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Unlocking the power of global collaboration: building a stronger evidence ecosystem together
Cochrane Database Syst Rev. 2024 Apr 16;4:ED000166. doi: 10.1002/14651858.ED000166.NO ABSTRACTPMID:38623686 | DOI:10.1002/14651858.ED000166 (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - April 16, 2024 Category: General Medicine Authors: Zoe Jordan Vivian Welch Karla Soares-Weiser Source Type: research

Midwife continuity of care models versus other models of care for childbearing women
CONCLUSIONS: Women receiving midwife continuity of care models were less likely to experience a caesarean section and instrumental birth, and may be less likely to experience episiotomy. They were more likely to experience spontaneous vaginal birth and report a positive experience. The certainty of some findings varies due to possible risks of bias, inconsistencies, and imprecision of some estimates. Future research should focus on the impact on women with social risk factors, and those at higher risk of complications, and implementation and scaling up of midwife continuity of care models, with emphasis on low- and middle-...
Source: Cochrane Database of Systematic Reviews - April 10, 2024 Category: General Medicine Authors: Jane Sandall Cristina Fernandez Turienzo Declan Devane Hora Soltani Paddy Gillespie Simon Gates Leanne V Jones Andrew H Shennan Hannah Rayment-Jones Source Type: research

Workplace interventions to reduce the risk of SARS-CoV-2 infection outside of healthcare settings
CONCLUSIONS: We are uncertain whether a test-based attendance policy affects rates of PCR-positive SARS-CoV-2 infection (any infection; symptomatic infection) compared to standard 10-day self-isolation amongst school and college staff. A test-based attendance policy may result in little to no difference in absenteeism rates compared to standard 10-day self-isolation. The non-randomised study included in our updated search did not report any outcome of interest for this Cochrane review. As a large part of the population is exposed in the case of a pandemic, an apparently small relative effect that would not be worthwhile fr...
Source: Cochrane Database of Systematic Reviews - April 10, 2024 Category: General Medicine Authors: Alexandru Marian Constantin Kukuh Noertjojo Isolde Sommer Ana Beatriz Pizarro Emma Persad Solange Durao Barbara Nussbaumer-Streit Damien M McElvenny Sarah Rhodes Craig Martin Olivia Sampson Karsten Juhl J ørgensen Matteo Bruschettini Source Type: research

Wolbachia-carrying Aedes mosquitoes for preventing dengue infection
CONCLUSIONS: The included trial demonstrates the potential significant impact of wMel-Wolbachia-carrying Ae aegypti mosquitoes on preventing dengue infection in an endemic setting, and supports evidence reported in non-randomized and uncontrolled studies. Further trials across a greater diversity of settings are required to confirm whether these findings apply to other locations and country settings, and greater reporting of acceptability and cost are important.PMID:38597256 | PMC:PMC11005084 | DOI:10.1002/14651858.CD015636.pub2 (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - April 10, 2024 Category: General Medicine Authors: Tilly Fox Yanina Sguassero Marty Chaplin Winsley Rose Dyna Doum Ingrid Arevalo-Rodriguez Gemma Villanueva Source Type: research

Corticosteroids for the prevention and treatment of bronchopulmonary dysplasia: an overview of systematic reviews
CONCLUSIONS: This overview summarises the evidence of nine SRs investigating the effect of postnatal corticosteroids in preterm infants at risk for BPD. Late initiated (≥ seven days after birth) systemic administration of dexamethasone is considered an effective intervention to reduce the risk of BPD in infants with a high risk profile for BPD, based on a favourable balance between benefits and harms. Endotracheal instillation of corticosteroids (budesonide) with surfactant as a carrier is a promising intervention, based on the beneficial effect on desirable outcomes without (so far) negative side effects. Pending result...
Source: Cochrane Database of Systematic Reviews - April 10, 2024 Category: General Medicine Authors: Moniek van de Loo Anton van Kaam Martin Offringa Lex W Doyle Chris Cooper Wes Onland Source Type: research

