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Randomized Double-Blind Assessment of the ONSET and OFFSET of the Antiplatelet Effects of Ticagrelor Versus Clopidogrel in Patients With Stable Coronary Artery Disease. Randomized Double-Blind Assessment of the ONSET and OFFSET of the Antiplatelet Effects of Ticagrelor Versus Clopidogrel in Patients With Stable Cornonary Disease: The ONSET/OFFSET Study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions-Ticagrelor achieved more rapid and greater platelet inhibition than high-loading-dose clopidogrel; this was sustained during the maintenance phase and was faster in offset after drug discontinuation. Clinical Trial Registration Information-URL: http://www.clinicaltrials.gov. Unique identifier: NCT00528411. PMID: 19923168 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 18, 2009 Category: Cardiology Authors: Gurbel PA, Bliden KP, Butler K, Tantry US, Gesheff T, Wei C, Teng R, Antonino MJ, Patil SB, Karunakaran A, Kereiakes DJ, Parris C, Purdy D, Wilson V, Ledley GS, Storey RF Tags: Circulation Source Type: journals

2009 Focused Updates: ACC/AHA Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction (Updating the 2004 Guideline and 2007 Focused Update) and ACC/AHA/SCAI Guidelines on Percutaneous Coronary Intervention (Updating the 2005 Guideline and 2007 Focused Update). A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19923169 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 18, 2009 Category: Cardiology Authors: Kushner FG, Hand M, Smith SC, King SB, Anderson JL, Antman EM, Bailey SR, Bates ER, Blankenship JC, Casey DE, Green LA, Hochman JS, Jacobs AK, Krumholz HM, Morrison DA, Ornato JP, Pearle DL, Peterson ED, Sloan MA, Whitlow PL, Williams DO Tags: Circulation Source Type: journals

Physical Education in Schools Helps Reduce Future Cardiovascular Risk.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19919999 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 17, 2009 Category: Cardiology Authors: Washington RL Tags: Circulation Source Type: journals

Effect of Increased Exercise in School Children on Physical Fitness and Endothelial Progenitor Cells. A Prospective Randomized Trial.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions-Regular physical activity by means of daily school exercise lessons has a significant positive effect on physical fitness (VO2max). Furthermore, the number of circulating progenitor cells can be increased, and there is a positive trend in body mass index-standard deviation score reduction and motor ability improvement. Therefore, we conclude that primary prevention by means of increasing physical activity should start in childhood. Clinical Trial Registration-URL: http://www.clinicaltrials.gov. Identifier: NCT00176371. PMID: 19920000 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 17, 2009 Category: Cardiology Authors: Walther C, Gaede L, Adams V, Gelbrich G, Leichtle A, Erbs S, Sonnabend M, Fikenzer K, Körner A, Kiess W, Bruegel M, Thiery J, Schuler G Tags: Circulation Source Type: journals

The Bypass Angioplasty Revascularization Investigation 2 Diabetes Randomized Trial of Different Treatment Strategies in Type 2 Diabetes Mellitus With Stable Ischemic Heart Disease. Impact of Treatment Strategy on Cardiac Mortality and Myocardial Infarction.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions-In many patients with type 2 diabetes mellitus and stable ischemic coronary disease in whom angina symptoms are controlled, similar to those enrolled in the percutaneous coronary intervention stratum, intensive medical therapy alone should be the first-line strategy. In patients with more extensive coronary disease, similar to those enrolled in the coronary artery bypass grafting stratum, prompt coronary artery bypass grafting, in the absence of contraindications, intensive medical therapy, and an insulin sensitization strategy appears to be a preferred therapeutic strategy to reduce the incidence of MI. Clinic...
Source: Circulation - November 17, 2009 Category: Cardiology Authors: Chaitman BR, Hardison RM, Adler D, Gebhart S, Grogan M, Ocampo S, Sopko G, Ramires JA, Schneider D, Frye RL, Tags: Circulation Source Type: journals

