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Principles of ethical authorship for publication in Clinical Hemorheology and Microcirculation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19847052 [PubMed - in process] (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - October 24, 2009 Category: Hematology Authors: Gori T, Jung F, Forconi S Tags: Clin Hemorheol Microcirc Source Type: journals

Wavelet analysis of Laser Doppler Flux time series of tumor and inflammatory associated neoangiogenesis. Differences in rhythmical behavior.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We use continuous wavelet analysis (WA) of Laser Doppler Flux (LDF) time series measured in basal cell carcinomas (BCC) and plaque psoriasis (PP) in order to investigate the rhythmical behavior of blood flow in tumor or inflammatory associated neoangiogenesis.A total of 68 patients with primary BCCs and 40 patients with PP were included in the study. LDF time series were separated in four scaling levels corresponding to the influences of sympathetic activity (SL1), myogenic activity in the vessel wall (SL2), respiration (SL3) and heart beat (SL4).In BCC, SL1 decreased compared to healthy skin. In all other scaling leve...
Source: Clinical Hemorheology and Microcirculation - October 24, 2009 Category: Hematology Authors: Häfner HM, Bräuer K, Radke C, Eichner M, Strölin A Tags: Clin Hemorheol Microcirc Source Type: journals

Left ventricular geometry and rheological properties of erythrocytes in patients at cardiovascular disease risk.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The relationship between erythrocyte deformability and aggregability with left ventricular mass index has been examined in patients diagnosed with at least one cardiovascular risk factor but without ongoing coronary heart disease. The group consisted of 66 individuals, 30 men and 36 women, of the average age 57.7 years. For each patient, deformability and aggregability of red blood cells (RBCs) as well as end-diastolic left ventricle diameter (LVD), interventricular septum thickness (IVST) and posterior wall thickness (PWT) were measured. On the basis of the echocardiographical parameters and anthropometric data, left ...
Source: Clinical Hemorheology and Microcirculation - October 24, 2009 Category: Hematology Authors: Fornal M, Korbut RA, Królczyk J, Grodzicki T Tags: Clin Hemorheol Microcirc Source Type: journals

The effect of carotid stenting on rheological parameters, free radical production and platelet aggregation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Hemorheological parameters and platelet aggregation showed specific changes following carotid stenting. Abnormal changes of the rheological conditions and increasing platelet activation are the most pronounced in the first week following stenting, which may lead to early stent occlusion. Oxidative stress production returned to baseline levels only by the end of the first month. PMID: 19847055 [PubMed - in process] (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - October 24, 2009 Category: Hematology Authors: Szapary L, Bagoly E, Kover F, Feher G, Pozsgai E, Koltai K, Hanto K, Komoly S, Doczi T, Toth K Tags: Clin Hemorheol Microcirc Source Type: journals

Impaired red cell deformability in iron deficient subjects.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, the results obtained by optical tweezers showed that iron deficiency affects the elasticity of whole RBC. PMID: 19847056 [PubMed - in process] (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - October 24, 2009 Category: Hematology Authors: Brandão MM, Castro Mde L, Fontes A, Cesar CL, Costa FF, Saad ST Tags: Clin Hemorheol Microcirc Source Type: journals

Lipid peroxidation and total antioxidant status in unprofessional athletes before and after a cardiopulmonary test.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, at baseline in athletes the oxidative status shows a different behaviour compared to controls, while after the test the antioxidant protection is more marked and it may be related to an increase of antioxidant systems. PMID: 19847057 [PubMed - in process] (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - October 24, 2009 Category: Hematology Authors: Caimi G, Canino B, Amodeo G, Montana M, Lo Presti R Tags: Clin Hemorheol Microcirc Source Type: journals

Quantification of the erythrocyte deformability using atomic force microscopy: correlation study of the erythrocyte deformability with atomic force microscopy and hemorheology.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Atomic force microscope (AFM) is a powerful and prospective tool in the studies of the cellular deformability within a single cell. However, the reliability of using AFM in estimating the cellular average deformability was suspected. Hemorheology, one of common clinical examinations, can assess the deformability of erythrocytes. In order to validate the reliability in estimating the cellular deformability with AFM, the correlation was studied between the stiffness of the erythrocyte membrane with AFM and the deformation index with the hemorheology test. Blood samples were taken from 5 diabetes mellitus patients and 5 h...
Source: Clinical Hemorheology and Microcirculation - October 24, 2009 Category: Hematology Authors: Chen X, Feng L, Jin H, Feng S, Yu Y Tags: Clin Hemorheol Microcirc Source Type: journals

