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Admission blood pressure indexes and risk of in-hospital death and dependency among acute hemorrhagic stroke patients, Inner Mongolia, China.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Increased SBP, DBP, MAP and PP at admission were all associated with in-hospital mortality, and increased SBP, DBP and MAP were associated with dependency at discharge among hemorrhagic stroke patients. PMID: 19796570 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - October 4, 2009 Category: Biomedical Science Authors: Zhang H, Ju Z, Xu T, Tong W, Jin E, Wang N, Zhang Y Tags: Clin Invest Med Source Type: journals

Protective effects of vitamin E on central nervous system in streptozotocin-induced diabetic rats.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The study revealed neuroprotective effects of VE on ischemic damage in diabetic central neuronal cells, caused by diabetic oxidative stress. PMID: 19796571 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - October 4, 2009 Category: Biomedical Science Authors: Kabay SC, Ozden H, Guven G, Ustuner MC, Degirmenci I, Olgun EG, Unal N Tags: Clin Invest Med Source Type: journals

Arrhythmic effects of ivabradine in patients with coronary artery disease.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: There is no relationship between ivabradine therapy and increased risk of ventricular and atrial arrhythmia in coronary artery disease patient. PMID: 19796572 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - October 4, 2009 Category: Biomedical Science Authors: Murat SN, Orcan S, Akdemir R, Dogan M, Kara E, Balci M Tags: Clin Invest Med Source Type: journals

Oxidative status and paraoxonase activity in children with asthma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: In asthmatic children, when total oxidant status, total antioxidant capacity and lipid hydroperoxidation levels increase, paraoxonase activity decreased. PMID: 19796573 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - October 4, 2009 Category: Biomedical Science Authors: Cakmak A, Zeyrek D, Atas A, Selek S, Erel O Tags: Clin Invest Med Source Type: journals

Angiogenic study in Graves' disease treated with thyroid arterial embolization.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Thyroid arterial embolization can decrease the expression of VEGF, bFGF and MVD. Consequently, angiogenesis within the GD thyroid will be decreased in the long term after embolization and may serve as the basis for reduced thyroid size and function. PMID: 19796574 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - October 4, 2009 Category: Biomedical Science Authors: Zhao W, Gao BL, Liu ZY, Yi GF, Shen LJ, Yang HY, Li H, Song DP, Jiang YN, Hu JH, Luo G Tags: Clin Invest Med Source Type: journals

Susceptibility to apoptosis of lymphocytes from patients with peripheral arterial disease.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The results of this study of lymphocyte apoptosis are important in understanding of the disease pathogenesis and should be taken into account in elaboration of treatment strategies. PMID: 19796575 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - October 4, 2009 Category: Biomedical Science Authors: Skórkowska-Telichowska K, Adamiec R, Tuchendler D, Gasiorowski K Tags: Clin Invest Med Source Type: journals

Panton-Valentine leukocidin in pediatric community-acquired Staphylococcus aureus infections.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: In a clonally heterogeneous population of pediatric community-acquired SA infections, pvl+ strains were associated with abscess formation and erythromycin susceptibility, but not invasive disease. PMID: 19796576 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - October 4, 2009 Category: Biomedical Science Authors: Papenburg J, Fontela P, Raynal L, Jetté L, Ismail J, Bekal S, Al-Zahrani I, Quach C Tags: Clin Invest Med Source Type: journals

Cigarette smoking and chronic low back pain in the adult population.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Daily smoking increases the risk of LBP among young adults, and this effect seems to be dose-dependent. Back pain treatment programs may benefit from integrating smoking habit modification. Further research is required to develop effective prevention strategies. PMID: 19796577 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - October 4, 2009 Category: Biomedical Science Authors: Alkherayf F, Agbi C Tags: Clin Invest Med Source Type: journals

Cytotoxicity of natural extract from Tegillarca granosa on ovarian cancer cells is mediated by multiple molecules.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: HSS has a potential cytotoxic effect on human ovarian cancer cells, which was mediated by multiple signal molecules including bcl-2, caspase-3, beta-catenin, and CD24. These findings will provide a theoretical basis for HSS's potential clinical application as a novel marine anti-cancer agent. PMID: 19796578 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - October 4, 2009 Category: Biomedical Science Authors: Gao MQ, Han YT, Zhu L, Chen SG, Hong ZY, Wang CB Tags: Clin Invest Med Source Type: journals

