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Can health promotion programs save Medicare money?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Ron Z Goetzel1, David Shechter2, Ronald J Ozminkowski1, David C Stapleton3, Pauline J Lapin4, J Michael McGinnis5, Catherine R Gordon6, Lester Breslow71Institute for Health and Productivity Studies, Cornell University, Washington, DC; 2Health and Productivity Research, Thomson Medstat, Santa Barbara, CA; 3Cornell Institute for Policy Research, Cornell University, Washington, DC; 4Office of Research, Development, and Information, Centers for Medicare and Medicaid Services, Baltimore, MD; 5National Academy of Sciences, Institute of Medicine, The National Academies, Washington, DC; 6Office of the Director, Centers for Disease...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Patient preference in the management of postmenopausal osteoporosis with bisphosphonatesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Jean-Yves Reginster, Véronique RabendaWHO Collaborating Center for Public Health Aspects of Rheumatic Diseases, University of Liege, Liege, BelgiumAbstract: The leading treatments for postmenopausal osteoporosis are the nitrogen-containing bisphosphonates, which are required long term for optimal benefit. Oral bisphosphonates have proven efficacy in postmenopausal osteoporosis in clinical trials, but in practice the therapeutic benefits are often compromised by patients’ low adherence. Nonadherence to bisphosphonate therapy negatively impacts outcomes such as fracture rate; fractures are in turn associated wit...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Doxazosin in the treatment of benign prostatic hypertrophy: an updateEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Timothy J Wilt, Roderick MacDonaldMinneapolis Veterans Affairs Center for Chronic Disease Outcomes Research, the Cochrane Review Group in Prostate Diseases and Urologic Cancers, Veterans Affairs Medical Center, Minneapolis, USAAbstract: We evaluated the efficacy and safety of a1 - blocker doxazosin for treatment of lower urinary tract symptoms (LUTS) compatible with benign prostatic hypertrophy (BPH). Fourteen randomized controlled trials enrolled 6261 men, average age 64 years, who had moderately severe LUTS and flow impairment. Compared with baseline measures and placebo effect, doxazosin resulted in a statistically sign...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Comparative effects of antiresorptive agents on bone mineral density and bone turnover in postmenopausal womenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article reviews the currently available antiresorptive agents and their effects on the above outcome measures.Keywords: osteoporosis, postmenopausal, fracture, antiresorptive agents
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Strontium ranelate: a novel treatment for postmenopausal osteoporosis: a review of safety and efficacyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Glen M Blake, Ignac FogelmanKing’s College London School of Medicine, London, UKAbstract: Strontium ranelate is a new orally administered agent for the treatment of women with postmenopausal osteoporosis that reduces the risk of vertebral and hip fractures. Evidence for the safety and efficacy of strontium ranelate comes from two large multinational trials, the SOTI (Spinal Osteoporosis Therapeutic Intervention) and TROPOS (Treatment Of Postmenopausal Osteoporosis) studies. The SOTI study evaluated vertebral fracture prevention in 1649 postmenopausal women with a mean age of 69 y. The subjects all had at least one pr...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Principles of soft tissue augmentation for the aging faceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Cheryl M BurgessCenter for Dermatology and Dermatologic Surgery, 2311 M Street, Northwest, Suite 504, Washington, D.C. 20037, USAAbstract: In the quest for the “ideal” soft tissue filler, many diverse products have been developed. The expanding market of available fillers is a testament that no one product will ideally suit all patients or clinicians. In addition, the challenge of satisfying the criteria of an ideal filler has driven researchers to take a variety of development paths. This has resulted in multiple categories to characterize soft tissue fillers. These fillers are categorized according to: (1) fi...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Utility of tolcapone in fluctuating Parkinson’s diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Fabrizio Stocchi1, Maria Francesca De Pandis21IRCCS San Raffaele Pisana, Roma, Italy; 2San Raffaele Cassino (FR), Roma, ItalyAbstract: Fluctuating Parkinson’s disease (PD) represents a clinical management challenge. The primary utility of levodopa in patients with PD is moderated by the “wearing off” phenomena seen with long-term use. COMT inhibitors slow down the rapid metabolism of levodopa, resulting in a more-sustained response to dopaminergic therapy. Tolcapone is a selective, reversible catechol-O-methyltransferase (COMT) inhibitor, shown to have both peripheral and central effects. In clinical tria...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Treatment of overactive bladder in the aging population: focus on darifenacinEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Swati Jha, Matthew ParsonsDepartment of Urogynaecology, Birmingham Women’s Hospital, Birmingham. UKAbstract: Anticholinergics are commonly used in primary and secondary care settings for the treatment of overactive bladder syndrome. The number of anticholinergic drugs available on the market is increasing and various studies, both observational and randomized controlled trials, have evaluated effectiveness of the different preparations available. When anticholinergic therapy is prescribed, there is still uncertainty about which anticholinergic drugs are most effective, at which dose, and by which route of administrat...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Editorial: Developing better therapies through collegial interaction ||Free Paper||Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Richard F WalkerInternational Society for Applied Research in Aging (SARA)The Society for Applied Research in Aging (SARA) was founded to serve the needs of practitioners who seek to sustain health, vitality, and quality of life of their patients during aging. Recognizing that a most basic and important part of that task is to provide relevant professional information to its members, Clinical Interventions in Aging (CIA) was created as the official SARA journal.
