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Statement of OwnershipEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - November 2, 2009 Category: Microbiology Source Type: news

CMN subscription advertisementEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - November 2, 2009 Category: Microbiology Source Type: news

Call for SubmissionsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
If your laboratory has isolated an uncommon organism, a common organism from an unusual patient, or an organism that presented a particular diagnostic challenge, why not share the information with your colleagues through the Clinical Microbiology Newsletter. The editors would like to receive interesting case reports from our readers for possible publication in the Newsletter. Submitted case reports should contain (i) a brief clinical history summarizing the symptoms and course of the illness, (ii) a description of how the organism(s) was cultured and differentiated from closely associated organisms, and (iii) the results o...
Source: Clinical Microbiology Newsletter - November 2, 2009 Category: Microbiology Source Type: news

Recurrent Skin Abscesses Caused by Panton-Valentine Leukocidin-Producing Methicillin-Susceptible Staphylococcus aureusEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Staphylococcus aureus is an important pathogen, and a frequent cause of community-acquired, as well as hospital-acquired, infections. The most common infections caused by S. aureus are those involving the skin and soft tissues (furuncles, cellulitis, and impetigo) and, less commonly, infections at deeper sites (bones, joints, and heart valves). Frequently, S. aureus produces toxin-mediated diseases, such as toxic shock syndrome, caused by the elaboration of toxic shock syndrome toxin 1, and food poisoning, caused by staphylococcal enterotoxins (). Another important toxin is Panton-Valentine leukocidin (PVL), which kills ne...
Source: Clinical Microbiology Newsletter - November 2, 2009 Category: Microbiology Authors: N. Van Gasse, A. Jeurissen, J. Van Schaeren, J.-P. Ursi, P. Borgers Source Type: news

Infectious Diseases and Famous People Who Succumbed to ThemEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article examines seven illnesses — tuberculosis, influenza, infectious diarrhea, syphilis, bacterial pneumonia, bacterial sepsis, and malaria, and the individuals throughout history who contracted and died from them. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - November 2, 2009 Category: Microbiology Authors: Alice S. Weissfeld Source Type: news

Infectious Disease Outbreaks on Cruise ShipsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Leisure travel by sea has existed since antiquity. Today's cruise ships serve as a gathering place for people in every age group from different countries and cultures. The closed environment aboard cruise ships, close contact among passengers and crew, and common sources of food and water provide ample opportunity for exposure to and transmission of infectious diseases. Of these, gastrointestinal and respiratory infections pose the greatest risk of outbreaks. Outbreaks on cruise ships present a public health concern, since infection is often easily spread, is difficult to control, and has the potential to di...
Source: Clinical Microbiology Newsletter - October 19, 2009 Category: Microbiology Authors: Yvette S. McCarter Source Type: news

A Special Invitation to AuthorsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The editors of Clinical Microbiology Newsletter extend an invitation to authors who may wish to contribute an article or editorial for publication in CMN. Of special interest are timely topics of interest to clinical microbiologists and infectious disease physicians. Persons with suggestions for articles or editorials should contact the Editor listed to the right to discuss the details of their potential submission. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - September 17, 2009 Category: Microbiology Source Type: news

Bacillary Angiomatosis as an Initial Presentation in an HIV-Positive ManEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 26-year-old man presented with fever, malaise, scrotal skin lesions, and inguinal lymphadenopathy. An excisional biopsy specimen from an inguinal lymph node demonstrated a florid vascular proliferation. A Warthin-Starry stain, an immunoperoxidase stain, and PCR studies confirmed the presence of Bartonella henselae. The diagnosis of bacillary angiomatosis secondary to B. henselae infection was established. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - September 17, 2009 Category: Microbiology Authors: Rossitza A. Draganova-Tacheva, Steven Domsky, Vikram Paralkar, Allan L. Truant, Matthew Hurford Source Type: news

The Laboratory's Role in Evaluating Sexually Transmitted Diseases as a Result of Sexual AbuseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article reviews the performance of molecular assays for the diagnosis of common sexually transmitted infections associated with child abuse. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - September 17, 2009 Category: Microbiology Authors: Robert L. Sautter, William D. LeBar, Earl Greenwald Source Type: news

A Special Invitation to AuthorsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The editors of Clinical Microbiology Newsletter extend an invitation to authors who may wish to contribute an article or editorial for publication in CMN. Of special interest are timely topics of interest to clinical microbiologists and infectious disease physicians. Persons with suggestions for articles or editorials should contact the Editor listed to the right to discuss the details of their potential submission. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - September 2, 2009 Category: Microbiology Source Type: news

