BMP7-induced osteoblast differentiation requires hedgehog signaling and involves nuclear mechanisms of gene expression control
In conclusion, this study highlights the positive impact of epigenetic control on the expression of genes related to hedgehog signaling during the morphogenetic changes induced by BMP7 signaling in osteoblasts.PMID:38591759 | DOI:10.1002/cbin.12161 (Source: Cell Biology International)
Source: Cell Biology International - April 9, 2024 Category: Cytology Authors: Georgia da Silva Feltran Amanda Fantini de Andrade C élio Jr da C Fernandes Rodrigo A Foganholi da Silva Willian F Zambuzzi Source Type: research

Effects of syndecan-4 silencing on the extracellular matrix remodeling in anoikis-resistant endothelial cells
In conclusion, these data demonstrate that SDC4 plays an important role in ECM remodeling. In addition, our findings represent an important step toward understanding the mechanism by which SDC4 can reverse the transformed phenotype of anoikis-resistant endothelial cells.PMID:38591778 | DOI:10.1002/cbin.12158 (Source: Cell Biology International)
Source: Cell Biology International - April 9, 2024 Category: Cytology Authors: Jessica Oyie Sousa Onyeisi Helena Bonciani Nader Carla Cristina Lopes Source Type: research

BMP7-induced osteoblast differentiation requires hedgehog signaling and involves nuclear mechanisms of gene expression control
In conclusion, this study highlights the positive impact of epigenetic control on the expression of genes related to hedgehog signaling during the morphogenetic changes induced by BMP7 signaling in osteoblasts.PMID:38591759 | DOI:10.1002/cbin.12161 (Source: Cell Biology International)
Source: Cell Biology International - April 9, 2024 Category: Cytology Authors: Georgia da Silva Feltran Amanda Fantini de Andrade C élio Jr da C Fernandes Rodrigo A Foganholi da Silva Willian F Zambuzzi Source Type: research

Effects of syndecan-4 silencing on the extracellular matrix remodeling in anoikis-resistant endothelial cells
In conclusion, these data demonstrate that SDC4 plays an important role in ECM remodeling. In addition, our findings represent an important step toward understanding the mechanism by which SDC4 can reverse the transformed phenotype of anoikis-resistant endothelial cells.PMID:38591778 | DOI:10.1002/cbin.12158 (Source: Cell Biology International)
Source: Cell Biology International - April 9, 2024 Category: Cytology Authors: Jessica Oyie Sousa Onyeisi Helena Bonciani Nader Carla Cristina Lopes Source Type: research

BMP7-induced osteoblast differentiation requires hedgehog signaling and involves nuclear mechanisms of gene expression control
In conclusion, this study highlights the positive impact of epigenetic control on the expression of genes related to hedgehog signaling during the morphogenetic changes induced by BMP7 signaling in osteoblasts.PMID:38591759 | DOI:10.1002/cbin.12161 (Source: Cell Biology International)
Source: Cell Biology International - April 9, 2024 Category: Cytology Authors: Georgia da Silva Feltran Amanda Fantini de Andrade C élio Jr da C Fernandes Rodrigo A Foganholi da Silva Willian F Zambuzzi Source Type: research

Effects of syndecan-4 silencing on the extracellular matrix remodeling in anoikis-resistant endothelial cells
In conclusion, these data demonstrate that SDC4 plays an important role in ECM remodeling. In addition, our findings represent an important step toward understanding the mechanism by which SDC4 can reverse the transformed phenotype of anoikis-resistant endothelial cells.PMID:38591778 | DOI:10.1002/cbin.12158 (Source: Cell Biology International)
Source: Cell Biology International - April 9, 2024 Category: Cytology Authors: Jessica Oyie Sousa Onyeisi Helena Bonciani Nader Carla Cristina Lopes Source Type: research

BMP7-induced osteoblast differentiation requires hedgehog signaling and involves nuclear mechanisms of gene expression control
In conclusion, this study highlights the positive impact of epigenetic control on the expression of genes related to hedgehog signaling during the morphogenetic changes induced by BMP7 signaling in osteoblasts.PMID:38591759 | DOI:10.1002/cbin.12161 (Source: Cell Biology International)
Source: Cell Biology International - April 9, 2024 Category: Cytology Authors: Georgia da Silva Feltran Amanda Fantini de Andrade C élio Jr da C Fernandes Rodrigo A Foganholi da Silva Willian F Zambuzzi Source Type: research

Effects of syndecan-4 silencing on the extracellular matrix remodeling in anoikis-resistant endothelial cells
In conclusion, these data demonstrate that SDC4 plays an important role in ECM remodeling. In addition, our findings represent an important step toward understanding the mechanism by which SDC4 can reverse the transformed phenotype of anoikis-resistant endothelial cells.PMID:38591778 | DOI:10.1002/cbin.12158 (Source: Cell Biology International)
Source: Cell Biology International - April 9, 2024 Category: Cytology Authors: Jessica Oyie Sousa Onyeisi Helena Bonciani Nader Carla Cristina Lopes Source Type: research

