Medicolegal Sidebar: Nuclear Verdicts-Should Orthopaedic Surgeons Be Concerned?
Clin Orthop Relat Res. 2024 Mar 27. doi: 10.1097/CORR.0000000000003049. Online ahead of print.NO ABSTRACTPMID:38536109 | DOI:10.1097/CORR.0000000000003049 (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - March 27, 2024 Category: Orthopaedics Authors: B Sonny Bal Source Type: research

Letter to the Editor: Routine MRI Among Patients With a Suspected Scaphoid Fracture Risks Overdiagnosis
Clin Orthop Relat Res. 2024 Mar 20. doi: 10.1097/CORR.0000000000003050. Online ahead of print.NO ABSTRACTPMID:38517400 | DOI:10.1097/CORR.0000000000003050 (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - March 22, 2024 Category: Orthopaedics Authors: Joseph Bernstein Source Type: research

Are Current Survival Prediction Tools Useful When Treating Subsequent Skeletal-related Events From Bone Metastases?
CONCLUSION: The SORG-MLAs maintain satisfactory discriminatory capacity and offer considerable net benefits through decision curve analysis, indicating their continued viability as prediction tools in this clinical context. However, the algorithms overestimate 1-year survival rates for patients with a subsequent SRE of the spine, warranting consideration of specific patient groups. Clinicians and surgeons should exercise caution when using the SORG-MLAs for survival prediction in these patients and remain aware of potential mispredictions when tailoring treatment plans, with a preference for less invasive treatments. Ultim...
Source: Clinical Orthopaedics and Related Research - March 22, 2024 Category: Orthopaedics Authors: Yu-Ting Pan Yen-Po Lin Hung-Kuan Yen Hung-Ho Yen Chi-Ching Huang Hsiang-Chieh Hsieh Stein Janssen Ming-Hsiao Hu Wei-Hsin Lin Olivier Q Groot Source Type: research

Can DNA Methylation Profiling Classify Histologic Subtypes and Grades in Soft Tissue Sarcoma?
CONCLUSION: We observed a different DNA methylation pattern between soft tissue sarcomas and normal tissues. Liposarcoma was distinguished from leiomyosarcoma using methylation profiling. High-grade soft tissue sarcoma samples showed a hypermethylation pattern compared with low-grade ones. Our findings indicate the need for research using methylation profiling to better understand the diverse biological characteristics of soft tissue sarcoma. Such research should include studies with sufficient samples and a variety of subtypes, as well as analyses of the expression and function of related genes. Additionally, efforts to l...
Source: Clinical Orthopaedics and Related Research - March 22, 2024 Category: Orthopaedics Authors: Hyunho Kim Min Wook Joo Joohee Yoon Hong Sik Park June Hyuk Kim Joo Hwan Lee Sung Hwan Kim Seul Ki Lee Yang-Guk Chung Yoon Joo Cho Source Type: research

How Does ChatGPT Use Source Information Compared With Google? A Text Network Analysis of Online Health Information
CONCLUSION: ChatGPT responses are similar to individual Google Search results for queries related to orthopaedic surgery, but the distribution of source information can vary substantially based on the relative level of consensus on a topic. For example, for carpal tunnel syndrome, where there is widely accepted medical consensus, ChatGPT responses had higher similarity to academic sources and therefore used those sources more. When fewer academic or government sources are available, especially in our search related to platelet-rich plasma, ChatGPT appears to have relied more heavily on a small number of nonacademic sources...
Source: Clinical Orthopaedics and Related Research - March 22, 2024 Category: Orthopaedics Authors: Oscar Y Shen Jayanth S Pratap Xiang Li Neal C Chen Abhiram R Bhashyam Source Type: research

