium toxicity. Chronic cadmium exposure primarily affects the kidneys and secondarily the bones. Acute inhalation of fumes containing cadmium affects the lungs.
Source: Case Studies in Environmental Medicine | ATSDR - CSEM - May 12, 2008 Category: Environmental Health Source Type: organizations

Taking an Exposure History | ATSDR - CSEMEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Because many environmental diseases either manifest as common medical problems or have nonspecific symptoms, an exposure history is vital for correct diagnosis. By taking a thorough exposure history, the primary care clinician can play an important role in detecting, treating, and preventing disease due to toxic exposure.
Source: Case Studies in Environmental Medicine | ATSDR - CSEM - May 12, 2008 Category: Environmental Health Source Type: organizations

Cadmium Toxicity | ATSDR - Environmental Medicine & Environmental Health Education - CSEMEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Prevention is the key to managing cadmium exposure. No effective treatment for cadmium toxicity exists. For the general public, the primary source of exposure to cadmium is dietary. Smoking tobacco adds an additional burden of cadmium. Nutritional deficiencies can increase the risk of cadmium toxicity. Chronic cadmium exposure primarily affects the kidneys and secondarily the bones. Acute inhalation of fumes containing cadmium affects the lungs.
Source: Case Studies in Environmental Medicine | ATSDR - CSEM - May 12, 2008 Category: Environmental Health Source Type: organizations

Taking an Exposure History | ATSDR - Environmental Medicine & Environmental Health Education - CSEMEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Because many environmental diseases either manifest as common medical problems or have nonspecific symptoms, an exposure history is vital for correct diagnosis. By taking a thorough exposure history, the primary care clinician can play an important role in detecting, treating, and preventing disease due to toxic exposure.
Source: Case Studies in Environmental Medicine | ATSDR - CSEM - May 12, 2008 Category: Environmental Health Source Type: organizations

Asbestos Toxicity | ATSDR - CSEMEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Although asbestos is no longer used in many products, it will remain a public health concern well into the 21st century. Intact asbestos sources in the home release few fibers and should be left undisturbed. Damaged or crumbling materials should be repaired or removed only by certified asbestos-removal professionals. Asbestos exposure is associated with parenchymal asbestosis, asbestos-related pleural abnormalities, mesothelioma, and lung cancer, and it may be associated with cancer at some extra thoracic sites.
Source: Case Studies in Environmental Medicine | ATSDR - CSEM - November 16, 2007 Category: Environmental Health Source Type: organizations

Asbestos Toxicity | ATSDR - Environmental Medicine & Environmental Health Education - CSEMEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Although asbestos is no longer used in many products, it will remain a public health concern well into the 21st century. Intact asbestos sources in the home release few fibers and should be left undisturbed. Damaged or crumbling materials should be repaired or removed only by certified asbestos-removal professionals. Asbestos exposure is associated with parenchymal asbestosis, asbestos-related pleural abnormalities, mesothelioma, and lung cancer, and it may be associated with cancer at some extra thoracic sites.
Source: Case Studies in Environmental Medicine | ATSDR - CSEM - November 16, 2007 Category: Environmental Health Source Type: organizations

Trichloroethylne (TCE) Toxicity | ATSDR - CSEMEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Trichloroethylene (TCE) is a common industrial solvent and contaminant of hazardous waste sites, groundwater, and drinking water. TCE is a CNS depressant and a suspected hepatotoxin in humans. TCE is reasonably anticipated to be a human carcinogen based on limited evidence of carcinogenicity from studies in humans and sufficient evidence of carcinogenicity from studies in experimental animals.
Source: Case Studies in Environmental Medicine | ATSDR - CSEM - November 8, 2007 Category: Environmental Health Source Type: organizations

Trichloroethylne (TCE) Toxicity | ATSDR - Environmental Medicine & Environmental Health Education - CSEMEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Trichloroethylene (TCE) is a common industrial solvent and contaminant of hazardous waste sites, groundwater, and drinking water. TCE is a CNS depressant and a suspected hepatotoxin in humans. TCE is reasonably anticipated to be a human carcinogen based on limited evidence of carcinogenicity from studies in humans and sufficient evidence of carcinogenicity from studies in experimental animals.
Source: Case Studies in Environmental Medicine | ATSDR - CSEM - November 8, 2007 Category: Environmental Health Source Type: organizations

Environmental Triggers of Asthma | ATSDR - CSEMEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Asthma is a chronic inflammatory disease of the airways. Over the past decade, the prevalence of asthma in children and adults has increased in the United States. Environmental exposures to allergens, air pollutants, and environmental tobacco smoke, and workplace exposures can cause and exacerbate asthma. Control of environmental exposures can significantly improve the quality of life of people with asthma.
Source: Case Studies in Environmental Medicine | ATSDR - CSEM - October 17, 2007 Category: Environmental Health Source Type: organizations

Environmental Triggers of Asthma | ATSDR - Environmental Medicine & Environmental Health Education - CSEMEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Asthma is a chronic inflammatory disease of the airways. Over the past decade, the prevalence of asthma in children and adults has increased in the United States. Environmental exposures to allergens, air pollutants, and environmental tobacco smoke, and workplace exposures can cause and exacerbate asthma. Control of environmental exposures can significantly improve the quality of life of people with asthma.
Source: Case Studies in Environmental Medicine | ATSDR - CSEM - October 17, 2007 Category: Environmental Health Source Type: organizations

