Machine learning in risk prediction of continuous renal replacement therapy after coronary artery bypass grafting surgery in patients
ConclusionsMachine learning models were developed to predict CRRT. This contributes to the identification of risk variables for CRRT following CABG surgery in ICU patients and enables the optimization of perioperative managements for patients. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - March 27, 2024 Category: Urology & Nephrology Source Type: research

Multicenter randomized controlled trial of intensive uric acid lowering therapy for CKD patients with hyperuricemia: TARGET-UA
ConclusionThis study did not reveal the benefit of Intensive ULT to improve albuminuria levels.(UMIN000026741 and jRCTs051180146). (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - March 26, 2024 Category: Urology & Nephrology Source Type: research

Factors affecting responsiveness of vadadustat in patients with anemia associated with chronic kidney disease: a post-hoc subgroup analysis of Japanese phase 3 randomized studies
ConclusionsIn this post-hoc analysis, several factors were identified as affecting the response to vadadustat. These results may provide useful information leading to an appropriate dose modification for vadadustat.Clinical trial registrationNCT03329196 (MT-6548-J01) and NCT03439137 (MT-6548-J03). (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - March 26, 2024 Category: Urology & Nephrology Source Type: research

AHA Life ’s Essential 8 and new-onset CKD: a prospective cohort study from the UK Biobank
ConclusionsAn elevated degree of CVH, as delineated by the discerning metric LE8, exhibited a pronounced and statistically significant correlation with a marked reduction in the likelihood of CKD occurrence. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - March 22, 2024 Category: Urology & Nephrology Source Type: research

Survey of Japanese nephrologists' use of clinical practice guidelines for rapidly progressive glomerulonephritis
ConclusionsThe survey responses revealed how Japan's new RPGN guidelines are used in actual clinical practice. Our findings will contribute to the guidelines' dissemination and implementation. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - March 22, 2024 Category: Urology & Nephrology Source Type: research

Kidney damage relates to agonal bacteremia: a single-center retrospective study
ConclusionPremortem kidney damage relates to agonal bacteremia. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - March 20, 2024 Category: Urology & Nephrology Source Type: research

Association of serum magnesium levels with renal prognosis in patients with chronic kidney disease
ConclusionBased on large real-world data, this study demonstrated that low magnesium levels are associated with poorer renal outcomes. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - March 20, 2024 Category: Urology & Nephrology Source Type: research

Correction to: AHA Life ’s Essential 8 and new‑onset CKD: a prospective cohort study from the UK Biobank
(Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - March 20, 2024 Category: Urology & Nephrology Source Type: research

Genotype –phenotype correlations in children with Gitelman syndrome
ConclusionsPatients with GS who had truncating variants in one or both alleles had more severe electrolyte abnormalities than those without truncating variants. Patients with GS who had monoallelicSLC12A3 variants on examination had almost the same phenotypes, response to treatment, and long-term prognosis as those with biallelic variants. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - March 13, 2024 Category: Urology & Nephrology Source Type: research

Impact of dietary habits on renal function in Saku, a rural Japanese town: a cohort study
ConclusionsOur cross-sectional study showed that the intake of chicken meat, natto, and plant protein was associated with high eGFR levels. This information can be of value for preventing CKD incidence in healthy Japanese individuals. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - March 12, 2024 Category: Urology & Nephrology Source Type: research

Frequency and prognosis of peritoneal dialysis-associated peritonitis in children
ConclusionsThe incidence rate of peritonitis was the highest in children under 2  years old.P. aeruginosa peritonitis is a risk factor for catheter removal and peritoneal dysfunction. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - March 12, 2024 Category: Urology & Nephrology Source Type: research

Impact of dietary habits on renal function in Saku, a rural Japanese town: a cohort study
ConclusionsOur cross-sectional study showed that the intake of chicken meat, natto, and plant protein was associated with high eGFR levels. This information can be of value for preventing CKD incidence in healthy Japanese individuals. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - March 12, 2024 Category: Urology & Nephrology Source Type: research

Left ventricular hypertrophy and left atrial diameter are associated with mortality risk in haemodialysis patients: a retrospective cohort study
ConclusionAmong maintenance haemodialysis (MHD) patients, LAD was more strongly associated with mortality than was LVH. A high LAD and LVH are associated with a greater risk of mortality. Our results emphasize that the occurrence of LAD and LVH in combination provides information that may be helpful in stratifying the risk of MHD patients. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - March 8, 2024 Category: Urology & Nephrology Source Type: research

Cellular and humoral immune responses to COVID-19 booster vaccination in Japanese dialysis patients
ConclusionsHD patients had significantly stronger cellular and humoral immune responses than the control 3  weeks after the booster dose. Our findings will help in developing better COVID-19 vaccination strategies for HD and PD patients. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - March 8, 2024 Category: Urology & Nephrology Source Type: research

Optimal course of pre-emptive rituximab administration for long-term disease remission in patients with complicated steroid-dependent nephrotic syndrome requiring immunosuppressive agents after rituximab
(Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - March 8, 2024 Category: Urology & Nephrology Source Type: research