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Response to letter to the editor: efficacy of sodium hypochlorite and chlorhexidine against Enterococcus faecalisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - November 20, 2009 Category: Dentistry Source Type: journals

In vitro antifungal action of different substances over microwaved-cured acrylic resinsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study evaluated the antifungal action of different agents over microwave-cured acrylic resin without polishing specimens previously contaminated with Candida albicans. MATERIAL AND METHODS: Sixty specimens were immersed in BHI broth previously inoculated with the yeast and stored for 3 h at 37ºC. They were divided into 5 experimental groups (n=10): G1: 2% chlorhexidine solution (10 min); G2: 0.5% sodium hypochlorite (10 min); G3: modified sodium hypochlorite (10 min); G4: effervescent agent (5 min); G5: hydrogen peroxide 10v (30 min). The specimens of the control group 1 (C1) were not disinfected. Ten additional spec...
Source: Journal of Applied Oral Science - November 20, 2009 Category: Dentistry Source Type: journals

Impact of chlorhexidine mouth rinse use on postextraction infection via nitric oxide pathwayEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Results indicated that good oral hygiene following periodontal treatment prior to third molar surgery was related to an increase in arginase activity, which may improve wound healing. However, use of CHX rinse following periodontal treatment had no pronounced effect on the arginase–NO pathway. Content Type Journal ArticleCategory Original Research PaperDOI 10.1007/s00011-009-0115-6Authors Nurdan Ozmeric, Gazi University Department of Periodontology, Faculty of Dentistry Biskek caddesi 84. sokak, Emek 06510 Ankara TurkeyNur Mollaoglu, Gazi University Oral and Maxillofacial Surgery, Faculty...
Source: Inflammation Research - November 18, 2009 Category: Research Tags: Inflammation Research Source Type: journals

Determination of Chlorhexidine in Saliva and in Aqueous SolutionsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Caries Res 1991;25:410-414 (DOI:10.1159/000261403) (Source: Caries Research)
Source: Caries Research - November 17, 2009 Category: Dentistry Source Type: journals

A study of the relation between erosion and microhardness of root canal dentinEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: It can be concluded that erosion is not the main factor in decreasing the dentin microhardness, whereas the amount of irrigant penetration might be the main cause. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - November 14, 2009 Category: ENT & OMF Authors: Mohammad Ali Saghiri, Abbas Delvarani, Payman Mehrvarzfar, Golnaz Malganji, Mehrdad Lotfi, Bahareh Dadresanfar, Ali Mohammad Saghiri, Sahar Dadvand Tags: Online Only Articles Source Type: journals

Does the Type of Skin Marker Prevent Marking Erasure of Surgical-Site Markings?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Do certain skin marking pens withstand skin preparation with a chlorhexidine-based skin preparation solution in a manner similar to that with an iodine-based solution? ePlasty, Open Access Journal of Plastic Surgery (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - November 13, 2009 Category: Surgery Tags: Plastic Surgery & Aesthetic Medicine Source Type: info

Antimicrobial efficacy of eucalyptus oil and 1,8-cineole alone and in combination with chlorhexidine digluconate against microorganisms grown in planktonic and biofilm culturesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions In conclusion, CHG may be combined with either crude EO or its major component 1,8-cineole for enhanced, synergistic antimicrobial activity against a wide range of microorganisms in planktonic and biofilm modes of growth; however, the superior antimicrobial efficacy associated with crude EO alone, compared with 1,8-cineole, favours its combination with CHG. (Source: Journal of Antimicrobial Chemotherapy)
Source: Journal of Antimicrobial Chemotherapy - November 10, 2009 Category: Microbiology Authors: Hendry, E. R., Worthington, T., Conway, B. R., Lambert, P. A. Tags: Original research Source Type: journals

Characterization of a polyurethane based controlled release system for local delivery of chlorhexidine diacetate.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, the polyurethane based system developed in this study is potentially useful as a local delivery system for CDA and could be used not only in surgery but also in dental and clinical applications. PMID: 19909814 [PubMed - as supplied by publisher] (Source: European Journal of Pharmaceutics and Biopharmaceutics)
Source: European Journal of Pharmaceutics and Biopharmaceutics - November 9, 2009 Category: Drugs & Pharmacology Authors: Huynh TT, Padois K, Sonvico F, Rossi A, Zani F, Pirot F, Doury J, Falson F Tags: Eur J Pharm Biopharm Source Type: journals