Economic Outcomes of Treatment Strategies for Type 2 Diabetes Mellitus and Coronary Artery Disease in the Bypass Angioplasty Revascularization Investigation 2 Diabetes Trial.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions-Prompt coronary revascularization significantly increases costs among patients with type 2 diabetes mellitus and stable coronary disease. The strategy of medical therapy (with delayed revascularization as needed) appears to be cost-effective compared with the strategy of prompt coronary revascularization among patients identified a priori as suitable for percutaneous coronary intervention. Clinical Trial Registration-URL: http://www.clinicaltrials.gov. Unique Identifier: NCT00006305. PMID: 19920002 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 17, 2009 Category: Cardiology Authors: Hlatky MA, Boothroyd DB, Melsop KA, Kennedy L, Rihal C, Rogers WJ, Venkitachalam L, Brooks MM, Tags: Circulation Source Type: journals

Images in Cardiovascular Medicine. Don't turn your head!Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19917891 [PubMed - in process] (Source: Circulation)
Source: Circulation - November 17, 2009 Category: Cardiology Authors: Helton TJ, Bavry AA Tags: Circulation Source Type: journals

Letter by Baker et al regarding article, "benefits and risks of corticosteroid prophylaxis in adult cardiac surgery: a dose-response meta-analysis".Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19917892 [PubMed - in process] (Source: Circulation)
Source: Circulation - November 17, 2009 Category: Cardiology Authors: Baker WL, White CM, Coleman CI Tags: Circulation Source Type: journals

Letter by Kan et al regarding Article, "randomized trial of warfarin, aspirin, and clopidogrel in patients with chronic heart failure: the Warfarin and Antiplatelet Therapy in Chronic Heart failure (WATCH) trial".Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19917893 [PubMed - in process] (Source: Circulation)
Source: Circulation - November 17, 2009 Category: Cardiology Authors: Kan LP, Chu KM, Lin GM Tags: Circulation Source Type: journals

Mechanisms of immune complex-mediated neutrophil recruitment and tissue injury.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19917895 [PubMed - in process] (Source: Circulation)
Source: Circulation - November 17, 2009 Category: Cardiology Authors: Mayadas TN, Tsokos GC, Tsuboi N Tags: Circulation Source Type: journals

Images in Cardiovascular Medicine. Hypoplasia of the abdominal aorta and hypomelanosis of ito: "pseudo-cauda equina" imaging.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19917896 [PubMed - in process] (Source: Circulation)
Source: Circulation - November 17, 2009 Category: Cardiology Authors: Vivas D, García-Guereta L, Bret M, Rubio D, Burgueros M, Gil M, Gutiérrez-Larraya F Tags: Circulation Source Type: journals

Shouldn't Everyone Have an Implantable Cardioverter-Defibrillator?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19917881 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 16, 2009 Category: Cardiology Authors: Passman R, Kadish A Tags: Circulation Source Type: journals

Endothelial Progenitor Cells Bind and Inhibit Platelet Function and Thrombus Formation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions-Peripheral blood mononuclear cell-derived EPCs bind platelets via CD62P and inhibit platelet activation, aggregation, adhesion to collagen, and thrombus formation, predominantly via upregulation of cyclooxygenase-2 and secretion of prostacyclin. These findings add new insights into the biology of EPCs and define their potential roles in regulating platelet function and thrombosis. PMID: 19917882 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 16, 2009 Category: Cardiology Authors: Abou-Saleh H, Yacoub D, Théorêt JF, Gillis MA, Neagoe PE, Labarthe B, Théroux P, Sirois MG, Tabrizian M, Thorin E, Merhi Y Tags: Circulation Source Type: journals

B-Type Natriuretic Peptides and Cardiovascular Risk. Systematic Review and Meta-Analysis of 40 Prospective Studies.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions-Available prospective studies indicate strong associations between circulating concentration of natriuretic peptides and CVD risk under a range of different circumstances. Further investigation is warranted, particularly in large general population studies, to clarify any predictive utility of these markers and to better control for publication bias. PMID: 19917883 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 16, 2009 Category: Cardiology Authors: Di Angelantonio E, Chowdhury R, Sarwar N, Ray KK, Gobin R, Saleheen D, Thompson A, Gudnason V, Sattar N, Danesh J Tags: Circulation Source Type: journals