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Editorial: Challenges facing age-management/longevity medicine ||Free Paper||Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Richard F WalkerInternational Society for Applied Research in Aging (SARA)Prior to the discovery of penicillin and production of antibiotics, extrinsic disease was the greatest threat to achieving maximum life potential (longevity). That single event increased life-span several decades for the majority of people living in first world nations. However, protection against lethal infection provided by antibiotics exposed older humans to a wide variety of life-threatening diseases resulting from disintegration of internal order during senescence. These intrinsic diseases including diabetes, stroke, heart attack, cancer, and a ...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Impact of extracorporeal shock waves on the human skin with cellulite: A case study of an unique instanceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Christoph Kuhn1, Fiorenzo Angehrn1, Ortrud Sonnabend2, Axel Voss31Klinik Piano, Biel, Switzerland; 2Pathodiagnostics, Herisau, Switzerland; 3SwiTech Medical AG, Kreuzlingen, SwitzerlandAbstract: In this case study of an unique instance, effects of medium-energy, high-focusedextracorporeal generated shock waves (ESW) onto the skin and the underlying fat tissue of acellulite afflicted, 50-year-old woman were investigated. The treatment consisted of four ESW applications within 21 days. Diagnostic high-resolution ultrasound (Collagenoson) was performed before and after treatment. Directly after the last ESW application, skin ...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Classifying late-onset dementia with MRI: Is arteriosclerotic brain degeneration the most common cause of Alzheimer’s syndrome?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, these observations enhance the pathogenic complexity of the Alzheimer syndrome, and suggest that the role of arteriosclerotic brain degeneration in late life dementia is underestimated.Keywords: Alzheimer’s disease, mild cognitive impairment, dementia, MRI, phase contrast, atherosclerosis
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

The effect of a combined oral calcium and vitamin D supplement for treating mild to moderate vitamin D deficiency in postmenopausal womenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: A combined oral Ca-D3 product (Osteoblast) is effective for treating vitamin D deficiency and is adequately tolerated.
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Extracorporeal shock waves as curative therapy for varicose veins?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Fiorenzo Angehrn1, Christoph Kuhn1, Ortrud Sonnabend2, Axel Voss31Klinik Piano, Biel, Switzerland; 2Pathodiagnostics, Herisau, Switzerland; 3SwiTech Medical AG, Kreuzlingen, SwitzerlandAbstract: In this prospective design study the effects of low-energy partially focused extracorporeal generated shock waves (ESW) onto a subcutaneous located varicose vein – left vena saphena magna (VSM) – are investigated. The treatment consisted of 4 ESW applications within 21 days. The varicose VSM of both sides were removed by surgery, and samples analyzed comparing the treated and untreated by means of histopathology. No dam...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Use of calcium hydroxylapatite (Radiesse®) for facial augmentationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Patricio F JacovellaHospital de Clinicas, University of Buenos Aires, ArgentinaAbstract: Radiesse® (Bioform Inc, USA) is a sterile, latex-free, non-pyrogenic, semi-solid, cohesive subdermal, injectable implant, whose principal component is synthetic calcium hydroxylapatite, a biocompatible material with over 20 years of use in medicine. The semi-solid nature of the product is created by suspending calcium hydroxylapatite microspheres of 25–45 microns diameter in a gel carrier of carboxymethylcellulose. The product has FDA approval for esthetic facial augmentation in the US. Such approval includes the long-lasting...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Hyaluronic acid gel fillers in the management of facial agingEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article reviews the innate properties of FDA-approved HA fillers and provides an insight on future HA products and their utilization for the management of the aging face.Keywords: hyaluronic acid, aging face, dermal filler, wrinkles, Restylane, Perlane, Juvéderm
