Effectiveness and safety of filgotinib in rheumatoid arthritis patients: data from the GISEA registry
CONCLUSIONS: In an Italian real-life setting, filgotinib is confirmed to be safe and with a good effectiveness profile both in monotherapy and without glucocorticoids.PMID:38634362 | DOI:10.55563/clinexprheumatol/b40rv4 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 18, 2024 Category: Rheumatology Authors: Marco Fornaro Roberto Caporali Martina Biggioggero Serena Bugatti Ludovico De Stefano Alberto Cauli Mattia Congia Fabrizio Conti Maria Sole Chimenti Chiara Bazzani Simone Perniola Fabiola Atzeni Giovanni Lapadula Gianfranco Ferraccioli Florenzo Iannone fr Source Type: research

Uncovering risk factors for adverse events and infections in rheumatoid arthritis and rheumatoid arthritis with interstitial lung disease under treatment with biologics or targeted synthetic DMARDs: insights from the KOBIO Registry
CONCLUSIONS: Patients with RA-ILD exhibited a higher rate of b/tsDMARDs withdrawal due to overall AEs and infections than those with RA without ILD. In the RA-ILD group, older age was identified as a risk factor for overall AEs, whereas a current smoking status was identified as a risk factor for infections.PMID:38634363 | DOI:10.55563/clinexprheumatol/6h1euo (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 18, 2024 Category: Rheumatology Authors: Ji-Won Kim Kichul Shin Juyang Jung Chang-Hee Suh Jinhyun Kim Sun-Kyung Lee Hyoun-Ah Kim Source Type: research

Endothelial mesenchymal transition promotes pannus formation in ankylosing spondylitis by  activation of TGF-β/SMAD signalling pathway
CONCLUSIONS: Our findings show that EndMT is involved in the promotion of pannus formation by TGF-β/SMAD signalling pathway activation in AS.PMID:38634365 | DOI:10.55563/clinexprheumatol/9u1vzp (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 18, 2024 Category: Rheumatology Authors: Shaojie Li Zhiduo Hou Yao Gong Jianhua Peng Hongjin Liang Danmin Wang Ling Lin Source Type: research

Analysis of risk factors associated with diffuse alveolar haemorrhage in patients with ANCA-associated vasculitis and construction of a risk prediction model using line graph
CONCLUSIONS: The new nomogram, which included age, Hb, ESR, PLT and haematuria as variables, had the potential to predict the risk of AAV patients complicated with DAH.PMID:38634373 | DOI:10.55563/clinexprheumatol/7m21vr (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 18, 2024 Category: Rheumatology Authors: Xuanwei Li Congyuan Ma Jiamei Xu Meng Zhang Qin Xiang Yue Li Wenlai Li Ping Zhu Source Type: research

Lower total cholesterol and triglyceride levels in ankylosing spondylitis than non-inflammatory rheumatic disease controls in a 1978-98 study: a potential effect of increased physical energetics in manual occupations in the pre-2000 chronologic era
CONCLUSIONS: In the 1978-98 survey, AS had significantly lower mean serum cholesterol and triglyceride levels than NIRD control patients. Associated manual labour occupations may have significantly contributed to results, possibly related to increased energy expenditures from physical activity in the pre-2000 era.PMID:38634375 | DOI:10.55563/clinexprheumatol/u41mn1 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 18, 2024 Category: Rheumatology Authors: Alfonse T Masi Ponnaiah C Mohan Tsr Murugan Chadrick R Evans Michael J Ryan Megan L Brezka Vaughn Hanna Gerald R Cooper Jean C Aldag Source Type: research

Effectiveness and safety of filgotinib in rheumatoid arthritis patients: data from the GISEA registry
CONCLUSIONS: In an Italian real-life setting, filgotinib is confirmed to be safe and with a good effectiveness profile both in monotherapy and without glucocorticoids.PMID:38634362 | DOI:10.55563/clinexprheumatol/b40rv4 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 18, 2024 Category: Rheumatology Authors: Marco Fornaro Roberto Caporali Martina Biggioggero Serena Bugatti Ludovico De Stefano Alberto Cauli Mattia Congia Fabrizio Conti Maria Sole Chimenti Chiara Bazzani Simone Perniola Fabiola Atzeni Giovanni Lapadula Gianfranco Ferraccioli Florenzo Iannone fr Source Type: research

Uncovering risk factors for adverse events and infections in rheumatoid arthritis and rheumatoid arthritis with interstitial lung disease under treatment with biologics or targeted synthetic DMARDs: insights from the KOBIO Registry
CONCLUSIONS: Patients with RA-ILD exhibited a higher rate of b/tsDMARDs withdrawal due to overall AEs and infections than those with RA without ILD. In the RA-ILD group, older age was identified as a risk factor for overall AEs, whereas a current smoking status was identified as a risk factor for infections.PMID:38634363 | DOI:10.55563/clinexprheumatol/6h1euo (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 18, 2024 Category: Rheumatology Authors: Ji-Won Kim Kichul Shin Juyang Jung Chang-Hee Suh Jinhyun Kim Sun-Kyung Lee Hyoun-Ah Kim Source Type: research

