Combinatorial Chemistry and High Throughput Screening This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

IL-7R Expression Correlates with Prognosis in Breast Cancer
CONCLUSION: IL-7R emerges as a potential prognostic indicator for breast cancer patients, particularly in sustaining the immunoactive status of the tumor microenvironment (TME) and contributing to immune reconstitution. These findings offer novel insights into breast cancer treatment strategies.PMID:38638044 | DOI:10.2174/0113862073293963240409040110 (Source: Combinatorial Chemistry and High Throughput Screening)
Source: Combinatorial Chemistry and High Throughput Screening - April 19, 2024 Category: Chemistry Authors: Xiaojie Yu Hao Zhang Jing Liu Changran Hou Haojie Zhang Zhenlin Yang Source Type: research

Topological Insights into Nanostar Dendrimers by Computing the Augmented Zagreb Index
CONCLUSION: Developing the augmented Zagreb index for nanostar dendrimers is a significant breakthrough in nanobiotechnology. Based on the correlation between the calculated topological index and the corresponding molecular attributes, our analytical approach has opened up new possibilities for designing and synthesizing dendrimers tailored to specific functions in medical and material science applications. This precise topological quantification could significantly enhance the utility and functionalization of dendrimers in cutting-edge nanotechnological applications.PMID:38639273 | DOI:10.2174/0113862073291384240408074601...
Source: Combinatorial Chemistry and High Throughput Screening - April 19, 2024 Category: Chemistry Authors: Haleemah Ghazwani Ali N A Koam Muhammad Faisal Nadeem Ali Ahmad Source Type: research

Integrated Bioinformatics and Experimental Validation to Identify a Disulfidptosis-Related lncRNA Model for Prognostic Prediction in Papillary Renal Cell Carcinoma
CONCLUSION: This study successfully established and validated a novel disulfidptosis-related prediction model. The findings suggest the potential involvement of immune-related pathways in lncRNA signature-associated survival. This model holds promise for differentiating prognosis and improving personalized therapeutic strategies for pRCC in clinical practice.PMID:38639274 | DOI:10.2174/0113862073303084240403051346 (Source: Combinatorial Chemistry and High Throughput Screening)
Source: Combinatorial Chemistry and High Throughput Screening - April 19, 2024 Category: Chemistry Authors: Yidong Zhu Xiaoyi Jin Jun Liu Source Type: research

A Review of Traditional Use, Constituent Analysis, Bioactivity, and Application of Volatile Oils from Elsholtzia
CONCLUSION: The contents of traditional use, constituent analysis, bioactivity, and application of volatile oils from Elsholtzia were reviewed in this paper. This will provide important research value and a scientific basis for the in-depth study of the plants of Elsholtzia in the future.PMID:38623976 | DOI:10.2174/0113862073301745240403051205 (Source: Combinatorial Chemistry and High Throughput Screening)
Source: Combinatorial Chemistry and High Throughput Screening - April 16, 2024 Category: Chemistry Authors: Dul Dram Jia-Zeng Guo Rong-Rui Wei Qin-Ge Ma Source Type: research

Exploring the Constituents and Mechanisms of < em > Polygonum multiflorum < /em > Thunb. in Mitigating Ischemic Stroke: A Network Pharmacology and Molecular Docking Study
This study contributes new insights into the potential development of PMT for stroke prevention and treatment.PMID:38623977 | DOI:10.2174/0113862073285988240229081558 (Source: Combinatorial Chemistry and High Throughput Screening)
Source: Combinatorial Chemistry and High Throughput Screening - April 16, 2024 Category: Chemistry Authors: Lingyu Ruan Mengyun Zheng Xinru Xia Chaofan Pang Yating Wang Zhiwei Fan Jingtian Yang Qing Qing Hongyan Lin Yuheng Tao Junsong Wang Liqun Wang Source Type: research

Syringic Acid Attenuates the IL-1 β-Induced Akt Pathway in Chondrocyte ATDC5 Cells
CONCLUSION: This study revealed that SA is a novel candidate applicable for the treatment of OA.PMID:38616762 | DOI:10.2174/0113862073286384240227053954 (Source: Combinatorial Chemistry and High Throughput Screening)
Source: Combinatorial Chemistry and High Throughput Screening - April 15, 2024 Category: Chemistry Authors: Xiao-Feng He Zhi-Hong Xiong Qing-Gang Zhao Yi-Hao Lei Annamali Vijayalakshmi Gang Cheng Source Type: research

Exploring the Mechanism of KLF15 on the Biological Activity and Autophagy of Gastric Cancer Cells based on PI3K/Akt/Mtor Signaling Pathway
CONCLUSION: Overexpression of KLF15 can inhibit the proliferation and invasion of Gastric cancer cells and promote cell apoptosis and autophagy, and its mechanism may be related to the regulation of the PI3K/Akt/mTOR signaling pathway.PMID:38591199 | DOI:10.2174/0113862073255591231213053101 (Source: Combinatorial Chemistry and High Throughput Screening)
Source: Combinatorial Chemistry and High Throughput Screening - April 9, 2024 Category: Chemistry Authors: Xu Wang Jiang Liu Shihang Xi Xuan Pan Xiaosan Fang Source Type: research

Electroacupuncture can Modify Stress, Low-Grade Inflammation in the Duodenum, and Damage to the Intestinal Barrier in Rats with Functional Dyspepsia through the CRF Signaling Pathway
CONCLUSION: EA has been shown to improve the stress state of FD rats, inhibit the activation of mast cells in the duodenum, and reduce low-grade inflammatory response and damage to the intestinal mucosal barrier. It is believed that EA achieves these effects by modulating the expression of CRF and its receptors in the brain-gut interaction pathway through the CRF signaling pathway. This provides a new approach to treating FD.PMID:38591200 | DOI:10.2174/0113862073306526240403063736 (Source: Combinatorial Chemistry and High Throughput Screening)
Source: Combinatorial Chemistry and High Throughput Screening - April 9, 2024 Category: Chemistry Authors: Tong Liu Haili Wang Jiayi Liu Ruirui Tan Lili Chen Xurong Liang Ailin Li Chenxi Qi Zhaohui Wang Source Type: research