Distraction osteogenesis is inhibited by cancer radiotherapy with Co 60.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Radiotherapy has a negative effect on distraction osteogenesis, even if performed on a different part of the bone. PMID: 19796579 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - October 4, 2009 Category: Biomedical Science Authors: Kesemenli CC, Kaya H, Memisoglu K, Kaya B, Dirier A, Tosun B, Kilinc N Tags: Clin Invest Med Source Type: journals

Liver X receptors as potential therapeutic targets in atherosclerosis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: LXR beta-selective agonists and LXR modulators, which act as agonists in macrophages and induce cholesterol efflux while as antagonists of lipogenesis in the liver, are two critical and attractive approaches to treat atherosclerosis and cardiovascular diseases. PMID: 19796580 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - October 4, 2009 Category: Biomedical Science Authors: Zhu Y, Li Y Tags: Clin Invest Med Source Type: journals

CSCI/RCPSC HENRY FRIESEN LECTURE: Clinical research in Canada: the dawn of a new era?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In response to the growing gap between discovery and the optimal application of medical advancements to health care delivery, countries the world over have developed large and well funded programs to reduce these gaps. Although these programs vary in nature, they have generally largely focused more on reducing the gap in bench to bedside research. Canada's strong biomedical and patient oriented research (POR) community has a strong base from which to build, but requires support in order to fill the missing elements needed to take full advantage of the important unmet needs in health related research. In Canada, a coali...
Source: Clinical and Investigative Medicine - October 4, 2009 Category: Biomedical Science Authors: Rouleau JL Tags: Clin Invest Med Source Type: journals

JOE DOUPE LECTURE: Cardiac troponin in the intensive care unit.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Cardiac troponin elevation is common and observed in 40 to 50% of critically ill medical and surgical patients. Elevated levels appear to identify patients at increased risk for death in the intensive care unit or hospital setting. This finding, and its relation to myocardial infarction and acute coronary syndromes, requires prospective study to better understand the implications for diagnosis and management. PMID: 19796582 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - October 4, 2009 Category: Biomedical Science Authors: Lim W Tags: Clin Invest Med Source Type: journals

Prevalence and duration of exercise induced albuminuria in healthy people.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: A short period, 15-20 min, of maximal exercise leads to A/C ratios above the microalbuminuria threshold in a substantial proportion of normal subjects. Physicians should not measure urine albumin in patients who give a history of such activity in the past 24 hr. PMID: 19640328 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - August 1, 2009 Category: Biomedical Science Authors: Heathcote KL, Wilson MP, Quest DW, Wilson TW Tags: Clin Invest Med Source Type: journals

Serum levels of p53 and cytochrome c in subjects with type 2 diabetes and impaired glucose tolerance.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The present study shows that the serum level of p53 is lower in the patients with type 2 diabetes than in controls or in subjects with IGT. No difference was seen among the the groups for the serum level of cytochrome c. PMID: 19640329 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - August 1, 2009 Category: Biomedical Science Authors: Dincer Y, Himmetoglu S, Yalin S, Damci T, Ilkova H, Akcay T Tags: Clin Invest Med Source Type: journals

Adiponectin has different mechanisms in type 1 and type 2 diabetes with C-peptide link.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Adiponectin levels were higher in type 1 diabetes. The association between C-peptide and adiponectin is probably one of the reasons for their different respective levels in different types of diabetes. Interrelations between adiponectin and inflammation, dyslipidemia, C-peptide levels and sex appear to be important for complex adiponectin modulation and action. PMID: 19640330 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - August 1, 2009 Category: Biomedical Science Authors: Ljubic S, Boras J, Jazbec A, Lovrencic MV, Vidjak V, Erzen DJ, Mileta D Tags: Clin Invest Med Source Type: journals

Effect of simvastatin on plasma interleukin-6 in patients with unstable angina.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Short-term treatment with simvastatin reduces plasma IL-6. The anti-inflammatory effect of simvastatin may contribute to its beneficial effects on the ventricular function and angina control. PMID: 19640331 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - August 1, 2009 Category: Biomedical Science Authors: Ren HZ, Ma LL, Wang LX Tags: Clin Invest Med Source Type: journals

Right ventricular function in ST elevation myocardial infarction: effect of reperfusion.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: RV function deteriorated in STEMI compared with healthy controls. Contrary to the expectation, RV dysfunction was observed in anterior STEMI, but not in non anterior MI. There was no difference in RV function between the two treatment modalities. PMID: 19640332 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - August 1, 2009 Category: Biomedical Science Authors: Karakurt O, Akdemir R Tags: Clin Invest Med Source Type: journals