Endothelial mesenchymal transition promotes pannus formation in ankylosing spondylitis by  activation of TGF-β/SMAD signalling pathway
CONCLUSIONS: Our findings show that EndMT is involved in the promotion of pannus formation by TGF-β/SMAD signalling pathway activation in AS.PMID:38634365 | DOI:10.55563/clinexprheumatol/9u1vzp (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 18, 2024 Category: Rheumatology Authors: Shaojie Li Zhiduo Hou Yao Gong Jianhua Peng Hongjin Liang Danmin Wang Ling Lin Source Type: research

Analysis of risk factors associated with diffuse alveolar haemorrhage in patients with ANCA-associated vasculitis and construction of a risk prediction model using line graph
CONCLUSIONS: The new nomogram, which included age, Hb, ESR, PLT and haematuria as variables, had the potential to predict the risk of AAV patients complicated with DAH.PMID:38634373 | DOI:10.55563/clinexprheumatol/7m21vr (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 18, 2024 Category: Rheumatology Authors: Xuanwei Li Congyuan Ma Jiamei Xu Meng Zhang Qin Xiang Yue Li Wenlai Li Ping Zhu Source Type: research

Lower total cholesterol and triglyceride levels in ankylosing spondylitis than non-inflammatory rheumatic disease controls in a 1978-98 study: a potential effect of increased physical energetics in manual occupations in the pre-2000 chronologic era
CONCLUSIONS: In the 1978-98 survey, AS had significantly lower mean serum cholesterol and triglyceride levels than NIRD control patients. Associated manual labour occupations may have significantly contributed to results, possibly related to increased energy expenditures from physical activity in the pre-2000 era.PMID:38634375 | DOI:10.55563/clinexprheumatol/u41mn1 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 18, 2024 Category: Rheumatology Authors: Alfonse T Masi Ponnaiah C Mohan Tsr Murugan Chadrick R Evans Michael J Ryan Megan L Brezka Vaughn Hanna Gerald R Cooper Jean C Aldag Source Type: research

Effectiveness and safety of filgotinib in rheumatoid arthritis patients: data from the GISEA registry
CONCLUSIONS: In an Italian real-life setting, filgotinib is confirmed to be safe and with a good effectiveness profile both in monotherapy and without glucocorticoids.PMID:38634362 | DOI:10.55563/clinexprheumatol/b40rv4 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 18, 2024 Category: Rheumatology Authors: Marco Fornaro Roberto Caporali Martina Biggioggero Serena Bugatti Ludovico De Stefano Alberto Cauli Mattia Congia Fabrizio Conti Maria Sole Chimenti Chiara Bazzani Simone Perniola Fabiola Atzeni Giovanni Lapadula Gianfranco Ferraccioli Florenzo Iannone fr Source Type: research

Uncovering risk factors for adverse events and infections in rheumatoid arthritis and rheumatoid arthritis with interstitial lung disease under treatment with biologics or targeted synthetic DMARDs: insights from the KOBIO Registry
CONCLUSIONS: Patients with RA-ILD exhibited a higher rate of b/tsDMARDs withdrawal due to overall AEs and infections than those with RA without ILD. In the RA-ILD group, older age was identified as a risk factor for overall AEs, whereas a current smoking status was identified as a risk factor for infections.PMID:38634363 | DOI:10.55563/clinexprheumatol/6h1euo (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 18, 2024 Category: Rheumatology Authors: Ji-Won Kim Kichul Shin Juyang Jung Chang-Hee Suh Jinhyun Kim Sun-Kyung Lee Hyoun-Ah Kim Source Type: research

Endothelial mesenchymal transition promotes pannus formation in ankylosing spondylitis by  activation of TGF-β/SMAD signalling pathway
CONCLUSIONS: Our findings show that EndMT is involved in the promotion of pannus formation by TGF-β/SMAD signalling pathway activation in AS.PMID:38634365 | DOI:10.55563/clinexprheumatol/9u1vzp (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 18, 2024 Category: Rheumatology Authors: Shaojie Li Zhiduo Hou Yao Gong Jianhua Peng Hongjin Liang Danmin Wang Ling Lin Source Type: research

Analysis of risk factors associated with diffuse alveolar haemorrhage in patients with ANCA-associated vasculitis and construction of a risk prediction model using line graph
CONCLUSIONS: The new nomogram, which included age, Hb, ESR, PLT and haematuria as variables, had the potential to predict the risk of AAV patients complicated with DAH.PMID:38634373 | DOI:10.55563/clinexprheumatol/7m21vr (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 18, 2024 Category: Rheumatology Authors: Xuanwei Li Congyuan Ma Jiamei Xu Meng Zhang Qin Xiang Yue Li Wenlai Li Ping Zhu Source Type: research

Lower total cholesterol and triglyceride levels in ankylosing spondylitis than non-inflammatory rheumatic disease controls in a 1978-98 study: a potential effect of increased physical energetics in manual occupations in the pre-2000 chronologic era
CONCLUSIONS: In the 1978-98 survey, AS had significantly lower mean serum cholesterol and triglyceride levels than NIRD control patients. Associated manual labour occupations may have significantly contributed to results, possibly related to increased energy expenditures from physical activity in the pre-2000 era.PMID:38634375 | DOI:10.55563/clinexprheumatol/u41mn1 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 18, 2024 Category: Rheumatology Authors: Alfonse T Masi Ponnaiah C Mohan Tsr Murugan Chadrick R Evans Michael J Ryan Megan L Brezka Vaughn Hanna Gerald R Cooper Jean C Aldag Source Type: research