Comparative Study of Cerebral Venous Thrombosis-risk factors, clinical course and outcome in Subjects with and without Covid-19 infection
Conclusion: COVID-CVT patients were male predominant and of older age, with higher hospital stay, and h igher inpatient mortality as compared to non-covid CVT patients. (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - April 25, 2023 Category: Neurology Source Type: research

Artificial Intelligence-Assisted Software Significantly Decreases All Workflow Metrics for Large Vessel Occlusion Transfer Patients, within a Large Spoke and Hub System
Conclusion: Within our spoke and hub system, Viz LVO significantly decreased all workflow metrics for patients who were transferred from spokes with versus without Viz. (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - February 14, 2023 Category: Neurology Source Type: research

Artificial intelligence-assisted software significantly decreases all workflow metrics for large vessel occlusion transfer patients, within a large spoke and hub system
Background: Artificial intelligence (AI) software is increasingly applied in stroke diagnostics. Viz LVO (large vessel occlusion) is an AI-based software that is FDA-approved for LVO detection in CT Angiography (CTA) scans. We sought to investigate differences in transfer times [from peripheral (spoke) to central (hub) hospitals] for LVO patients between spoke hospitals that utilize Viz LVO and those that do not. Methods: In this retrospective cohort study, we used our institutional database to identify all suspected/confirmed LVO transferred patients from spokes (peripheral hospitals) within and outside of our healthc...
Source: Cerebrovascular Diseases Extra - February 14, 2023 Category: Neurology Source Type: research

Soluble ST2 Predicts Poor Functional Outcome in Acute Ischemic Stroke Patients
Conclusion: Evaluation of sST2 may act as a reliable biomarker of functional outcome in AIS.Cerebrovasc Dis Extra 2023;13:33 –40 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - February 8, 2023 Category: Neurology Source Type: research

Soluble ST2 Predicts Poor Functional Outcome in Acute Ischemic Stroke Patients
Conclusion: Evaluation of soluble ST2 may act as a reliable biomarker of functional outcome in AIS. (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - February 8, 2023 Category: Neurology Source Type: research

A Pilot Study of Application of the Stroke Riskometer Mobile App for Assessment of the Course and Clinical Outcomes of COVID-19 among Hospitalized Patients
Conclusions: High risk of stroke, physical inactivity, alcohol intake, high SBP, and atrial fibrillation are associated with severity and mortality of COVID-19. Our findings suggest that the Stroke Riskometer app could be used as a simple predictive tool of COVID-19 severity and mortality. (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - January 26, 2023 Category: Neurology Source Type: research

A pilot study of application of the Stroke Riskometer mobile app for assessment of the course and clinical outcomes of COVID-19 among hospitalised patients
Conclusions: High risk of stroke, physical inactivity, alcohol intake, high SBP, and atrial fibrillation are associated with severity and mortality of COVID-19 . Our findings suggest that the Stroke Riskometer app could be used as a simple predictive tool of COVID-19 severity and mortality. (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - January 26, 2023 Category: Neurology Source Type: research

Evaluation of Microvascular Rarefaction in Vascular Cognitive Impairment and Heart Failure (CRUCIAL): Study Protocol for an Observational Study
Discussion: CRUCIAL will examine the pathophysiological role of microvascular rarefaction in VCI and HFpEF using advanced brain and cardiac MRI techniques. Furthermore, we will investigate surrogate biomarkers for non-invasive, faster, easier, and cheaper assessment of microvascular density since these are more likely to be disseminated into widespread clinical practice. If microvascular rarefaction is an early marker of developing small vessel diseases, then measuring rarefaction may allow preclinical diagnosis, with implications for screening, risk stratification, and prevention. Further knowledge of the relevance of mic...
Source: Cerebrovascular Diseases Extra - January 16, 2023 Category: Neurology Source Type: research

Evaluation of miCRovascular rarefaction in vascUlar Cognitive Impairment and heArt faiLure (CRUCIAL): Study protocol for an observational study
Discussion: CRUCIAL will examine the pathophysiological role of microvascular rarefaction in VCI and HFpEF using advanced brain and cardiac MRI techniques. Furthermore, we will investigate surrogate biomarkers for non-invasive, faster, easier, and cheaper assessment of microvascular density since these are more likely to be disseminated into widespread clinical practice. If microvascular rarefaction is an early marker of developing small vessel diseases, then measuring rarefaction may allow pre-clinical diagnosis, with implications for screening, risk stratification, and prevention. Further knowledge of the relevance of mi...
Source: Cerebrovascular Diseases Extra - January 16, 2023 Category: Neurology Source Type: research

Predicting Atrial Fibrillation after Ischemic Stroke: Clinical, Genetics, and Electrocardiogram Modelling
Conclusion: We demonstrated that a model combining clinical and electrocardiographic variables provided robust prediction of AF in our post-stroke population. Role of SNP in prediction of AF was limited.Cerebrovasc Dis Extra 2023;13:9 –17 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - December 15, 2022 Category: Neurology Source Type: research

Predicting Atrial Fibrillation after Ischemic Stroke: Clinical, Genetics, and Electrocardiogram Modelling
Conclusion: We demonstrated that a model combining clinical and electrocardiographic variables provided robust prediction of AF in our post-stroke population. Role of SNP in prediction of AF was limited. (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - December 15, 2022 Category: Neurology Source Type: research

Predicting atrial fibrillation after ischemic stroke: clinical, genetics and electrocardiogram modelling
Introduction: Detection of atrial fibrillation (AF) is challenging in patients after ischemic stroke due to its paroxysmal nature. We aim to determine the utility of a combined clinical, electrocardiographic and genetic variables model to predict AF in a post-stroke population. Materials and Methods: We performed a cohort study at a single comprehensive stroke centre from 09/11/2009 to 31/10/2017. All patients recruited were diagnosed with acute ischemic stroke or transient ischemic attacks. Electrocardiographic variables including p-wave terminal force (PWTF), corrected QT interval (QTc) and genetic variables including ...
Source: Cerebrovascular Diseases Extra - December 15, 2022 Category: Neurology Source Type: research

Carotid endarterectomy for symptomatic carotid stenosis: differences in patient profile in a Low-Middle Income Country
Conclusion: There is a delay in patients undergoing CEA for symptomatic carotid stenosis. Majority have high grade stenosis and present late only after a stroke reflecting a lack of awareness. CEA can be performed safely even in patients with significant intracranial tandem stenosi s and contralateral carotid occlusion. (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - December 8, 2022 Category: Neurology Source Type: research

Impact of Patency of the Carotid Terminus and Middle Cerebral Artery on Early Clinical Outcomes in Patients with Acute Internal Carotid Artery Occlusion and Mild Symptoms
Conclusion: The overall clinical outcomes of patients with acute ICAO with mild symptoms were not depending on the patency of the ICT and MCA, but initial treatment with IVT alone might risk unfavorable outcomes due to thrombus migration in patients with patent ICT and MCA.Cerebrovasc Dis Extra 2023;13:1 –7 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - October 24, 2022 Category: Neurology Source Type: research