Association of Dental Infections with Intracranial Atherosclerotic Stenosis
Introduction: Periodontal disease (PD) and dental caries are oral infections leading to tooth loss that are associated with atherosclerosis and cerebrovascular disease. We assessed the hypothesis that PD and caries are associated with asymptomatic intracranial atherosclerosis (ICAS) in the Atherosclerosis Risk in Communities (ARIC) study.
Methods: Full-mouth clinical periodontal measurements (7-indices) collected at 6 sites per tooth from 6155 subjects from the Dental Atherosclerosis Risk in Communities Study (DARIC) without prior stroke were used to differentiate seven periodontal disease stages (PPC-I to VII) and dental...
Source: Cerebrovascular Diseases - April 28, 2023 Category: Neurology Source Type: research
Increased Serum EphrinA1 Is Associated With Parenchymal Hematoma (PH) After Ischemic Stroke
Conclusion
Higher serum EphrinA1 is independently associated with higher risk of PH after ischemic stroke. Future studies with larger sa mple size are needed to validate our findings and elucidate the potential role of EphrinA1 in PH. (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - April 27, 2023 Category: Neurology Source Type: research
Red Cell Distribution Width-to-Platelet Count Ratio: A Promising Predictor of In-Hospital All-Cause Mortality in Critically Ill Patients with Acute Ischemic Stroke
Conclusions: RPR showed a nonlinear relationship with in-hospital all-cause mortality in patients with critical AIS.Cerebrovasc Dis (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - April 21, 2023 Category: Neurology Source Type: research
Distinguishing intracranial diabetes-related atherosclerotic plaques : A high-resolution MRI-based radiomics study
Introduction: Diabetes markedly affects the formation and development of intracranial atherosclerosis. The study was aimed at evaluating whether radiomics features can help distinguish plaques primarily associated with diabetes.
Materials and Methods: We retrospectively analyzed patients who were admitted to our center because of acute ischemic stroke due to intracranial atherosclerosis between 2016 and 2022. Clinical data, blood biomarkers, conventional plaque features and plaque radiomics features were collected for all patients. Odds ratios (ORs) with 95% confidence intervals (CIs) were determined from logistic regress...
Source: Cerebrovascular Diseases - April 12, 2023 Category: Neurology Source Type: research
Ayurvedic Treatment in the Rehabilitation of Ischemic Stroke Patients in India: A Randomized Controlled Trial (RESTORE) study protocol
Background: In patients with ischemic stroke, motor and sensory impairments are common and are associated with functional disability. Conventional physiotherapy (CP) is the primary modality of rehabilitation for post-stroke sensorimotor dysfunction. Ayurveda is a commonly practiced alternative system of medicine that offers unique rehabilitative measures for post-stroke recovery.
Hypothesis: We hypothesize that Ayurvedic rehabilitative treatment (ART) is superior to similar duration CP in improving the sensorimotor recovery of patients with ischemic stroke at 90 days after enrollment.
Design: AyuRvedic TrEatment in the R...
Source: Cerebrovascular Diseases - April 6, 2023 Category: Neurology Source Type: research
Comparison of Prasugrel and Clopidogrel in Thrombotic Stroke Patients with Risk Factors for Ischemic Stroke Recurrence: An Integrated Analysis of PRASTRO-I, PRASTRO-II, and PRASTRO-III
Conclusions: This integrated analysis supports the findings of PRASTRO-III. Prasugrel is a promising treatment that results in a numerical reduction in the composite incidence of ischemic stroke, MI, and death from other vascular causes in patients with ischemic stroke who are at a high risk of stroke recurrence. No major safety issues were observed for prasugrel.Cerebrovasc Dis (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - April 3, 2023 Category: Neurology Source Type: research
Culprit plaques of large parent arteries, rather than cerebral small vessel disease, contribute to early neurological deterioration in stroke patients with intracranial branch atheromatous disease
This study aimed to explore the association between culprit plaques of large parent arteries, neuroimaging markers of cerebral small vessel disease (CSVD), and the risk of early neurological deterioration (END) in stroke patients with BAD.