Orthodontic treatment for prominent lower front teeth (Class III malocclusion) in children
CONCLUSIONS: Moderate-certainty evidence showed that non-surgical orthodontic treatments (which included facemask, reverse Twin Block, orthodontic removable traction appliance, chin cup, tandem traction bow appliance and mandibular headgear) improved the bite and jaw relationship immediately post-treatment. Low-certainty evidence showed surgical orthodontic treatments were also effective. One study measured longer-term outcomes and found that the benefit from facemask was reduced three years after treatment, and appeared to be lost by six years. However, participants receiving facemask treatment were judged by clinicians t...
Source: Cochrane Database of Systematic Reviews - April 10, 2024 Category: General Medicine Authors: Darren Owens Simon Watkinson Jayne E Harrison Sarah Turner Helen V Worthington Source Type: research

Midwife continuity of care models versus other models of care for childbearing women
CONCLUSIONS: Women receiving midwife continuity of care models were less likely to experience a caesarean section and instrumental birth, and may be less likely to experience episiotomy. They were more likely to experience spontaneous vaginal birth and report a positive experience. The certainty of some findings varies due to possible risks of bias, inconsistencies, and imprecision of some estimates. Future research should focus on the impact on women with social risk factors, and those at higher risk of complications, and implementation and scaling up of midwife continuity of care models, with emphasis on low- and middle-...
Source: Cochrane Database of Systematic Reviews - April 10, 2024 Category: General Medicine Authors: Jane Sandall Cristina Fernandez Turienzo Declan Devane Hora Soltani Paddy Gillespie Simon Gates Leanne V Jones Andrew H Shennan Hannah Rayment-Jones Source Type: research

Workplace interventions to reduce the risk of SARS-CoV-2 infection outside of healthcare settings
CONCLUSIONS: We are uncertain whether a test-based attendance policy affects rates of PCR-positive SARS-CoV-2 infection (any infection; symptomatic infection) compared to standard 10-day self-isolation amongst school and college staff. A test-based attendance policy may result in little to no difference in absenteeism rates compared to standard 10-day self-isolation. The non-randomised study included in our updated search did not report any outcome of interest for this Cochrane review. As a large part of the population is exposed in the case of a pandemic, an apparently small relative effect that would not be worthwhile fr...
Source: Cochrane Database of Systematic Reviews - April 10, 2024 Category: General Medicine Authors: Alexandru Marian Constantin Kukuh Noertjojo Isolde Sommer Ana Beatriz Pizarro Emma Persad Solange Durao Barbara Nussbaumer-Streit Damien M McElvenny Sarah Rhodes Craig Martin Olivia Sampson Karsten Juhl J ørgensen Matteo Bruschettini Source Type: research

Wolbachia-carrying Aedes mosquitoes for preventing dengue infection
CONCLUSIONS: The included trial demonstrates the potential significant impact of wMel-Wolbachia-carrying Ae aegypti mosquitoes on preventing dengue infection in an endemic setting, and supports evidence reported in non-randomized and uncontrolled studies. Further trials across a greater diversity of settings are required to confirm whether these findings apply to other locations and country settings, and greater reporting of acceptability and cost are important.PMID:38597256 | PMC:PMC11005084 | DOI:10.1002/14651858.CD015636.pub2 (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - April 10, 2024 Category: General Medicine Authors: Tilly Fox Yanina Sguassero Marty Chaplin Winsley Rose Dyna Doum Ingrid Arevalo-Rodriguez Gemma Villanueva Source Type: research

Corticosteroids for the prevention and treatment of bronchopulmonary dysplasia: an overview of systematic reviews
CONCLUSIONS: This overview summarises the evidence of nine SRs investigating the effect of postnatal corticosteroids in preterm infants at risk for BPD. Late initiated (≥ seven days after birth) systemic administration of dexamethasone is considered an effective intervention to reduce the risk of BPD in infants with a high risk profile for BPD, based on a favourable balance between benefits and harms. Endotracheal instillation of corticosteroids (budesonide) with surfactant as a carrier is a promising intervention, based on the beneficial effect on desirable outcomes without (so far) negative side effects. Pending result...
Source: Cochrane Database of Systematic Reviews - April 10, 2024 Category: General Medicine Authors: Moniek van de Loo Anton van Kaam Martin Offringa Lex W Doyle Chris Cooper Wes Onland Source Type: research