Parotid gland swelling following mouthrinse useEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Swelling of the parotid gland following use of a mouthwash has previously been reported, although previous reports found this side effect only in patients who used chlorhexidine mouthwashes. This complication has therefore been informally linked to chlorhexidine. The present case report questions this hypothesis and suggests that parotid gland swelling may not be related to the type of mouthwash used, but may instead be a consequence of the rinsing action itself. (Source: International Journal of Dental Hygiene)
Source: International Journal of Dental Hygiene - November 2, 2009 Category: Dentistry Authors: GA Van der Weijden, JMAG ten Heggeler, DE Slot, NAM Rosema, U Van der Velden Source Type: journals

Evaluating central venous catheter care in a pediatric intensive care unit.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: The results of this project suggest that infection control efforts may be most appropriately focused on processes rather than on products. PMID: 19880953 [PubMed - in process] (Source: American Journal of Critical Care)
Source: American Journal of Critical Care - November 1, 2009 Category: Nursing Authors: Hatler C, Buckwald L, Salas-Allison Z, Murphy-Taylor C Tags: Am J Crit Care Source Type: journals

Effectiveness of 0.50% and 0.75% chlorhexidine dentifrices in orthodontic patients: A double-blind and randomized controlled trialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: This study suggests that the use of dentifrices with lower concentration of chlorhexidine can reduce the risk of tooth staining without compromising its effectiveness in controlling gingivitis and bleeding in orthodontic patients. (Source: American Journal of Orthodontics and Dentofacial Orthopedics)
Source: American Journal of Orthodontics and Dentofacial Orthopedics - November 1, 2009 Category: Dentistry Authors: Paula Vanessa Pedron Oltramari-Navarro, Juliana Mára Titarelli, Juliane Avansini Marsicano, José Fernando Castanha Henriques, Guilherme Janson, José Roberto Pereira Lauris, Marília Afonso Rabelo Buzalaf Tags: Original Articles Source Type: journals

Editor's choiceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The value of chlorhexidine in clinical dentistry has led to many applications, including varnishes, mouthwashes, sprays, chewing gums, and dentifrices. However, at some common concentrations, it can cause staining, especially in orthodontic patients. The aim of this study was to determine whether a lower concentration of chlorhexidine in dentifrices (0.50% or 0.75%) could reduce the risk of tooth staining without compromising its effectiveness for gingivitis, bleeding, and plaque prevention. For the best possible results, this was a double-blind, randomized controlled trial. Fulfilling the inclusion criteria, 81 volunteers...
Source: American Journal of Orthodontics and Dentofacial Orthopedics - November 1, 2009 Category: Dentistry Authors: David L. Turpin Tags: Frontmatter Source Type: journals

Adjunctive cavity disinfectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The Atraumatic Restorative Treatment (ART) approach was developed to enable practitioners in countries with limited oral health care systems to provide preventive and restorative dental care. It has also been shown to be cost-effective compared to traditional methods using amalgam and provides durable single-surface restorations in primary and permanent posterior teeth. Egypt has a particularly high prevalence and severity of dental caries among its younger population. The high number of caries is attributed to poor oral hygiene, minimal preventive care, financial barriers to the provision and receipt of care, poorly distr...
Source: Dental Abstracts - November 1, 2009 Category: Dentistry Tags: ART Therapy Source Type: journals

Chlorhexidine urticaria: A rare occurrence with a common mouthwashEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Sharma Anamika, Chopra HarneetIndian Journal of Dental Research 2009 20(3):377-379Chlorhexidine is a widely used antiseptic and disinfectant in medical and nonmedical environments. Compared to its ubiquitous use, allergic contact dermatitis from chlorhexidine has rarely been reported and so its sensitization rate seems to be low. The prevalence of contact urticaria and anaphylaxis due to chlorhexidine remains to be unknown. This case report presents a case of urticaria due to oral use of chlorhexidine. The adverse reaction was confirmed by skin prick test. (Source: Table of Contents : Indian Journal of Dental Research : 2006 - 17(3))
Source: Table of Contents : Indian Journal of Dental Research : 2006 - 17(3) - October 31, 2009 Category: Dentistry Authors: Sharma Anamika, Chopra Harneet Source Type: journals

