New solutions to old problems: A practical approach to identify samples with intravenous fluid contamination in clinical laboratories
CONCLUSIONS: The proposed algorithm identified true contamination with low false flagging rates in tertiary care urban hospital laboratories. Retrospective and prospective analysis suggest the algorithm is suitable for implementation in clinical laboratories to identify samples with possible IV fluid contamination for further investigation.PMID:38615787 | DOI:10.1016/j.clinbiochem.2024.110763 (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - April 14, 2024 Category: Biochemistry Authors: Ashley Newbigging Natalie Landry Miranda Brun Dustin Proctor Michelle Parker Carmen Zimmer Laurel Thorlacius Joshua E Raizman Albert K Y Tsui Source Type: research

Salivary testosterone changes during oral glucose tolerance tests in overweight and obese men - postprandial or circadian variation?
CONCLUSIONS: SalT decreased postprandially. A concomitant decrease in serum cortisol, prolactin and TSH reflecting diurnal variation offers an alternative explanation for the decrease in SalT independent of food consumption. Further studies are required to determine whether morning temporal changes in SalT are related to food consumption or circadian rhythm or both.PMID:38591370 | DOI:10.1177/00045632241249087 (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - April 9, 2024 Category: Biochemistry Authors: Jonathan Fenn Henry Gill Lauren Starbrook Loretta Theresa Ford Hayley Sharrod-Cole Tejas Kalaria Clare Ford Rousseau Gama Source Type: research

Improvement of point of care testing (POCT) device for accurate whole blood glucose measurement in early neonates
CONCLUSION: The study showed that the point-of-care testing device could be improved to allow for accurate whole-blood glucose measurements in the early neonatal period.PMID:38591468 | DOI:10.1177/00045632241249034 (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - April 9, 2024 Category: Biochemistry Authors: Kosuke Koyano Makoto Arioka Yasuhiro Nakao Aya Morimoto Masashiro Sugino Hirosuke Morita Shinji Nakamura Sonoko Kondo Yukihiko Konishi Saneyuki Yasuda Takashi Kusaka Source Type: research

Salivary testosterone changes during oral glucose tolerance tests in overweight and obese men - postprandial or circadian variation?
CONCLUSIONS: SalT decreased postprandially. A concomitant decrease in serum cortisol, prolactin and TSH reflecting diurnal variation offers an alternative explanation for the decrease in SalT independent of food consumption. Further studies are required to determine whether morning temporal changes in SalT are related to food consumption or circadian rhythm or both.PMID:38591370 | DOI:10.1177/00045632241249087 (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - April 9, 2024 Category: Biochemistry Authors: Jonathan Fenn Henry Gill Lauren Starbrook Loretta Theresa Ford Hayley Sharrod-Cole Tejas Kalaria Clare Ford Rousseau Gama Source Type: research

Improvement of point of care testing (POCT) device for accurate whole blood glucose measurement in early neonates
CONCLUSION: The study showed that the point-of-care testing device could be improved to allow for accurate whole-blood glucose measurements in the early neonatal period.PMID:38591468 | DOI:10.1177/00045632241249034 (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - April 9, 2024 Category: Biochemistry Authors: Kosuke Koyano Makoto Arioka Yasuhiro Nakao Aya Morimoto Masashiro Sugino Hirosuke Morita Shinji Nakamura Sonoko Kondo Yukihiko Konishi Saneyuki Yasuda Takashi Kusaka Source Type: research

Salivary testosterone changes during oral glucose tolerance tests in overweight and obese men - postprandial or circadian variation?
CONCLUSIONS: SalT decreased postprandially. A concomitant decrease in serum cortisol, prolactin and TSH reflecting diurnal variation offers an alternative explanation for the decrease in SalT independent of food consumption. Further studies are required to determine whether morning temporal changes in SalT are related to food consumption or circadian rhythm or both.PMID:38591370 | DOI:10.1177/00045632241249087 (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - April 9, 2024 Category: Biochemistry Authors: Jonathan Fenn Henry Gill Lauren Starbrook Loretta Theresa Ford Hayley Sharrod-Cole Tejas Kalaria Clare Ford Rousseau Gama Source Type: research

Improvement of point of care testing (POCT) device for accurate whole blood glucose measurement in early neonates
CONCLUSION: The study showed that the point-of-care testing device could be improved to allow for accurate whole-blood glucose measurements in the early neonatal period.PMID:38591468 | DOI:10.1177/00045632241249034 (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - April 9, 2024 Category: Biochemistry Authors: Kosuke Koyano Makoto Arioka Yasuhiro Nakao Aya Morimoto Masashiro Sugino Hirosuke Morita Shinji Nakamura Sonoko Kondo Yukihiko Konishi Saneyuki Yasuda Takashi Kusaka Source Type: research