Orthodontic treatment for prominent lower front teeth (Class III malocclusion) in children
CONCLUSIONS: Moderate-certainty evidence showed that non-surgical orthodontic treatments (which included facemask, reverse Twin Block, orthodontic removable traction appliance, chin cup, tandem traction bow appliance and mandibular headgear) improved the bite and jaw relationship immediately post-treatment. Low-certainty evidence showed surgical orthodontic treatments were also effective. One study measured longer-term outcomes and found that the benefit from facemask was reduced three years after treatment, and appeared to be lost by six years. However, participants receiving facemask treatment were judged by clinicians t...
Source: Cochrane Database of Systematic Reviews - April 10, 2024 Category: General Medicine Authors: Darren Owens Simon Watkinson Jayne E Harrison Sarah Turner Helen V Worthington Source Type: research

Midwife continuity of care models versus other models of care for childbearing women
CONCLUSIONS: Women receiving midwife continuity of care models were less likely to experience a caesarean section and instrumental birth, and may be less likely to experience episiotomy. They were more likely to experience spontaneous vaginal birth and report a positive experience. The certainty of some findings varies due to possible risks of bias, inconsistencies, and imprecision of some estimates. Future research should focus on the impact on women with social risk factors, and those at higher risk of complications, and implementation and scaling up of midwife continuity of care models, with emphasis on low- and middle-...
Source: Cochrane Database of Systematic Reviews - April 10, 2024 Category: General Medicine Authors: Jane Sandall Cristina Fernandez Turienzo Declan Devane Hora Soltani Paddy Gillespie Simon Gates Leanne V Jones Andrew H Shennan Hannah Rayment-Jones Source Type: research

Workplace interventions to reduce the risk of SARS-CoV-2 infection outside of healthcare settings
CONCLUSIONS: We are uncertain whether a test-based attendance policy affects rates of PCR-positive SARS-CoV-2 infection (any infection; symptomatic infection) compared to standard 10-day self-isolation amongst school and college staff. A test-based attendance policy may result in little to no difference in absenteeism rates compared to standard 10-day self-isolation. The non-randomised study included in our updated search did not report any outcome of interest for this Cochrane review. As a large part of the population is exposed in the case of a pandemic, an apparently small relative effect that would not be worthwhile fr...
Source: Cochrane Database of Systematic Reviews - April 10, 2024 Category: General Medicine Authors: Alexandru Marian Constantin Kukuh Noertjojo Isolde Sommer Ana Beatriz Pizarro Emma Persad Solange Durao Barbara Nussbaumer-Streit Damien M McElvenny Sarah Rhodes Craig Martin Olivia Sampson Karsten Juhl J ørgensen Matteo Bruschettini Source Type: research

Wolbachia-carrying Aedes mosquitoes for preventing dengue infection
CONCLUSIONS: The included trial demonstrates the potential significant impact of wMel-Wolbachia-carrying Ae aegypti mosquitoes on preventing dengue infection in an endemic setting, and supports evidence reported in non-randomized and uncontrolled studies. Further trials across a greater diversity of settings are required to confirm whether these findings apply to other locations and country settings, and greater reporting of acceptability and cost are important.PMID:38597256 | PMC:PMC11005084 | DOI:10.1002/14651858.CD015636.pub2 (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - April 10, 2024 Category: General Medicine Authors: Tilly Fox Yanina Sguassero Marty Chaplin Winsley Rose Dyna Doum Ingrid Arevalo-Rodriguez Gemma Villanueva Source Type: research

Corticosteroids for the prevention and treatment of bronchopulmonary dysplasia: an overview of systematic reviews
CONCLUSIONS: This overview summarises the evidence of nine SRs investigating the effect of postnatal corticosteroids in preterm infants at risk for BPD. Late initiated (≥ seven days after birth) systemic administration of dexamethasone is considered an effective intervention to reduce the risk of BPD in infants with a high risk profile for BPD, based on a favourable balance between benefits and harms. Endotracheal instillation of corticosteroids (budesonide) with surfactant as a carrier is a promising intervention, based on the beneficial effect on desirable outcomes without (so far) negative side effects. Pending result...
Source: Cochrane Database of Systematic Reviews - April 10, 2024 Category: General Medicine Authors: Moniek van de Loo Anton van Kaam Martin Offringa Lex W Doyle Chris Cooper Wes Onland Source Type: research