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Vocal aging and adductor spasmodic dysphonia: Response to botulinum toxin injectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Michael P Cannito, Joel C Kahane, Lesya ChornaSchool of Audiology and Speech-Language Pathology, The University of Memphis, Memphis, TN, USAAbstract: Aging of the larynx is characterized by involutional changes which alter its biomechanical and neural properties and create a biological environment that is different from younger counterparts. Illustrative anatomical examples are presented. This natural, non-disease process appears to set conditions which may influence the effectiveness of botulinum toxin injection and our expectations for its success. Adductor spasmodic dysphonia, a type of laryngeal dystonia, is typically ...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Growth hormone (GH)–releasing hormone and GH secretagogues in normal aging: Fountain of Youth or Pool of Tantalus?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Elizabeth C Hersch, George R MerriamVA Puget Sound Health Care System and University of Washington School of Medicine, Tacoma and Seattle, Washington USAAbstract: Although growth hormone (GH) is primarily associated with linear growth in childhood, it continues to have important metabolic functions in adult life. Adult GH deficiency (AGHD) is a distinct clinical entity, and GH replacement in AGHD can improve body composition, strength, aerobic capacity, and mood, and may reduce vascular disease risk. While there are some hormone-related side effects, the balance of benefits and risks is generally favorable, and several cou...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Pharmacological treatment of neuropathic pain in older personsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Clair Haslam1, Turo Nurmikko21The Walton Centre for Neurology and Neurosurgery, Liverpool, England, UK; 2The Pain Research Institute, Division of Neurological Science, University of Liverpool, Liverpool, England, UKAbstract: Interest and research into the mechanisms and treatment of neuropathic pain have increased during recent years, but current treatment is still far from satisfactory (Dworkin et al 2003; Attal et al 2006). The European Federation of Neurological Societies (EFNS) Task Force recently published guidelines for the pharmacological treatment of neuropathic pain (Attal et al 2006). However, no particular consi...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Effectiveness of the Mediterranean diet in the elderlyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Blanca Roman1, Laura Carta2, Miguel Ángel Martínez-González3, Lluís Serra-Majem41Mediterranean Diet Foundation, University of Barcelona Science Park, Spain; 2Department of Biosystems and Applied Sciences, Unit of Physiology and Human Nutrition, University of Cagliari, Italy; 3Department of Epidemiology and Public Health, University of Navarra, Spain; 4Department of Clinical Sciences, University of Las Palmas de Gran Canaria, SpainAbstract: The Mediterranean diet is known to be one of the healthiest dietary patterns in the world due to its relation with a low morbidity and mortality for some chro...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

A coping and communication support intervention tailored to older patients diagnosed with late-stage cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Julia Hannum Rose1,2,3, Rosanne Radziewicz4, Karen F Bowman5, Elizabeth E O’Toole11Case Western Reserve University School of Medicine, Cleveland, OH, USA; 2Louis Stokes Cleveland VAMC-GRECC, Cleveland, OH, USA; 3Center for Health Care Research and Policy, Case at MetroHealth Medical Center, Cleveland, OH, USA; 4Department of Nursing, MetroHealth Medical Center, Cleveland, OH, USA; 5Department of Sociology, Case Western Reserve University, Cleveland, OH, USAAbstract: As our society ages, increasing numbers of older Americans will be diagnosed and eventually will die of cancer. To date, psycho-oncology interventions fo...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

A review of tazarotene in the treatment of photodamaged skinEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Stephanie Ogden1, Miny Samuel2, Christopher EM Griffiths11Dermatology Centre, University of Manchester, Hope Hospital, Salford Manchester, M6 8HD, UK; 2RTI-Health Solutions, Williams House, Manchester Science Park, Lloyd Street North, Manchester M15 6SE, UKAbstract: Chronic sun exposure leads to photodamage, which is characterized clinically by fine and coarse wrinkles, dyspigmentation, telangiectasia, laxity, roughness and a sallow appearance. Many treatments claim to reduce the signs of photodamage, however evidence from randomized controlled trials (RCT) to support these claims is limited. The use of topical retinoids, ...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Carvedilol in the treatment of elderly patients with chronic heart failureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Klaus KA Witte1, Andrew L Clark21Academic Department of Cardiology, LIGHT Building, University of Leeds and Leeds General Infirmary, UK; 2Academic Department of Cardiology, Castle Hill Hospital, University of Hull, Hull, UKAbstract: Chronic heart failure (CHF) is common, and increases in incidence and prevalence with age. There are compelling data demonstrating reduced mortality and hospitalizations with adrenergic blockade in older patients with CHF. Despite this, many older patients remain undertreated. The aim of the present article is to review the potential mechanisms of the benefits of adrenergic blockade in CHF and ...