Antimicrobial effect of MTAD, Tetraclean, Cloreximid, and sodium hypochlorite on three common endodontic pathogensEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion:</b> 5.25% NaOCl showed a high antimicrobial activity against anaerobic bacteria. MTAD and Tetraclean showed a high action against both, strictly anaerobic and facultative anaerobic bacteria. Chlorexidine + Cetrimide (Cloreximid) showed the lowest antibacterial activity against both, facultative and strictly anaerobic bacteria tested. (Source: Table of Contents : Indian Journal of Dental Research : 2006 - 17(3))
Source: Table of Contents : Indian Journal of Dental Research : 2006 - 17(3) - October 31, 2009 Category: Dentistry Authors: Giardino Luciano, Savoldi Enrico, Ambu Emanuele, Rimondini Roberto, Palezona Alberto, Debbia Eugenio A Source Type: journals

Burns (minor thermal)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
New evidence; conclusion confirmed for: Alginate dressing One systematic review added (search date 2008), which found no RCTs that met Clinical Evidence inclusion criteria. Categorisation unchanged (Unknown effectiveness). Chlorhexidine-impregnated paraffin gauze dressing One systematic review added (search date 2008), which did not pool data, and found no additional RCTs to those previously reported in this Clinical Evidence review. Categorisation unchanged (Unknown effectiveness). Foam dressing One systematic review added (search date 2008),which found no RCTs...
Source: Clinical Evidence - October 27, 2009 Category: Journals (General) Source Type: journals

In vitro evaluation of effect of various endodontic solutions on selected physical properties of white mineral trioxide aggregateEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
During endodontic therapy various irrigating solutions at different concentrations and duration are used. These chemical solutions may affect the setting reaction of mineral trioxide aggregate (MTA). The aim of this study was to evaluate the effect of sodium hypochlorite (NaOCl) (5.25%), chlorhexidine gluconate (CHX) (2%), ethylenediaminetetraacetic acid (EDTA) solution (17%) and BioPure MTAD on surface micro-hardness and flexural strength of white MTA. Twenty-five disk-shaped and 25 bar-shaped specimens were divided into five groups and were stored under distilled water, NaOCl (5.25%), chlorhexidine CHX (2%), EDTA solutio...
Source: Australian Endodontic Journal - October 22, 2009 Category: Dentistry Authors: Vivek Aggarwal, Anurag Jain, Debipada Kabi Source Type: journals

Chlorhexidine Vaginal and Infant Wipes May Not Prevent Neonatal SepsisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In a randomized trial, use of vaginal and infant wipes soaked in chlorhexidine did not prevent neonatal sepsis or mother-infant transmission of pathogenic bacteria. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 22, 2009 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health Source Type: news

Impact of 4.0% chlorhexidine cleansing of the umbilical cord on mortality and omphalitis among newborns of Sylhet, Bangladesh: design of a community-based cluster randomized trialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
DiscussionDue to report in early 2010, the Projahnmo Chlorhexidine Study examines the impact of multiple or single chlorhexidine cleansing of the cord on neonatal mortality and omphalitis among newborns of rural Sylhet District, Bangladesh. The results of this trial will be interpreted in conjunction with a similarly designed trial previously conducted in Nepal, and will have implications for policy guidelines for optimal cord care of newborns in low resource settings in Asia. (Source: BMC Pediatrics - Latest articles)
Source: BMC Pediatrics - Latest articles - October 20, 2009 Category: Pediatrics Authors: Luke MullanyShams El ArifeenPeter WinchRasheduzzaman ShahIshtiaq MannanSyed RahmanMohammad RahmanGary DarmstadtSaifuddin AhmedMathuram SantoshamRobert BlackAbdullah Baqui Source Type: journals

Effect of Microbicidal Wipes on Neonatal Sepsis AssessedEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Chlorhexidine vaginal and neonatal wipes are ineffective in preventing sepsis and bacterial colonization of newborns, according to a study published online Oct. 20 in The Lancet. (Source: Modern Medicine)
Source: Modern Medicine - October 19, 2009 Category: Journals (General) Source Type: info