Elastase, myeloperoxidase, nitric oxide metabolites and oxidative status in subjects with clinical stable chronic renal failure on conservative treatment.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We evaluated, in a group of 41 CRF undialyzed subjects (29 men and 12 women, mean age 64.1 +/- 11.3 years), some parameters that reflect leukocyte activation (elastase, myeloperoxidase - MPO), plasma NO metabolites (NO(x)) and the oxidative status (lipid peroxidation expressed as thiobarbituric acid-reactive substances (TBARS) and total antioxidant status (TAS). Elastase was determined, on plasma separated from fasting venous blood, as elastase/alpha1-proteinase inhibitor complex. MPO was evaluated employing the Myeloperoxidase ELISA kit. The NO production was evaluated by a micromethod. The oxidation of polyunsaturate...
Source: Clinical Hemorheology and Microcirculation - October 24, 2009 Category: Hematology Authors: Caimi G, Carollo C, Montana M, Vaccaro F, Lo Presti R Tags: Clin Hemorheol Microcirc Source Type: journals

Species-specific effects of anticoagulants on red blood cell deformability.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19847060 [PubMed - in process] (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - October 24, 2009 Category: Hematology Authors: Nemeth N, Baskurt OK, Meiselman HJ, Miko I Tags: Clin Hemorheol Microcirc Source Type: journals

Aspirin resistance in healthy volunteers.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19847061 [PubMed - in process] (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - October 24, 2009 Category: Hematology Authors: Feher G, Pusch G, Szapary L Tags: Clin Hemorheol Microcirc Source Type: journals

Determination of erythrocyte flow velocity by dynamic grey scale measurement using off-line image analysis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19847062 [PubMed - in process] (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - October 24, 2009 Category: Hematology Authors: Liu Y, Yang J, Sun K, Wang C, Han J, Liao F Tags: Clin Hemorheol Microcirc Source Type: journals

Prostaglandin application improves macro- and microcirculation after aorto-hepato-mesenteric bypass in chronic mesenteric ischemia.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19847063 [PubMed - in process] (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - October 24, 2009 Category: Hematology Authors: Rauchfuss F, Scheuerlein H, Ludewig S, Uberrück T, Zanow J, Settmacher U Tags: Clin Hemorheol Microcirc Source Type: journals

Ultrasound contrast agents as markers of vascularity and microcirculation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Ultrasound contrast agents contain tiny gas-filled microbubbles which on intravenous injection are transported like red blood cells by the bloodstream. They are distributed to the entire macro- and microvascular system without extravasation (blood-pool tracer). Contrast-specific ultrasound modalities allow selective imaging of these microbubble contrast agents in real time, with excellent separation from underlying tissue signals. The dynamic wash-in and wash-out of a contrast bolus allows the detection and quantitative assessment of vascular flow and parenchymal perfusion. On complete filling of vascular structures th...
Source: Clinical Hemorheology and Microcirculation - August 29, 2009 Category: Hematology Authors: Greis C Tags: Clin Hemorheol Microcirc Source Type: journals

New perfusion imaging of tissue transplants with Contrast Harmonic Ultrasound Imaging (CHI) and Magnetic Resonance Imaging (MRI) in comparison with laser-induced Indocyanine Green (ICG) fluorescence angiography.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: These first results introduce CHI and MRI perfusion imaging as a promising post-surgery monitoring in patients with free flaps. PMID: 19713598 [PubMed - in process] (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - August 29, 2009 Category: Hematology Authors: Jung EM, Prantl L, Schreyer AG, Schreyer CI, Rennert J, Walter M, Jung W, Hoffstetter P, Herold T, Zorger N, Feuerbach S, Fellner C Tags: Clin Hemorheol Microcirc Source Type: journals