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Transdermal hormone therapy and bone healthEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Lee P ShulmanDivision of Reproductive Genetics, Department of Obstetrics and Gynecology, Feinberg School of Medicine of Northwestern University, Chicago, Illinois, USAAbstract: The clinical aftermath of the reporting of the initial findings of the Women’s Health Initiative (WHI) in 2002 was a profound reduction in the use of hormone therapies by menopausal women. This reduction led to a well documented increase in vasomotor symptoms and vaginal atrophy among those women who discontinued their hormone regimens. However, another adverse impact among these women, as well as many other menopausal women, is the well recog...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Raloxifene for older women: a review of the literatureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Helga HansdóttirDepartment of Geriatrics, Landspitali University Hospital, Landakoti, Reykjavik, IcelandAbstract: Raloxifene is a non-steroidal selective estrogen-receptor modulator (SERM) which is used for prevention and treatment of postmenopausal osteoporosis. Raloxifene decreases the incidence of vertebral fractures by 30%–50% in postmenopausal women with osteoporosis but has not been shown to decrease the incidence of hip fractures or other non-vertebral fractures. At the present time, estrogen-replacement therapy and bisphosphonate treatment are the only medical treatments that are proven to prevent hip ...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Testosterone for the aging male; current evidence and recommended practiceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Roger D Stanworth, T Hugh JonesCentre of Diabetes and Endocrinology, Barnsley Hospital NHS Foundation Trust, Barnsley, South Yorkshire, United Kingdom; Academic Unit of Diabetes, Endocrinology and Metabolism, University of Sheffield, Sheffield, South Yorkshire, United KingdomAbstract: An international consensus document was recently published and provides guidance on the diagnosis, treatment and monitoring of late-onset hypogonadism (LOH) in men. The diagnosis of LOH requires biochemical and clinical components. Controversy in defining the clinical syndrome continues due to the high prevalence of hypogonadal symptoms in th...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Management of peripheral arterial disease in the elderly: focus on cilostazolEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Travis M Falconer1, John W Eikelboom2, Graeme J Hankey3, Paul E Norman11School of Surgery, University of Western Australia, Fremantle Hospital, Western Australia; 2Department of Medicine, McMaster University, Hamilton, Canada; 3Department of Neurology, Royal Perth Hospital, School of Medicine and Pharmacology, University of Western AustraliaAbstract: Symptomatic and asymptomatic peripheral arterial disease (PAD) is a common problem in the elderly. The management of PAD includes the prevention of cardiovascular events and relief of symptoms – most commonly intermittent claudication (IC). Both require treatment of the ...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

HT update: spotlight on estradiol/norethindrone acetate combination therapyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Colleen L Casey, Christine A MurrayUniversity of Vermont, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Burlington, VT, USAAbstract: The goal of postmenopausal hormone therapy is to alleviate the symptoms that are associated with the loss of estrogen. Many formulations of estrogen and progestin are available, depending on the needs and circumstances of each individual woman. For postmenopausal women, the choice of whether or not to begin therapy requires knowledge of the risks and benefits of estrogen and/or progestin replacement. The purpose of this review is to describe ...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Role of androgens, progestins and tibolone in the treatment of menopausal symptoms: a review of the clinical evidenceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Maria Garefalakis, Martha HickeySchool of Women’s and Infants’ Health, The University of Western Australia, King Edward Memorial Hospital, Subiaco, Western Australia, AustraliaAbstract: Estrogen-containing hormone therapy (HT) is the most widely prescribed and wellestablished treatment for menopausal symptoms. High quality evidence confirms that estrogen effectively treats hot flushes, night sweats and vaginal dryness. Progestins are combined with estrogen to prevent endometrial hyperplasia and are sometimes used alone for hot flushes, but are less effective than estrogen for this purpose. Data are conflicting ...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Editorial Foreword: Comments on “Growth hormone (GH)-releasing hormone and GH secretagogues in normal aging” || FREE PAPER ||Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Richard F WalkerInternational Society for Applied Research in Aging (SARA)This issue of Clinical Interventions in Aging contains a quite interesting and informative article about a topic that is popular and also controversial among practitioners of age-management medicine. Appropriate to that controversy, Drs Hersch and Merriam (2008) have asked the question in the title of their paper, does the use of growth hormone secretagogues in age management medicine hold the promise of a fountain of youth, or that of a pool of Tantalus? While there is universal understanding of the fountain imagery, the meaning of the pool is perha...