Can subunit ‐specific phenotypes guide surveillance imaging decisions in asymptomatic SDH mutation carriers?
ConclusionsUsing this data, we suggest surveillance screening of asymptomatic carriers can be tailored to the underlyingSDH subunit and review possible surveillance programmes. (Source: Clinical Endocrinology)
Source: Clinical Endocrinology - November 28, 2018 Category: Endocrinology Authors: Nicola Tufton, Anju Sahdev, William M. Drake, Scott A. Akker Tags: REVIEW ARTICLE Source Type: research

In Response to Fang et al ’s Comment on “diagnostic accuracy of the McGill thyroid nodule score in pediatric patients”
Clinical Endocrinology, EarlyView. (Source: Clinical Endocrinology)
Source: Clinical Endocrinology - November 26, 2018 Category: Endocrinology Authors: Ana Creo, Fares Alahdab, Alaa Al Nofal, Kristen Thomas, Amy Kolbe, Siobhan Pittock Tags: LETTER TO THE EDITOR Source Type: research

Higher circulating androgens and higher physical activity levels are associated with less central adiposity and lower risk of cardiovascular death in older men
ConclusionHigher circulating androgens and higher PA were associated with less central adiposity at baseline and fewer CVD deaths during follow ‐up. These findings are consistent with a potential additive effect of androgens and PA on cardiometabolic outcomes in older men.This article is protected by copyright. All rights reserved. (Source: Clinical Endocrinology)
Source: Clinical Endocrinology - November 26, 2018 Category: Endocrinology Authors: Lauren C. Chasland, Matthew W. Knuiman, Mark L. Divitini, Kevin Murray, David J. Handelsman, Leon Flicker, Graeme J. Hankey, Osvaldo P. Almeida, Jonathan Golledge, Nicola D. Ridgers, Louise H. Naylor, Daniel J. Green, Bu B. Yeap Tags: Original Article Source Type: research

Nomograms for incident risk of postpartum type 2 diabetes in Chinese women with gestational diabetes
This article is protected by copyright. All rights reserved. (Source: Clinical Endocrinology)
Source: Clinical Endocrinology - November 26, 2018 Category: Endocrinology Authors: Edward Janus, James Dunbar Tags: Requested Commentary Source Type: research

Primary aldosteronism is associated with decreased low ‐density and high‐density lipoprotein particle concentrations and increased GlycA, a pro‐inflammatory glycoprotein biomarker
ConclusionsPrimary aldosteronism is associated with lower concentrations of LDL and HDL particles and to some extent also with lower TG and TRL particle concentrations. PA is also characterized by increased GlycA levels, indicating enhanced low ‐grade chronic inflammation. Low HDL particle concentrations and increased GlycA could contribute to accelerated cardiovascular disease development in PA. (Source: Clinical Endocrinology)
Source: Clinical Endocrinology - November 20, 2018 Category: Endocrinology Authors: Annika M. A. Berends, Edward Buitenwerf, Eke G. Gruppen, Wim J. Sluiter, Stephan J. L. Bakker, Margery A. Connelly, Michiel N. Kerstens, Robin P. F. Dullaart Tags: ORIGINAL ARTICLE Source Type: research

Increased mortality and morbidity in patients with chronic hypoparathyroidism: A population ‐based study
ConclusionPatients with hypoparathyroidism have an increased risk of cataract and epilepsy. Non ‐surgical hypoparathyroidism is associated with increased mortality and additional morbidities. (Source: Clinical Endocrinology)
Source: Clinical Endocrinology - November 20, 2018 Category: Endocrinology Authors: Thenmalar Vadiveloo, Peter T. Donnan, Callum J. Leese, Kirstin J. Abraham, Graham P. Leese Tags: ORIGINAL ARTICLE Source Type: research

A 5 α‐reductase (SRD5A2) polymorphism is associated with serum testosterone and sex hormone–binding globulin in men, while aromatase (CYP19A1) polymorphisms are associated with oestradiol and luteinizing hormone reciprocally
ConclusionsA 5 α‐reductase polymorphism predicts circulating T and SHBG, while aromatase polymorphisms predict E2 and LH in reciprocal fashion. Age and aromatase polymorphisms interact to affect E2 and LH. How these functional polymorphisms impact on male reproductive and general health outcomes requires furthe r study. (Source: Clinical Endocrinology)
Source: Clinical Endocrinology - November 19, 2018 Category: Endocrinology Authors: Bu B. Yeap, Matthew W. Knuiman, David J. Handelsman, Ken K. Y. Ho, Jennie Hui, Mark L. Divitini, Gillian M. Arscott, Brendan McQuillan, Joseph Hung, John P. Beilby Tags: ORIGINAL ARTICLE Source Type: research