Improvements in high resolution ultrasound for postoperative investigation of capillary microperfusion after free tissue transfer.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: At present, these new US technologies combined with the updated 6-9 MHz probe provide the optimal assessment of perfusion in cutaneous, subcutaneous and deeper tissue layers. The additional use of new multifrequency 6-15 MHz matrix probes improves the resolution in the B-mode to an even higher degree. PMID: 19713599 [PubMed - in process] (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - August 29, 2009 Category: Hematology Authors: Lamby P, Prantl L, Schreml S, Pfister K, Mueller MP, Clevert DA, Jung EM Tags: Clin Hemorheol Microcirc Source Type: journals

The use of antithrombotic agents in microvascular surgery.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Despite increasing advances in microvascular free tissue transfer, flap failures, most commonly resulting from thrombosis at the anastomotic vascular site, remain a significant concern. Although several experimental and clinical studies have been carried out, no consensus has been reached so far on the efficacy, dosage and timing of anticoagulant agents available for the prevention and treatment of thrombosis in microvascular surgery. Inhibition of fibrin formation and platelet function or the use of thrombolytic agents is a common approach in the antithrombotic management. However, some agents exhibit serious side eff...
Source: Clinical Hemorheology and Microcirculation - August 29, 2009 Category: Hematology Authors: Stephan B, Schenk JF, Nemeh A, Pindur G Tags: Clin Hemorheol Microcirc Source Type: journals

New real-time image fusion technique for characterization of tumor vascularisation and tumor perfusion of liver tumors with contrast-enhanced ultrasound, spiral CT or MRI: first results.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Applying a new real-time fusion technique of MD-CT or MRI with CEUS new possibilities for the evaluation, intervention and monitoring of the therapy of liver lesions were made possible, since the method also comprised the dynamic microperfusion. PMID: 19713601 [PubMed - in process] (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - August 29, 2009 Category: Hematology Authors: Jung EM, Schreyer AG, Schacherer D, Menzel C, Farkas S, Loss M, Feuerbach S, Zorger N, Fellner C Tags: Clin Hemorheol Microcirc Source Type: journals

Improving the spatial accuracy in functional magnetic resonance imaging (fMRI) based on the blood oxygenation level dependent (BOLD) effect: benefits from parallel imaging and a 32-channel head array coil at 1.5 Tesla.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, parallel imaging is an alternative to reduce geometric distortions in fMRI at 1.5 T. Using a 32-channel coil, reduction of the voxel size might be the preferable way to improve spatial accuracy. PMID: 19713602 [PubMed - in process] (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - August 29, 2009 Category: Hematology Authors: Fellner C, Doenitz C, Finkenzeller T, Jung EM, Rennert J, Schlaier J Tags: Clin Hemorheol Microcirc Source Type: journals

Contrast-enhanced ultrasound in liver transplant: first results and potential for complications in the postoperative period.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Due to advances in contrast-enhanced US, vascular and biliary complications in the postoperative period following liver transplantation can be reliably diagnosed non-invasively on the intensive care unit. CEUS shows vascular as well as biliary complications in the postoperative patient with a high degree of accuracy. PMID: 19713603 [PubMed - in process] (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - August 29, 2009 Category: Hematology Authors: Clevert DA, Stickel M, Minaifar N, Löhe F, Graeb C, Jauch KW, Reiser M Tags: Clin Hemorheol Microcirc Source Type: journals

Evaluation of Acoustic Radiation Force Impulse (ARFI) imaging and contrast-enhanced ultrasound in renal tumors of unknown etiology in comparison to histological findings.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: ARFI imaging improves visualization of unclear renal masses in comparison to fundamental B-scan and adds new information about the tissue stiffness in a less time-consuming and more reproducible way. CEUS with SonoVue allows an early evaluation of renal masses or complex cysts. PMID: 19713604 [PubMed - in process] (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - August 29, 2009 Category: Hematology Authors: Clevert DA, Stock K, Klein B, Slotta-Huspenina J, Prantl L, Heemann U, Reiser M Tags: Clin Hemorheol Microcirc Source Type: journals

Contrast-enhanced ultrasound in diagnosing liver malignancy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Diminishing of contrast agent in the late phase compared to the arterial phase with respect to the surrounding liver tissue is a helpful sign in contrast enhanced ultrasound to diagnose malignancies. PMID: 19713605 [PubMed - in process] (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - August 29, 2009 Category: Hematology Authors: Zuber-Jerger I, Schacherer D, Woenckhaus M, Jung EM, Schölmerich J, Klebl F Tags: Clin Hemorheol Microcirc Source Type: journals