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Predictors of adherence to physical activity in the Lifestyle Interventions and Independence for Elders pilot study (LIFE-P)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Discussion: These results are encouraging in that the physical activity intervention appears to have been well tolerated by diverse subgroups of older adults. The role of prior behavior in predicting downstream adherence underscores the importance of developing proactive interventions for treating nonadherence in older adult populations.Keywords: Disability, Physical Activity, Older Adults, Adherence
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Effects of antioxidant supplementation on the aging processEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Domenico Fusco1, Giuseppe Colloca1, Maria Rita Lo Monaco1, Matteo Cesari1,21Department of Gerontology, Geriatrics and Physiatry; Catholic University of Sacred Heart, Rome, Italy; 2Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, FLAbstract: The free radical theory of aging hypothesizes that oxygen-derived free radicals are responsible for the age-related damage at the cellular and tissue levels. In a normal situation, a balanced-equilibrium exists among oxidants, antioxidants and biomolecules. Excess generation of free radicals may overwhelm natural ce...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Effects of intergenerational Montessori-based activities programming on engagement of nursing home residents with dementiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Michelle M Lee1, Cameron J Camp2, Megan L Malone21Midwestern University, Department of Behavioral Medicine, Downers Grove, IL , USA; 2Myers Research Institute of Menorah Park Center for Senior Living, Beachwood, OH, USA Abstract: Fourteen nursing home residents on a dementia special care unit at a skilled nursing facility took part in one-to-one intergenerational programming (IGP) with 15 preschool children from the facility’s on-site child care center. Montessori-based activities served as the interface for interactions between dyads. The amount of time residents demonstrated positive and negative forms of engagemen...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Treatment of specific phobia in older adultsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nancy A Pachana1, Rana M Woodward1, Gerard JA Byrne21School of Psychology, University of Queensland, Brisbane, Australia 2School of Medicine, University of Queensland, Brisbane, AustraliaAbstract: Phobias are common in later life, yet treatment research in this population remains scant. The efficacy of exposure therapy, in combination with other Cognitive-Behavioral Therapy (CBT) components, in the treatment of specific phobia with a middle and older aged sample was examined. Sixteen adults aged 45–68 with DSM-IV diagnosis of a specific phobia received a manualized intervention over ten weeks, and were compared with ...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

The therapeutic effects of the physician-older patient relationship: Effective communication with vulnerable older patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Summer L Williams, Kelly B Haskard, M Robin DiMatteoDepartment of Psychology, University of California, Riverside, CA, USA Abstract: There is growing evidence that the outcomes of health care for seniors are dependent not only upon patients’ physical health status and the administration of care for their biomedical needs, but also upon care for patients’ psychosocial needs and attention to their social, economic, cultural, and psychological vulnerabilities. Even when older patients have appropriate access to medical services, they also need effective and empathic communication as an essential part of their trea...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Patterns of intimate partner homicide suicide in later life: Strategies for preventionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Sonia SalariDepartment Family and Consumer Studies, University of Utah, Salt Lake City, UT, USAAbstract: Intimate partner homicide suicide (IPHS) constitutes the most violent domestic abuse outcome, devastating individuals, families, neighborhoods and communities. This research used content analysis to analyze 225 murder suicide events (444 deaths) among dyads with at least one member 60 or older. Data were collected from newspaper articles, television news transcripts, police reports and obituaries published between 1999 and 2005. Findings suggest the most dangerous setting was the home and the majority of perpetrators we...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Use of hyaluronic acid fillers for the treatment of the aging faceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Michael H GoldGold Skin Care Center, Tennessee Clinical Research Center, Nashville, TN, USA; Department of Medicine, Vanderbilt University Medical School,Vanderbilt University Nursing School, Nashville, TN, USA; Huashan Hospital, Fudan University, Shanghai, ChinaAbstract: Hyaluronic acid fillers have become popular soft tissue filler augmentation agents over the past several years. They have helped revolutionize the filler market with a number of new products available for use for our patients. The purpose of this manuscript is to review the characteristics of the HA fillers and to review each of the current products curre...