Clinical, Cosmetic and Investigational Dermatology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

A Sporadic Family of Lipoid Proteinosis with Novel < em > ECM1 < /em > Gene Mutations
Clin Cosmet Investig Dermatol. 2024 Apr 18;17:885-889. doi: 10.2147/CCID.S452127. eCollection 2024.ABSTRACTLipoid proteinosis (LP) is an uncommon, autosomal recessive genetic disorder. Multigene panel testing was conducted to confirm the diagnosis of a sporadic family with suspected LP. In the proband, we identified two mutations of ECMI and provided genetic evidence for informed genetic counselling.PMID:38651074 | PMC:PMC11034508 | DOI:10.2147/CCID.S452127 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - April 23, 2024 Category: Dermatology Authors: Yu-Ling Liu Zeng-Yun-Ou Zhang Xiao-Mei Chen Source Type: research

Assessment of the Effect of < em > Rehmannia glutinosa < /em > Leaf Extract in Maintaining Skin Health: A Proof-of-Concept, Double-Blind, Randomized, Placebo-Controlled Clinical Trial
CONCLUSION: RGLE supplementation at a dose of 100 mg/day has provided a clinically relevant decrease in acne severity and improved the skin hydration and quality of life of the participants with acne after 56 days of dose administration.PMID:38651075 | PMC:PMC11034513 | DOI:10.2147/CCID.S448928 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - April 23, 2024 Category: Dermatology Authors: Shalini Srivastava Shu Fen Huang Manjiri S Jagtap Source Type: research

Hidradenitis Suppurativa Online Documents Readability: An Analysis Including 23 European Languages
CONCLUSION: Despite the coverage of HS on the Internet, its complexity made it hard to comprehend. Dermatologist should ensure readable, barrier-free online educational materials. With adequate Google promotion, these would be beneficial for both physicians and patients.PMID:38644990 | PMC:PMC11032155 | DOI:10.2147/CCID.S463861 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - April 22, 2024 Category: Dermatology Authors: Tomasz Skrzypczak Anna Skrzypczak Jacek C Szepietowski Source Type: research

Very Early Pulsed Dye Laser Intervention for Optimal Cosmetic Outcome in Post-Thyroidectomy Scars
CONCLUSION: Early intervention using a pulsed dye laser within 3 weeks of thyroidectomy can substantially inhibit pathological scar development, providing physicians with a guide for optimal treatment commencement.PMID:38644991 | PMC:PMC11032680 | DOI:10.2147/CCID.S444885 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - April 22, 2024 Category: Dermatology Authors: Yul Hee Kim Han-Seul Kim Hyeung Kyoo Kim Soo Young Kim Jeonghun Lee You Chan Kim Young Joon Park Source Type: research

Mimicking Rosacea? Jessner's Lymphocytic Infiltration of the Skin: A Case Report
We report a case of rash in a 35-year-old female presenting with erythematous papules and infiltrative plaques on the nose and upper jaw resembling rosacea. The patient had been experiencing these symptoms for one year. A pathological biopsy revealed an inflammatory infiltrate consisting of dense perivascular lymphocytes surrounding hair follicles and sweat glands in the dermis. Immunohistochemistry demonstrated a predominance of CD4+ T cells compared to CD8+ T cells. Based on the clinical manifestations, histopathology, and immunohistochemistry, the patient was diagnosed with Jessner's Lymphocytic infiltration of the skin...
Source: Clinical, Cosmetic and Investigational Dermatology - April 18, 2024 Category: Dermatology Authors: Lingjia Li Yulan Wang Hua Gu Source Type: research

A Case of Persistent Pityriasis Rosea Successfully Treated by a Short Course of Therapy with Abrocitinib
We report a 25-year-old female patient with a six-month history of red scaly rashes on the trunk and proximal limbs, accompanied by severe pruritus that has been remained ineffective conventional treatments. She was diagnosed as persistent pityriasis rosea. As abrocitinib has been proved to be effective for many inflammatory diseases, therefore in this case, we tried abrocitinib for the patient, and a good result had been achieved.PMID:38628635 | PMC:PMC11020286 | DOI:10.2147/CCID.S455060 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - April 17, 2024 Category: Dermatology Authors: Hao Wu Qing-Jie Ji Yu-Yang Xu Jian-Wei Zhu Source Type: research

A Case of Verruciform Xanthoma of Labia in a Child
CONCLUSION: Surgical intervention proved successful in achieving favorable outcomes for the patient.PMID:38616885 | PMC:PMC11011726 | DOI:10.2147/CCID.S432399 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - April 15, 2024 Category: Dermatology Authors: Meihua He Mingqiang Liu Xiaohua Tao Source Type: research

The Role of Interleukin 23/17 Axis in Psoriasis Management: A Comprehensive Review of Clinical Trials
Clin Cosmet Investig Dermatol. 2024 Apr 10;17:829-842. doi: 10.2147/CCID.S462797. eCollection 2024.ABSTRACTPsoriasis pathogenesis is influenced by genetic factors and characterized by a complex interplay between genetic predisposition and various environmental triggers. These triggers set off metabolic processes involving inflammation, cell signaling, immune response dysregulation, and antigen presentation. Several types of innate and adaptive immune cells are involved in psoriasis. Among the cytokine cascade which leads to psoriasis development, the interleukin (IL)-23/Th17 axis, especially IL-17 production, emerges as cr...
Source: Clinical, Cosmetic and Investigational Dermatology - April 15, 2024 Category: Dermatology Authors: Luca Potestio Fabrizio Martora Giuseppe Lauletta Ylenia Vallone Teresa Battista Matteo Megna Source Type: research

Trichoscopic Features of Scalp Discoid Lupus Erythematosus versus Lichen Planopilaris: A Systematic Review
CONCLUSION: This article provides a comprehensive review of the literature and delineates the trichoscopic differences and peculiarities of scalp DLE and LPP, including the correlation of dermoscopic features with histopathological findings.PMID:38616887 | PMC:PMC11015838 | DOI:10.2147/CCID.S460742 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - April 15, 2024 Category: Dermatology Authors: Shreya K Gowda Enzo Errichetti Vishal Thakur Maitreyee Panda Siddhartha Dash Akash Agarwal Madhusmita Sethy Pavithra Ayyanar Biswanath Behera Source Type: research

Salvianolic Acid B Reduces Oxidative Stress to Promote Hair-Growth in Mice, Human Hair Follicles and Dermal Papilla Cells
CONCLUSION: The study indicates that SAB promotes hDPC proliferation and offers protection against oxidative stress, highlighting its potential as a therapeutic agent for enhancing hair growth and treating hair loss.PMID:38616888 | PMC:PMC11011644 | DOI:10.2147/CCID.S454844 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - April 15, 2024 Category: Dermatology Authors: Traidit Thianthanyakij Yinghui Zhou Mengyi Wu Yuting Zhang Jui-Ming Lin Yan Huang Yuou Sha Jiayi Wang Sirapath Peter Kong Jinran Lin Qingmei Liu Wenyu Wu Source Type: research