Contrast harmonic imaging ultrasound and perfusion imaging for surveillance after endovascular abdominal aneurysm repair regarding detection and characterization of suspected endoleaks.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Contrast harmonic imaging (CHI) compared to computed tomography angiography (CTA) accurately depicts endoleaks after endovascular abdominal aneurysm repair and stent-graft procedure in dissected and ulcerated aorta. It seems to be superior in characterization of the type of endoleaks and can be established in order to reduce iodized contrast agent and radiation exposure in follow-up. In contrast to CTA scan CHI can be offered to patients with chronic renal insufficiency and allows a dynamic examination and a perfusion analysis. PMID: 19713606 [PubMed - in process] (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - August 29, 2009 Category: Hematology Authors: Pfister K, Rennert J, Uller W, Schnitzbauer AA, Stehr A, Jung W, Hofstetter P, Zorger N, Kasprzak PM, Jung EM Tags: Clin Hemorheol Microcirc Source Type: journals

Contrast-enhanced ultrasound versus conventional ultrasound and MS-CT in the diagnosis of abdominal aortic dissection.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: With contrast-enhanced ultrasound, diagnostic accuracy sensitivity and specificity for the diagnosis of abdominal aortic dissections is improved as compared to B-scan and CCDS. Dissection membrane and flow within the true and false lumen are clearly differentiated by CEUS. Thus CEUS is a promising alternative for patients whose condition does not allow an examination by CTA. PMID: 19713607 [PubMed - in process] (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - August 29, 2009 Category: Hematology Authors: Clevert DA, Horng A, Clevert DA, Jung EM, Sommer WH, Reiser M Tags: Clin Hemorheol Microcirc Source Type: journals

Quantitative assessment of bowel wall vascularisation in Crohn's disease with contrast-enhanced ultrasound and perfusion analysis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Patients with inflammatory bowel disease (IBD) often undergo several radiologic imaging studies, which - with the exception of magnetic resonance imaging (MRI) and B-scan ultrasound (US) - subject patients to ionizing radiation. With contrast enhanced ultrasound microvascular imaging of the bowel is possible. Hence, the aim of our study was to assess the perfusion pattern of inflamed bowel walls in Crohn's disease compared with healthy volunteers quantitatively using a specific quantification software. We evaluated 4 volunteers and 20 patients with proven Crohn's disease, who went through an active episode based on cli...
Source: Clinical Hemorheology and Microcirculation - August 29, 2009 Category: Hematology Authors: Girlich C, Jung EM, Iesalnieks I, Schreyer AG, Zorger N, Strauch U, Schacherer D Tags: Clin Hemorheol Microcirc Source Type: journals

Permeability of technical and biological tissues.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The permeability of a material is described by the amount of substances (gases, liquids, particles) passing through pores and/or interstices of the material in a certain time. In medicine and biotechnology the permeability is given usually as the amount of water (ml x cm(-2) x min(-1)) permeating per area and time unit through the material. Vascular prostheses are described e.g. as high porous prostheses (e.g. Dacron: 1500-4000 (ml x cm(-2) x min(-1)) or as low porous prostheses (e.g. ePTFE: 200-1000 (ml x cm(-2) x min(-1)). The permeability of blood capillaries is characterized by the exchange of nutrients, metabolite...
Source: Clinical Hemorheology and Microcirculation - August 29, 2009 Category: Hematology Authors: Franke RP, Fuhrmann R, Hiebl B, Mrowietz C, Jung F Tags: Clin Hemorheol Microcirc Source Type: journals

Shear resistance of human umbilical endothelial cells on different materials covered with or without extracellular matrix: controlled in-vitro study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A variety of medical grade polymeric materials are used in tissue engineering and biomedical technology. Dense non-porous polymeric foils were used as substrates for endothelial cell layers. Half a the test samples (polymers and control materials) were seeded with bovine corneal endothelial cells (BCEC) which more or less covered the substrates with an extracellular matrix (ECM) in the consecutive culturing period. Afterwards the ECM covered as well as the uncovered materials were seeded with human umbilical venous endothelial cells (HUVEC). HUVEC seeded samples were cultured either under static or under dynamical cond...
Source: Clinical Hemorheology and Microcirculation - August 29, 2009 Category: Hematology Authors: Hoepken S, Fuhrmann R, Jung F, Franke RP Tags: Clin Hemorheol Microcirc Source Type: journals

