Compound Shenma Jingfu granule alleviates cerebral ischemia via HIF-1 α-mediated promotion of angiogenesis
Shenma Jingfu Granule, a traditional Chinese medicine formula, has been used clinically for the treatment of cerebral circulation insufficiency. However, the mechanism involved in alleviating cerebral ischemia... (Source: Chinese Medicine)
Source: Chinese Medicine - April 10, 2024 Category: Complementary Medicine Authors: Ruihua He, Yi Xu, Jingxue Liu, Jing Liu, Jing Chen, Xufang Wang, Lei Qiu and Jin Huang Tags: Research Source Type: research
Bazi Bushen ameliorates age-related energy metabolism dysregulation by targeting the IL-17/TNF inflammatory pathway associated with SASP
Chronic inflammation and metabolic dysfunction are key features of systemic aging, closely associated with the development and progression of age-related metabolic diseases. Bazi Bushen (BZBS), a traditional C... (Source: Chinese Medicine)
Source: Chinese Medicine - April 9, 2024 Category: Complementary Medicine Authors: Xiaogang Shen, Mengnan Li, Yawen Li, Yuning Jiang, Kunxu Niu, Shixiong Zhang, Xuan Lu, Runtao Zhang, Zhiqin Zhao, Liangxing Zhou, Zhifang Guo, Siwei Wang, Cong Wei, Liping Chang, Yunlong Hou and Yiling Wu Tags: Research Source Type: research
Oleuropein alleviates myocardial ischemia –reperfusion injury by suppressing oxidative stress and excessive autophagy via TLR4/MAPK signaling pathway
Myocardial ischemia/reperfusion injury (MIRI) is an important complication of reperfusion therapy, and has a lack of effective prevention and treatment methods. Oleuropein (OP) is a natural strong antioxidant ... (Source: Chinese Medicine)
Source: Chinese Medicine - April 8, 2024 Category: Complementary Medicine Authors: Jia He, Liting Huang, Kaili Sun, Jilang Li, Shan Han, Xiang Gao, Qin-Qin Wang, Shilin Yang, Wen Sun and Hongwei Gao Tags: Research Source Type: research
NBR1-p62-Nrf2 mediates the anti-pulmonary fibrosis effects of protodioscin
Idiopathic pulmonary fibrosis is a persistent disease of the lung interstitium for which there is no efficacious pharmacological therapy. Protodioscin, a steroidal saponin, possesses diverse pharmacological pr... (Source: Chinese Medicine)
Source: Chinese Medicine - April 8, 2024 Category: Complementary Medicine Authors: Qian Zeng, Bin-bin Wen, Xin Liu, Yong-yu Luo, Zhen-gang Hu, Lei Huang, Xiao-hua Zhang, Xiao-ting Huang, Ting-ting Zhou, Xiao-xue Sang, Yu-yang Luo, Da-yan Xiong, Zi-qiang Luo, Wei Liu and Si-yuan Tang Tags: Research Source Type: research
Danggui Sini decoction alleviates oxaliplatin-induced peripheral neuropathy by regulating gut microbiota and potentially relieving neuroinflammation related metabolic disorder
Danggui Sini decoction (DSD), a traditional Chinese medicine formula, has the function of nourishing blood, warming meridians, and unblocking collaterals. Our clinical and animal studies had shown that DSD can... (Source: Chinese Medicine)
Source: Chinese Medicine - April 7, 2024 Category: Complementary Medicine Authors: Chen Chen, Jian-Lin Xu, Zhan-Cheng Gu, Shan-Shan Zhou, Guo-Li Wei, Jia-Lin Gu, Hai-Long Ma, Yan-Qi Feng, Zi-Wei Song, Zhan-Peng Yan, Shan Deng, Rong Ding, Song-Lin Li and Jie-Ge Huo Tags: Research Source Type: research
Natural products as potential drug treatments for acute promyelocytic leukemia
Acute promyelocytic leukemia (APL), which was once considered one of the deadliest types of leukemia, has become a curable malignancy since the introduction of all-trans retinoic acid (ATRA) and arsenic trioxi... (Source: Chinese Medicine)
Source: Chinese Medicine - April 3, 2024 Category: Complementary Medicine Authors: Jiaxin Chen and Zuoqi Ding Tags: Review Source Type: research
Medicinal plants and natural products for treating overactive bladder
Overactive bladder (OAB) presents a high prevalence of 16 –18% worldwide. The pathophysiology of OAB is still poorly understood while effective therapy or countermeasure are very limited. On the other hand, med... (Source: Chinese Medicine)
Source: Chinese Medicine - March 27, 2024 Category: Complementary Medicine Authors: Huanxian Chen, Maggie Pui Man Hoi and Simon Ming Yuen Lee Tags: Review Source Type: research
Cordyceps sinensis relieves non-small cell lung cancer by inhibiting the MAPK pathway
To determine the pharmacodynamic mechanism underlying Cordyceps sinensis relief in a murine model of non-small cell lung cancer (NSCLC). (Source: Chinese Medicine)