Potential role of matrix metalloproteinase-2,-9 and tissue inhibitors of metalloproteinase-1,-2 in exudative pleural effusions.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Determination of TIMP-2 in pleural fluid may contribute to differentiate TP from MP. These results suggest that overproduction of MMP-9 and TIMP-2 is associated with accumulation of the pleural effusion in malignancy. Further studies with a greater number of patients are needed to confirm this hypothesis. PMID: 19640333 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - August 1, 2009 Category: Biomedical Science Authors: Vatansever S, Gelisgen R, Uzun H, Yurt S, Kosar F Tags: Clin Invest Med Source Type: journals

Immunological disturbances in Good's syndrome.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Measurement of serum immunoglobulin concentration is recommended for all patients suspected of thymoma. PMID: 19640334 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - August 1, 2009 Category: Biomedical Science Authors: Fijolek J, Wiatr E, Demkow U, Orlowsk TM Tags: Clin Invest Med Source Type: journals

Protective effect of glycyrrhizin on nephrotic syndrome induced by adriamycin in rats.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Glycyrrhizin exerts protective effects in rats with NS, reducing the excretion of Upr, Ch, BUN, sCr, and mean arterial blood pressure, and also decreasing expression of LN, FN, Col, TGF?1 and CTGF in the kidney. Renal function is improved and the severity of NS is lessened. PMID: 19558898 [PubMed - as supplied by publisher] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - June 30, 2009 Category: Biomedical Science Authors: Li Y, Bi X, Zhu G, Han Z, Ye Y, Liang Y, Zhang L, Hao Z, Zeng G, He H, Zhong W Tags: Clin Invest Med Source Type: journals

Arterial baroreflex function in older adults with neurocardiogenic syncope.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Older adults with neurocardiogenic syncope have exaggerated arterial baroreflex sensitivity at baseline. PMID: 19480734 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - June 28, 2009 Category: Biomedical Science Authors: Madden KM, Lockhart C Tags: Clin Invest Med Source Type: journals

Predictors of time to remission and treatment failure in patients with Graves' disease treated with propylthiouracil.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The time to remission in Graves patients treated with propylthiouracil can be predicted using age, serum free thyroxine and superior thyroid artery flow rate. This may help early consideration of alternative treatment for the patients requiring prolonged treatment for remission or for those who fail medical treatment. This would decrease unnecessary, long-term propylthiouracil exposure with its serious side effects. PMID: 19480735 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - June 28, 2009 Category: Biomedical Science Authors: Cinemre H, Bilir C, Gokosmanoglu F, Akdemir N, Erdogmus B, Buyukkaya R Tags: Clin Invest Med Source Type: journals

Peptidic sequence "HSEAETGPP" is recognized by the sera of pars planitis patients.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: These results suggest that the peptide HSEAETGPP is associated with PP. PMID: 19480736 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - June 28, 2009 Category: Biomedical Science Authors: Castañeda-Sánchez JI, Curiel-Quesada E, Pedrosa-Seres M, Cancino-Diaz ME, Rodríguez-Martínez S, Cancino-Diaz JC Tags: Clin Invest Med Source Type: journals

Quality of life, depression, and cytokine patterns in patients with chronic hepatitis C treated with antiviral therapy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: BDI, SF-12, IL-4 and ferritin are good tools to predict the appearance of depressive symptoms and worsening of the quality of life in the HCV+ population. PMID: 19480737 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - June 28, 2009 Category: Biomedical Science Authors: Falasca K, Mancino P, Ucciferri C, Dalessandro M, Manzoli L, Pizzigallo E, Conti CM, Vecchiet J Tags: Clin Invest Med Source Type: journals

Atorvastatin reduces the expression of aldo-keto reductases in HUVEC and PTEC. A new approach to influence the polyol pathway.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The reduction of members of the aldo-keto-reductase family by atorvastatin is a novel way to influence the polyol pathway and a new pleiotropic effect of atorvastatin. PMID: 19480738 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - June 28, 2009 Category: Biomedical Science Authors: Ruf TF, Quintes S, Sternik P, Gottmann U Tags: Clin Invest Med Source Type: journals