Letter to the Editor: Routine MRI Among Patients With a Suspected Scaphoid Fracture Risks Overdiagnosis
Clin Orthop Relat Res. 2024 Mar 20. doi: 10.1097/CORR.0000000000003050. Online ahead of print.NO ABSTRACTPMID:38517400 | DOI:10.1097/CORR.0000000000003050 (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - March 22, 2024 Category: Orthopaedics Authors: Joseph Bernstein Source Type: research

Are Current Survival Prediction Tools Useful When Treating Subsequent Skeletal-related Events From Bone Metastases?
CONCLUSION: The SORG-MLAs maintain satisfactory discriminatory capacity and offer considerable net benefits through decision curve analysis, indicating their continued viability as prediction tools in this clinical context. However, the algorithms overestimate 1-year survival rates for patients with a subsequent SRE of the spine, warranting consideration of specific patient groups. Clinicians and surgeons should exercise caution when using the SORG-MLAs for survival prediction in these patients and remain aware of potential mispredictions when tailoring treatment plans, with a preference for less invasive treatments. Ultim...
Source: Clinical Orthopaedics and Related Research - March 22, 2024 Category: Orthopaedics Authors: Yu-Ting Pan Yen-Po Lin Hung-Kuan Yen Hung-Ho Yen Chi-Ching Huang Hsiang-Chieh Hsieh Stein Janssen Ming-Hsiao Hu Wei-Hsin Lin Olivier Q Groot Source Type: research

Can DNA Methylation Profiling Classify Histologic Subtypes and Grades in Soft Tissue Sarcoma?
CONCLUSION: We observed a different DNA methylation pattern between soft tissue sarcomas and normal tissues. Liposarcoma was distinguished from leiomyosarcoma using methylation profiling. High-grade soft tissue sarcoma samples showed a hypermethylation pattern compared with low-grade ones. Our findings indicate the need for research using methylation profiling to better understand the diverse biological characteristics of soft tissue sarcoma. Such research should include studies with sufficient samples and a variety of subtypes, as well as analyses of the expression and function of related genes. Additionally, efforts to l...
Source: Clinical Orthopaedics and Related Research - March 22, 2024 Category: Orthopaedics Authors: Hyunho Kim Min Wook Joo Joohee Yoon Hong Sik Park June Hyuk Kim Joo Hwan Lee Sung Hwan Kim Seul Ki Lee Yang-Guk Chung Yoon Joo Cho Source Type: research

How Does ChatGPT Use Source Information Compared With Google? A Text Network Analysis of Online Health Information
CONCLUSION: ChatGPT responses are similar to individual Google Search results for queries related to orthopaedic surgery, but the distribution of source information can vary substantially based on the relative level of consensus on a topic. For example, for carpal tunnel syndrome, where there is widely accepted medical consensus, ChatGPT responses had higher similarity to academic sources and therefore used those sources more. When fewer academic or government sources are available, especially in our search related to platelet-rich plasma, ChatGPT appears to have relied more heavily on a small number of nonacademic sources...
Source: Clinical Orthopaedics and Related Research - March 22, 2024 Category: Orthopaedics Authors: Oscar Y Shen Jayanth S Pratap Xiang Li Neal C Chen Abhiram R Bhashyam Source Type: research

Letter to the Editor: Routine MRI Among Patients With a Suspected Scaphoid Fracture Risks Overdiagnosis
Clin Orthop Relat Res. 2024 Mar 20. doi: 10.1097/CORR.0000000000003050. Online ahead of print.NO ABSTRACTPMID:38517400 | DOI:10.1097/CORR.0000000000003050 (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - March 22, 2024 Category: Orthopaedics Authors: Joseph Bernstein Source Type: research