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Review of the safety and efficacy of risedronate for the treatment of male osteoporosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Raja Bobba1, Jonathan D Adachi21Department of Medicine, St. Joseph’s Healthcare - McMaster University, 2Department of Medicine, Alliance for Better Bone Health Chair in Rheumatology, St. Joseph’s Healthcare, McMaster University, Hamilton, ON, CanadaAbstract: Osteoporosis in men is an increasingly recognized problem with associated fracture morbidity and mortality. Treatment is limited, with the bisphosphonates being the mainstay of therapy. Risedronate has demonstrated fracture efficacy in women and efficacy has been recently been investigated in men. In men, risedronate either maintains or increases bone miner...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Factors that influence exercise activity among women post hip fracture participating in the Exercise Plus ProgramEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Barbara Resnick1, Denise Orwig2, Christopher D’Adamo2, Janet Yu-Yahiro3, William Hawkes2, Michelle Shardell2, Justine Golden2, Sheryl Zimmerman4, Jay Magaziner21University of Maryland School of Nursing, 655 West Lombard Street, Baltimore, MD,21201, USA; 2University of Maryland School of Medicine, Howard Hall, Redwood Street, Baltimore MD 21201, USA; 3Department of Orthopaedic Surgery, Union Memorial Hospital, Baltimore, USA; 4University of North Carolina Chapel Hill, 301 Pittsboro St., CB#3550, Chapel Hill, NC 27599-3550, USAAbstract: Using a social ecological model, this paper describes selected intra- and interpers...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

The aging process and potential interventions to extend life expectancyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Matteo Tosato1, Valentina Zamboni1, Alessandro Ferrini1, Matteo Cesari1,21Department of Gerontology, Geriatrics and Physiatry; Catholic University of Sacred Heart, Rome, Italy; 2Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL, USAAbstract: Aging is commonly defined as the accumulation of diverse deleterious changes occurring in cells and tissues with advancing age that are responsible for the increased risk of disease and death. The major theories of aging are all specific of a particular cause of aging, providing useful and important insights for ...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

The management of hemophilia in elderly patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Massimo Franchini1, Annarita Tagliaferri2, Pier Mannuccio Mannucci31Transfusion and Hemophilia Center, City Hospital of Verona, Italy; 2Regional Reference Center for Inherited Bleeding Disorders, University Hospital of Parma, Italy; 3Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Department of Medicine and Medical Specialties, IRCCS Maggiore Hospital, Mangiagalli and Regina Elena Foundation, University of Milan, ItalyAbstract: After the increasing rate of deaths observed during the 1980s due to human immunodeficiency virus (HIV) infection, the health-related quality of life and life expectancy of persons with h...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Pathogenesis of Alzheimer’s diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Russell H SwerdlowDepartment of Neurology, University of Virginia School of Medicine, Charlottesville, VA, USAAbstract: Alzheimer’s disease (AD) is incredibly common. Increasing longevity ensures its prevalence will rise even further. Ongoing efforts to understand AD pathogenesis reveal numerous tantalizing leads. Formulating a comprehensive AD pathogenesis theory capable of incorporating these disparate leads, though, has proven difficult. This review discusses current attempts to formulate a comprehensive AD pathogenesis theory. In doing so, it focuses on clinical and molecular relationships between AD and aging. A...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Discharge destination from an acute care for the elderly (ACE) unitEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The objective of this paper is to describe placement and characteristics of older patients discharged from an acute care for the elderly (ACE) unit. The study sample consists of 1,351 men and women aged 65 years or older that were discharged from the ACE Unit during a 12-month period. The mean number of discharges per month was 109.2 ± 28.4. Most of the subjects were discharged home or home with home health 841, 62.3%. The oldest elderly and patients who had been admitted from long term care institutions or from skilled nursing facilities to the ACE unit were less likely to return to home.Keywords: hospitalization, ...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Pharmacologic management of overactive bladderEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article summarizes the efficacy, contraindications, precautions, dosing and common side effects of these agents. All available clinical trials on trospium, solifenacin and darifenacin were reviewed to determine its place in therapy.Keywords: overactive bladder, urinary incontinence, pharmacologic management, antimuscarinic agents, anticholinergics