Emerging Technologies in Nanotechnology-Based Pathogen DetectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Nanotechnology-based pathogen detection is an emerging technology that is poised to have a major impact on health care and medicine, food and agriculture, the environment, and biodefense. The technology bridges a variety of sciences, including biology, chemistry, physics, and statistics to create a new cadre of tools and capabilities that can be applied to basic and translational research, diagnostics, and commercialization. This burgeoning field has created an unprecedented array of technologies that have advanced detection, diagnosis, and imaging of chemical and biological agents and that offers the potent...
Source: Clinical Microbiology Newsletter - September 2, 2009 Category: Microbiology Authors: J.D. Driskell, R.A. Tripp Source Type: news

A Special Invitation to AuthorsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The editors of Clinical Microbiology Newsletter extend an invitation to authors who may wish to contribute an article or editorial for publication in CMN. Of special interest are timely topics of interest to clinical microbiologists and infectious disease physicians. Persons with suggestions for articles or editorials should contact the Editor listed to the right to discuss the details of their potential submission. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - August 21, 2009 Category: Microbiology Source Type: news

The Impact of Clinical Laboratory Improvement Advisory Committee Recommendations on Microbiology LaboratoriesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: The Clinical Laboratory Improvement Advisory Committee (CLIAC) was mandated by the Clinical Laboratory Improvement Amendments of 1988 (CLIA) and established in 1992 to provide advice to the Department of Health and Human Services on regulation of laboratory testing and improving laboratory quality. Since then, CLIAC has met regularly and recommended regulatory changes to CLIA, provided input on good laboratory practices, and discussed critical issues related to clinical and public health testing, the laboratory workforce, and laboratory systems research. The Committee has been effective in driving changes to...
Source: Clinical Microbiology Newsletter - August 21, 2009 Category: Microbiology Authors: Diane C. Bosse, Nancy L. Anderson, Alice S. Weissfeld Source Type: news

Call for SubmissionsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
If your laboratory has isolated an uncommon organism, a common organism from an unusual patient, or an organism that presented a particular diagnostic challenge, why not share the information with your colleagues through the Clinical Microbiology Newsletter. The editors would like to receive interesting case reports from our readers for possible publication in the Newsletter. Submitted case reports should contain (i) a brief clinical history summarizing the symptoms and course of the illness, (ii) a description of how the organism(s) was cultured and differentiated from closely associated organisms, and (iii) the results o...
Source: Clinical Microbiology Newsletter - August 6, 2009 Category: Microbiology Source Type: news

Buruli Ulcer (Mycobacterium ulcerans Infection): a Re-emerging DiseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Mycobacterium ulcerans infection is an emerging disease that causes indolent, necrotizing skin lesions known as Buruli ulcer (BU). Approximately 10% of patients develop reactive osteitis or osteomyelitis beneath skin lesions or metastatic osteomyelitis from lymphohematogenous spread of M. ulcerans. The most plausible mode of transmission is by skin trauma at sites contaminated by M. ulcerans. Pathogenesis is mediated by a necrotizing, immunosuppressive toxin produced by M. ulcerans called mycolactone. The incidence of BU is highest in children up to 15 years old and is a public health problem in countries of...
Source: Clinical Microbiology Newsletter - August 6, 2009 Category: Microbiology Authors: Douglas S. Walsh, Françoise Portaels, Wayne M. Meyers Source Type: news

A Special Invitation to AuthorsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The editors of Clinical Microbiology Newsletter extend an invitation to authors who may wish to contribute an article or editorial for publication in CMN. Of special interest are timely topics of interest to clinical microbiologists and infectious disease physicians. Persons with suggestions for articles or editorials should contact the Editor listed to the right to discuss the details of their potential submission. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - July 22, 2009 Category: Microbiology Source Type: news

A Case of Wedding-Acquired BabesiosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Babesiosis is a well-recognized disease of veterinary importance, causing infections primarily in cattle, horses, and dogs (). The first definitive case of human babesiosis, caused by the cattle parasite Babesia divergeus, was documented in a Yugoslavian farmer in 1957 (). Even though more than 100 species of Babesia have been described, only three distinct species are recognized as important causes of human disease. In Europe, most human infections are caused by B. divergeus (), whereas in the United States, Babesia microti accounts for most infections in the Northeast () and upper Midwest (). Another Babesia sp., charact...
Source: Clinical Microbiology Newsletter - July 22, 2009 Category: Microbiology Authors: Russell A. Rawling, Roger Krieger, Paul A. Granato Source Type: news