High Residual Platelet Reactivity After Clopidogrel Loading and Long-Term Clinical Outcome After Drug-Eluting Stenting for Unprotected Left Main Coronary Disease.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions-HRPR after 600-mg clopidogrel loading is a strong marker of increased risk of cardiac death and DES thrombosis in patients receiving DES stenting for ULMD. Routine assessment of in vitro residual platelet reactivity after clopidogrel loading in patients with ULMD potentially suitable for DES-supported percutaneous coronary intervention should be considered to guide patient care decisions. PMID: 19917884 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 16, 2009 Category: Cardiology Authors: Migliorini A, Valenti R, Marcucci R, Parodi G, Giuliani G, Buonamici P, Cerisano G, Carrabba N, Gensini GF, Abbate R, Antoniucci D Tags: Circulation Source Type: journals

Validation of Magnetic Resonance Myocardial Perfusion Imaging With Fractional Flow Reserve for the Detection of Significant Coronary Heart Disease.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion-MRMPI can detect functionally significant coronary heart disease with excellent sensitivity, specificity, and positive and negative predictive values compared with FFR. PMID: 19917885 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 16, 2009 Category: Cardiology Authors: Watkins S, McGeoch R, Lyne J, Steedman T, Good R, McLaughlin MJ, Cunningham T, Bezlyak V, Ford I, Dargie HJ, Oldroyd KG Tags: Circulation Source Type: journals

Priming With Angiopoietin-1 Augments the Vasculogenic Potential of the Peripheral Blood Stem Cells Mobilized With Granulocyte Colony-Stimulating Factor Through a Novel Tie2/Ets-1 Pathway.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions-The short-term priming with COMP-Ang1 may be a feasible and promising option to activate (mob)PBSCs by enhancing differentiation and adhesiveness and to improve the efficacy of cell therapy for ischemic diseases. PMID: 19917886 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 16, 2009 Category: Cardiology Authors: Kim MS, Lee CS, Hur J, Cho HJ, Jun SI, Kim TY, Lee SW, Suh JW, Park KW, Lee HY, Kang HJ, Lee DS, Koh GY, Nakagami H, Morishita R, Park YB, Kim HS Tags: Circulation Source Type: journals

Impact of Implantable Cardioverter-Defibrillator, Amiodarone, and Placebo on the Mode of Death in Stable Patients With Heart Failure. Analysis From the Sudden Cardiac Death in Heart Failure Trial.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions-ICD therapy reduced cardiac mortality and sudden death presumed to be ventricular tachyarrhythmic in SCD-HeFT and had no effect on heart failure mortality. Amiodarone had no effect on all-cause mortality or its cause-specific components. Clinical Trial Registration Information-URL: http://www.clinicaltrials.gov. Unique identifier: NCT00000609. PMID: 19917887 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 16, 2009 Category: Cardiology Authors: Packer DL, Prutkin JM, Hellkamp AS, Mitchell LB, Bernstein RC, Wood F, Boehmer JP, Carlson MD, Frantz RP, McNulty SE, Rogers JG, Anderson J, Johnson GW, Walsh MN, Poole JE, Mark DB, Lee KL, Bardy GH Tags: Circulation Source Type: journals

Effects of Statin Therapy According to Plasma High-Sensitivity C-Reactive Protein Concentration in the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA). A Retrospective Analysis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion-In this retrospective hypothesis-generating study, we found a significant interaction between hs-CRP and the effect of rosuvastatin for most end points whereby rosuvastatin treatment was associated with better outcomes in patients with hs-CRP >/=2.0 mg/L. Clinical Trial Registration Information-URL: http://www.clinicaltrials.gov. Unique identifier: NCT00206310. PMID: 19917888 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 16, 2009 Category: Cardiology Authors: McMurray JJ, Kjekshus J, Gullestad L, Dunselman P, Hjalmarson A, Wedel H, Lindberg M, Waagstein F, Grande P, Hradec J, Kamensky G, Korewicki J, Kuusi T, Mach F, Ranjith N, Wikstrand J, Tags: Circulation Source Type: journals