Methods: A total of 97 stroke patients with BAD in the vascular territories of the lenticulostriate arteries or paramedian pontine arteries, diagnosed using high-resolution magnetic resonance imaging (HRMRI), were prospectively recruited in this observational study. A culprit plaque in the middle cerebral artery was defined as the only arterial plaque on the ipsilateral side of an infar...
Source: Cerebrovascular Diseases - March 30, 2023 Category: Neurology Source Type: research
Endothelial dysfunction and parenchymal hematoma in ischemic stroke patients after endovascular thrombectomy
Conclusions: This study demonstrated that ED might be related to PH. Introducing the ED score could increase the reliability of PH risk model for stroke patients treated with EVT. (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - March 27, 2023 Category: Neurology Source Type: research
The Effect of Mechanical Thrombectomy on the Incidence of Poststroke Cognitive Impairment: A Systematic Review of Inhomogeneous Literature
Conclusions: The incidence of PSCI is lower in MT patients than in the control group.Cerebrovasc Dis (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - March 23, 2023 Category: Neurology Source Type: research
High Neutrophil-to-Lymphocyte Ratio Predicts One-Year Risk of Pneumonia Post-Stroke Discharge
Conclusion: The NLR could predict the risk of post-stroke pneumonia up to 1 year after discharge from acute stroke care. It may help identify high-risk stroke survivors, for whom appropriate interventions can be targeted.Cerebrovasc Dis (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - March 23, 2023 Category: Neurology Source Type: research
The frequency of CYP2C19 loss-of-function variants in patients with non-cardioembolic ischemic stroke or transient ischemic attack in the Dutch population
Discussion and conclusion: About a quarter of patients with non-cardioembolic ischemic stroke or TIA in the Dutch population carry a CYP2C19 LOF variant. This is lower than estimates found in studies with Asian populations, but similar to estimates found among Caucasian patients in other parts of the world. (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - March 22, 2023 Category: Neurology Source Type: research
Long sleep duration and dissatisfaction with sleep quality are associated with ischemic stroke in young patients
Introduction: Suboptimal sleep duration and poor sleep quality have been proposed to increase stroke risk. However, their significance in young ischemic stroke is unclear. We aimed to investigate the importance of sleep duration and quality on young ischemic stroke patients.
Methods: A multicenter matched case-control study was performed to evaluate under-recognized risk factors in young ( (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - March 21, 2023 Category: Neurology Source Type: research
Headache in Pediatric Moyamoya Disease after Revascularization Surgery
Conclusion: Headaches often persist or newly develop after revascularization surgery in MMD patients. Accompanying nausea or vomiting and occurrence upon awakening are characteristic features. Postoperative headache does not necessarily imply insufficient disease control.Cerebrovasc Dis (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - March 21, 2023 Category: Neurology Source Type: research
Impact of Long-Term Antithrombotic and Statin Therapy on the Clinical Outcome in Patients with Cavernous Malformations of the Central Nervous System: A Single-Center Case Series of 428 Patients
Conclusion: The results of our study provide further evidence that antithrombotic therapy alone or in combination with statins in patients with CMs of the central nervous system does not increase the risk of hemorrhage or focal neurological deficit but, on the contrary, may have some benefit.Cerebrovasc Dis (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - March 21, 2023 Category: Neurology Source Type: research
Prevalence and incidence of Carotid-Fetal-Posterior syndrome
Discussion/Co nclusion: CFP syndrome has a low incidence and low prevalence among symptomatic carotid stenosis cases. Given lower prevalence of CFP syndrome among referred cases than local, CFP-syndrome seems susceptible to underdiagnosis. On the other hand, few cases with suspicion of CFP syndrome had CFP syndro me, why CFP syndrome also seems susceptible to overdiagnosis if detailed assessment is not employed. (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - March 15, 2023 Category: Neurology Source Type: research