Capillary bleeding under oral anticoagulation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: This study shows that capillary bleedings can be demonstrated in patients on oral anticoagulation. Bleedings occur independent of the INR-value. Thus, other factors than the vitamin-k-dependent coagulation effect seem to be causal for the damage of microvessels. Further, the evidence of capillary bleedings is not a prognostic indicator for future hemorrhage. PMID: 19713611 [PubMed - in process] (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - August 29, 2009 Category: Hematology Authors: Leithäuser B, Mrowietz C, Hiebl B, Pindur G, Jung F Tags: Clin Hemorheol Microcirc Source Type: journals

Intravital microscopy of the capillary perfusion in the corium limbi of the third toe of the minipig.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Several methods are available today for the investigation of microcirculation in animal models, but they can be invasive and time-consuming depending on the area investigated. In particular, non-invasive methods that can be conducted rapidly and without dye or tracer injections are in demand. The cutaneous microcirculation can be easily studied in the dorsal corium limbi of the third toe of the porcine forelimb using intravital microscopy - analogous to nail fold capillary microscopy in humans. The capillary microscopy system consists of a reflected-light microscope with a cold light source, green and infrared filters ...
Source: Clinical Hemorheology and Microcirculation - August 29, 2009 Category: Hematology Authors: Hiebl B, Mrowietz C, Braune S, Franke RP, Plendl J, Jung F Tags: Clin Hemorheol Microcirc Source Type: journals

Influence of radiographic contrast media on the secretion of vasoactive substances by primary human umbilical venous endothelial cells (HUVEC): prospective, controlled, in vitro comparative study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Besides the desirable effect of roentgen ray absorption radiographic contrast media (RCM) can also have varying adverse effects. Under discussion, as a possible cause, are microcirculatory disorders resulting from morphological alterations in erythrocytes and endothelial cells. Therefore, the contrast media-induced release of vasoactive substances (prostacyclin, endothelin-1, and nitric oxide (NO)) from human endothelial cells (HUVEC) induced by two commercially available RCMs (Iodixanol 320, Iomeprol 350) was tested in a controlled in-vitro study. The results show that RCMs lead to endothelial cell trauma in vitro, wh...
Source: Clinical Hemorheology and Microcirculation - August 29, 2009 Category: Hematology Authors: Franke RP, Fuhrmann R, Hiebl B, Jung F Tags: Clin Hemorheol Microcirc Source Type: journals

Hemorheology and circulation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The main functions of the blood are the transport, and delivery of oxygen and nutrients, removal of carbon dioxide and waste products of metabolism, distribution of heat and signals of immune system. They are provided by circulation due to the driving force of the heart. Circulation of the blood depends on its rheological properties of the blood as well as on characteristics of the vessels through which the blood passes. The blood flow resistance is influenced by the complicated architecture of the vascular network and flow behaviour of blood components - blood cells and plasma. The obtained data based on analysis of i...
Source: Clinical Hemorheology and Microcirculation - July 25, 2009 Category: Hematology Authors: Marossy A, Svorc P, Kron I, Gresová S Tags: Clin Hemorheol Microcirc Source Type: journals

Immunohistochemical evaluation of microvascular rarefaction in hypertensive humans and in spontaneously hypertensive rats.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Our results suggest that, in the brain and skeletal muscle of adult SHR after the development of hypertension, and in the derma of adult essential hypertensive patients microvascular rarefaction may occur. PMID: 19628891 [PubMed - in process] (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - July 25, 2009 Category: Hematology Authors: Paiardi S, Rodella LF, De Ciuceis C, Porteri E, Boari GE, Rezzani R, Rizzardi N, Platto C, Tiberio GA, Giulini SM, Rizzoni D, Agabiti-Rosei E Tags: Clin Hemorheol Microcirc Source Type: journals