Vascular Endothelial-Specific Dimethylarginine Dimethylaminohydrolase-1-Deficient Mice Reveal That Vascular Endothelium Plays an Important Role in Removing Asymmetric Dimethylarginine.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions-Our study demonstrates that DDAH1 is highly expressed in vascular endothelium and that endothelial DDAH1 plays an important role in regulating blood pressure. In the context that asymmetric methylarginines are broadly produced by many type of cells, the strong DDAH1 expression in vascular endothelium demonstrates for the first time that vascular endothelium can be an important site to actively dispose of toxic biochemical molecules produced by other types of cells. PMID: 19917889 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 16, 2009 Category: Cardiology Authors: Hu X, Xu X, Zhu G, Atzler D, Kimoto M, Chen J, Schwedhelm E, Lüneburg N, Böger RH, Zhang P, Chen Y Tags: Circulation Source Type: journals

Prognostic Implications of Myocardial Perfusion Single-Photon Emission Computed Tomography in the Elderly.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions-Stress MPS effectively stratifies CD risk in elderly patients and may identify optimal post-MPS therapy. CD rates after normal MPS are low in all subsets in relative terms compared with the age-matched US population. PMID: 19917890 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 16, 2009 Category: Cardiology Authors: Hachamovitch R, Kang X, Amanullah AM, Abidov A, Hayes SW, Friedman JD, Cohen I, Thomson LE, Germano G, Berman DS Tags: Circulation Source Type: journals

Images in cardiovascular medicine. Adventitial fibromuscular dysplasia of the renal artery: management challenges of nonatherosclerotic renal artery stenosis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19901199 [PubMed - in process] (Source: Circulation)
Source: Circulation - November 10, 2009 Category: Cardiology Authors: Weiner RB, Kiernan TJ, Yan BP, Rosenfield K, Jaff MR Tags: Circulation Source Type: journals

Letter by Brown and Pretorius regarding article, "effect of sulfaphenazole on tissue plasminogen activator release in normotensive subjects and hypertensive patients".Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19901200 [PubMed - in process] (Source: Circulation)
Source: Circulation - November 10, 2009 Category: Cardiology Authors: Brown NJ, Pretorius M Tags: Circulation Source Type: journals

Left atrial appendage occlusion eliminates the need for warfarin.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19901202 [PubMed - in process] (Source: Circulation)
Source: Circulation - November 10, 2009 Category: Cardiology Authors: Holmes DR, Schwartz RS Tags: Circulation Source Type: journals

Left atrial appendage occlusion does not eliminate the need for warfarin.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19901203 [PubMed - in process] (Source: Circulation)
Source: Circulation - November 10, 2009 Category: Cardiology Authors: Whitlock RP, Healey JS, Connolly SJ Tags: Circulation Source Type: journals

Images in cardiovascular medicine. Cardiac CT assessment of prosthetic aortic valve dysfunction secondary to acute thrombosis and response to thrombolysis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19901204 [PubMed - in process] (Source: Circulation)
Source: Circulation - November 10, 2009 Category: Cardiology Authors: Chan J, Marwan M, Schepis T, Ropers D, Du L, Achenbach S Tags: Circulation Source Type: journals

Is the Optimal Management of Acute Type A Aortic Intramural Hematoma Evolving?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19901184 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 9, 2009 Category: Cardiology Authors: Evangelista A, Eagle KA Tags: Circulation Source Type: journals

The Ankle-Brachial Index as a Biomarker of Cardiovascular Risk. It's Not Just About the Legs.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19901185 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 9, 2009 Category: Cardiology Authors: Perlstein TS, Creager MA Tags: Circulation Source Type: journals