Salivary testosterone changes during oral glucose tolerance tests in overweight and obese men - postprandial or circadian variation?
CONCLUSIONS: SalT decreased postprandially. A concomitant decrease in serum cortisol, prolactin and TSH reflecting diurnal variation offers an alternative explanation for the decrease in SalT independent of food consumption. Further studies are required to determine whether morning temporal changes in SalT are related to food consumption or circadian rhythm or both.PMID:38591370 | DOI:10.1177/00045632241249087 (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - April 9, 2024 Category: Biochemistry Authors: Jonathan Fenn Henry Gill Lauren Starbrook Loretta Theresa Ford Hayley Sharrod-Cole Tejas Kalaria Clare Ford Rousseau Gama Source Type: research

Improvement of point of care testing (POCT) device for accurate whole blood glucose measurement in early neonates
CONCLUSION: The study showed that the point-of-care testing device could be improved to allow for accurate whole-blood glucose measurements in the early neonatal period.PMID:38591468 | DOI:10.1177/00045632241249034 (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - April 9, 2024 Category: Biochemistry Authors: Kosuke Koyano Makoto Arioka Yasuhiro Nakao Aya Morimoto Masashiro Sugino Hirosuke Morita Shinji Nakamura Sonoko Kondo Yukihiko Konishi Saneyuki Yasuda Takashi Kusaka Source Type: research

Salivary testosterone changes during oral glucose tolerance tests in overweight and obese men - postprandial or circadian variation?
CONCLUSIONS: SalT decreased postprandially. A concomitant decrease in serum cortisol, prolactin and TSH reflecting diurnal variation offers an alternative explanation for the decrease in SalT independent of food consumption. Further studies are required to determine whether morning temporal changes in SalT are related to food consumption or circadian rhythm or both.PMID:38591370 | DOI:10.1177/00045632241249087 (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - April 9, 2024 Category: Biochemistry Authors: Jonathan Fenn Henry Gill Lauren Starbrook Loretta Theresa Ford Hayley Sharrod-Cole Tejas Kalaria Clare Ford Rousseau Gama Source Type: research

Improvement of point of care testing (POCT) device for accurate whole blood glucose measurement in early neonates
CONCLUSION: The study showed that the point-of-care testing device could be improved to allow for accurate whole-blood glucose measurements in the early neonatal period.PMID:38591468 | DOI:10.1177/00045632241249034 (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - April 9, 2024 Category: Biochemistry Authors: Kosuke Koyano Makoto Arioka Yasuhiro Nakao Aya Morimoto Masashiro Sugino Hirosuke Morita Shinji Nakamura Sonoko Kondo Yukihiko Konishi Saneyuki Yasuda Takashi Kusaka Source Type: research

Prostate Health Index (PHI) as a triage tool for reducing unnecessary magnetic resonance imaging (MRI) in patients at risk of prostate cancer
CONCLUSION: PHI could represent a reliable noninvasive tool for selecting patients to undergo mpMRI.PMID:38583655 | DOI:10.1016/j.clinbiochem.2024.110759 (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - April 7, 2024 Category: Biochemistry Authors: Luisa Agnello Matteo Vidali Giuseppe Salvaggio Francesco Agnello Bruna Lo Sasso Caterina Maria Gambino Marcello Ciaccio Source Type: research

Prostate Health Index (PHI) as a triage tool for reducing unnecessary magnetic resonance imaging (MRI) in patients at risk of prostate cancer
CONCLUSION: PHI could represent a reliable noninvasive tool for selecting patients to undergo mpMRI.PMID:38583655 | DOI:10.1016/j.clinbiochem.2024.110759 (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - April 7, 2024 Category: Biochemistry Authors: Luisa Agnello Matteo Vidali Giuseppe Salvaggio Francesco Agnello Bruna Lo Sasso Caterina Maria Gambino Marcello Ciaccio Source Type: research

Age- and sex-specific 99th percentile upper reference limits for high-sensitivity cardiac troponin T in Chinese older people: Real-world data mining
CONCLUSION: This study establishes age- and sex-specific 99th percentile URLs for hs-cTnT in Chinese older individuals, thereby enhancing the accuracy of clinical assessments.PMID:38582381 | DOI:10.1016/j.clinbiochem.2024.110762 (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - April 6, 2024 Category: Biochemistry Authors: Qian Zhang Huiyi Chen Meng Wang Huiying Lai Wensong Liu Lijuan Wang Jiaqi Zhang Chuanbao Li Weiyan Zhou Source Type: research

Age- and sex-specific 99th percentile upper reference limits for high-sensitivity cardiac troponin T in Chinese older people: Real-world data mining
CONCLUSION: This study establishes age- and sex-specific 99th percentile URLs for hs-cTnT in Chinese older individuals, thereby enhancing the accuracy of clinical assessments.PMID:38582381 | DOI:10.1016/j.clinbiochem.2024.110762 (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - April 6, 2024 Category: Biochemistry Authors: Qian Zhang Huiyi Chen Meng Wang Huiying Lai Wensong Liu Lijuan Wang Jiaqi Zhang Chuanbao Li Weiyan Zhou Source Type: research