Wait times for surgical and adjuvant radiation treatment of breast cancer in Canada and the United States: greater socioeconomic inequity in America.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: This historical study contextualized Canada's "waiting-list problems" with evidence on breast cancer care, where lower income Americans seemed to have waited as long as similar Canadians. Many more low-income Americans seemed to experience the longest wait of all for adjuvant care. They simply did not receive it. In contrast to stark American socioeconomic inequity, this study evidenced remarkable equity in Canadian breast cancer care. PMID: 19480739 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - June 28, 2009 Category: Biomedical Science Authors: Gorey KM, Luginaah IN, Holowaty EJ, Fung KY, Hamm C Tags: Clin Invest Med Source Type: journals

Co-expression of ER-beta and HER2 associated with poorer prognosis in primary breast cancer.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Both ER-beta positive and HER2 positive status was associated with poorer overall survival (OS) by univariate analysis. In both HER2 positive and HER2 negative subgroups, ER-beta positive was associated with poorer distant disease free survival (DDFS) but not OS, which implied that ER-beta might relate to metastasis in breast cancer. PMID: 19480740 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - June 28, 2009 Category: Biomedical Science Authors: Qui WS, Yue L, Ding AP, Sun J, Yao Y, Shen Z, Fan LH Tags: Clin Invest Med Source Type: journals

Protective effect of glycyrrhizin on nephrotic syndrome induced by adriamycin in rats.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Glycyrrhizin exerts protective effects in rats with NS, reducing the excretion of Upr, Ch, BUN, sCr, and mean arterial blood pressure, and also decreasing expression of LN, FN, Col, TGFbeta1 and CTGF in the kidney. Renal function is improved and the severity of NS is lessened. PMID: 19480741 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - June 28, 2009 Category: Biomedical Science Authors: Bi X, Zhu G, Han Z, Ye Y, Liang Y, Zhang L, Hao Z, Zeng G, He H, Zhong W Tags: Clin Invest Med Source Type: journals

Overexpression of CIRP may reduce testicular damage induced by cryptorchidism.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Overexpression of CIRP may reduce testicular damage induced by cryptorchidism by down-regulating the levels of p53 and Fas. PMID: 19331798 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - April 11, 2009 Category: Biomedical Science Authors: Zhou KW, Zheng XM, Yang ZW, Zhang L, Chen HD Tags: Clin Invest Med Source Type: journals

Effects of GSM-like radiofrequency on distortion product otoacoustic emissions in pregnant adult rabbits.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: GSM-like RFR caused decreases in DPOAE amplitudes mainly in non-pregnant adult rabbits. Prolonged exposure may affect the DPOAE amplitude. Recommendations are given to prevent the potential hazardous effects of RF in humans. PMID: 19331799 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - April 11, 2009 Category: Biomedical Science Authors: Budak GG, Muluk NB, Oztürk GG, Budak B, Apan A, Seyhan N, Sanli C Tags: Clin Invest Med Source Type: journals

Effect of Haishengsu on transplanted K562 and drug-resistant K562/ADM tumors: an experimental study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Haishengsu inhibits the growth of transplanted K562 tumours in mice. It is also effective in suppressing the growth of drug-resistant K562/ADM tumors in this animal model. PMID: 19331800 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - April 11, 2009 Category: Biomedical Science Authors: Liu JZ, Yang M, Li DP, Zhang B, Chen SG, Wang CB, Li GY, Wang LX Tags: Clin Invest Med Source Type: journals

Evaluation of metalloproteinase 2 and 9 levels and their inhibitors in combined dyslipidemia.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Combined hyperlipidemic patients have increased levels of prothrombotic and microinflammatory parameters and higher levels of MMP-2, MMP-9, TIMP-1, and TIMP-2 than control subjects. The prognostic importance of this observation has to be evaluated in adequately designed prospective studies. PMID: 19331801 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - April 11, 2009 Category: Biomedical Science Authors: Derosa G, Maffioli P, D'Angelo A, Salvadeo SA, Ferrari I, Fogari E, Gravina A, Mereu R, Palumbo I, Randazzo S, Cicero AF Tags: Clin Invest Med Source Type: journals