C-Reactive Protein and Coronary Disease. Is There a Causal Link?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19901186 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 9, 2009 Category: Cardiology Authors: Danesh J, Pepys MB Tags: Circulation Source Type: journals

Enhancement of Myocardial Regeneration Through Genetic Engineering of Cardiac Progenitor Cells Expressing Pim-1 Kinase.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions-Myocardial repair is significantly enhanced by genetic engineering of CPCs with Pim-1 kinase. Ex vivo gene delivery to enhance cellular survival, proliferation, and regeneration may overcome current limitations of stem cell-based therapeutic approaches. PMID: 19901187 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 9, 2009 Category: Cardiology Authors: Fischer KM, Cottage CT, Wu W, Din S, Gude NA, Avitabile D, Quijada P, Collins BL, Fransioli J, Sussman MA Tags: Circulation Source Type: journals

Outcomes of Patients With Acute Type A Aortic Intramural Hematoma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions-The clinical outcome of IMH patients receiving treatment by our policy was comparable to that of surgically treated AD patients. However, adverse clinical events were not uncommon with medical treatment alone, and initial aorta diameter and hematoma thickness may identify patients who might benefit from urgent surgery. PMID: 19901188 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 9, 2009 Category: Cardiology Authors: Song JK, Yim JH, Ahn JM, Kim DH, Kang JW, Lee TY, Song JM, Choo SJ, Kang DH, Chung CH, Lee JW, Lim TH Tags: Circulation Source Type: journals

A Common Variant at 9p21 Is Associated With Sudden and Arrhythmic Cardiac Death.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions-The major allele of a single-nucleotide polymorphism previously associated with increased risk of coronary artery disease events is associated with increased risk of SCD in individuals of European ancestry. Study of the mechanism underlying this association may improve our understanding of lethal cardiovascular disease. PMID: 19901189 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 9, 2009 Category: Cardiology Authors: Newton-Cheh C, Cook NR, Vandenburgh M, Rimm EB, Ridker PM, Albert CM Tags: Circulation Source Type: journals

Human C-Reactive Protein Does Not Promote Atherosclerosis in Transgenic Rabbits.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions-Neither high nor low plasma concentrations of hCRP affected aortic or coronary atherosclerosis lesion formation in hCRP-Tg rabbits. PMID: 19901190 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 9, 2009 Category: Cardiology Authors: Koike T, Kitajima S, Yu Y, Nishijima K, Zhang J, Ozaki Y, Morimoto M, Watanabe T, Bhakdi S, Asada Y, Chen YE, Fan J Tags: Circulation Source Type: journals

Reconstituted High-Density Lipoprotein Attenuates Platelet Function in Individuals With Type 2 Diabetes Mellitus by Promoting Cholesterol Efflux.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion-These findings suggest that rHDL therapy is highly effective at inhibiting the heightened reactivity of diabetic platelets, partly through reducing the cholesterol content of platelet membranes. These properties, combined with the known short-term beneficial effects of rHDL on atherosclerotic lesions, suggest that rHDL infusions may be an effective approach to reduce atherothrombotic complications in diabetic individuals. Clinical Trial Registration Information-URL: http://www.clinicaltrials.gov. Unique identifier: NCT00395148. PMID: 19901191 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 9, 2009 Category: Cardiology Authors: Calkin AC, Drew BG, Ono A, Duffy SJ, Gordon MV, Schoenwaelder SM, Sviridov D, Cooper ME, Kingwell BA, Jackson SP Tags: Circulation Source Type: journals

Mortality and Vascular Morbidity in Older Adults With Asymptomatic Versus Symptomatic Peripheral Artery Disease.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions-Asymptomatic PAD diagnosed through routine screening in the offices of primary care physicians carries a high mortality and/or vascular event risk. Notably, the risk of mortality was similar in symptomatic and asymptomatic patients with PAD and was significantly higher than in those without PAD. In the primary care setting, the diagnosis of PAD has important prognostic value. PMID: 19901192 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 9, 2009 Category: Cardiology Authors: Diehm C, Allenberg JR, Pittrow D, Mahn M, Tepohl G, Haberl RL, Darius H, Burghaus I, Trampisch HJ, Tags: Circulation Source Type: journals