Patients with Long-term Oral Carriage Harbor High-persister Mutants of C. albicans.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study suggests persister cells are clinically relevant, and antimicrobial therapy selects for high persister strains in vivo. Drug tolerance of persisters may be a critical, but overlooked component responsible for antimicrobial drug failure and relapsing infections. PMID: 19841146 [PubMed - as supplied by publisher] (Source: Antimicrobial Agents and Chemotherapy)
Source: Antimicrobial Agents and Chemotherapy - October 18, 2009 Category: Microbiology Authors: Lafleur MD, Qi Q, Lewis K Tags: Antimicrob Agents Chemother Source Type: journals

Antimicrobial agents used in the control of periodontal biofilms: effective adjuncts to mechanical plaque control?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The control of biofilm accumulation on teeth has been the cornerstone of periodontal disease prevention for decades. However, the widespread prevalence of gingivitis suggests the inefficiency of self-performed mechanical plaque control in preventing gingival inflammation. This is particularly relevant in light of recent evidence suggesting that long standing gingivitis increases the risk of loss of attachment and that prevention of gingival inflammation might reduce the prevalence of mild to moderate periodontitis. Several antimicrobials have been tested as adjuncts to mechanical plaque control in order to improve the resu...
Source: Brazilian Oral Research - October 16, 2009 Category: Dentistry Source Type: journals

Skin disinfection methods: prospective evaluation and postimplementation results.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: In this study, isopropyl alcohol and chlorhexidine disinfectants were more efficacious than isopropyl alcohol and iodine. There was no difference in efficacy between one-step and two-step procedures or between methods of application. A one-step chlorhexidine and isopropyl alcohol kit has been successfully implemented at CBS. PMID: 19821950 [PubMed - as supplied by publisher] (Source: Transfusion)
Source: Transfusion - October 9, 2009 Category: Hematology Authors: Ramirez-Arcos S, Goldman M Tags: Transfusion Source Type: journals

Antimicrobial central venous catheters in adults: a systematic review and meta-analysisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: DARE Area: Evidence > Disease Focused Reviews CRD Summary: This review assessed the efficacy of antimicrobial central venous catheters in adults, concluding that chlorhexidine-silver sulfadiazine or minocycline-rifampicin central venous catheters can be considered when the baseline incidence of catheter-related bloodstream infections is above institutional goals. The authors' conclusions reflect the limitations of the evidence and are likely to be reliable. CRD Commentary: This review addressed a clear question and undertook a thorough search for studies with no language restrictions. No evidence of publication ...
Source: NeLM - Disease Focused Reviews - October 8, 2009 Category: Internal Medicine Source Type: organizations

Pilot trial to compare tolerance of chlorhexidine gluconate to povidone-iodine antisepsis for central venous catheter placement in neonatesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
& M C Harris (Source: Journal of Perinatology)
Source: Journal of Perinatology - October 7, 2009 Category: Perinatology & Neonatology Authors: J S GarlandC P AlexM R UhingI E PetersideA RentzM C Harris Source Type: journals

Prevention of Bloodstream Infections by Use of Daily Chlorhexidine Baths for Patients at a Long‐Term Acute Care Hospital • Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. Daily chlorhexidine baths appeared to be an effective intervention to reduce rates of CVC‐associated BSI in an LTACH. (Source: Infect Control Hosp Epidemiol Latest Issue)
Source: Infect Control Hosp Epidemiol Latest Issue - October 7, 2009 Category: Epidemiology Tags: article Original Article Source Type: journals

The Effect of Daily Bathing With Chlorhexidine on the Acquisition of Methicillin-Resistant Staphylococcus Aureus, Vancomycin-Resistant Enterococcus, and Healthcare-Associated Bloodstream Infections: Results of a Quasi-Experimental Multicenter TrialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Investigators sought to determine whether daily chlorhexidine bathing decreases the incidence of colonization and BSI because of MRSA and VRE among ICU patients. Critical Care Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 7, 2009 Category: Consumer Health News Tags: Critical Care Source Type: news

Study Shows DuraPrep Solution May Be Superior To Chlorhexidine In Preventing Surgical-Site InfectionsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
3M Health Care today announced the publication of a new independent study "Effects of Preoperative Skin Preparation on Postoperative Wound Infection Rates: A Prospective Study of 3 Skin Preparation Protocols," that compared the effects of three different skin preparation solutions on surgical-site infections. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 7, 2009 Category: Consumer Health News Tags: Dermatology Source Type: news