Low dose aprotinin and low dose tranexamic acid in elective cardiac surgery with cardiopulmonary bypass.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The antifibrinolytic agents aprotinin and tranexamic acid have both been proven to be efficient in reducing postoperative blood loss and transfusion requirements in patients in cardiac surgery. In light of recent safety issues regarding aprotinin, this single-centre study compared efficacy and safety of low dose aprotinin (2 million KIU, pump-prime volume only) and low dose tranexamic acid (1 g, pump-prime volume) in 708 consecutive patients from two prospective registers undergoing elective cardiac procedures with cardiopulmonary bypass (CPB). Incidences of postoperative complications showed no significant differences...
Source: Clinical Hemorheology and Microcirculation - July 25, 2009 Category: Hematology Authors: Waldow T, Krutzsch D, Wils M, Plötze K, Matschke K Tags: Clin Hemorheol Microcirc Source Type: journals

The rheological profile of chronic liver disease patients in Nigeria.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: CLD patients had low blood viscosity and low fibrinogen level (hypofibrinogenamia) when compared to controls. This may have contributed to the hypocoagulable state and therefore the bleeding tendency encountered in these patients. PMID: 19628893 [PubMed - in process] (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - July 25, 2009 Category: Hematology Authors: Omoti CE, Omuemu CE, Olu-Eddo AN Tags: Clin Hemorheol Microcirc Source Type: journals

Correlation of microvascular abnormalities and endothelial dysfunction in Type-1 Diabetes Mellitus (T1DM): A real-time intravital microscopy study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We hypothesize that real-time in vivo microvascular abnormalities should correlate with biochemical markers of inflammation/endothelial dysfunction in T1DM. Real-time quantification of T1DM and healthy non-diabetic control microcirculation was conducted utilizing computer-assisted intravital microscopy. Selected biochemical markers (high sensitivity C-reactive protein (hsCRP), soluble vascular cell adhesion molecules (sVCAM), soluble intercellular adhesion molecules (sICAM), soluble E-selectin (sE-selectin), nitrotyrosine, superoxide anion (O2-), interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha (TNF-alpha))...
Source: Clinical Hemorheology and Microcirculation - July 25, 2009 Category: Hematology Authors: Cheung AT, Smith Tomic MM, Chen PC, Miguelino E, Li CS, Devaraj S Tags: Clin Hemorheol Microcirc Source Type: journals

Effect of tourniquet application during blood sampling on RBC deformability and aggregation: Is it better to keep it on?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We have recently demonstrated that the use of a tourniquet to locate the vein prior to blood sampling may affect red blood cell (RBC) deformability and aggregation, even if the tourniquet is quickly removed after insertion of the needle into the vein. However, in clinical practice, the tourniquet is usually kept in place until blood sampling is completed. The present study tested the effects of tourniquet application during the blood sampling period on RBC deformability and aggregation. We compared blood samples obtained at 5, 30, 60 and 90 seconds following the tourniquet application; a control blood sample was obtain...
Source: Clinical Hemorheology and Microcirculation - July 25, 2009 Category: Hematology Authors: Connes P, Nemeth N, Meiselman HJ, Baskurt OK Tags: Clin Hemorheol Microcirc Source Type: journals

Increased blood viscosity: Disease, adaptation or treatment?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19628897 [PubMed - in process] (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - July 25, 2009 Category: Hematology Authors: Intaglietta M Tags: Clin Hemorheol Microcirc Source Type: journals

Author index volume 42 (2009).Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: PMID: 19628898 [PubMed - in process] (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - July 25, 2009 Category: Hematology Tags: Clin Hemorheol Microcirc Source Type: journals

The evolution of the meaning of blood hyperviscosity in cardiovascular physiopathology: should we reinterpret Poiseuille?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19363235 [PubMed - in process] (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - June 27, 2009 Category: Hematology Authors: Forconi S, Gori T Tags: Clin Hemorheol Microcirc Source Type: journals

The attenuation effect of 3,4-dihydroxy-phenyl lactic acid and salvianolic acid B on venular thrombosis induced in rat mesentery by photochemical reaction.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
3,4-dihydroxy-phenyl lactic acid (DLA) and salvianolic acid B (SAB) are two major water-soluble components of Salvia miltiorrhiza (SM). Previous works have revealed the ability of DLA and SAB to scavenge oxygen free radicals, inhibiting the expression of adhesion molecules CD11b/CD18 in neutrophil. Cardiotonic pills (CP), which is a traditional Chinese medicine compound preparation containing DLA and SAB, was found to inhibit venular thrombosis induced by photochemical reaction (PR) in rat mesentery. The present study addressed the effect of DLA and SAB on PR-induced thrombosis in rat mesentery by utilizing a microcirc...
Source: Clinical Hemorheology and Microcirculation - June 27, 2009 Category: Hematology Authors: Wang F, Liu YY, Liu LY, Zeng QJ, Wang CS, Sun K, Yang JY, Guo J, Fan JY, Han JY Tags: Clin Hemorheol Microcirc Source Type: journals