Klebsiella and Gastrointestinal Syndromes with Particular Emphasis on Klebsiella oxytoca Antibiotic-Associated ColitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: The genus Klebsiella (family Enterobacteriaceae), of which K. pneumoniae and K. oxytoca are the two most commonly isolated members, consists of gram-negative, non-motile, encapsulated rods. As opportunistic pathogens, Klebsiella spp. can cause a variety of illnesses including pneumonia, urinary tract infections, septicemia, soft tissue, intravenous, meningitis, liver abscess, and gastrointestinal disease, in the immunocompromised or those with underlying conditions. Current studies strongly suggest that klebsiellae, and in particular K. oxytoca, may also be associated with a variety of gastrointestinal syndr...
Source: Clinical Microbiology Newsletter - July 22, 2009 Category: Microbiology Authors: Nicole M. Green, Robert Tran, J. Michael Janda Source Type: news

A Special Invitation to AuthorsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The editors of Clinical Microbiology Newsletter extend an invitation to authors who may wish to contribute an article or editorial for publication in CMN. Of special interest are timely topics of interest to clinical microbiologists and infectious disease physicians. Persons with suggestions for articles or editorials should contact the Editor listed to the right to discuss the details of their potential submission. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - July 7, 2009 Category: Microbiology Source Type: news

Listerial Rhomboencephalitis: Not Just for the Weakened Immune SystemEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present the case of a previously healthy, 28-year-old male with listerial rhomboencephalitis (brainstem meningoencephalitis). (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - July 7, 2009 Category: Microbiology Authors: Heidi J. Zapata, Abhishek Bose, Waleed Javaid, Donald Blair Source Type: news

Emerging Infections: Implications for Sentinel and Public Health LaboratoriesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: After reading the popular novel, “The Cobra Event,” then U.S. President Bill Clinton, concerned with the prospect of use of a biologic agent against the United States, issued Presidential Directive 39. This executive act resulted in the formation of the Laboratory Response Network (LRN), a structured consortium of clinical, governmental, and public health laboratories. The LRN became operational in August 1999, and though few in the laboratory field noticed its birth, by the fall of 2001 and the anthrax letter events, the alliance of clinical and public health laboratories was becoming a reality. The LRN...
Source: Clinical Microbiology Newsletter - July 7, 2009 Category: Microbiology Authors: James L. Beebe, Alice S. Weissfeld Source Type: news

Bacteremia Caused by Dysgonomonas spp.: a Report of Two CasesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The genus Dysgonomonas was recently created by Hofstad et al. () to accommodate a group of fastidious gram-negative, facultative anaerobic, coccobacillus-shaped organisms. This genus constitutes a phylogenetic cluster within the Bacteroides-Prevotella-Porphyromonas group. Three species are included in the genus. Dysgonomonas gadei was first isolated from an infected human gall bladder (). Dysgonomonas capnocytophagoides has been recovered from stool samples, primarily in immunocompromised patients or those with severe underlying diseases (), and from blood and wound and abscess specimens (). This species includes organisms...
Source: Clinical Microbiology Newsletter - June 25, 2009 Category: Microbiology Authors: Marisa N. Almuzara, Roxana Cittadini, Pascual J. Ladelfa, Liliana Olivieri, Maria Soledad Ramirez, Cristian Zamponi, Angela M.R. Famiglietti, Carlos A. Vay Source Type: news

CLSI: Building Laboratory Capacity in AfricaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: The Clinical and Laboratory Standards Institute (CLSI) is a global, nonprofit, membership-driven organization dedicated to developing standards and guidelines for the health care and medical testing community. CLSI's mission is to develop best practices in clinical and laboratory testing and to promote their use throughout the world, using a consensus-driven process that balances the viewpoints of industry, government, and the health care professions. CLSI recognizes that health is the most important foreign policy issue of our time. In response to the call for laboratory capacity building, and on behalf of ...
Source: Clinical Microbiology Newsletter - June 25, 2009 Category: Microbiology Authors: Karen McClure, Judith Arbique, Anne Rendell, Patricia Rizzo-Price Source Type: news

A Special Invitation to AuthorsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The editors of Clinical Microbiology Newsletter extend an invitation to authors who may wish to contribute an article or editorial for publication in CMN. Of special interest are timely topics of interest to clinical microbiologists and infectious disease physicians. Persons with suggestions for articles or editorials should contact the Editor listed to the right to discuss the details of their potential submission. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - June 6, 2009 Category: Microbiology Source Type: news