Mechanisms of the inhibition of endplate acetylcholine receptors by antiseptic chlorhexidine (experiments and models)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Mechanisms of the inhibition of evoked multiquantal endplate currents (EPC) by chlorhexidine (CHX) were studied in electrophysiological experiments and by mathematical modeling to discriminate between possible channel, receptor, and non-receptor effects of this common antiseptic drug. Experiments were carried out on the isolated neuromuscular preparation of the cut m. sartorius of the frog Rana ridibunda. The nerve-stimulation-evoked endplate currents were measured by standard double microelectrode technique. For the mathematical simulation, a method based on the solution of a system of ordinary dif...
Source: Naunyn-Schmiedeberg's Archives of Pharmacology - October 6, 2009 Category: Drugs & Pharmacology Tags: Naunyn-Schmiedeberg's Archives of Pharmacology Source Type: journals

Study of DuraPrep versus chlorhexidineEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(WeissComm Partners) A new independent study found that Iodophor-based skin preparation solutions may be superior to chlorhexidine in preventing surgical-site infections. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 5, 2009 Category: Global & Universal Source Type: news

Correct use of chlorhexidine in intravenous practice.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article reviews the routes by which microorganisms may contaminate vascular access devices, and examines the role of chlorhexidine in the prevention of catheter-related bloodstream infections. Chlorhexidine-based cleansing products for use in intravenous therapy are reviewed and their correct use is discussed, with reference to clinical guidelines. PMID: 19911612 [PubMed - in process] (Source: Nursing Standard)
Source: Nursing Standard - October 3, 2009 Category: Nursing Authors: Scales K Tags: Nurs Stand Source Type: journals

FIGHT BAC (Chlorhexidine Gluconate) Aerosol [Deep Valley Farm, Inc.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Updated Date: Oct 2, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - October 2, 2009 Category: Drugs & Pharmacology Source Type: organizations

Transdentinal cytotoxic effects of different concentrations of chlorhexidine gel applied on acid-conditioned dentin substrate.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
It has been demonstrated that chlorhexidine digluconate (CHX) is capable of eliminating bacteria that may remain lodged in dentin after mechanical caries removal. In addition, the use of CHX on acid-etched dentin before adhesive system application delays the resin-dentin interface degradation, maintaining the integrity of the adhesive restorations. Despite these advantages of using CHX in restorative dentistry, when applied on dentin, this chemical agent may diffuse across dentinal tubules to cause toxic effects to the pulp cells. The aim of this study was to evaluate the transdentinal cytotoxic effects caused by diffe...
Source: Cell Research - October 1, 2009 Category: Cytology Authors: Lessa FC, Nogueira I, Huck C, Hebling J, de Souza Costa CA Tags: J Biomed Mater Res B Appl Biomater Source Type: journals

Efficacy of multifaceted interventions in reducing complications of peripherally inserted central catheter in adult oncology patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The results suggest that these interventions implemented in this study may be help in reducing complications of PICC in adult oncology patients. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00520-009-0747-7Authors Geng Tian, The First Affiliated Hospital of Shenzhen University Department of Tumor, Shenzhen Second People’s Hospital 3002 Sungang West Road Shenzhen 518035 People’s Republic of ChinaYan Zhu, The First Affiliated Hospital of Shenzhen University Department of Tumor, Shenzhen Second People’s Hospital 3002 Sungang West Road Shenzhen 518035 People’s Repub...
Source: Supportive Care in Cancer - September 29, 2009 Category: Cancer & Oncology Tags: Supportive Care in Cancer Source Type: journals

Intravascular catheter dressings with chlorhexidine-impregnated sponges reduced infections in the ICU [Treatment]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Evidence-Based Nursing)
Source: Evidence-Based Nursing - September 24, 2009 Category: Nursing Authors: Krau, S. D Tags: Health policy, Immunology (including allergy), Adult intensive care, Trauma Treatment Source Type: journals