Effect of Sclerovit on endothelial dysfunction, hemorheological parameters, platelet aggregation, plasma concentration of homocysteine and progression of atherosclerosis in patients with vascular diseases.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In our prospective study the effect of Sclerovit (0.8 mg folic acid, 20 mug vitamin B12,5 mg vitamin B6,100 mg vitamin E) on inflammatory markers, hemorheological parameters, platelet aggregation, von Willebrand factor activity as a marker of endothelium dysfunction, plasma lipids, plasma levels of folic acid, vitamin B12 and homocysteine (hcy), flow mediated vasodilatation (FMD) and thickness of carotis intima-media after 1 and 6 months of treatment in patients with vascular diseases (10 patients took 1 capsule, 10 patients 2 capsules of Sclerovit and 10 patients placebo) was determined.Plasma level of vitamin B12, fo...
Source: Clinical Hemorheology and Microcirculation - June 27, 2009 Category: Hematology Authors: Horvath B, Szapary L, Debreceni L, Feher G, Kenyeres P, Fulop A, Battyani I, Toth K Tags: Clin Hemorheol Microcirc Source Type: journals

Improving abnormal hemorheological parameters in ApoE-/- mice by Ilex kudingcha total saponins.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, the Ilex kudingcha total saponins may have a significant therapy application of hypercholesterolemia and atherosclerosis by considering its actions on hemorheological characteristics. PMID: 19363238 [PubMed - in process] (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - June 27, 2009 Category: Hematology Authors: Zheng J, Wang X, Li H, Gu Y, Tu P, Wen Z Tags: Clin Hemorheol Microcirc Source Type: journals

The importance of rheological parameters in the therapy of microcirculatory disorders.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study we describe the changes of effectivity indicators in haemorheopheresis treatment and their clinical importance in cases of eye microcirculation, statoacoustic apparatus and disorders of the lower extremities. We treated with haemorheopheresis (separator Cobe.Spetra + Evaflux filter) 24 patients (16 patients with age related macular degeneration, 5 with critical peripheral arterial foot disease, and 3 with acute hearing loss). After the procedures alpha2-macroglobulin decreases by about 58%, fibrinogen by about 69%, IgM by about 61%, LDL-cholesterol by about 77%, apolipoprotein B by about 76% and lipoprotein(a...
Source: Clinical Hemorheology and Microcirculation - June 27, 2009 Category: Hematology Authors: Bláha M, Rencová E, Bláha V, Malý R, Blazek M, Studnicka J, Andrýs C, Fátorová I, Filip S, Kasparová M, Procházková R, Malý J, Zimová R, Langrová H Tags: Clin Hemorheol Microcirc Source Type: journals

Red blood cell-deformability measurement: review of techniques.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Cell-deformability characterization involves general measurement of highly complex relationships between cell biology and physical forces to which the cell is subjected. The review takes account of the modern technical solutions simulating the action of the force applied to the red blood cell in macro- and microcirculation. Diffraction ektacytometers and rheoscopes measure the mean deformability value for the total red blood cell population investigated and the deformation distribution index of individual cells, respectively. Deformation assays of a whole single cell are possible by means of optical tweezers. The singl...
Source: Clinical Hemorheology and Microcirculation - June 27, 2009 Category: Hematology Authors: Musielak M Tags: Clin Hemorheol Microcirc Source Type: journals

Yasmin and venous thromboembolism: new case reports.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present a serie of eight new cases of women who developed thrombotic events early after starting on Yasmin who were sent to our Thrombosis and Hemostasis Unit for a thrombophilia work-up in the last five years. Only two of them were heterozygous carriers of the prothrombin G20210A mutation and three were obese while none of them were smoker. These new cases provide information about the characteristics of the thrombotic events and the concomitant risk factors, indicating that this pill may not be as safe as had been previously thought, and suggest that new studies regarding safety profile of Yasmin are required to expla...
Source: Clinical Hemorheology and Microcirculation - June 27, 2009 Category: Hematology Authors: López M, Vayá A, Martínez Triguero ML, Contreras MT, Todolí J, Ricart A, Laiz B Tags: Clin Hemorheol Microcirc Source Type: journals