Cholinesterase Inhibitors, Including Pesticides and Chemical Warfare Nerve Agents | ATSDR - CSEMEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Cholinesterase inhibitors are a class of compounds that includes chemical warfare nerve agents and certain insecticides. Fatalities occur mainly due to effects on respiration due depression of respiratory drive, paralysis of muscles of respiration, bronchoconstriction, and airway obstruction from profuse respiratory tract secretions. Treatment includes the use of atropine, 2-PAM, diazepam, and aggressive supportive care.
Source: Case Studies in Environmental Medicine | ATSDR - CSEM - October 16, 2007 Category: Environmental Health Source Type: organizations

Cholinesterase Inhibitors, Including Insecticides and Chemical Warfare Nerve Agents | ATSDR - CSEMEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Cholinesterase inhibitors are a class of compounds that includes chemical warfare nerve agents and certain insecticides. Fatalities occur mainly due to effects on respiration due depression of respiratory drive, paralysis of muscles of respiration, bronchoconstriction, and airway obstruction from profuse respiratory tract secretions. Treatment includes the use of atropine, 2-PAM, diazepam, and aggressive supportive care.
Source: Case Studies in Environmental Medicine | ATSDR - CSEM - October 16, 2007 Category: Environmental Health Source Type: organizations

Cholinesterase Inhibitors, Including Insecticides and Chemical Warfare Nerve Agents | ATSDR - Environmental Medicine & Environmental Health Education - CSEMEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Cholinesterase inhibitors are a class of compounds that includes chemical warfare nerve agents and certain insecticides. Fatalities occur mainly due to effects on respiration due depression of respiratory drive, paralysis of muscles of respiration, bronchoconstriction, and airway obstruction from profuse respiratory tract secretions. Treatment includes the use of atropine, 2-PAM, diazepam, and aggressive supportive care.
Source: Case Studies in Environmental Medicine | ATSDR - CSEM - October 16, 2007 Category: Environmental Health Source Type: organizations

Ethylene Glycol and Polyethylene Glycol Toxicity | ATSDR - CSEMEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Ethylene glycol ingestion first affects the central nervous system (CNS). After a characteristic latent period, signs of inebriation may be followed by serious illness and even death, caused by toxic metabolites. Propylene glycol, which is much less toxic than ethylene glycol, is metabolized to compounds that are normal constituents of the citric acid cycle. No health effects have been reported in persons chronically exposed to ethylene glycol or propylene glycol at levels found in the environment.
Source: Case Studies in Environmental Medicine | ATSDR - CSEM - October 7, 2007 Category: Environmental Health Source Type: organizations

Ethylene Glycol and Polyethylene Glycol Toxicity | ATSDR - Environmental Medicine & Environmental Health Education - CSEMEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Ethylene glycol ingestion first affects the central nervous system (CNS). After a characteristic latent period, signs of inebriation may be followed by serious illness and even death, caused by toxic metabolites. Propylene glycol, which is much less toxic than ethylene glycol, is metabolized to compounds that are normal constituents of the citric acid cycle. No health effects have been reported in persons chronically exposed to ethylene glycol or propylene glycol at levels found in the environment.
Source: Case Studies in Environmental Medicine | ATSDR - CSEM - October 7, 2007 Category: Environmental Health Source Type: organizations

Nitrate/Nitrite Toxicity | ATSDR - CSEMEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nitrate toxicity is a preventable cause of methemoglobinemia. Infants younger than 4 months of age are at particular risk of nitrate toxicity from contaminated well water. The widespread use of nitrate fertilizers increases the risk of well-water contamination in rural areas..
Source: Case Studies in Environmental Medicine | ATSDR - CSEM - September 24, 2007 Category: Environmental Health Source Type: organizations

Nitrate/Nitrite Toxicity | ATSDR - Environmental Medicine & Environmental Health Education - CSEMEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nitrate toxicity is a preventable cause of methemoglobinemia. Infants younger than 4 months of age are at particular risk of nitrate toxicity from contaminated well water. The widespread use of nitrate fertilizers increases the risk of well-water contamination in rural areas..
Source: Case Studies in Environmental Medicine | ATSDR - CSEM - September 24, 2007 Category: Environmental Health Source Type: organizations

Lead Toxicity | ATSDR - CSEMEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Children of all races and ethnic origins are at risk of lead toxicity throughout the U.S. Lead may cause irreversible neurological damage as well as renal disease, cardiovascular effects, and reproductive toxicity. Blood lead levels once considered safe are now considered hazardous, with no known threshold. Lead poisoning is a wholly preventable disease.
Source: Case Studies in Environmental Medicine | ATSDR - CSEM - August 20, 2007 Category: Environmental Health Source Type: organizations

Lead Toxicity | ATSDR - Environmental Medicine & Environmental Health Education - CSEMEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Children of all races and ethnic origins are at risk of lead toxicity throughout the U.S. Lead may cause irreversible neurological damage as well as renal disease, cardiovascular effects, and reproductive toxicity. Blood lead levels once considered safe are now considered hazardous, with no known threshold. Lead poisoning is a wholly preventable disease.
Source: Case Studies in Environmental Medicine | ATSDR - CSEM - August 20, 2007 Category: Environmental Health Source Type: organizations