Effects of estrogens on oxidative protein damage in plasma and tissues in ovariectomised rats.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: The study showed the extent of oxidative protein damage (OPD) in this model of estrogen deficiency. The protective effect of estrogens against tissue specific OPD suggests that estrogens play an important role within the antioxidant defense systems in plasma, liver and brain. The exact molecular mechanisms leading to these findings are not yet completely known. Meanwhile, hormone replacement therapy for the prevention of OPD in a tissue specific manner may be required. PMID: 19331802 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - April 11, 2009 Category: Biomedical Science Authors: Topçuoglu A, Uzun H, Balci H, Karakus M, Coban I, Altug T, Aydin S, Topçuoglu D, Cakatay U Tags: Clin Invest Med Source Type: journals

The prevalence of Th17 cells in patients with dilated cardiomyopathy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Th17 function is increased in patients with DCM, suggesting a role for Th17 cells in the pathogenesis of DCM. PMID: 19331803 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - April 11, 2009 Category: Biomedical Science Authors: Yi A, Jian L, Xiaojing H, Hui X Tags: Clin Invest Med Source Type: journals

Admission blood glucose and in-hospital clinical outcome among patients with acute stroke in Inner Mongolia, China.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Increased admission blood glucose was associated with death/dependency among patients with acute hemorrhagic and ischemic stroke. PMID: 19331804 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - April 11, 2009 Category: Biomedical Science Authors: Wang N, Qiao D, Tong W, Zhang F, Ju Z, Xu T, Jin E, Zhang H, Zhang Y Tags: Clin Invest Med Source Type: journals

Graves' disease treated with thyroid arterial embolization.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Thyroid arterial embolization can cause GD thyroid gland a series of pathological changes of acute ischemia and necrosis and later, chronic inflammation, fibroplasia and atrophy to decrease secretion of thyroid. The pathological changes within the thyroid gland after embolization form the basis of thyroid arterial embolization in treating GD hyperthyroidism. PMID: 19331805 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - April 11, 2009 Category: Biomedical Science Authors: Zhao W, Gao BL, Tian M, Yi GF, Yang HY, Shen LJ, Li H, Shen J Tags: Clin Invest Med Source Type: journals

Stem cells and models of astrocytomas.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The quest to develop robust pre-clinical models of astrocytomas is on an ongoing basis. The models are of clinical importance for the discovery of effective treatment modalities that can considerably improve the health of patients with this deadly disease. PMID: 19331806 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - April 11, 2009 Category: Biomedical Science Authors: Kamnasaran D Tags: Clin Invest Med Source Type: journals

Expression of Ezrin correlates with lung metastasis in Chinese patients with osteosarcoma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Our data suggest that Ezrin, but not CD44 and Six1, could be a prognostic factor and a predictor of potential lung metastasis in osteosarcoma. Further large sample studies need to be done to confirm the potential value of Ezrin as a new therapeutic target. PMID: 19331807 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - April 11, 2009 Category: Biomedical Science Authors: Xu-Dong S, Zan S, Shui-er Z, Li-na T, Wen-xi Y, Feng L, Yang Y Tags: Clin Invest Med Source Type: journals

An alternative kinase activity assay for primary cultures derived from clinical isolates.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: This assay avoids many of the pitfalls associated with the currently available kinase protocols as well as labour-intensive mass-spectrometry analysis by specialist laboratories. We propose that this approach may be a viable alternative for clinical research laboratories aiming to measure the activity of kinases in clinical isolates. PMID: 19331809 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - April 11, 2009 Category: Biomedical Science Authors: McLean K, Wu Y, Gan BS, O'Gorman DB Tags: Clin Invest Med Source Type: journals

Keloid scarring, but not Dupuytren's contracture, is associated with unexplained carotid atherosclerosis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Keloid scarring is a clinical clue to excess atherosclerosis not explained by traditional risk factors. Such patients may benefit from therapy directed at targets related to signalling molecules common to both the process of keloid scarring and atherosclerosis. These findings suggest previously unexplored possibilities for the prevention and treatment of atherosclerosis. The differences between Dupuytren's and keloid scars that may identify such targets are discussed. PMID: 19331810 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - April 11, 2009 Category: Biomedical Science Authors: Bhavsar S, Nimigan A, Hackam DG, O'Gorman DB, Gan BS, Spence JD Tags: Clin Invest Med Source Type: journals

Comparison of pharmacokinetics of L-carnitine, acetyl-L-carnitine and propionyl-L-carnitine after single oral administration of L-carnitine in healthy volunteers.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: L-carnitine has a greater maximum plasma concentration than ALC and PLC. L-carnitine also has a longer half-life than ALC and PLC. These data may have important implications in the designing of dosing regimens for L-carnitine or its analogues, such as ALC or PLC. PMID: 19178874 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - February 4, 2009 Category: Biomedical Science Authors: Cao Y, Wang YX, Liu CJ, Wang LX, Han ZW, Wang CB Tags: Clin Invest Med Source Type: journals