The clinical effectiveness and cost-effectiveness of central venous catheters treated with anti-infective agents in preventing bloodstream infections: a systematic review and economic evaluationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: DARE Area: Evidence > Disease Focused Reviews CRD Summary: This well-conducted review assessed the use of central venous catheters treated with anti-infective agents (AI-CVCs) in preventing catheter-related bloodstream infection (CRBSI). The authors concluded that use of AI-CVCs reduced CRBSI rates for durations of five to 12 days and greater than 20 days with femoral or jugular vein insertion. The conclusions were likely to be reliable. [The treating agents used were chlorhexidine and silver sulfadiazine (CHSS), silver impregnation, benzalkonium chloride impregnation, minocycline rifampin, miconazole and rifamp...
Source: NeLM - Infections - September 23, 2009 Category: Infectious Diseases Source Type: organizations

[Treatment] Intravascular catheter dressings with chlorhexidine-impregnated sponges reduced infections in the ICUEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Evidence-Based Nursing)
Source: Evidence-Based Nursing - September 23, 2009 Category: Nursing Authors: Krau, S. D Tags: Health policy, Immunology (including allergy), Adult intensive care, Trauma Treatment Source Type: journals

Antibacterial Efficacy of MTAD Final Rinse and Two Percent Chlorhexidine Gel Medication in Teeth with Apical Periodontitis: A Randomized Double-blinded Clinical TrialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The final rinse with MTAD and medication with CHX did not reduce bacterial counts beyond levels achieved by canal preparation with NaOCl. (Source: Journal of Endodontics)
Source: Journal of Endodontics - September 21, 2009 Category: Dentistry Authors: Gevik Malkhassian, Aldo J. Manzur, Milos Legner, Edward D. Fillery, Sheela Manek, Bettina R. Basrani, Shimon Friedman Tags: CONSORT Randomized Clinical Trials Source Type: journals

Influence of chlorhexidine digluconate concentration and application time on resin–dentin bond strength durabilityEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study evaluated the effects of different concentrations of chlorhexidine digluconate and different application times on the preservation of resin[ndash]dentin bonds formed using two etch-and-rinse adhesives. In experiment 1, after acid etching, the occlusal demineralized dentin was rewetted either with water or with 0.002, 0.02, 0.2, 2, or 4% chlorhexidine for 60 s. In experiment 2, the surfaces were rewetted with water, or with 0.002% or 2% chlorhexidine for 15 or 60 s. After this, both adhesives and composite resin were applied and light-cured. Bonded sticks (0.8 mm2) were tested under tension (0.5 mm min[minus]1) i...
Source: European Journal of Oral Sciences - September 14, 2009 Category: Dentistry Authors: Alessandro D. Loguercio, Rodrigo Stanislawczuk, Luceli G. Polli, Jully A. Costa, Milton D. Michel, Alessandra Reis Tags: Original Articles Source Type: journals

The evaluation of a biodegradable dental chip containing chlorhexidine in chitosan base as a targeted drug delivery in the management of chronic periodontitis in patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
No Abstract (Source: Drug Development Research)
Source: Drug Development Research - September 14, 2009 Category: Drugs & Pharmacology Authors: M.V. Jothi, K.M. Bhat, P.K. Pratibha, Ranjith Kumar, G.S. Bhat Tags: Erratum Source Type: journals

Prevention of Bloodstream Infections by Use of Daily Chlorhexidine Baths for Patients at a Long‐Term Acute Care HospitalEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. Daily chlorhexidine baths appeared to be an effective intervention to reduce rates of CVC‐associated BSI in an LTACH. (Source: Infect Control Hosp Epidemiol Latest Issue)
Source: Infect Control Hosp Epidemiol Latest Issue - September 14, 2009 Category: Epidemiology Tags: article Original Article Source Type: journals

Mutational up-regulation of an RND-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Serratia marescens is an important opportunistic pathogen in hospitals, where quaternary ammonium compounds are often used for disinfection. The aim of this study is to elucidate the effect of a biocide on the emergence of biocide-antibiotic resistant mutants and to characterize the molecular mechanism of biocide resistance in Serratia marcescens. A quaternary ammonium compound-resistant strain, CRes01, was selected by exposing a wild-type strain of S. marcescens to cetylpyridinium chloride. The CRes01 cells exhibited two-to-sixteen fold more resistance to biocides and antibiotics including cetylpyridinium chloride, be...
Source: Antimicrobial Agents and Chemotherapy - September 13, 2009 Category: Microbiology Authors: Maseda H, Hashida Y, Konaka R, Shirai A, Kourai H Tags: Antimicrob Agents Chemother Source Type: journals