The criteria for evaluating shear stress measuring range and the lowest measurable shear stress of rotational viscometer.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19363242 [PubMed - in process] (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - June 27, 2009 Category: Hematology Authors: Qi Q, Li Y, You Y, Liao F Tags: Clin Hemorheol Microcirc Source Type: journals

New guidelines for hemorheological laboratory techniques.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19433882 [PubMed - in process] (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - June 27, 2009 Category: Hematology Authors: Baskurt OK, Boynard M, Cokelet GC, Connes P, Cooke BM, Forconi S, Liao F, Hardeman MR, Jung F, Meiselman HJ, Nash G, Nemeth N, Neu B, Sandhagen B, Shin S, Thurston G, Wautier JL, Tags: Clin Hemorheol Microcirc Source Type: journals

Nailfold capillaroscopy: Specific features in Fabry disease.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: In Fabry disease morphological and functional microangiopathy of nailfold capillaries is present. Furthermore, these new findings might explain, at least in part, the unusual high frequency of Raynaud phenomenon in Fabry patients, which has not been described so far. Our data suggest that capillaroscopy might be used as an additional non-invasive diagnostic tool for Fabry disease. PMID: 19433883 [PubMed - in process] (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - June 27, 2009 Category: Hematology Authors: Wasik JS, Simon RW, Meier T, Steinmann B, Amann-Vesti BR Tags: Clin Hemorheol Microcirc Source Type: journals

Study of skin vasomotion during phollicular and luteal phase in young healthy women.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The aim of this study was to evaluate if changes in female sex hormones associated to follicular phase (FP) and luteal phase (LP) may affect skin vasomotion in women with evidence of ovulatory cycle. Nine healthy non-smoker women aged 25+/-4 years, with regular menstrual cycle of 28+/-2 days and evidence of ovulation (indicated by a mid-luteal serum progesterone concentration > 5 ng/ml) (group-1) and six healthy non-smoker healthy women aged 24+/-2 years with evidence of an-ovulatory cycle (group-2) were enrolled in the study. At the times 1 (7th-10th day from the beginning of the last menstrual cycle) and at the ti...
Source: Clinical Hemorheology and Microcirculation - June 27, 2009 Category: Hematology Authors: Rossi M, Di Maria C, Erba P, Galetta F, Carpi A, Santoro G Tags: Clin Hemorheol Microcirc Source Type: journals

A transient, microfluidic approach to the investigation of erythrocyte aggregation: the threshold shear-stress for erythrocyte disaggregation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Detailed analysis of red blood cells (RBCs) aggregation is often required in various clinical studies. Most conventional aggregation indices are dimensionless values and not available for comparison of across studies. Quite recently, we have developed microfluidic aggregometry that enables us to yield a critical shear-stress that are required to aggregate RBCs under the shearing hydrodynamic force. The present study investigated the relationships between the values of the critical shear-stress and conventional aggregation indices by comparing the critical shear-stress measured by the microfluidic aggregometry with the ...
Source: Clinical Hemorheology and Microcirculation - June 27, 2009 Category: Hematology Authors: Shin S, Nam JH, Hou JX, Suh JS Tags: Clin Hemorheol Microcirc Source Type: journals

Blood rheology at term in normal pregnancy and in patients with adverse outcome events.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Plasma volume expansion of more than 1.5 l and sustainable activation of the hemostatic system that results in a steady rise of the fibrinogen/fibrin turnover are contemporary physiological events during normal pregnancy. In contrast, adverse outcome of pregnancy i.e. pre-eclampsia commonly coincide with hemo concentration and over activation of blood coagulation both of which alter blood rheology. On the basis of 4,985 consecutively recorded singleton pregnancies values range of blood rheological parameters in women with normal and complicated outcome of pregnancy at the time of their delivery were compared. Plasma vi...
Source: Clinical Hemorheology and Microcirculation - June 27, 2009 Category: Hematology Authors: von Tempelhoff GF, Velten E, Yilmaz A, Hommel G, Heilmann L, Koscielny J Tags: Clin Hemorheol Microcirc Source Type: journals