Terazosin treatment suppresses basic fibroblast growth factor expression in the rat ventral prostate.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: These findings implicate the reduction of bFGF expression by terazosin as a potential additional molecular mechanism of its action that may include alterations in peptide growth factor mediated prostate homeostasis. PMID: 19178873 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - January 31, 2009 Category: Biomedical Science Authors: Mitropoulos D, Kyroudi-Voulgari A, Christelli E, Zervas A, Karayannacos P Tags: Clin Invest Med Source Type: journals

Comparison of pharmacokinetics of L-carnitine, Acetyl-L-carnitine and Propionyl-Lcarnitine after single oral administration of L-carnitine in healthy volunteers.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: L-carnitine has a greater maximum plasma concentration than ALC and PLC. L-carnitine also has a longer half-life than ALC and PLC. These data may have important implications in the designing of dosing regimens for L-carnitine or its analogues, such as ALC or PLC. PMID: 19178874 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - January 31, 2009 Category: Biomedical Science Authors: Cao Y, Wang YX, Liu CJ, Wang LX, Han ZW, Wang CB Tags: Clin Invest Med Source Type: journals

Serum IgA1 from patients with IgA nephropathy up-regulates integrin-linked kinase synthesis and inhibits adhesive capacity in podocytes through indirect pathways.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Serum IgA1 from IgAN patients may inhibit adhesive capacity and up-regulate ILK synthesis in podocytes through indirect pathways. PMID: 19178875 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - January 31, 2009 Category: Biomedical Science Authors: Ye ZC, Wang C, Tang Y, Liu X, Peng H, Zhang H, Lou TQ Tags: Clin Invest Med Source Type: journals

Connecting KCNQ1 mutants with clinical outcome.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: This study details the process of building a quantitative relationship between KCNQ1 mutations and clinical outcome and provides the probability of LQT1 in the presence of a mutation. PMID: 19178876 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - January 31, 2009 Category: Biomedical Science Authors: Yan S, Wu G Tags: Clin Invest Med Source Type: journals

Inability of healthy subjects to deposit potassium during hypokinesia and potassium supplementation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Muscle K+ content is not decreased by the K+ deficient diet and K+ loss is not increased by the higher muscle K+ content in the body. Rather it is caused by the inability of the body to use K+ during HK and K+ supplementation. PMID: 19178877 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - January 31, 2009 Category: Biomedical Science Authors: Zorbas YG, Kakuris KK, Federenko YF, Deogenov VA Tags: Clin Invest Med Source Type: journals

Seroprevalence of Toxoplasma gondii, rubella and cytomegalovirus among pregnant women in western region of Turkey.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Widespread population screening may contribute to the prevention of congenital infections due to TORCH agents. Because of the high seropositivity of T. gondii, rubella and CMV in pregnant women, preventive measures should be taken. PMID: 19178878 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - January 31, 2009 Category: Biomedical Science Authors: Tamer GS, Dundar D, Caliskan E Tags: Clin Invest Med Source Type: journals

Haemodialysis through a cellulose membrane induces dephosphorylation of CD11b and promotes leukocyte adhesion to endothelial cells.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Leukocyte activation during HD through a cellulose membrane occurs with decreases in CD11b phosphorylation. Activation also induces increases in CD11b expression associated with enhanced leukocyte adhesion to uremic endothelial cells. PMID: 19178879 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - January 31, 2009 Category: Biomedical Science Authors: Hernandez ER, Fuste B, Cases A, Tonda R, Escolar G, Ordinas A, Diaz-Ricart M Tags: Clin Invest Med Source Type: journals

Methicillin-resistant S. aureus colonization in Mexican children attending day care centres.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: We documented the presence of MRSA strain colonizing children attending DCCs in Mexico, mainly in the south and north regions of the country. Clone A and B which are closely related represented 45 % of the total of MRSA isolates. We found both, SCCmec type II and type IV strains in the three regions. PMID: 19178880 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - January 31, 2009 Category: Biomedical Science Authors: Velázquez-Guadarrama N, Martinez-Aguilar G, Galindo JA, Zuñiga G, Arbo-Sosa A Tags: Clin Invest Med Source Type: journals