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Severe Hypertensive Response to Atropine Therapy for Bradycardia Associated with Dexmedetomidine: Case Report and Literature Review
Clin Pharmacol. 2024 Jan 11;16:27-31. doi: 10.2147/CPAA.S436188. eCollection 2024.ABSTRACTDexmedetomidine is a selective and potent α2-adrenoceptor agonist used for sedation, analgesia, and anxiolysis, with minimal respiratory depression; therefore, it is widely used in clinical practice. Transient hypertension has been reported to be an indication for the use of dexmedetomidine. The authors report three female patients who experienced hypertensive crisis when used atropine to treat bradycardia caused by dexmedetomidine. The transient hypertension is a relatively common side effect of dexmedetomidine, hypertensive crisis ...
Source: Clinical Pharmacology: Advances and Applications - January 16, 2024 Category: Allergy & Immunology Authors: Yong Li Ju Gao Lin Jiang Canlin Sun Hua Hong Dapeng Yu Source Type: research