BMP7-induced osteoblast differentiation requires hedgehog signaling and involves nuclear mechanisms of gene expression control
In conclusion, this study highlights the positive impact of epigenetic control on the expression of genes related to hedgehog signaling during the morphogenetic changes induced by BMP7 signaling in osteoblasts.PMID:38591759 | DOI:10.1002/cbin.12161 (Source: Cell Biology International)
Source: Cell Biology International - April 9, 2024 Category: Cytology Authors: Georgia da Silva Feltran Amanda Fantini de Andrade C élio Jr da C Fernandes Rodrigo A Foganholi da Silva Willian F Zambuzzi Source Type: research

Effects of syndecan-4 silencing on the extracellular matrix remodeling in anoikis-resistant endothelial cells
In conclusion, these data demonstrate that SDC4 plays an important role in ECM remodeling. In addition, our findings represent an important step toward understanding the mechanism by which SDC4 can reverse the transformed phenotype of anoikis-resistant endothelial cells.PMID:38591778 | DOI:10.1002/cbin.12158 (Source: Cell Biology International)
Source: Cell Biology International - April 9, 2024 Category: Cytology Authors: Jessica Oyie Sousa Onyeisi Helena Bonciani Nader Carla Cristina Lopes Source Type: research

BMP7-induced osteoblast differentiation requires hedgehog signaling and involves nuclear mechanisms of gene expression control
In conclusion, this study highlights the positive impact of epigenetic control on the expression of genes related to hedgehog signaling during the morphogenetic changes induced by BMP7 signaling in osteoblasts.PMID:38591759 | DOI:10.1002/cbin.12161 (Source: Cell Biology International)
Source: Cell Biology International - April 9, 2024 Category: Cytology Authors: Georgia da Silva Feltran Amanda Fantini de Andrade C élio Jr da C Fernandes Rodrigo A Foganholi da Silva Willian F Zambuzzi Source Type: research

Effects of syndecan-4 silencing on the extracellular matrix remodeling in anoikis-resistant endothelial cells
In conclusion, these data demonstrate that SDC4 plays an important role in ECM remodeling. In addition, our findings represent an important step toward understanding the mechanism by which SDC4 can reverse the transformed phenotype of anoikis-resistant endothelial cells.PMID:38591778 | DOI:10.1002/cbin.12158 (Source: Cell Biology International)
Source: Cell Biology International - April 9, 2024 Category: Cytology Authors: Jessica Oyie Sousa Onyeisi Helena Bonciani Nader Carla Cristina Lopes Source Type: research

L-kynurenine and quinolinic acid inhibited markers of cell survival in B16 F10 melanoma cells in vitro
Cell Biol Int. 2024 Apr 3. doi: 10.1002/cbin.12163. Online ahead of print.ABSTRACTMelanoma is an aggressive malignancy and remains a major cause of skin cancer mortality, highlighting the need for new treatment strategies. Recent findings revealed that L-kynurenine and quinolinic acid induce cytotoxicity and morphological changes in B16 F10 melanoma cells in vitro. This paper highlights the effects of L-kynurenine and quinolinic acid at previously determined half-maximal inhibitory concentrations on cell cycle progression, cell death and extracellular signal-regulated protein kinase inhibition. Melanoma, B16 F10 and murine...
Source: Cell Biology International - April 4, 2024 Category: Cytology Authors: Charlise Basson June Cheptoo Serem Priyesh Bipath Yvette Nkondo Hlophe Source Type: research

L-kynurenine and quinolinic acid inhibited markers of cell survival in B16 F10 melanoma cells in vitro
Cell Biol Int. 2024 Apr 3. doi: 10.1002/cbin.12163. Online ahead of print.ABSTRACTMelanoma is an aggressive malignancy and remains a major cause of skin cancer mortality, highlighting the need for new treatment strategies. Recent findings revealed that L-kynurenine and quinolinic acid induce cytotoxicity and morphological changes in B16 F10 melanoma cells in vitro. This paper highlights the effects of L-kynurenine and quinolinic acid at previously determined half-maximal inhibitory concentrations on cell cycle progression, cell death and extracellular signal-regulated protein kinase inhibition. Melanoma, B16 F10 and murine...
Source: Cell Biology International - April 4, 2024 Category: Cytology Authors: Charlise Basson June Cheptoo Serem Priyesh Bipath Yvette Nkondo Hlophe Source Type: research

L-kynurenine and quinolinic acid inhibited markers of cell survival in B16 F10 melanoma cells in vitro
Cell Biol Int. 2024 Apr 3. doi: 10.1002/cbin.12163. Online ahead of print.ABSTRACTMelanoma is an aggressive malignancy and remains a major cause of skin cancer mortality, highlighting the need for new treatment strategies. Recent findings revealed that L-kynurenine and quinolinic acid induce cytotoxicity and morphological changes in B16 F10 melanoma cells in vitro. This paper highlights the effects of L-kynurenine and quinolinic acid at previously determined half-maximal inhibitory concentrations on cell cycle progression, cell death and extracellular signal-regulated protein kinase inhibition. Melanoma, B16 F10 and murine...
Source: Cell Biology International - April 4, 2024 Category: Cytology Authors: Charlise Basson June Cheptoo Serem Priyesh Bipath Yvette Nkondo Hlophe Source Type: research