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Vascular dementia: Pharmacological treatment approaches and perspectivesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Andrius Baskys1,3, Anthony C Hou21Department of Psychiatry and Human Behavior; 2Program in Geriatrics, University of California at Irvine, Irvine, California; 3Memory Disorders Program, VA Health Care System Long Beach, Long Beach, California, USAAbstract: Vascular dementia is a common condition for which there are no effective approved pharmacological treatments available. Absence of effective treatments creates a difficult situation for those suffering from the disease, their caregivers, and healthcare providers. This review will address our current understanding of the mechanisms of nerve cell damage due to ischemia and...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Eszopiclone for late-life insomniaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Christina S McCrae1, Amanda Ross1, Ashley Stripling2, Natalie D Dautovich21Department of Clinical and Health Psychology, 2Department of Psychology, University of Florida, Gainesville, Florida, USAAbstract: Insomnia, the most common sleep disturbance in later life, affects 20%–50% of older adults. Eszopiclone, a short-acting nonbenzodiazepine hypnotic agent developed for the treatment of insomnia, has been available in Europe since 1992 and in the US since 2005. Although not yet evaluated for transient insomnia in older adults, eszopiclone has been shown to be safe and efficacious for short-term treatment (2 weeks) of...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

The osteoporotic male: Overlooked and undermanaged?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Bruno Madeo, Lucia Zirilli, Giovanni Caffagni, Chiara Diazzi, Alessia Sanguanini, Elisa Pignatti, Cesare Carani, Vincenzo RochiraDepartment of Medicine, Endocrinology and Metabolism, and Geriatrics, University of Modena and Reggio Emilia, Ospedale S.Agostino – Estense di Baggiovara, Modena, ItalyAbstract: Age-related bone loss in men is a poorly understood phenomenon, although increasing data on the pathophysiology of bone in men is becoming available. Most of what we know on bone pathophysiology derives from studies on women. The well-known association between menopause and osteoporosis is far from been disproven. H...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Osteoporosis screening and risk managementEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Consuelo H WilkinsDepartment of Medicine, Division of Geriatrics and Nutritional Science, Washington University School of Medicine, St. Louis, MO, USAAbstract: Osteoporosis is common among older adults and results in costly osteoporotic fractures. Screening for this metabolic bone disorder is warranted in most older adults and clinicians must be diligent in identifying persons at risk. The evaluation should include an assessment of risk factors for falls, a bone density test, and consideration of possible secondary causes of osteoporosis. Several medications are available to improve bone density and decrease fractures. Ade...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Update on bazedoxifene: A novel selective estrogen receptor modulatorEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Diane M BiskobingDepartment of Medicine, Virginia Commonwealth University, Richmond, VA, USAAbstract: In the elderly population, osteoporosis is a significant clinical problem leading to disability and even death. Many patients remain untreated, despite effective therapies, because of patients’ unwillingness to take current therapies or inability to tolerate the therapies. For this reason, ongoing research continues to search for more effective and tolerable osteoporosis agents. Bazedoxifene is a selective estrogen receptor modulator (SERM) currently in development for osteoporosis prevention and treatment. A new dru...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals

Effect of estrogens on skin aging and the potential role of SERMsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Susan Stevenson1, Julie Thornton21Burns & Plastic Surgery Research Unit, 2Cutaneous Research, Medical Biosciences, School of Life Sciences, University of Bradford, Bradford, UKAbstract: In humans, structural and functional changes attributable to aging are more visibly evident in the skin than in any other organ. Estrogens have significant effects on skin physiology and modulate epidermal keratinocytes, dermal fibroblasts and melanocytes, in addition to skin appendages including the hair follicle and the sebaceous gland. Importantly, skin aging can be significantly delayed by the administration of estrogen. This paper ...
Source: Clinical Interventions in Aging - May 21, 2008 Category: Geriatrics Source Type: journals