Pneumococcal Arthritis in a ChildEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Streptococcus pneumoniae is a well-recognized human pathogen, particularly in patients in the pediatric age group. Most pediatric pneumococcal infections are localized in the respiratory tract; however, more serious, but less common, disseminated infections are well documented (). (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - June 6, 2009 Category: Microbiology Authors: Joseph B. Domachowske, Russell A. Rawling, Paul A. Granato Source Type: news

Bacillus species (not anthracis)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Bacteria of the genus Bacillus are widely distributed in nature, useful in agriculture and industry, and occasionally directly harmful to humans. The uniqueness of Bacillus relates to its ability to produce spores that can survive desiccation, heat, and cold and can germinate readily. The toxins that cause anthrax and food poisoning are encoded by plasmid-borne genes, allowing different species to have strikingly similar chromosomal DNA despite radically different phenotypes. Bacillus infections are uncommon and often associated with trauma or foreign bodies. Food poisoning caused by Bacillus spp. is much le...
Source: Clinical Microbiology Newsletter - June 6, 2009 Category: Microbiology Authors: Thomas Fekete Source Type: news

Cryptococcus gattiiEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
An 80-year-old man visited his primary care physician with the complaint of an intermittent cough for 2 to 3 years, which had become worse in the past few months. The patient was producing clear mucus with no blood. The cough was thought to be due to gastroesophageal reflux disease. The patient had a history of smoking but had quit 25 years previously and also reported a history of exposure to asbestos when he served as an electrician in the British Navy. Born and raised in England, the patient lived for 30 years in northern California and in the San Jose area. He then moved to Salem, Oregon, where he has lived for the pas...
Source: Clinical Microbiology Newsletter - May 20, 2009 Category: Microbiology Authors: Susan E. Sharp Source Type: news

American Society for Microbiology Focus on Clinical MicrobiologyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article explores the ways that ASM helps clinical microbiologists. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - May 20, 2009 Category: Microbiology Authors: Suzanne M. Leous, Peggy McNult, Jennifer Mercurio, Kenneth M. April, Lynee Galley, Nichole Ridgeway, with contributions from the following ASM staff Source Type: news

Emerging Infectious Diseases in New England from the Puritans to the PresentEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article examines these and new emerging infections. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - May 4, 2009 Category: Microbiology Authors: Mary J. Gilchrist Source Type: news

Call for SubmissionsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
If your laboratory has isolated an uncommon organism, a common organism from an unusual patient, or an organism that presented a particular diagnostic challenge, why not share the information with your colleagues through the Clinical Microbiology Newsletter. The editors would like to receive interesting case reports from our readers for possible publication in the Newsletter. Submitted case reports should contain (i) a brief clinical history summarizing the symptoms and course of the illness, (ii) a description of how the organism(s) was cultured and differentiated from closely associated organisms, and (iii) the results o...
Source: Clinical Microbiology Newsletter - April 20, 2009 Category: Microbiology Source Type: news

CLSI NewsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Wayne, Pennsylvania, USA, June 2008 — The enormous global problem of tuberculosis (with roughly one-third of the world's population infected with Mycobacterium tuberculosis), coupled with an increasing incidence of infections caused by nontuberculous mycobacteria, presents unique challenges for the laboratory diagnosis of mycobacterial infections. The diagnosis of M. tuberculosis needs to be optimized and expedited for good patient management, and appropriate control measures need to be implemented to prevent transmission of tuberculosis. There are similar demands for accurate identification of the ever-increasing number...
Source: Clinical Microbiology Newsletter - April 20, 2009 Category: Microbiology Source Type: news

Donor-Derived Infections in Transplant PatientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Numerous cases of donor-derived infections (DDI) after solid-organ transplantation have been reported in recent times. While some are expected (often due to cytomegalovirus or Epstein-Barr virus), others have been clinically unexpected. Pre-transplant screening is quite helpful in abrogating the risks of DDI but could be optimized further to increase patient safety, reduce risk, augment the number of organs transplanted, and save more lives. Testing thus far has largely been serologic; advances in testing technology have allowed the use of nucleic acid testing, as well as other new testing modalities. The op...
Source: Clinical Microbiology Newsletter - April 20, 2009 Category: Microbiology Authors: Camille Nelson Kotton Source Type: news