Subcutaneous tissue response of isogenic mice to calcium hydroxide-based pastes with chlorhexidine.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, the Calen paste mixed with 0.4% CHX allowed an adequate tissue response, whereas the UltraCal paste mixed with 2% CHX showed unsatisfactory results. PMID: 19738940 [PubMed - in process] (Source: Braz Dent J)
Source: Braz Dent J - September 11, 2009 Category: Dentistry Authors: Silva RA, Assed S, Nelson-Filho P, Silva LA, Consolaro A Tags: Braz Dent J Source Type: journals

Four cases of anaphylaxis to chlorhexidine impregnated central venous catheters: a case cluster or the tip of the iceberg?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: British Journal of Anaesthesia)
Source: British Journal of Anaesthesia - September 10, 2009 Category: Anesthesiology Authors: Jee, R., Nel, L., Gnanakumaran, G., Williams, A., Eren, E. Tags: Correspondence Source Type: journals

Effect of Cinnamon Oil on icaA Expression and Biofilm Formation by Staphylococcus epidermidis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study the effect of cinnamon oil on planktonic and biofilm cultures of clinical S. epidermidis isolates was evaluated. Initially, susceptibility to cinnamon oil in planktonic cultures was compared to commonly-used antimicrobial agents: chlorhexidine, triclosan and gentamicin. The minimal inhibitory concentration (MIC) of cinnamon oil, defined as the lowest concentration able to inhibit visible microbial growth, and the minimal bactericidal concentration (MBC), the lowest concentration required to kill 99,9 % of the bacteria were determined using the microbroth dilution method and plating on agar. A chequerboard ass...
Source: Applied and Environmental Microbiology - September 10, 2009 Category: Microbiology Authors: Nuryastuti T, van der Mei HC, Busscher HJ, Iravati S, Aman AT, Krom BP Tags: Appl Environ Microbiol Source Type: journals

Effectiveness of Oral Rinse with Chlorhexidine in Preventing Nosocomial Respiratory Tract Infections among Intensive Care Unit Patients • Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. Oral application of a 0.12% solution of chlorhexidine does not prevent respiratory tract infections among ICU patients, although it may retard their onset. (Source: Infect Control Hosp Epidemiol Latest Issue)
Source: Infect Control Hosp Epidemiol Latest Issue - September 10, 2009 Category: Epidemiology Tags: article Original Article Source Type: journals

Effects of Preoperative Skin Preparation on Postoperative Wound Infection Rates: A Prospective Study of 3 Skin Preparation Protocols • Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. Skin preparation solution is an important factor in the prevention of surgical‐site infections. Iodophor‐based compounds may be superior to chlorhexidine for this purpose in general surgery patients. (Source: Infect Control Hosp Epidemiol Latest Issue)
Source: Infect Control Hosp Epidemiol Latest Issue - September 10, 2009 Category: Epidemiology Tags: article Original Article Source Type: journals

Effectiveness of Routine Patient Cleansing with Chlorhexidine Gluconate for Infection Prevention in the Medical Intensive Care Unit • Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. In our analysis of real‐world practice, daily bathing of MICU patients with CHG was effective at reducing rates of CVC‐associated BSI and blood culture contamination. Controlled studies are needed to determine whether these beneficial effects extend outside the MICU. (Source: Infect Control Hosp Epidemiol Latest Issue)
Source: Infect Control Hosp Epidemiol Latest Issue - September 10, 2009 Category: Epidemiology Tags: article Original Article Source Type: journals

In vitro activity of chlorhexidine and pentane-1,5-diol and their combination on Candida albicans, Staphylococcus aureus and Propionibacterium acnes.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19734980 [PubMed - in process] (Source: Acta Derm Venereol A...)
Source: Acta Derm Venereol A... - September 9, 2009 Category: Dermatology Authors: Karami N, Alsterholm M, Faergemann J Tags: Acta Derm Venereol Source Type: journals

Surgical Scrub Solution: Chlorhexidine Bathing Is Cheap And Effective Means Of Protecting Patients From SuperbugsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Giving critically ill hospital patients a daily bath with a mild, soapy solution of the same antibacterial agent used by surgeons to "scrub in" before an operation can dramatically cut down, by as much as 73 percent, the number of patients who develop potentially deadly bloodstream infections, according to a new study by patient safety experts. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 8, 2009 Category: Science Source Type: news