Prognostic Significance of Delayed-Enhancement Magnetic Resonance Imaging. Survival of 857 Patients With and Without Left Ventricular Dysfunction.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion-The degree of DE detected by DE-MRI appears to strongly predict all-cause mortality or cardiac transplantation after adjustment for traditional, well-known prognosticators. PMID: 19901193 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 9, 2009 Category: Cardiology Authors: Cheong BY, Muthupillai R, Wilson JM, Sung A, Huber S, Amin S, Elayda MA, Lee VV, Flamm SD Tags: Circulation Source Type: journals

Heart Rate Predicts Outcomes in an Implantable Cardioverter-Defibrillator Population.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions-In this ICD population, the mean intrinsic HR was strongly associated with outcomes. Clinical Trial Registration-http://www.clinicaltrials.gov. Identifier: NCT00148967. PMID: 19901194 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 9, 2009 Category: Cardiology Authors: Ahmadi-Kashani M, Kessler DJ, Day J, Bunch TJ, Stolen KQ, Brown S, Sbaity S, Olshansky B, Tags: Circulation Source Type: journals

Images in cardiovascular medicine. Huge prosthetic mitral valve thrombosis in a pregnant woman.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19884477 [PubMed - in process] (Source: Circulation)
Source: Circulation - November 3, 2009 Category: Cardiology Authors: Ozkan M, Biteker M, Duran NE, Yildiz M Tags: Circulation Source Type: journals

Letter by Barrios et al regarding article, "Impact of proteinuria and glomerular filtration rate on risk of thromboembolism in atrial fibrillation: the Anticoagulation and Risk Factors in Atrial Fibrillation (ATRIA) study".Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19884478 [PubMed - in process] (Source: Circulation)
Source: Circulation - November 3, 2009 Category: Cardiology Authors: Barrios V, Escobar C, Echarri R Tags: Circulation Source Type: journals

Letter by Hamilton-Craig et al regarding article, "Posttraumatic cardiac contrecoup: in vivo evidence by cardiac magnetic resonance imaging".Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19884479 [PubMed - in process] (Source: Circulation)
Source: Circulation - November 3, 2009 Category: Cardiology Authors: Hamilton-Craig C, Layland J, Platts D, Hansen M, Slaughter R, Fraser J Tags: Circulation Source Type: journals

Coronary microembolization: from bedside to bench and back to bedside.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Coronary microembolization from the erosion or rupture of a vulnerable atherosclerotic plaque occurs spontaneously in acute coronary syndromes and iatrogenically during percutaneous coronary interventions. Typical consequences of coronary microembolization are microinfarcts with an inflammatory response, contractile dysfunction, and reduced coronary reserve. Apart from transient elevations of creatine kinase and troponin, microemboli can be visualized by intracoronary Doppler and the resulting microinfarcts by late-enhancement nuclear magnetic resonance. Statins, antiplatelet agents, and coronary vasodilators protect a...
Source: Circulation - November 3, 2009 Category: Cardiology Authors: Heusch G, Kleinbongard P, Böse D, Levkau B, Haude M, Schulz R, Erbel R Tags: Circulation Source Type: journals

Catheter-based closure of the patent foramen ovale.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19884482 [PubMed - in process] (Source: Circulation)
Source: Circulation - November 3, 2009 Category: Cardiology Authors: Meier B Tags: Circulation Source Type: journals

Images in cardiovascular medicine. Subclavian artery occlusion masquerading as painful breast plaque.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19884483 [PubMed - in process] (Source: Circulation)
Source: Circulation - November 3, 2009 Category: Cardiology Authors: Wetter DA, McEvoy MT, Bashir R, Mathew V Tags: Circulation Source Type: journals