Source: Chinese Medicine - March 25, 2024 Category: Complementary Medicine Authors: Tianming Lu, Lirun Zhou, Zheng Chu, Yang Song, Qixin Wang, Minghong Zhao, Chuanhao Dai, Lin Chen, Guangqing Cheng, Jigang Wang and Qiuyan Guo Tags: Research Source Type: research
Formononetin reverses Treg/Th17 imbalance in immune-mediated bone marrow failure mice by regulating the PI3K/Akt signaling pathway
Severe aplastic anemia (SAA) is a syndrome of bone marrow failure which is life-threatening. Recent studies have demonstrated that CD4 + T cell subsets, including T regulatory (Treg) and T helper 17 (Th17) cel... (Source: Chinese Medicine)
Source: Chinese Medicine - March 25, 2024 Category: Complementary Medicine Authors: Huixuan Lan, Wei Qiu, Jie Wu, Zhijing Hu, Xiaomin Zhang and Lingling Zhu Tags: Research Source Type: research
Total iridoid glycoside extract of Lamiophlomis rotata (Benth) Kudo accelerates diabetic wound healing by the NRF2/COX2 axis
Lamiophlomis rotata (Benth.) Kudo (L. rotata), the oral Traditional Tibetan herbal medicine, is adopted for treating knife and gun wounds for a long time. As previously demonstrated, total iridoid glycoside extra... (Source: Chinese Medicine)
Source: Chinese Medicine - March 22, 2024 Category: Complementary Medicine Authors: Xiaoyu Geng, Ying Wang, Huan Li, Liang Song, Chen Luo, Xiaojie Gu, Haixin Zhong, Huilin Chen, Xinzhu Chen, Jianwei Wang and Zheng Pan Tags: Research Source Type: research
Recent advances in the potential effects of natural products from traditional Chinese medicine against respiratory diseases targeting ferroptosis
Respiratory diseases, marked by structural changes in the airways and lung tissues, can lead to reduced respiratory function and, in severe cases, respiratory failure. The side effects of current treatments, s... (Source: Chinese Medicine)
Source: Chinese Medicine - March 22, 2024 Category: Complementary Medicine Authors: Tian Chen, Lu Ding, Meiru Zhao, Siyu Song, Juan Hou, Xueyan Li, Min Li, Kai Yin, Xiangyan Li and Zeyu Wang Tags: Review Source Type: research
TCMNPAS: a comprehensive analysis platform integrating network formulaology and network pharmacology for exploring traditional Chinese medicine
The application of network formulaology and network pharmacology has significantly advanced the scientific understanding of traditional Chinese medicine (TCM) treatment mechanisms in disease. The field of herb... (Source: Chinese Medicine)
Source: Chinese Medicine - March 22, 2024 Category: Complementary Medicine Authors: Yishu Liu, Xue Li, Chao Chen, Nan Ding, Peiyong Zheng, Xiaoyun Chen, Shiyu Ma and Ming Yang Tags: Research Source Type: research
Chemodiversity, pharmacological activity, and biosynthesis of specialized metabolites from medicinal model fungi Ganoderma lucidum
Ganoderma lucidum is a precious fungus, particularly valued for its dual use as both medicine and food. Ganoderic acids (GAs), the distinctive triterpenoids found in the Ganoderma genus, exhibit a wide range of p... (Source: Chinese Medicine)
Source: Chinese Medicine - March 22, 2024 Category: Complementary Medicine Authors: Yupeng Du, Lixia Tian, Yu Wang, Zhenhao Li and Zhichao Xu Tags: Review Source Type: research
Juglone induces ferroptosis in glioblastoma cells by inhibiting the Nrf2-GPX4 axis through the phosphorylation of p38MAPK
Ferroptosis, a non-apoptotic form of cell death induced by accumulation of free iron ions and lipid peroxidation, its importance for cancer treatment is gradually being recognized. Research on the anti-cancer ... (Source: Chinese Medicine)
Source: Chinese Medicine - March 22, 2024 Category: Complementary Medicine Authors: Fangzhou Guo, Guoyuan Ling, Jianting Qiu, Jicheng Li, Yu Gan, YingYing Yu, Jiamei Tang, Ligen Mo and Haozhe Piao Tags: Research Source Type: research
The combination of Schisandrin C and Luteolin synergistically attenuates hepatitis B virus infection via repressing HBV replication and promoting cGAS-STING pathway activation in macrophages
HBV infection can result in severe liver diseases and is one of the primary causes of liver cell carcinoma-related mortality. Liuwei Wuling tablet (LWWL) is a traditional Chinese medicine formula, with a prote... (Source: Chinese Medicine)
Source: Chinese Medicine - March 18, 2024 Category: Complementary Medicine Authors: Zhixin Wu, Xiaomei Zhao, Ruisheng Li, Xinru Wen, Ye Xiu, Minjuan Long, Junjie Li, Xiuqin Huang, Jincai Wen, Xu Dong, Yingjie Xu, Zhaofang Bai, Xiaoyan Zhan and Xiaohe Xiao Tags: Research Source Type: research