Cover Image, Volume 89, Issue 6
The cover image is based on the Original ArticleA dense mapping study of six European AITD susceptibility regions in a large Chinese Han Cohort of Graves ’ disease by Wei Liu et al., DOI:10.1111/cen.13847. Design Credit: Qianyue Zhang. (Source: Clinical Endocrinology)
Source: Clinical Endocrinology - November 19, 2018 Category: Endocrinology Authors: Wei Liu, Qian ‐Yue Zhang, Fei‐Fei Yuan, Hai‐Ning Wang, Le‐Le Zhang, Yu‐Ru Ma, Xiao‐Ping Ye, Man‐Man Zhang, Zhi‐Yi Song, Sheng‐Xian Li, Wen‐Hua Du, Jun Liang, Xiao‐Mei Zhang, Guan‐Qi Gao, Shuang‐Xia Zhao, Feng‐lin Tags: COVER IMAGE Source Type: research

Issue Information ‐ TOC and Editorial Board
Clinical Endocrinology, Volume 89, Issue 6, Page 681-682, December 2018. (Source: Clinical Endocrinology)
Source: Clinical Endocrinology - November 19, 2018 Category: Endocrinology Tags: ISSUE INFORMATION Source Type: research

Issue Information ‐ Instructions for Authors
Clinical Endocrinology, Volume 89, Issue 6, Page 889-890, December 2018. (Source: Clinical Endocrinology)
Source: Clinical Endocrinology - November 19, 2018 Category: Endocrinology Tags: ISSUE INFORMATION Source Type: research

Laparoscopic hand ‐assisted adrenalectomy for tumours larger than 5 cm
ConclusionHand ‐assisted laparoscopic surgery offers a safe reproducible approach to adrenal surgery combining minimally invasive surgery with tactile integration. Although previously described in small numbers, this represents the largest case series to date. HAL is a safe minimally invasive surgical option for larger tumours, including malignancies. The HAL technique may additionally offer a shorter learning curve for trainee adrenal surgeons. (Source: Clinical Endocrinology)
Source: Clinical Endocrinology - November 15, 2018 Category: Endocrinology Authors: Jennifer Buxton, Shen H. Vun, David van Dellen, Richard Wadsworth, Titus Augustine Tags: ORIGINAL ARTICLE Source Type: research

Development of a novel risk prediction and risk stratification score for polycystic ovary syndrome
ConclusionsWe propose a simple four ‐variable model, which captures the underlying clinical and hormonal abnormalities in PCOS and can be used for diagnosis and metabolic risk stratification in women with PCOS. (Source: Clinical Endocrinology)
Source: Clinical Endocrinology - November 15, 2018 Category: Endocrinology Authors: Harshal Deshmukh, Maria Papageorgiou, Eric S. Kilpatrick, Stephen L. Atkin, Thozhukat Sathyapalan Tags: ORIGINAL ARTICLE Source Type: research

Paediatric ‐onset and adult‐onset Graves' disease share multiple genetic risk factors
ConclusionsThe results of our study revealed that POGD and AOGD share multiple common genetic risk variants. Moreover, we demonstrated for the first time thatHCP5 polymorphism is associated with an earlier age of GD onset in a dose ‐dependent manner. (Source: Clinical Endocrinology)
Source: Clinical Endocrinology - November 15, 2018 Category: Endocrinology Authors: Aleksander Ku ś, Mikołaj Radziszewski, Aleksandra Glina, Konrad Szymański, Beata Jurecka‐Lubieniecka, Edyta Pawlak‐Adamska, Dorota Kula, Natalia Wawrusiewicz‐Kurylonek, Joanna Kuś, Piotr Miśkiewicz, Rafał Płoski, Marek Bolanowski, Tags: ORIGINAL ARTICLE Source Type: research

Changes of computed tomography ‐based body composition after adrenalectomy in patients with endogenous hypercortisolism
ConclusionsThe severity of cortisol excess was associated with greater improvement of L3 VFA,VSR, and SMD 1 year after adrenalectomy. These CT ‐based markers may allow more objective assessment of treatment benefit at earlier stage.This article is protected by copyright. All rights reserved. (Source: Clinical Endocrinology)
Source: Clinical Endocrinology - November 14, 2018 Category: Endocrinology Authors: Namki Hong, Jooyeon Lee, Cheol Ryong Ku, Kichang Han, Cho Rok Lee, Sang Wook Kang, Yumie Rhee Tags: Original Article Source Type: research

No evidence of adverse fertility and pregnancy outcomes in patients with unrecognized and untreated multiple endocrine neoplasia type 1
ConclusionsThere was no adverse impact of MEN 1 on patient fertility overall; however, MEN 1 ‐related pathology may have impaired the reproductive potential of a subset of individuals with pituitary disease. (Source: Clinical Endocrinology)
Source: Clinical Endocrinology - November 14, 2018 Category: Endocrinology Authors: Michael Thompson, John Burgess Tags: ORIGINAL ARTICLE Source Type: research