Are Current Survival Prediction Tools Useful When Treating Subsequent Skeletal-related Events From Bone Metastases?
CONCLUSION: The SORG-MLAs maintain satisfactory discriminatory capacity and offer considerable net benefits through decision curve analysis, indicating their continued viability as prediction tools in this clinical context. However, the algorithms overestimate 1-year survival rates for patients with a subsequent SRE of the spine, warranting consideration of specific patient groups. Clinicians and surgeons should exercise caution when using the SORG-MLAs for survival prediction in these patients and remain aware of potential mispredictions when tailoring treatment plans, with a preference for less invasive treatments. Ultim...
Source: Clinical Orthopaedics and Related Research - March 22, 2024 Category: Orthopaedics Authors: Yu-Ting Pan Yen-Po Lin Hung-Kuan Yen Hung-Ho Yen Chi-Ching Huang Hsiang-Chieh Hsieh Stein Janssen Ming-Hsiao Hu Wei-Hsin Lin Olivier Q Groot Source Type: research

Can DNA Methylation Profiling Classify Histologic Subtypes and Grades in Soft Tissue Sarcoma?
CONCLUSION: We observed a different DNA methylation pattern between soft tissue sarcomas and normal tissues. Liposarcoma was distinguished from leiomyosarcoma using methylation profiling. High-grade soft tissue sarcoma samples showed a hypermethylation pattern compared with low-grade ones. Our findings indicate the need for research using methylation profiling to better understand the diverse biological characteristics of soft tissue sarcoma. Such research should include studies with sufficient samples and a variety of subtypes, as well as analyses of the expression and function of related genes. Additionally, efforts to l...
Source: Clinical Orthopaedics and Related Research - March 22, 2024 Category: Orthopaedics Authors: Hyunho Kim Min Wook Joo Joohee Yoon Hong Sik Park June Hyuk Kim Joo Hwan Lee Sung Hwan Kim Seul Ki Lee Yang-Guk Chung Yoon Joo Cho Source Type: research

How Does ChatGPT Use Source Information Compared With Google? A Text Network Analysis of Online Health Information
CONCLUSION: ChatGPT responses are similar to individual Google Search results for queries related to orthopaedic surgery, but the distribution of source information can vary substantially based on the relative level of consensus on a topic. For example, for carpal tunnel syndrome, where there is widely accepted medical consensus, ChatGPT responses had higher similarity to academic sources and therefore used those sources more. When fewer academic or government sources are available, especially in our search related to platelet-rich plasma, ChatGPT appears to have relied more heavily on a small number of nonacademic sources...
Source: Clinical Orthopaedics and Related Research - March 22, 2024 Category: Orthopaedics Authors: Oscar Y Shen Jayanth S Pratap Xiang Li Neal C Chen Abhiram R Bhashyam Source Type: research

Letter to the Editor: Routine MRI Among Patients With a Suspected Scaphoid Fracture Risks Overdiagnosis
Clin Orthop Relat Res. 2024 Mar 20. doi: 10.1097/CORR.0000000000003050. Online ahead of print.NO ABSTRACTPMID:38517400 | DOI:10.1097/CORR.0000000000003050 (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - March 22, 2024 Category: Orthopaedics Authors: Joseph Bernstein Source Type: research

Are Current Survival Prediction Tools Useful When Treating Subsequent Skeletal-related Events From Bone Metastases?
CONCLUSION: The SORG-MLAs maintain satisfactory discriminatory capacity and offer considerable net benefits through decision curve analysis, indicating their continued viability as prediction tools in this clinical context. However, the algorithms overestimate 1-year survival rates for patients with a subsequent SRE of the spine, warranting consideration of specific patient groups. Clinicians and surgeons should exercise caution when using the SORG-MLAs for survival prediction in these patients and remain aware of potential mispredictions when tailoring treatment plans, with a preference for less invasive treatments. Ultim...
Source: Clinical Orthopaedics and Related Research - March 22, 2024 Category: Orthopaedics Authors: Yu-Ting Pan Yen-Po Lin Hung-Kuan Yen Hung-Ho Yen Chi-Ching Huang Hsiang-Chieh Hsieh Stein Janssen Ming-Hsiao Hu Wei-Hsin Lin Olivier Q Groot Source Type: research