History and Current Impact of Cardiac Magnetic Resonance Imaging on the Management of Iron Overload.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19884464 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 2, 2009 Category: Cardiology Authors: Wood JC Tags: Circulation Source Type: journals

Secondary Prevention, the Interventional Way. Prophylactic Drug-Eluting Stents for Nonobstructive Saphenous Vein Graft Disease.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19884465 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 2, 2009 Category: Cardiology Authors: Parikh SA, Costa MA Tags: Circulation Source Type: journals

Chronic Pulmonary Artery Pressure Elevation Is Insufficient to Explain Right Heart Failure.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion-These data brought into question the commonly held concept that RV failure associated with pulmonary hypertension is due strictly to the increased RV afterload. PMID: 19884466 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 2, 2009 Category: Cardiology Authors: Bogaard HJ, Natarajan R, Henderson SC, Long CS, Kraskauskas D, Smithson L, Ockaili R, McCord JM, Voelkel NF Tags: Circulation Source Type: journals

C-Reactive Protein and the Risk of Stent Thrombosis and Cardiovascular Events After Drug-Eluting Stent Implantation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions-Elevated CRP levels were significantly associated with increased risks of stent thrombosis, death, and MI in patients receiving drug-eluting stents, suggesting the usefulness of inflammatory risk assessment with CRP. Given the relatively infrequent occurrence of stent thrombosis, death, and MI, larger studies with longer-term follow-up are required to confirm the novel relationship. PMID: 19884467 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 2, 2009 Category: Cardiology Authors: Park DW, Yun SC, Lee JY, Kim WJ, Kang SJ, Lee SW, Kim YH, Lee CW, Kim JJ, Park SW, Park SJ Tags: Circulation Source Type: journals

Comparison of Plaque Sealing With Paclitaxel-Eluting Stents Versus Medical Therapy for the Treatment of Moderate Nonsignificant Saphenous Vein Graft Lesions. The Moderate VEin Graft LEsion Stenting With the Taxus Stent and Intravascular Ultrasound (VELETI) Pilot Trial.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions-Stenting moderate nonsignificant lesions in old SVGs with PES was associated with a lower rate of SVG disease progression and a trend toward a lower incidence of major adverse cardiac events at 1-year follow-up compared with medical treatment alone, despite very low low-density lipoprotein cholesterol values. This pilot study supports further investigation into the role of plaque sealing in SVGs. Clinical Trial Registration-URL: http://www.clinicaltrials.gov. Unique identifier: NCT002289835. PMID: 19884468 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 2, 2009 Category: Cardiology Authors: Rodés-Cabau J, Bertrand OF, Larose E, Déry JP, Rinfret S, Bagur R, Proulx G, Nguyen CM, Côté M, Landcop MC, Boudreault JR, Rouleau J, Roy L, Gleeton O, Barbeau G, Noël B, Courtis J, Dagenais GR, Després JP, Delarochelliè Tags: Circulation Source Type: journals

Major Bleeding, Mortality, and Efficacy of Fondaparinux in Venous Thromboembolism Prevention Trials.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions-Major bleeding in hospitalized surgical and medical patients participating in venous thromboembolism prevention trials is a strong predictor of mortality. PMID: 19884469 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 2, 2009 Category: Cardiology Authors: Eikelboom JW, Quinlan DJ, O'Donnell M Tags: Circulation Source Type: journals

Oral Anti-CD3 Antibody Treatment Induces Regulatory T Cells and Inhibits the Development of Atherosclerosis in Mice.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions-Our findings indicate the atheroprotective role of oral anti-CD3 antibody treatment in mice via induction of a regulatory T-cell response. These findings suggest that oral immune modulation may represent an attractive therapeutic approach to atherosclerosis. PMID: 19884470 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - November 2, 2009 Category: Cardiology Authors: Sasaki N, Yamashita T, Takeda M, Shinohara M, Nakajima K, Tawa H, Usui T, Hirata KI Tags: Circulation Source Type: journals